Dr. Paika Podcast

#GLP1 #Microdosing #Zepbound #Ozempic #WeightLossMaintenance

Microdosing Zepbound & Ozempic: How Low Can You Go and Still Keep the Weight Off?

You hit your goal weight. Now the question is: do you have to stay on this dose forever? More and more people are cutting their GLP-1 dose to a fraction or stretching their shots to every 10 to 14 days, hoping to save money, cut side effects, and keep the weight off.

I'm Dr. Mohammed Paika, a board-certified internal medicine and obesity medicine physician and practicing hospitalist. In this video I break down what the research...

#Ozempic #Mounjaro #GLP1 #Tirzepatide #WeightLossDoctor

Should you split your weekly Ozempic, Wegovy, Mounjaro, or Zepbound shot into two smaller doses? Lots of you have asked me about this in the comments. People split their dose to ease the nausea in the first few days and keep food noise down late in the week. In this video, I explain what the pharmacokinetics predict, what the clinical trials did and didn’t test, and the hidden risks most people never hear about.

As an obesity medicine physician, I walk you through half-life, steady state, peak and trough le...

#FoodNoise #GLP1 #Ozempic #WeightLoss #ObesityMedicine

Can't stop thinking about food, even right after a full meal? That constant chatter has a name: food noise. I explain what it is, why GLP-1 medications like Ozempic, Wegovy, Mounjaro and Zepbound quiet it, and why it often returns when people stop them.

You'll learn the 2 drivers behind it, a simple test to tell real hunger from food noise, and 9 evidence-based strategies to turn it down, with or without medication. Every claim is referenced below.

📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter
Get weekly evidence-based insights on GLP...

#GLP1 #Menopause #Tirzepatide #Semaglutide #WeightLoss

Not losing weight on a GLP-1 after menopause? You’re not imagining it, but your body isn’t broken and the medication hasn’t stopped working. In this video, I’m Dr. Mohammed Paika, board-certified in internal medicine and obesity medicine. I break down what the research really shows about GLP-1s like tirzepatide (Mounjaro, Zepbound) and semaglutide (Ozempic, Wegovy) after menopause.

You’ll learn what menopause does to fat, muscle and metabolism, and how much weight women actually lose at each stage of menopause in the clinical trials. I’ll show you...

#GLP1 #Ozempic #Wegovy #Zepbound #WeightLoss

Why GLP-1 Medications Cause Extreme Fatigue (And How to Fix Low Energy)

Are you exhausted on Ozempic, Wegovy, Mounjaro, or Zepbound? You’re not imagining it. Fatigue is listed in the prescribing information, and it’s one of the most common complaints I see in the comments.

In this video, I’m Dr. Mohammed Paika, an internal medicine and obesity medicine physician. I break down the 4 biological reasons GLP-1 medications can leave you drained: unintentional undereating, quiet dehydration, the drug’s effects on the brain, and nutrient deficiencies like low...

#Ozempic #GLP1 #Semaglutide #AlcoholUseDisorder #WeightLoss

People on Ozempic and Wegovy are reporting a side effect that isn't on the label: they're losing interest in alcohol. Is it real, or just nausea? As an internal medicine and obesity medicine physician, I work this up like an unexplained finding in a hospital patient. We'll look at the patient reports and real-world data, consider every possible explanation, read the newest trials (including the 2026 Lancet trial), and finish with a practical plan.

In this video you'll learn:
Why GLP-1 drugs may turn down cravings, and what "food noise"...

#Retatrutide #GLP3 #WeightLoss #GLP1 #ObesityMedicine

How long does retatrutide actually stay in your system? Retatrutide, the triple-hormone drug people call "GLP-3" or "reta," has a half-life of about 6 days. That one number explains when side effects hit and why the dose has to climb slowly. It also explains why a short pause before surgery may not be enough, and why the drug lingers for about a month after your last shot.

I'm Dr. Mohammed Paika, board-certified in internal medicine and obesity medicine. In this video, I walk you through the 4 clocks retatrutide sets in your...

#GLP1 #WeightLoss #Ozempic #Mounjaro #ObesityMedicine

Not losing weight on a GLP-1? The problem usually isn't you, and it usually isn't the medication either. It's the variables nobody checked.

I'm Dr. Mohammed Paika, a physician board-certified in Internal Medicine and Obesity Medicine. I've spent about 15 years as a hospitalist, and I'm also a certified personal trainer and nutrition coach. In this video, I walk you through 8 evidence-based reasons the scale can stall on semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound), plus a bonus. They range from diabetes and insulin resistance to medications that quietly cause weight...

#Tirzepatide #Mounjaro #Zepbound #GLP1 #WeightLoss

How long does tirzepatide (Mounjaro, Zepbound) actually stay in your system? It's not 5 days. In this video, I explain tirzepatide's half-life using 4 clocks it sets in your body. Those clocks explain when side effects hit and what to do if you miss a dose. They also explain why a 1-week pause before surgery may not be enough, why the birth control rule is 4 weeks, and how long the drug takes to clear after your last shot.

Then we get to the clock that matters most: what happens after you stop...

#Ozempic #GLP1 #Wegovy #EyeHealth #obesitymedicine 

Can Ozempic, Wegovy or Mounjaro make you blind? A viewer asked me this, and it deserves an honest, evidence-based answer. I'm Dr. Mohammed Paika, board-certified in internal medicine and obesity medicine, with more than 15 years as a hospitalist.

In this video I review every major study on GLP-1 medications and NAION, a rare "stroke" of the optic nerve:

The Mass Eye and Ear study that sparked the headlines
The larger studies from Denmark, Norway and the US
The randomized trials

I also cover what t...

#GLP1 #Ozempic #Mounjaro #Wegovy #ObesityMedicine

Most people think GLP-1 medications like Ozempic, Wegovy, Mounjaro and Zepbound are just for weight loss. The research tells a much bigger story. I'm Dr. Mohammed Paika, board-certified in internal medicine and obesity medicine, with more than 15 years as a hospitalist. In this video I count down 12 evidence-graded health benefits of GLP-1 medications beyond the scale, plus a bonus from the newest cancer research.

You'll learn what the major trials show about your heart, liver, kidneys, blood pressure, sleep apnea, inflammation, alcohol cravings, joint pain and blood sugar. I also...

#Mounjaro #Tirzepatide #GLP1 #WeightLoss #obesitymedicine 

Why do two people on the same Mounjaro dose get completely different results? In this video, I break down a study of more than 3,000 people with type 2 diabetes from the SURPASS 1–4 trials. It looked at who is most likely to lose 15% or more of their body weight on tirzepatide (Mounjaro / Zepbound), and why.

You'll learn the 7 factors that predicted the biggest weight loss. Several of them are things you can change, sometimes before your first injection. I also cover what newer research says about Ozempic and Wegovy, why real-world results are...

#GLP1 #Ozempic #Zepbound #Wegovy #weightloss 

Losing weight on Wegovy, Ozempic, Zepbound, or Mounjaro? What you eat while you're on it matters more than most people realize. In this video, board-certified internal medicine and obesity medicine physician Dr. Mohammed Paika breaks down the 3 nutrition gaps that show up again and again in GLP-1 patients — protein, fiber, and fluids — and the 10 foods that address them, backed by real research on muscle preservation, gut health, and the GLP-1 pathway itself.

You'll learn why eating less doesn't automatically mean eating well, what the research says about muscle loss on semag...

#Ozempic #Wegovy #Zepbound #GLP1 #weightlossjourney 

Are you taking Wegovy, Ozempic, or Zepbound and feeling like your results have stalled? In this video, board-certified physician Dr. Mohammed Paika breaks down the 5 mistakes that quietly sabotage GLP-1 results — and exactly what to do instead to keep losing fat, protect your muscle, and avoid unnecessary side effects.

Drawing on his experience as a hospitalist and obesity medicine specialist, Dr. Paika walks through dose titration, nutrition, digestion, and lab work — the pieces most people never get told about.

TIMESTAMPS:
0:00 Intro — Why Your Results Might Be Stalling
0:53...

#GLP1 #Tirzepatide #Semaglutide #WeightLoss #ObesityMedicine

Should you increase your GLP-1 dose — or actually decrease it? Before you touch that pen, run through the 7 checks I use with my own patients (and on myself) to decide whether it's time to go up, hold steady, or come down. This isn't about chasing the highest dose on the label — it's about finding the dose you can tolerate and sustain for the long run.

I'm Dr. Mohammed Paika — internal medicine physician, board-certified in obesity medicine, and a GLP-1 user myself. In this video I walk through dose duration, your real w...

#BPC157 #PeptideTherapy #TendonHealing #RegenerativeMedicine #healthscience 

BPC-157 is everywhere right now — but does the evidence actually justify putting this peptide into your body? In this video, Dr. Mohammed Paika (board-certified internal medicine & obesity medicine) breaks down what BPC-157 actually does, what the animal research shows, what we really know about human safety, and the one theoretical risk that concerns him most as a physician.

BPC-157 is not FDA-approved for any human use.

🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access
Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the comp...

#GLP1 #Semaglutide #Tirzepatide #Inflammation #obesitymedicine 

GLP-1 drugs like semaglutide and tirzepatide don't just lower weight and blood sugar — the research increasingly shows they change inflammation too. In this video, Dr. Mohammed Paika (board-certified internal medicine + obesity medicine, hospitalist) breaks down what CRP actually measures, why chronic inflammation happens, how much of the anti-inflammatory effect is really just weight loss versus a separate biological pathway, and why tirzepatide's second receptor (GIP) may make it different from semaglutide.

🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access
Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-ter...

#Ozempic #Mounjaro #Semaglutide #Tirzepatide #GLP1 #WeightLoss #ObesityMedicine 

If you're on tirzepatide or semaglutide and the scale isn't moving the way you expected, this video is for you. I'm Dr. Mohammed Paika, board-certified in internal medicine and obesity medicine — I've been dealing with these medications in the hospital since they first came out, and I've managed my own weight through diet and training alone for over a decade. In this video I break down what tirzepatide and semaglutide actually are, why they were invented, how they work in your body, the exact dosing timeline, why the shot is onl...

#Peptides #PeptideTherapy #GLP1 #AntiAgingMedicine #bpc157 

Peptides didn't start with a wellness influencer — they started with a dying 14-year-old boy in 1922 and a shot of insulin. Today that same category includes everything from FDA-approved medications to unregulated research chemicals sold online with zero oversight.

In this video I break down over 20 peptides — from BPC-157 and TB-500 to semaglutide, tirzepatide, retatrutide, and the newest FDA regulatory update on compounding access — organized into the three levels of biology they actually work on: cellular energy, tissue repair, and systemic control (your hormones, metabolism, and nervous system).

🎓 Complete GLP-1 Weig...

#Phentermine #WeightLoss #ObesityMedicine #GLP1 #weightlosstips 

The #1 mistake I see patients make on phentermine isn't a dosing error — it's that they stop eating. In this video, Dr. Mohammed Paika (board-certified in Internal Medicine and Obesity Medicine, 20 years as a hospitalist) breaks down exactly why appetite suppression gets confused with starvation, the real physiology of what happens to your metabolism and muscle when you under-eat on phentermine, a patient case from the hospital floor you won't forget, and the protein-first framework to actually keep the weight off long-term.

You'll learn:
– What phentermine actually does in your body...

#Zepbound #Wegovy #Tirzepatide #Semaglutide #glp1 

Zepbound and Wegovy are the two most talked-about weight loss medications right now — but the headlines comparing them skip the context that actually matters. In this video, I break down how tirzepatide (Zepbound) and semaglutide (Wegovy) actually work in your body, compare the real clinical trial data — including the new SURMOUNT-5 head-to-head trial — and walk through the side effects, cost, and questions you need to bring to your physician before choosing between them.

I'm Dr. Mohammed Paika — board-certified in Internal Medicine and Obesity Medicine, and a practicing hospitalist for over 15 years. I...

#Supplements #Longevity #Creatine #Omega3 #glp1medications 

Feeling overwhelmed by the supplement aisle and not sure which five actually move the needle? As a board-certified internal medicine and obesity medicine physician (and a certified personal trainer), I'm cutting through the noise and giving you the only five supplements I actually recommend for longevity, performance, and overall health — with the real dose, the form that's actually absorbed, and the timing that matters, backed by the studies behind every claim.

🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access
Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects...

#Retatrutide #GLP1 #WeightLoss #ObesityMedicine #metabolichealth 

Retatrutide is producing weight loss results we used to only see after bariatric surgery — but the medication is only half the story. In this video, Dr. Mohammed Paika (board-certified in internal medicine and obesity medicine) breaks down the five decisions he'd make before ever taking a first dose: how to find the right dose instead of chasing the highest one, why your heart rate and mood deserve the same attention as the scale, how to protect your muscle while the weight comes off, how to build a supplement plan instead of guessing, and...

#Ozempic #Wegovy #GLP1 #WeightLoss #obesitymedicine 

Nausea, constipation, bloating, gas — if you're on semaglutide (Ozempic or Wegovy), gastrointestinal side effects are the most common thing you'll run into. In this video, I break down exactly why they happen and the specific, evidence-based strategies that actually reduce them: portion sizes, meal timing, which foods make it worse, hydration, injection timing, dose titration, and the red flags that mean it's time to call your doctor — not internet folklore, actual clinical data and two decades of hospital medicine.

🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access
Comprehensive education on GLP-1 medi...

#GLP1 #Ozempic #WeightLossJourney #ObesityMedicine #healthyeating 

Eating less on Ozempic, Wegovy, Mounjaro, or Zepbound doesn't automatically mean your diet is helping you lose fat. In this video, I break down the best foods to eat on a GLP-1 — protein, carbs, healthy fats, and fiber — so you preserve muscle, manage side effects, and get better results from your medication.

I'm Dr. Mohammed Paika, a board-certified internal medicine and obesity medicine physician. Everything in this video comes from the same nutrition science I use with real patients, including two cases straight from my hospital work.

🎓 Complete GLP-1 We...

#Ozempic #Mounjaro #GLP1 #WeightLoss #ObesityMedicine

Ozempic and Mounjaro can be powerful weight-loss tools — but they can also affect your body in ways many people aren't told before starting. In this video, I break down the real risks, the paradox in the trial data, and what to actually watch for.

In this video I walk through why people with type 2 diabetes tend to lose less weight on these medications than people without it, why a meaningful share of the weight lost on GLP-1s can be muscle rather than fat, what the data actually shows about ga...

#Ozempic #Mounjaro #GLP1 #WeightLoss #ObesityMedicine

Some foods can make Ozempic or Mounjaro side effects much worse — even if you're taking the medication exactly as prescribed. In this video, Dr. Mohammed Paika (board-certified in Internal Medicine and Obesity Medicine) breaks down the 5 food categories most likely to cause nausea, reflux, and bloating on a GLP-1 medication — and exactly what to eat instead to support fat loss without fighting your own treatment.

🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access
Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes...

#muscleafter50  #GLP1 #MenOver50Fitness #EvidenceBasedTraining #obesitymedicine 

Building muscle after 50 doesn't work the way it used to — and "just lift heavier" is exactly why most men stay stuck, sore, and stalled. In this video, I break down an evidence-based training framework grounded in NASM's OPT model and backed by ACSM/NSCA resistance-training guidelines for older adults — built to build real muscle while protecting your joints, tendons, and long-term mobility. I also cover why muscle matters even more if you're on a GLP-1 medication, and what the research actually shows about lean mass loss during weight loss.

🎓 Complete...

#Ozempic #GLP1 #BrainHealth #WeightLoss #obesitymedicine 

A physician breaks down what Ozempic really does to your brain — benefits, risks, and what the science actually shows.

🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access
Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost.
https://www.drmohammedpaika.com

📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter
Get weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity.
https://www.drmohammedpaika.com/newsletter

📚 The Weight Equ...

#Ozempic #Mounjaro #GLP1 #WeightLoss #obesitymedicine 

Ozempic and Mounjaro are two of the most powerful tools we've ever had for weight loss and metabolic health — but what you combine them with matters. In this video, Dr. Mohammed Paika, MD (board-certified in Internal Medicine and Obesity Medicine, hospitalist for nearly 20 years) breaks down 10 medications, substances, and habits that can quietly work against your GLP-1 treatment: SGLT2 inhibitors, metformin, cannabis/THC, artificial sweeteners and sugar alcohols, compounded/gray-market GLP-1 products, skipping resistance training, SSRIs, caffeine, diuretics, and stacking multiple GLP-1 medications. You'll learn the actual physiology behind each risk, real war...

#GLP1 #Ozempic #Wegovy #Mounjaro #WeightLoss

Eating less on Ozempic, Wegovy, Mounjaro, or Zepbound doesn't automatically mean you're eating well. In this video, board-certified Internal Medicine and Obesity Medicine physician Dr. Mohammed Paika breaks down the 10 best foods to eat on a GLP-1 medication — and exactly how they support fat loss, muscle preservation, digestion, and better long-term results from your treatment.

You'll learn how GLP-1 and GIP medications actually work in the body, why muscle loss is the risk nobody warns you about, the exact protein targets to hit every day, and the 10 foods — grouped into musc...

#GLP1 #Ozempic #wegovy  #WeightLoss #HighProteinDiet

Eating less on Ozempic, Wegovy, Mounjaro, or Zepbound doesn't automatically mean your diet is helping you lose fat. In this video, hospitalist physician Dr. Mohammed Paika breaks down 15 real grocery-aisle swaps — each evaluated for calories, fat, and carbohydrate quality, not just protein — along with the clinical research on why protein and muscle preservation matter so much while you're on a GLP-1.

0:00 Intro — Why "Eating Less" Isn't Enough on a GLP-1 
0:55 Who I Am (Hospitalist Physician, Not an Influencer) 
2:40 The Patient I Think About 
3:53 Why Protein Isn't Optional on a GLP-1...

#Ozempic #GLP1 #WeightLossJourney #ObesityMedicine #semaglutideforweightloss 

You can be taking Ozempic every week and still stall out — not because the medication stopped working, but because of habits that quietly cancel it out. In this video, Dr. Mohammed Paika (board-certified in Internal Medicine and Obesity Medicine) breaks down the 10 most common mistakes that stall fat loss, cost muscle, and cause GLP-1 side effects — and exactly what to do instead.

📩 Subscribe to our newsletter for weekly evidence-based insights on GLP-1 science, metabolic health, longevity, nutrition, and healthy recipes. You'll also receive a FREE GLP-1 Diet Cookbook, plus access to our c...

#Peptides #GLP1 #WeightLoss #ObesityMedicine #longevity 

Peptides are everywhere online right now, but most videos explain one compound in isolation and skip the actual evidence. In this video, I break down every major peptide people are talking about — repair peptides, growth hormone secretagogues, longevity and immune peptides, hormonal peptides, and the GLP-1 family — with the real human trial data, FDA regulatory status, and honest caveats behind each one. No hype, no fear-mongering — just what the research actually supports.

I'm Dr. Mohammed Paika, a hospitalist physician. I see the downstream effects of unmanaged metabolic and hormonal health every d...

Ozempic #Mounjaro #GLP1 #WeightLoss #ObesityMedicine

Some foods, drinks, medications, and supplements can make Ozempic or Mounjaro harder to tolerate — and a few may raise your risk of more serious side effects. If you're dealing with nausea, reflux, constipation, dehydration, or stomach pain, something else in your routine might be making it worse.

In this video, board-certified Internal Medicine and Obesity Medicine physician Dr. Mohammed Paika breaks down 12 things to be careful with on Ozempic or Mounjaro — and exactly what to do instead. Drawing on 15+ years as a hospitalist and his own experience with GLP-1 therapy, Dr...

#GLP1 #WeightLossJourney #Zepbound #ObesityMedicine #Tirzepatide

You can be taking Zepbound exactly as prescribed and still be making mistakes that quietly stall your results. In this video, I break down the 6 most common mistakes I see — as a board-certified internal medicine and obesity medicine physician — that undermine fat loss, muscle preservation, and long-term success on Zepbound, plus two bonus insights most people never hear from their prescriber.

These aren't theoretical. They're pulled from my own clinical practice, my patients, and my own two personal body transformations.

Want the complete system — deficit strategy, protein targets, traini...

#Metabolism #FatLoss #GLP1 #WeightLossJourney #obesitymedicine 

Think a stalled scale means your metabolism has failed you? It probably hasn't — you're just watching the wrong number. In this video, hospitalist physician and exercise scientist Dr. Mohammed Paika breaks down the 5 real, medically-backed signs your metabolism is actually burning fat, why "fast metabolism" is often a myth, and where a lot of popular advice gets the science dangerously wrong (including the real difference between nutritional ketosis and diabetic ketoacidosis).

Go deeper at drmohammedpaika.com:
→ GLP-1 Masterclass (course + e-book) — the full science of satiety and appetite regulation
→ Free GLP...

#Ozempic #GLP1 #Semaglutide #WeightLossJourney #ObesityMedicine

Most Ozempic and Mounjaro side effects are just uncomfortable — but a few can land you in the ER. In this video, Dr. Mohammed Paika (board-certified internal medicine + obesity medicine physician, 15+ years as a hospitalist) breaks down which GLP-1 side effects are genuinely dangerous, who's at higher risk, and the exact red-flag symptoms you should never wait out.

What's covered:

Why GLP-1 side effects happen (the mechanism in plain terms)
Nausea/vomiting: normal vs. red flag
Dehydration and acute kidney injury
DKA risk for diabetics on GL...

#Longevity #AntiAging #GLP1 #MetabolicHealth #Biohacking

You don't need a complicated longevity routine to start aging better — you need to know which habits actually move the needle. In this video, hospitalist and obesity medicine physician Dr. Mohammed Paika breaks down the evidence-based habits, blood work targets, and training principles that drive real energy, better labs, and a longer, stronger life.

In this video, you'll learn:
- The four free daily habits — grounding, breathwork, morning sunlight, and cold exposure — and the research behind each one
- The truth about cholesterol, triglycerides, and statins (and why one nu...

#GLP1 #Ozempic #Zepbound #WeightLossJourney #ObesityMedicine

Injecting your GLP-1 in the same spot every week and wondering if another site would work better? I break down the actual Eli Lilly pharmacokinetic study comparing abdomen, thigh, and upper arm injections for tirzepatide (Mounjaro/Zepbound) — what the data really shows about absorption, side effects, and appetite suppression, and where the study's small sample size means the "abdomen wins" headline deserves a second look.
By the end, you'll know exactly how much injection site affects your results — and where to actually focus if you want long-term success on GLP-1 therapy.
L...