Metabolic Mindset

15 Episodes
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By: Shara Perry

Metabolic Mindset is a science-backed podcast that breaks down metabolic physiology into simple, practical strategies you can actually live by. Hosted by dietitian Shara Perry, each episode cuts through nutrition dogma and teaches you how to fuel, train, and live for better energy, hormones, and long-term health.

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How I Set Calories, Macros, Hydration, and Sodium Targets in a Pro-Metabolic Framework
#15
Yesterday at 5:00 PM

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In this episode of Metabolic Mindset, I break down exactly how I determine calorie, protein, carbohydrate, fat, hydration, and sodium targets using a pro-metabolic framework. We cover the physiology behind energy needs, why I use the Mifflin-St Jeor equation as a starting point, how adaptive thermogenesis influences nutrition planning, and why biofeedback matters just as much as the numbers. You'll also learn how I decide when to adjust calories or macros, why sodium recommendations differ for active individuals, and how to recognize signs that your metabolism is moving in the right...


Understanding Energy Availability and Metabolic Health
#14
07/16/2026

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Many people believe metabolism is simply a matter of calories in versus calories out. But if that's true, why can two people eat the same amount of food, weigh the same, and exercise the same amount, yet experience completely different levels of energy, recovery, hunger, hormone health, and body composition?

In this episode, we're diving into one of the most overlooked concepts in nutrition and metabolism: energy availability. You'll learn why your body doesn't just track calories—it continuously evaluates whether enough energy is available to support essential functions li...


Fruit Isn't the Enemy: Understanding Glucose, Fructose, and Carbohydrate Metabolism Part 2
#13
07/12/2026

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In Part 2 of this series, we follow glucose and fructose to the liver, where their metabolic paths begin to diverge. Learn how the liver processes different carbohydrates, why fructose doesn't automatically turn into body fat, and how glycogen, ATP, fiber, and the food matrix influence your metabolism. We also explore why whole fruit is fundamentally different from sugar-sweetened beverages and why context—not fear—should guide the way we think about carbohydrates.

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Work with me at Nourish (covered by insurance, often $0): https://signup.nourish.com/providers/shar...


Fruit Isn't the Enemy: Understanding Glucose, Fructose, and Carbohydrate Metabolism Part 1
#12
07/07/2026

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In Part 1 of this episode, we begin a deep dive into one of nutrition's most misunderstood topics: carbohydrates. Join me as we explore what carbohydrates actually are, how plants create them through photosynthesis, and what happens the moment you take your first bite. By understanding the science behind glucose, fructose, and digestion, you'll gain the foundation needed to separate nutrition myths from physiology.

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Work with me at Nourish (covered by insurance, often $0): https://signup.nourish.com/providers/shara-perry?referralSource=Nourish+dietitian&referralName=Shara+Perry&utm_source...


A Pro-Metabolic Perspective on Cholesterol and Statins Part 2
#11
06/08/2026

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In Part 2 of the cholesterol series, we're taking a deeper look at why cholesterol labs are often misunderstood and why context matters when evaluating cardiovascular risk.

We'll break down markers like LDL, HDL, triglycerides, ApoB, and ApoA1, discuss the role of inflammation and metabolic health, and explore why two people with similar cholesterol numbers can have very different risk profiles.

We'll also dive into statins—how they work, why they're so heavily debated, and the situations where they may provide meaningful benefit.

Finally, we'll discuss how to im...


A Pro-Metabolic Perspective on Cholesterol and Statins Part 1
#10
05/25/2026

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In Part 1 of this cholesterol series on Metabolic Mindset, I break down what cholesterol actually does in the body, how lipoproteins like LDL and HDL function, and why cholesterol labs are often misunderstood without proper context. I also explore the relationship between inflammation, metabolic dysfunction, and cardiovascular risk — and why a single lab marker rarely tells the full story. In other words, this podcast is an attempt to explain cholesterol in the context of human metabolism.

Topics covered:
• LDL and HDL explained simply
• Cholesterol transport and lipoprotein basics
• What cho...


Metabolism Over Dogma: Why We Both Moved Beyond Low Carb
#9
04/14/2026

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In this episode of Metabolic Mindset, I’m joined by Zane Griggs (@zanegriggsfitness), a long-time personal trainer and host of the Healthy AF Podcast. Zane and I met years ago when we were both deep in the low carb world. Since then, we’ve independently shifted toward a more pro-metabolic, physiology-first approach to nutrition and training.

This conversation is about what actually works for our clients.

We break down why restrictive frameworks like keto or low carb can initially “work,” the psychological pull of diet camps, and what happens when ide...


Taurine: Energy Regulation, Not Stimulation
#8
03/25/2026

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Taurine is one of the most misunderstood nutrients in modern nutrition—often associated with energy drinks, but rarely understood for what it actually does in the body.

In this episode of Metabolic Mindset, I discuss the physiology of taurine and why it plays a critical role in metabolic health. From cardiovascular function and calcium signaling to nervous system regulation, electrolyte balance, and bile production, taurine supports the systems that allow your metabolism to function efficiently.

I also cover where taurine comes from, how it was discovered, key research-backed benefits, an...


Why Overtraining Is Not Helping You Lose Fat
#7
03/06/2026

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In this episode of Metabolic Mindset, Registered Dietitian Shara Perry breaks down why more exercise isn’t always the answer for fat loss. Chronic high-intensity training, under-fueling, and elevated cortisol can actually stall fat loss by breaking down muscle, lowering metabolic rate, and signaling the body to hold onto energy. Shara explains the physiology behind Zone 1 and Zone 2 cardio, how they support mitochondrial health, fat oxidation, and cortisol regulation, and why lower-stress training can be far more effective for sustainable fat loss and muscle retention. If you’ve been work...


Supplements That Support a Pro-Metabolic Framework
#6
02/21/2026

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Most supplements on the market don’t actually support your metabolism. In this episode, I break down which supplements are truly worth your time—covering multivitamins, magnesium, electrolytes, vitamin E, creatine, and glycine—and how they support energy production, thyroid function, fat loss, and overall metabolic health. I also explain which popular supplements, like fish oil and pre/probiotics, may actually interfere with metabolic efficiency.

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Work with me at Nourish (covered by insurance, often $0): https://signup.nourish.com/providers/shara-perry?referralSource=Nourish+dietitian&referralName=Shara+Perry&utm_so...


The Randle Cycle: A Physiology-Based Explanation of Fuel Competition and Energy Efficiency
#5
01/13/2026

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Episode 5 – The Randle Cycle: A Physiology-Based Explanation of Fuel Competition and Energy Efficiency

Why do so many people feel better when they reintroduce carbohydrates — yet can’t explain why?

In this episode of Metabolic Mindset, I break down the Randle Cycle, a core concept in metabolic physiology that explains how fat, protein, and carbohydrates compete for oxidation at the cellular level. You’ll learn why high fat intake can block glucose use, why excess protein without carbohydrates can leave you exhausted, and why carbohydrates are essentia...


The Physiology of Chronic Dieting and Metabolic Adaptation
#4
12/29/2025

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In this episode of Metabolic Mindset, we go beyond calories and macros and dive deep into the physiology of chronic dieting and metabolic adaptation. You’ll learn exactly how prolonged calorie restriction alters thyroid function, leptin signaling, cortisol output, mitochondrial efficiency, muscle metabolism, and fat tissue behavior — and why these adaptations make fat loss increasingly difficult over time. This episode explains, at a cellular and hormonal level, why long-term dieting backfires and what your body is actually responding to when fat loss stalls despite “doing everything right.”

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Why Fat Loss Stalls on “Perfect” Macros: The Physiology
#3
12/18/2025

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In this episode, we break down why fat loss can stall even when calories are controlled and workouts are consistent. You’ll learn how cortisol, thyroid signaling, fuel availability, and recovery determine whether your body burns fat or holds onto it—and why eating less is often not the answer.

Support the show

Work with me at Nourish (covered by insurance, often $0): https://signup.nourish.com/providers/shara-perry?referralSource=Nourish+dietitian&referralName=Shara+Perry&utm_source=Nourish_dietitian&utm_term=Shara_Perry


How to Calculate Calories & Macros in a Pro-Metabolic Framework
#2
12/15/2025

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In this episode of Metabolic Mindset, I break down how to calculate calories and macros using a pro-metabolic framework. You’ll learn how to estimate true maintenance calories, adjust intake for fat loss, maintenance, or muscle gain, and set macros in a way that supports energy, hormone health, and metabolic resilience. I cover why protein anchors the system, carbs fuel the metabolism, fats stay moderate, and how carb tolerance expands as your metabolism heals.

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Work with me at Nourish (covered by insurance, often $0): https://signup.nourish.co...


What Is a Pro-Metabolic Diet?
What Is a Pro-Metabolic Diet? episode artwork
#1
12/03/2025

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What is a pro-metabolic diet, really?
In this episode, Shara breaks down the physiology behind metabolism, why so many mainstream nutrition messages backfire (like “eat less, move more” and “carbs slow your metabolism”), and what it actually means to support the thyroid and mitochondria. You’ll learn the core principles of a pro-metabolic approach, why carbs and minerals matter, and how to start fueling your body without extremes.

Support the show

Work with me at Nourish (covered by insurance, often $0): https://signup.nourish.co...