Dr. Yusaf (PJ) Saleeby shares insights from his practice in 2025 regarding Low Dose Naltrexone (LDN). He discusses patient sensitivity, optimal starting doses, and LDN's efficacy for various conditions including Lyme, cancer, and autoimmune diseases. The conversation also delves into Mast Cell Activation Syndrome (MCAS) and the critical role of informed clinicians in its management.

Low dose naltrexone (LDN) offers potential benefits for various health issues. A Missie from the US shares her personal experience with LDN, highlighting her battles with chronic pain, autoimmune diseases, and a blood disorder. After initial scepticism, she notices significant health improvements, including better sleep and reduced pain. LDN helps reverse organ damage and improve her blood condition, emphasising the need for patience and openness to its benefits.

Pharmacist Dr. James Blackburn shares his journey in pharmacy and the significance of compounding. He discusses low-dose naltrexone (LDN) and its benefits for autoimmune diseases, mental health, and women's health. Insights on compounding practices, quality, and personal experiences with fertility and mental health challenges are highlighted. Dr. Blackburn emphasizes the importance of proper testing and lifestyle's impact on health, addressing the community's need for effective treatments.

Description

Explore the profound impact of music therapy with Professor Lee Anna Rasar on the LDN Radio Show. Discover how adapted songs aid anger management, how harmonica playing enhances respiratory function, and how melodic intonation therapy assists stroke patients. Learn about music's role in sleep induction, dementia care, and Parkinson's gait training, showcasing its neuroscience-based approach.

Book for the Live Zoom webinar, $20 including the recording

With Lee Anna Rasar, Professor of Music Education/Therapy,

titled “Dancing in the Rain: Music to Complement LDN.”

for medical professionals and patients

28...

Low dose naltrexone (LDN) shows promise in treating autoimmune diseases and cancers. Dr. Stephanie Werner shares insights on LDN's effectiveness in managing inflammation and enhancing patient outcomes, particularly in women's health issues like polycystic ovary syndrome and pregnancy challenges. The importance of diet and avoiding inflammatory foods is discussed, along with personal responsibility in healthcare and LDN's potential in managing chronic conditions.

Low-dose naltrexone (LDN) is highlighted as a supportive treatment in oncology, enhancing other therapies rather than acting alone. It helps regulate the immune system, calms microglia, and alleviates symptoms like pain and fatigue. LDN's low toxicity and potential to improve quality of life are emphasized, along with its evolving role in cancer therapies and immune modulation.

Low-dose naltrexone (LDN) is discussed as a treatment for chronic illnesses, focusing on its effectiveness and dosing protocols. Experts highlight the importance of collaboration among healthcare providers and the need for more research and awareness. They address misconceptions, potential insurance coverage, and share patient experiences, emphasizing personalized care in managing chronic conditions. The show invites further inquiries from the audience.

LDN treatment involves specific dosing strategies and patient experiences, particularly for conditions like multiple sclerosis and restless leg syndrome. Timing of medication is crucial, and the discussion highlights the rising prevalence of autism, potential links to environmental toxins, and dietary influences. Families face challenges in managing these conditions, emphasizing the need for ongoing communication between practitioners and patients as understanding of LDN's applications evolves.

Dr. Pamela Smith explores the benefits of low dose naltrexone (LDN) and therapeutic plasma exchange (TPE) for treating toxins and autoimmune diseases. She discusses the rising toxicity in patients and how combining TPE with LDN and nutrients can enhance health outcomes. The importance of personalized treatment plans and the role of inflammation in chronic diseases are highlighted, along with insights on managing medication tolerance and the need for ongoing research.

Dr. Phil Boyle explains how low-dose naltrexone can effectively treat infertility and recurrent miscarriage. He outlines the clinical criteria for its use and shares patient experiences. Maintaining treatment during pregnancy is crucial for better outcomes. The discussion also covers naltrexone's potential benefits for postpartum depression and the significance of endorphin levels in health. Dr. Boyle concludes with a mention of a new publication in restorative reproductive medicine.

Kallos from Napal shared her expereince of LDN and how it helped her get her life back. She has UCTD, Vitiligo and PCOS

Kallos from Nepal shared her inspiring experience with Low-Dose Naltrexone (LDN) and how it has played a crucial role in helping her regain control of her life. Living with conditions such as Undifferentiated Connective Tissue Disease (UCTD), vitiligo, and Polycystic Ovary Syndrome (PCOS) had made daily life challenging for her.

Before starting LDN, Kallos struggled with various symptoms that significantly impacted her quality of life, including fatigue, skin issues, and hormonal imbalances...

Taran from the United States shares her journey with Ehlers-Danlos Syndrome (EDS) and Postural Orthostatic Tachycardia Syndrome (POTS), which began in 2015 when she suddenly passed out at work, becoming bedridden for six months. Despite being very active beforehand, she was left confused and distressed. After researching online and consulting with a cardiologist, Taran received diagnoses for POTS and EDS.

For several years, they underwent a trial-and-error approach to treatment. In September 2024, Taran's mother discovered low-dose naltrexone (LDN) as a potential treatment, leading Taran to a primary care physician specializing in EDS. Nervously, she started LDN at a...

Barb from Canada shares her 26-year journey with fibromyalgia, which began with chronic pain and a lengthy struggle for a diagnosis. Initially, she explored various treatments, including conventional medications like Oxycontin and alternative therapies, but found limited relief.

After learning about Low Dose Naltrexone (LDN) from the fibromyalgia community, she sought a doctor willing to prescribe it. After changing family doctors, Barb encountered a new physician who did not believe in fibromyalgia and refused to prescribe LDN. However, through the LDN Research Trust, she found a supportive doctor who offered remote consultations. Since starting LDN in April...

Deb from Australia shared her journey with rheumatoid arthritis, which she experienced for about four years before receiving a proper diagnosis. Initially, her GP attributed her chronic pain to other issues and suggested topical treatments. A physio at Nambbor General Hospital recognized her symptoms and referred her to a rheumatologist, who confirmed the diagnosis through blood tests and MRIs.

Deb was prescribed methotrexate and folic acid but sought an alternative due to her desire for a healthier lifestyle. She turned to low-dose naltrexone (LDN) upon her integrative GP's recommendation. After starting on LDN, she experienced nausea and...

Pamela from the United States shares her journey with hypermobile Ehlers-Danlos syndrome (hEDS) and mast cell activation syndrome (MCAS), detailing how Low Dose Naltrexone (LDN) transformed her quality of life.

She recalls being frequently ill as a child with chronic sore throats, fevers, and unexplained rashes, treated repeatedly with antibiotics, which left her with long-term side effects. In adulthood, she experienced worsening joint pain, migraines, back and neck problems, and multiple orthopedic challenges, especially after childbirth and through menopause.

After learning about LDN from Ehlers-Danlos support groups and a physiatrist, Pamela started treatment at 0.5 mg...

Jannie, a 74-year-old from Canada, developed Complex Regional Pain Syndrome (CRPS) in 2016 after a severe foot injury and surgery. She began using Low Dose Naltrexone (LDN) after researching its benefits and, with her doctor’s support, became one of the first in her area to try it. LDN significantly reduced her nerve pain and allowed her to live an active life. After needing recent surgery to remove old hardware from her foot, her CRPS briefly returned when she had to stop LDN—but quickly improved once she restarted it. Janie encourages others with chronic pain to research, stay hopeful, and...

Dr. Corey Rice, a former forensic scientist turned functional medicine physician, discussed his journey from solving crimes to treating patients by addressing root causes of illness. He sees adults of all ages, focusing on prevention and early detection through advanced blood work, gut microbiome analysis, autoimmune screening, and cancer liquid biopsies. His treatments begin with gut repair, nutrient repletion, and hormone balancing, sometimes using low-dose naltrexone (LDN) or peptides for immune modulation, regeneration, and anti-aging. He stresses personalized, proactive care and urges both doctors and patients to stay open-minded.

Shanika shares her long journey with autoimmune diseases, beginning with psoriasis in her youth. She highlights the challenges of managing symptoms and the struggle for a proper diagnosis. After years, she is diagnosed with sarcoidosis and finds relief through low dose naltrexone. As an advocate for LDN, she encourages others to explore this treatment and emphasizes the importance of self-advocacy in health management.

Sue from South Africa shared her experience with Ehlers-Danlos syndrome and multiple health challenges. Although she was diagnosed with Ehlers-Danlos syndrome only six years ago, she described being a fragile child with several physical abnormalities that went unnoticed by doctors. These included an indented sternum and a skin issue at the base of her spine. Growing up, she struggled with physical activities and faced bullying due to her abilities, which contributed to her emotional distress.

Her health challenges continued into adolescence, exacerbated by a severe dog bite that led to post-traumatic stress disorder (PTSD), which was not...

Donna, from the United States, shares her journey with multiple sclerosis (MS), which she was diagnosed with in 1992 at the Mayo Clinic in Florida. Initially, she experienced symptoms like fatigue and tingling sensations, but it took time to identify the issue. After trying conventional MS medications and feeling worse, she decided to stop them and manage her condition independently.

Her husband learned about low-dose Naltrexone (LDN) through an investment opportunity for its FDA approval. Skeptical at first, Donna reluctantly started taking LDN and experienced significant improvement in her condition after three months, feeling more energized and motivated...

In this radio interview, pharmacist Dr. Megan Kilkeary shared insights about her extensive experience in compounding, particularly with low-dose naltrexone (LDN). With nearly 20 years of experience in pharmacy, Dr. Kilary emphasized the importance of high-quality compounding, noting that her pharmacy offers LDN in various forms, including tablets, liquids, topical creams, and sublingual options. The most popular dosage is 4.5 mg tablets, which are designed for easy titration. She also highlighted the pharmacy's commitment to potency testing, ensuring that patients receive consistent dosages.

For patients interested in microdosing, especially those looking to taper off opioid therapy or manage addiction...

Today, I'd like to welcome our guest, Yolanda, from the United States. She takes LDN for rheumatoid arthritis and Hashimoto.

Thank you for having me. I had surgery on my foot, thinking it was tendinitis, but it turned out to be rheumatoid arthritis. Soon after, I was diagnosed with Hashimoto. I spent a year researching to find the root cause of my problem, as my mom also has RA. I didn't want to end up like her, unable to use my hands.

I spent a year researching and found that LDN and changes in diet...

Elise from the United States, shared her experiences with mast cell activation syndrome (MCAS), functional neurological disorder (FND), and various health issues. She described dealing with symptoms since childhood, such as severe fatigue, unpredictable energy levels, infections, severe allergic reactions, and bowel issues. Elise also mentioned the psychological impact of her conditions and how she coped with chemical sensitivities, such as avoiding strong smells and educating others about the impact of scented products. She expressed that recently her chemical sensitivity has been improving, and she shared specific memories of how certain perfumes triggered her health issues.

For...

Josie from the United States shared her experience of using LDN for Crohn's disease, asthma, and rheumatoid arthritis. She began using LDN after struggling with Crohn's disease for several years and undergoing multiple surgeries, as traditional medications were not effective in the long term. After researching alternative treatments, she found a specific carbohydrate diet and LDN. Surprisingly, LDN not only alleviated her Crohn's symptoms but also reduced joint pain and respiratory distress from asthma. She started taking LDN in 2007 and initially experienced euphoria and deep sleep as side effects. Before using LDN, Josie suffered from gastrointestinal pain, cramping, diarrhea...

I'd like to share the story of our guest, Mark from Australia, who will be talking to us about chronic pain and LDN. Mark's pain journey began about 10 years ago after a snowboarding accident which led to slipped discs. Over the past 2 and a half years, he has undergone multiple treatments including heavy medications and surgeries. However, about 6 months ago, he was introduced to LDN which has significantly improved his quality of life. Before LDN, Mark's pain levels were consistently high, impacting his daily activities and sleep. Now, thanks to LDN, his pain levels have decreased, and he's able...

Dermot from Ireland started experiencing chronic fatigue syndrome symptoms after undergoing cancer treatment in 2018. His health declined significantly after a potential COVID-19 infection in early 2020, leading to ongoing health challenges such as nausea, fatigue, and difficulty breathing. Despite undergoing various tests and consultations, the exact cause of their symptoms remained unclear. After experiencing a brief improvement in 2022, they identified chronic fatigue mixed with irritable bowel syndrome as potential causes of their ongoing health issues and are exploring treatment options including LDN which has helpped enormously.

I'm Kerry from the US, I developed symptoms of lupus and fibromyalgia when I was 15. I struggled with fatigue and missed a lot of school. I was initially diagnosed with rheumatoid arthritis, but it was later changed to lupus. The treatments I received included gold salts, aspirin therapy, and eventually steroids. The steroids helped, but I experienced severe side effects, such as significant weight gain and swelling. I've been taking ibuprofen and Plaquenil, but they have their own risks and side effects. I also experienced leg pains that seemed unrelated to lupus, leading to a fibromyalgia diagnosis.

...

Dr. Maria Torsiello, a pharmacist from Richmond, Virginia, was interviewed about her work at a compounding pharmacy.

She discusses her journey to becoming a pharmacist and her passion for science and helping people. Dr. Torsiello also provides insights into the compounding pharmacy where she works, describing the nonsterile compounding services they offer.

The conversation delves into the compounding of LDN (low-dose naltrexone) and its potential applications for various conditions, including in children and for sublingual administration. Additionally, there is mention of an upcoming conference where Dr. Torsiello's pharmacy could benefit from learning...

Today, Cheryl from Australia, shares her story of LDN for long Covid that resulted in fibromyalgia and chronic fatigue syndrome.

I got COVID in August 2021, which resulted in a severe infection with double pneumonia and landed me in the hospital for a month. When I arrived home from the hospital a month later, that was exactly when long Covid began. However, back then, it was still relatively new, and nobody knew much about it. It is actually very common for long Covid to set in a month after having Covid. As you mentioned, I've since been diagnosed...

Jenn from Canada shared her experience with mast cell activation syndrome (MCAS) and Ehlers-Danlos syndrome (EDS). She described experiencing symptoms of disautonomia and dislocations from a young age. Her health challenges worsened during her teen years with symptoms such as mold exposure, recurrent hospitalizations for mystery illnesses, and autoimmune-related issues. It wasn't until two years ago that she was diagnosed with MCAS after discovering hidden mold in her home. After consulting with an allergist and starting on a personalized treatment cocktail, including low-dose naltrexone (LDN), she noticed improvements in her chronic headaches, sleep, and other symptoms. The LDN helped...

Sunita from the United States who takes LDN for fibromyalgia depression dry eye and dry mouth, her journey start end of 2013 living in a house with mold. She has Thyroid issues, Sjogrn's syndrome and LDN changed her life.

Dani from the US has undergone a gruelling and arduous health journey. Recently, she uncovered a tumor on her liver, prompting a series of tests that ultimately led to the diagnosis of mast cell activation syndrome (MCAS). Throughout her life, she has grappled with issues such as dislocating limbs, vertigo, gut problems, erratic sleep, rashes, and mental health challenges. By eliminating gluten and dairy from her diet, she has found some relief. It's evident that she has endured a great deal and has consulted numerous specialists before finally receiving her diagnosis.

ade shared her story on the LDN radio show, discussing her health struggles, including fatigue, gut issues, severe nausea, and neurological symptoms. She also mentioned being diagnosed with long COVID. Despite seeking help from various doctors and specialists, she continued to suffer. After nine months of struggling, a naturopath put her on LDN, which significantly improved her nausea. Although she started experiencing widespread pain and other symptoms later on, LDN proved to be a game changer for her. She expressed hope in figuring out her health issues with time.

Lindsay shared her health journey. She discussed her experience of being diagnosed with Postural Orthostatic Tachycardia Syndrome (POTS), Ehlers-Danlos Syndrome (EDS), and Mast Cell Activation Syndrome (MCAS). She described first noticing symptoms in her early 30s, leading to her POTS diagnosis in 2017 after fainting during a tilt table test. Lindsay also shared her battle with breast cancer, undergoing treatment, and successfully overcoming the challenges. In 2022, she encountered a frightening episode of rapid heart rate, trembling, and other distressing symptoms, prompting her to seek help from a functional gastroenterologist. Lindsay explained her ongoing struggle with gut issues, constipation, a dairy...

Jade from South Africa talks about dealing with Hashimoto's

and her journey with Low Dose Naltrexone (LDN). Jade was diagnosed with

Hashimoto's in 2010, but she only discovered LDN in 2019 after stumbling upon

it in a Hashimoto's Facebook group. She consulted with a functional doctor in

South Africa who prescribed LDN for her.

Before receiving her Hashimoto's diagnosis, Jade experienced

severe hair loss, which prompted her to seek medical attention. Although she

didn't exhibit typical symptoms such as weight gain, she suffered from fatigue,

...

Makiah from the US, shared her health journey, which began in childhood but became more noticeable after her second pregnancy. She experienced fatigue, gut issues, and abnormal postpartum recovery. After her third pregnancy, which was difficult and ended tragically with the loss of her son, she faced persistent health challenges, including bleeding, weight fluctuations, and fatigue. Seeking answers, she was diagnosed with endometriosis, adenomyosis, insulin-resistant PCOS, adrenal insufficiency, and gut dysbiosis. Despite following treatment protocols, she still experienced fatigue and food reactions, eventually discovering a potential link to Ehlers-Danlos syndrome (EDS) and mast cell activation syndrome.

This interview offers a detailed and introspective look into Mandi's journey with LDN, thoracic outlet syndrome, MCAS, POTS and EDS. Through her account, she delves into the intricacies of her diagnosis, the complexities of surgical interventions, and the impact of her children's medical challenges on her own health journey. Additionally, Mandi provides an in-depth exploration of how LDN has played a pivotal role in managing these intricate conditions, offering a comprehensive and informative perspective.

Veronique from Canada shared her experience of living with multiple health conditions, including MCAS, EDS, POTS, ADHD, and autism. She faced challenges with late diagnoses, frequent falls, injuries, dislocations, and gaslighting by medical professionals. Her typical day involved extreme fatigue, cognitive difficulties, chronic pain, digestive issues, and the struggle to function normally. She also experienced vertigo, fluctuating blood pressure, and difficulty eating. Veronique's story highlights the physical, emotional, and mental impact of her conditions and the challenges she faced in managing her daily life.

Cindy, a guest on the LDN radio show, shared her remarkable health journey. She described experiencing hypermobility from a very young age and enduring a multitude of health challenges, including menstrual issues, pots, and food allergies. Her difficult pregnancies and the revelation of her genetic predisposition to certain conditions shed light on the intricate genetic component of her health issues. Through her story, she emphasized the complexities of managing multiple health conditions and underscored the significance of comprehending the genetic factors at play in her health struggles.

Today, we had the opportunity to hear Debbie's Chronic Pain story, a patient from the United States who is using  Low Dose Naltrexone (LDN) for chronic regional pain syndrome (CRPS).

Debbie recounted going back to when she was seven years old and suffered a knee injury, leading to a series of medical interventions. Despite numerous surgical procedures, the chronic pain persisted, and she endured multiple operations without finding relief.

Eventually, Debbie was diagnosed with CRPS, marking the beginning of her battle with persistent pain. In her treatment process, Debbie started LDN with an initial dose o...