YaleCourses

Frontiers of Biomedical Engineering (BENG 100)

Uploaded 18-11-08

Professor Saltzman describes the processes of fertilization and embryogenesis. Professor Saltzman then talks about the definition and classification of different types of stem cells, where stem cells are found in the body, and the potential for use of stem cells in treating diseases. Some challenges in this type of therapy are also discussed. Finally, Professor Saltzman introduces the exponential equation for cell growth, dX/dt = eμt, and the concept of cell "doubling time."

00:00 - Chapter 1. Fertilization and Early Development
11:50 - Chapter 2. Development of S...

Ever wondered what powers the incredible force behind a rocket launch? In this lesson, we dive deep into chemical rockets, exploring the two primary types: solid and liquid propellant systems. We'll uncover what makes an ideal rocket fuel and examine the distinct advantages and disadvantages of each system, along with their real-world applications in space missions.

Uploaded 28-08-25

🎯 Learning Objectives
• Differentiate between solid and liquid chemical rockets and their propellants
• Identify the key characteristics that define a good rocket fuel
• Compare and contrast the pros and cons of solid versus liquid rocket en...

France Since 1871 (HIST 276)

Uploaded 21-11-08

The Industrial Revolution in France is often said to have been entirely overshadowed by British industrial development. This analysis is inaccurate because it ignores the significance of domestic and other non-factory occupations. Indeed, it was the class of artisan workers, rather than industrial factory workers, who were first responsible for the organization of labor movements. One of the great innovations of the factory was the imposition of industrial discipline, against which many workers rebelled, often in the form of strikes.

00:00 - Chapter 1. The Specific Nature of French...

Why is power so critical for satellites in orbit? In this lesson, we delve into the essential role of electrical power, focusing on how solar panels convert sunlight into electricity for these crucial spacecraft. We'll explore the advantages of solar panels in space, the clever techniques satellites use to maximize sun exposure, and why rechargeable batteries are indispensable for maintaining continuous operation, even when a satellite passes through Earth's shadow. Discover the differences between Earth and space-based solar power, and learn about alternative power sources for specific missions.

Uploaded 28-08-25

🎯 Learning Objectives
• Understand the c...

What happens when parents or caregivers don’t agree on how to handle behavior? It’s a common challenge that can undermine even the best intentions. In this lesson, Dr. Kazdin explains how to manage differences without creating confusion or conflict. Learn how to stay consistent, support each other’s efforts, and work toward a nurturing family environment, even when your approaches don’t always align.

Uploaded 06-08-25

🎯 Learning Objectives
• Understand how conflicting approaches can impact behavior change
• Learn strategies for staying consistent when caregivers aren’t fully aligned
• Discover how to support each oth...

Have you ever wondered how satellites manage to survive the brutal journey of launch and the harsh vacuum of space? In this lesson, we explore the critical process of integrating individual satellite components and the extensive testing required to ensure their flawless operation. From simulating extreme temperature fluctuations in a thermal vacuum chamber to enduring intense vibrations on a shake table, learn why rigorous testing is the key to a satellite's success.

Uploaded 28-08-25

🎯 Learning Objectives
• Understand the challenges of integrating satellite components built separately.
• Explain the critical importance of rigorous testing for sat...

In this lesson, we delve into the crucial guidance documents from the International Medical Device Regulators Forum (IMDRF) concerning Software as a Medical Device (SaMD). We explore the definition of SaMD, its role as independent software running on general-purpose hardware, and the significant impact it has on the medical device landscape. The discussion also covers the IMDRF's risk-based classification system for SaMD, examining how devices are categorized from Class 1 to Class 4 based on their importance to clinical management and the severity of the patient's condition, illustrated with practical examples.

Uploaded 12-08-25

🎯 Learning Objectives
• Defin...

Professors David Blight, Beverly Gage, and Joanne Freeman gathered at the Yale Teaching Studios to discuss Professor Freeman's Week 1 lectures on the pre-revolutionary period.

Uploaded 19-09-25

This podcast is also available on Apple:
https://podcasts.apple.com/us/podcast/america-at-250-the-podcast/id1840422776
and Spotify:
https://open.spotify.com/show/4C8qfQf21r4eO6mVUFguG2

To view all the videos in this course or view and download a copy of the course syllabus with required readings please scroll through the page at this link:
https://president.yale.edu/committees-programs...

Principles of Evolution, Ecology and Behavior (EEB 122)

Uploaded 01-09-09

Speciation is the process through which species diverge from each other and/or from a common ancestor. There are several definitions of species, most of which focus on reproductive isolation and/or phylogenetic similarities. This can cause some controversy. Speciation can result from geographical separation or ecological specialization. There are stages of speciation in which organisms cluster first into distinct populations before finally becoming different species.

00:00 - Chapter 1. Introduction
03:38 - Chapter 2. Diversity and How Speciation Happens
17:13 - Chapter 3. Concepts and Criteria...

The Civil War and Reconstruction (HIST 119)

Uploaded 21-11-08

Professor Blight begins his lecture with a description of the sea change in Civil War scholarship heralded by the Social History revolution of the 1960s and 1970s. Along with a focus on the experience of the common solider, women, and African Americans, a central component of this shift in scholarly emphasis was an increased interest in the effects of the war on the Union and Confederate home fronts. After suggesting some of the ways in which individual Americans experienced the war, Professor Blight moves to a...

In this lesson, join Professor Mariam Aboian for a practical demonstration of Electronic Health Records (EHR) and Picture Archiving and Communication Systems (PACS). Discover how these essential digital tools have replaced traditional paper charts and film-based imaging, streamlining patient data access, enhancing diagnostic capabilities, and improving overall clinical workflows in modern healthcare. Learn about the seamless integration of patient information and advanced imaging analysis, including emerging AI applications, that are transforming medical practice.

Uploaded 19-08-25

🎯 Learning Objectives
• Navigate the key features and functionalities of an Electronic Health Record (EHR) system.
• Understand how Picture...

Financial Markets (ECON 252)

Uploaded 19-11-08

Real Estate is the biggest asset class and of great importance for both individuals and institutional investors. An array of economic and psychological factors impact real estate investment decisions and the public has changing ideas of real estate as a profitable investment. People's demand to buy a home by taking on long-term debt, called a mortgage, is often tied with the overall health of the economy and financial markets. In recessions, home buying tends to fall and the opposite holds in a strong economy. Commercial real estate, held indirectly...

Financial Markets (ECON 252)

Uploaded 19-11-08

Mr. Carl Icahn, a prominent activist investor in corporate America, talks about his career and how he became interested in finance and involved in shareholder activism. He discusses his thoughts about today's economy and American businesses and their inherent threats and opportunities. He believes that the biggest challenge facing corporate America is weak management and that today's CEOs, with exceptions, might not be the most capable of leading global companies. He sees opportunities for current, intelligent college students to succeed in the corporate world if they work hard and...

Frontiers of Biomedical Engineering (BENG 100)

Uploaded 18-11-08

Professor Saltzman reviews the pharmacokinetic first-order rate equation that can be used to model changes in drug concentration in the blood, as well as its derivation from the law of conservation of mass. The importance of maintaining a drug concentration that is sufficient for therapeutic purpose, but below a toxic level, is emphasized. Since this is directly affected by drug administration method, ways to localize and sustain therapeutic concentrations of drug, such as incorporating in slow-releasing, biocompatible polymers are introduced. Professor Saltzman gave some examples of clinical...

Beyond just your revenue model, how do customers pay for your offering? In this lesson, we explore the different payment models that can significantly impact your social enterprise, focusing on how financing, transaction mechanisms, and payment structures can make your services more accessible and affordable for your target audience.

Uploaded 13-08-25

🎯 Learning Objectives
• Understand the concept of payment models as distinct from revenue models.
• Identify different financing approaches used in social enterprises, such as spreading payments over time.
• Recognize various transaction mechanisms and how they differ across regions.
• Explore different payment str...

Have you ever wondered what keeps satellites in orbit? In this lesson, we delve into Johannes Kepler's groundbreaking three laws of orbital motion, which explain how objects like planets and satellites move through space. We'll explore why orbits are elliptical, how orbital speed varies, and critically, how Kepler's Third Law allows us to calculate an object's distance based on its orbital period, demonstrated vividly through the case of Sputnik.

Uploaded 28-08-25

🎯 Learning Objectives
• Explain Kepler's First Law of orbital motion and its significance.
• Describe the relationship between an object's orbital period and its dis...

Financial Markets (ECON 252)

Uploaded 19-11-08

Professor Summers, former U. S. Treasury Secretary and former President of Harvard University, in this the first of two lectures in honor of former Yale Professor and Council of Economic Advisors chairman Arthur Okun, offers thoughts on the role of monetary policy in economic fluctuations, past and present. In the "Okun period," ending about when Okun died in 1980, the monetary authorities were very much involved in actually creating economic contractions. Inflation would repeatedly get out of control, the Fed would hit the brakes, and the economy would slow. But...

🎥 This clip is part of a recurring case study that follows a patient during a routine pain medicine follow-up appointment, where underlying substance use concerns gradually come to light. The scenario highlights how these issues can surface in everyday clinical practice and how providers can respond with empathy and care.

Uploaded 05-08-25

📚 About the Course
This course is designed with a singular goal: to improve the care you provide to your patients with substance use disorders. By delving into a model case performed by actors, seven Yale instructors from various fields provide techniques to scr...

Ever wondered what makes a pitch truly compelling, whether you have 10 minutes or just 30 seconds? In this lesson, we break down the art of pitching, guiding you through different formats—from comprehensive 10-slide decks to concise elevator pitches—and revealing the essential elements needed to captivate your audience and effectively communicate your social venture's vision.

Uploaded 13-08-25

🎯 Learning Objectives
• Outline the key components of a comprehensive 10-slide pitch deck.
• Differentiate between full-length, 5-minute, and lightning/elevator pitch formats and their core elements.
• Learn how to effectively present your venture's challenge, opportunity, solution, and...

Financial Markets (ECON 252)

Uploaded 19-11-08

The exchanges in which stocks and other securities are traded serve an important function in finance. They bring together people interested in buying and selling securities in order to create a universal price. Brokers and dealers are also an important part of the system, their methods and standards are ultimately behind the success of the exchanges. Many information innovations have advanced the functioning of exchanges, going all the way back to the ticker machine, which was created to communicate the price of securities at a point in time to...

Professors David Blight, Beverly Gage, and Joanne Freeman discuss Professor Freeman's Week 2 lectures on the Federalists (don't call them papers) and whether anyone would actually like the real Alexander Hamilton.

Uploaded 26-09-25

This podcast is also available on Apple:
https://podcasts.apple.com/us/podcast/america-at-250-the-podcast/id1840422776

and Spotify:
https://open.spotify.com/show/4C8qfQf21r4eO6mVUFguG2

To view all the videos in this course or view and download a copy of the course syllabus with required readings please scroll through the page at this...

France Since 1871 (HIST 276)

Uploaded 21-11-08

Anarchists, unlike syndicalists and other leftists, seek to destroy the state rather than to capture state power for themselves. Emile Henry and other late nineteenth-century radicals inaugurated the modern practice of terrorism in their individualism and their indiscriminate choice of civilian targets. Despite the terrifying consequences of individual acts of terrorism, these pale in comparison to the consequences of state terrorism.

00:00 - Chapter 1. The Roots of Anarchism: Founders and the French Context
12:59 - Chapter 2. The Legacy of Ravachol
18:51 - Chapter 3. The Story of Émile Henry: T...

America at 250: A History. Class 3 “Declaring Independence”

Uploaded 18-09-25

Professor Joanne Freeman continues her exploration of the American Experiment with an inside view of the deliberations leading to the Declaration of Independence.
 
Recorded in Yale’s Battell Chapel. This one-time-only course examines U.S. history from 1776 to the present, in advance of the nation’s semiquincentennial (or 250th birthday) in 2026. Taught jointly by Professors Joanne Freeman, David Blight, and Beverly Gage, the course emphasizes the history of the nation-state and the contested nature of American national identity. All three scholars will deliver the course’...

Introduction to Theory of Literature (ENGL 300)

Uploaded 01-09-09

In this lecture, Professor Paul Fry examines acts of reading and interpretation by way of the theory of hermeneutics. The origins of hermeneutic thought are traced through Western literature. The mechanics of hermeneutics, including the idea of a hermeneutic circle, are explored in detail with reference to the works of Hans-George Gadamer, Martin Heidegger, and E. D. Hirsch. Particular attention is paid to the emergence of concepts of "historicism" and "historicality" and their relation to hermeneutic theory.

00:00 - Chapter 1. The History of Hermeneutics
10:32...

In this lesson, you'll discover two powerful frameworks for evaluating social entrepreneurship ideas: the AAAQ Checklist and the Theory of Change. These tools help to strengthen your concepts, prevent unintended consequences like poverty traps, and rigorously test assumptions to ensure your solution creates meaningful social impact.

Uploaded 13-08-25

🎯 Learning Objectives
• Understand the purpose and components of the AAAQ Checklist (Availability, Accessibility, Acceptability, Quality).
• Learn how to apply the AAAQ Checklist to evaluate social enterprise ideas.
• Comprehend the structure and utility of the Theory of Change framework.
• Utilize the Theory of Change to l...

Why are you here? In this lesson, we dive deep into uncovering your individual purpose, an essential step for a meaningful career and successful job search. You'll explore powerful tools and worksheets designed to help you reflect on your past, envision your future, understand your intrinsic motivations, and ultimately craft a clear, impactful mission statement to guide your next professional steps.

Uploaded 03-10-25

🎯 Learning Objectives
• Explore the significance of individual purpose in career and leadership.
• Complete a personal purpose worksheet by reflecting on past choices, personal attributes, and future horizons.
• Identify your "flo...

Principles of Evolution, Ecology and Behavior (EEB 122)

Uploaded 01-09-09

Evolution plays an important though underutilized role in medicine. Evolution guides how our bodies respond to various treatments, how pathogens will respond to treatments, and how pathogens' responses will change over time. Pathogens oftentimes will evolve to an intermediate level of virulence where they become strong enough to infect a host and reproduce, but not so strong as to kill the host before it can spread the pathogen.

00:00 - Chapter 1. Introduction
06:40 - Chapter 2. "Thrifty Phenotypes"
11:36 - Chapter 3. Auto-immune Diseases in Developed...

Frontiers/Controversies in Astrophysics (ASTR 160)

Uploaded 07-10-08

Professor Bailyn offers a review of what is known so far about the expansion of the universe from observing galaxies, supernovae, and other celestial phenomena. The rate of the expansion of the universe is discussed along with the Big Rip theory and the balance of dark energy and dark matter in the universe over time. The point at which the universe shifts from accelerating to decelerating is examined. Worries related to the brightness of high redshift supernovae and the effects of gravitational lensing are explained. The lecture...

In this video, meet Teresa Chahine, the instructor for this Social Entrepreneurship Course. She shares her extensive background in public health and community-based action, working globally across various sectors. Learn about her passion for creating solutions, which led her to develop the course's unique ten-stage framework for building impact.

Uploaded 13-08-25

🎯 Learning Objectives
• Understand Teresa Chahine's background and role as the course instructor.
• Learn about her global experience in public health and community-based action, including her work with Alfanar Venture Philanthropy.
• Discover the motivation behind creating the course's ten-stage framework for building...

Is space as far away as you imagine? This lesson delves into the fascinating question of where space truly begins, moving beyond common perceptions to uncover the scientific and policy-driven boundaries that define this critical point. You'll learn about the internationally recognized Karman line and discover just how surprisingly close space actually is.

Uploaded 28-08-25

🎯 Learning Objectives
• Define the Karman line and its significance as the international boundary of space.
• Compare the international definition of space with NASA's definition.
• Explain why there is no "super obvious" end to Earth's atmosphere.
• Understand...

In this lesson, we delve deep into the Individual Purpose worksheet, explaining the profound 'why' behind each question. You'll learn how to reflect on your life's journey, understand past choices, and envision a future aligned with your core values. This guide will help you uncover your unique flow states and ensure your job search is a purposeful journey towards what truly matters to you.

Uploaded 03-10-25

🎯 Learning Objectives
• Understand the foundational questions of the Individual Purpose worksheet.
• Reflect on past choices and current alignment with your future vision.
• Identify and integrate work, pla...

Frontiers of Biomedical Engineering (BENG 100)

Uploaded 18-11-08

Professor Saltzman starts the lecture with an introduction to pharmacokinetics and pharmacodynamics. Professor Saltzman talks about the concept of dose-response. He introduces different routes of drug administration and how they affect drug distribution and bioavailability (i.e., intravenous, oral, and sublingual routes). First-pass drug metabolism by the liver is also identified as an important source of drug degradation. Finally, modeling the body as a well-stirred vessel, Professor Saltzman explains the first-order rate equation: C = (M0/V)*e-kt, that can be used calculate the amount of drug in...

Ever wonder how successful alumni navigate the complex job market? In this lesson, hear from former students who leveraged structured tools and frameworks like detailed spreadsheets, "the hunt" methodology, and "rock" and "triangle" exercises to clarify their priorities, effectively track opportunities, and make intentional career decisions by aligning their skills and desires with ideal roles. They emphasize the power of quantifying subjective factors to integrate both logic and intuition in your job search.

Uploaded 03-10-25

🎯 Learning Objectives
• Learn the benefits of a structured approach to managing your job search process.
• Understand how to effe...

Financial Markets (ECON 252)

Uploaded 19-11-08

Futures markets have expanded far beyond their initial application to farmer's planting and harvest cycles. These markets now allow investors and traders to set prices for a broad spectrum of assets and for a whole term structure stretching into the distant future. Some of these markets are often priced according to simple fair-value formulae, others are not. Futures markets can be in backwardation, where the future price is lower than the present, spot price. They can also be in contango, where the price rises with maturity and is higher...

Are you ready to transform your approach to job chats and interviews? In this lesson, we dive deep into mastering both informal networking conversations and formal job interviews, emphasizing crucial preparation, engaged presence, and diligent follow-up. Learn to refine your pitch, utilize powerful focus techniques like box breathing, practice active listening with methods like 'looping,' navigate cross-cultural communication, and understand the profound impact of timely thank-you notes on your candidacy.

Uploaded 03-10-25

🎯 Learning Objectives
• Master comprehensive preparation strategies for both informal job chats and formal interviews
• Implement active listening techniques, including the 'lo...

🎥 This clip is part of a recurring case study that follows a patient during a routine pain medicine follow-up appointment, where underlying substance use concerns gradually come to light. The scenario highlights how these issues can surface in everyday clinical practice and how providers can respond with empathy and care.

Uploaded 05-08-25

📚 About the Course
This course is designed with a singular goal: to improve the care you provide to your patients with substance use disorders. By delving into a model case performed by actors, seven Yale instructors from various fields provide techniques to scr...

Frontiers of Biomedical Engineering (BENG 100)

Uploaded 18-11-08

Professor Saltzman talks about electrical conductivity in the heart: that is, the generation and propagation of electrical potential in heart cells. He describes the role of ion channels and pumps in transporting sodium, potassium, and calcium ions to create action potential. This propagation of signal from the sinoatrial node through different tissues, which can be replaced by a pacemaker, eventually stimulates contraction of muscle fibers throughout the heart. Next, he describes the electrocardiograph and how each wave trace corresponds to the events caused by depolarization/repolarization of...

Frontiers of Biomedical Engineering (BENG 100)

Uploaded 18-11-08

Professor Saltzman introduces the concepts and applications of biomedical engineering, providing an overview of the course syllabus, reading materials for lecture and labs and grading logistics. Various pictures are shown to highlight the current application of biomedical engineering technologies in daily life (eg. chest x-ray, PET scan, operating room, gene chip, transport). Next, living standards and medical technologies of the past and present are compared to point out the impact of biomedical engineering as well as areas for improvement in the field. Finally, Professor Saltzman draws references...

Frontiers of Biomedical Engineering (BENG 100)

Uploaded 18-11-08

Professor Saltzman discusses the biophysics of the circulatory system. He begins by describing the anatomy of different types of blood vessels, and states the relationship between pressure difference (ΔP) as the driving force for fluid flow (Q) in a tube (i.e., blood vessel) with some resistance R (ΔP = RQ). R can be calculated using if dimensions of the tube (L, r) and fluid viscosity (μ) are known: R = 8μL/πr4. Next, Professor Saltzman traces the blood flow through the circulatory system and explains how the body can regul...

Ever wondered why US healthcare costs are astronomically high, yet quality often lags? In this lesson, we delve into the paradox of healthcare spending in the United States, examining the intricate power dynamics between patients, providers, and payers. We'll explore the "principal agent problem" and the "healthcare hassle map," revealing the complex incentives that drive up costs and impact care coordination. Additionally, we'll consider how social service spending contributes to a broader understanding of total national expenditures.

Uploaded 19-08-25

🎯 Learning Objectives
• Understand the paradox of high healthcare spending and lower quality in the US.