Hypertrophy Past and Present
A deep dive into the science of muscle growth. Hosted by Chris Beardsley and Jake Doleschal, this podcast explores hypertrophy training through the lens of pre-steroid era bodybuilding and modern muscle physiology.
045 Training a muscle 2x per week - Full Body vs Upper/Lower
In this episode of Hypertrophy Past & Present, Jake and Chris break down an often misunderstood programming question: how does full body training twice per week compare to an upper/lower split performed four times per week? The episode begins with a deep dive into a late 1960s program from Chuck Sipes, before discussing the key differences between full body and upper/lower when frequency is equated.
Key topics include:
• Why full body twice per week is one of the most underrated training splits
• A breakdown of a classic Chuck Sipes program
• The difference between within...
044 How to write a fat loss training program
In this episode of Hypertrophy Past & Present, Jake and Chris break down how to structure a training program during a dieting phase. The episode begins with a deep dive into how Silver Era bodybuilders approached “definition” training, including a reconstructed Reg Park program, before moving into the physiological realities of training in a calorie deficit.
Key topics include:
• Why Silver Era bodybuilders didn’t drastically change their training when dieting
 • Reg Park’s “definition” routine
 • Why exercise variety may help prevent atrophy during a calorie deficit
 • Why high volume and excessive fatigue are counterproductive w...
043 How to design the ultimate glute program
In this episode of Hypertrophy Past & Present, Jake and Chris discuss how to build the biggest glutes possible. The episode begins with a rare Silver Era lower-body routine from a female 1940s strength athlete Abby “Pudgy” Stockton, before breaking down the most effective modern exercises for glute development.
Key topics include:
 • Abby Stockton’s 1940s lower body routine
 • The difference between upper and lower regions of the gluteus maximus
 • Why seated hip abduction is one of the best exercises for the upper glutes
 • Hip thrust vs glute bridge
 • Why squats and leg presses can still...
042 How to build the biggest arms possible
In this episode of Hypertrophy Past & Present, Jake and Chris discuss how to build the biggest arms possible. The episode begins with a Golden Era arm routine from Chuck Sipes, before assessing the best exercises for both minimalist and maximalist arm programming.
Key topics include:
Chuck Sipes’ Golden Era arm routine (biceps and triceps)How different exercises bias the brachialis, brachioradialis, and biceps brachiiWhy chin-ups are not actually a great biceps exerciseVoluntary activation deficits and why exercise variety mattersThe difference between minimalist and maximalist programmingWhy arm muscles fatigue and damage more easily than most people think041 New study shows twice as much volume doesn't cause extra muscle growth
In this episode of Hypertrophy Past & Present, Jake and Chris dive into whether more volume is always better. The episode opens in the late Silver Era with Sergio Oliva’s high-volume split, then pivots into a brand-new study that compares “high” vs “super high” volumes in trained lifters.Â
Key topics include:
Sergio Oliva’s late-Silver Era routine New study 18 vs ~32 sets per weekWhy “more volume” didn’t produce more hypertrophyDamage as “resource drain” vs damage as fatigueNo fascicle length changes in trained lifters (and what that implies about sarcomerogenesis)Practical programming tip, reframing “rest days” as repair days040 This new study will change how you think about fatigue
In this episode of Hypertrophy Past & Present, Jake and Chris unpack a new hypertrophy study that illustrates how fatigue doesn’t just make training harder but can directly reduce the hypertrophic stimulus by lowering single-fibre mechanical tension. The episode opens in the Silver Era again with Henry Paschal’s 1950 “busy person” program then pivots into the core discussion: why fatigue mechanisms (CNS and calcium-ion related) dampen muscle growth, and what this implies for exercise order, rep ranges, and advanced training methods.Â
Key topics include:
Henry Paschal’s 1950 routineA new “repetition duration” studyHow CNS fatigue and calcium-ion fatigue both se...039 How to instantly increase your strength (through motivational techniques)
In this episode of Hypertrophy Past & Present, Jake and Chris break down how you can become stronger immediately - not by changing your program, but by changing your motivation. The conversation starts in the Silver Era again, comparing Clarence Ross’ 1949/50 routine to his 1952 “favourite routine”, and why the small adjustments he made make physiological sense. From there, Chris connects motivation to motor unit recruitment through Marcora’s Psychobiological Model of Fatigue.
Key topics include:
Clarence Ross’ 1949/50 vs 1952 routine: what changed and why it mattersHow motivation can increase strength right now via higher voluntary activation / recruitmentPractical ways to boost m...038 Periodisation for hypertrophy is pointless (unless you do this)
In this episode of Hypertrophy Past & Present, Jake and Chris unpack periodisation for hypertrophy, including what it actually is (and isn’t), why most “periodised” bodybuilding programs end up adding complexity without adding results, and which variables you can change over time without accidentally driving atrophy or accumulating a fatigue debt. The episode opens in 1952 with Clarence Ross’ pre-steroid full-body AAA “favourite routine”. From there, Jake and Chris break down the three main variables people try to periodise in hypertrophy training: volume, rep range, and exercise selection.
Key topics include:
-Why Clarence Ross’ 1952 full-body plan is a great 'non p...
037 How to grow muscle only training once per week
In this episode of Hypertrophy Past & Present, Jake and Chris tackle a surprisingly common question: what if you can only train once per week? Beginning with an early-1960s two-way split from John McCallum to discuss exercise sequencing, why multi-joint lifts paired with single-joint “finishers” can preserve recruitment better than simply adding more straight sets, and what older routines got right (and missed) due to equipment constraints. The episode then breaks down why once-weekly training is uniquely difficult for hypertrophy, how maintenance literature informs minimum set targets, and what a realistic once-per-week template actually looks like.
Key topi...
036 Dorian Yates, Maximalist Programming, and Neuromechanical Matching
In this episode of Hypertrophy Past & Present, Jake and Chris analyse one of Dorian Yates’ early pre-Olympia training programs, breaking down the structure of his torso-limbs split and the intuitive exercise sequencing.
From there, the conversation expands into a deeper discussion on exercise selection within a workout, why multiple exercises for the same muscle in a single session can produce a superior stimulus to rotating single exercises across sessions, and how this ties into neuromechanical matching and motor unit recruitment. The episode finishes with Chris addressing common criticisms of neuromechanical matching, explaining why alternative theories fail to ex...
035 Which advanced methods work? Cluster sets, drop sets, pre-fatigue, and more!
In this episode of Hypertrophy Past & Present, Jake and Chris break down the resurgence of “advanced” training techniques like clusters, supersets, giant sets, pre-exhaust, drop sets, and rest-pause. Using an early Chuck Sipes “heavy-light” split as an example of early bodybuilding plans that incorporated some advanced methods, the conversation then explains why most of these methods are at best time-saving rather than stimulus enhancing.
The episode finishes with Jake and Chris discussing a “physiological drop set” concept, which may increase recruitment levels without suffering from the same fatigue problems as other advanced methods.Â
Key topics include:
...
034 Voluntary activation deficit: exercise selection, muscle mass, and form
In this episode of Hypertrophy Past & Present, Jake and Chris analyse a Golden Era training plan attributed to Larry Scott and Vince Gironda, using it as a lens to explore how hypertrophy programming evolved after the introduction of anabolic drugs. From there, the conversation pivots into a deeper examination of modern debates around exercise selection, “redundant” movements, single vs multi joint training, and the current discussions around form. Chris introduces voluntary activation deficits as the unifying physiological principle.
Key topics include:
Larry Scott’s Golden Era full-body routineThe limits of motor unit recruitment and voluntary activation defici...033 How to write programs that satisfy client expectations AND really work
In this episode of Hypertrophy Past & Present, Jake and Chris kick off 2026 with a Part 2 follow-up aimed at coaches. Last episode was about the mistakes lifters make when they return to the gym, this week is about the mistakes coaches make when they design and deliver programs to clients. The conversation starts with Bob Hoffman’s time-efficient “working man” full-body routine and why the plan made sense for its context, while also pointing out where it falls short. From there, the episode pivots into the two main problems coaches have to solve today: time constraints and novelty expectations, plus practi...
032 Common training mistakes to avoid in 2026
In this episode of Hypertrophy Past & Present, Jake and Chris take a practical, end-of-year look at the most common mistakes people make when returning to the gym, whether they’re starting fresh in January or jumping back in after time off. Using a pre-steroid era full-body routine attributed to George Eiferman the discussion highlights what earlier bodybuilders consistently got right.
From there, the conversation expands into current gym programming trends, including unstable exercise selection, cardio-driven exercises, excercise novelty, poor progress tracking, and misguided injury-prevention strategies.Â
Key topics include:
-George Eiferman's "favourite" 1952 full-body routine
<...031 How steroids and TRT increase injury risk (and how modifying your training might help)
In this episode of Hypertrophy Past & Present, Jake and Chris break down Mike Mentzer’s “most productive” routine and use it as a turning point to discuss how training trends shifted across the Golden Era. From there, the conversation shifts to how anabolic steroid use increases tendon and ligament rupture risk and whether the rise of higher-rep training, shorter rest periods, machines, slower eccentrics, and lower frequency in the post-steroid bodybuilding era might partly reflect an unconscious attempt to manage connective tissue risk as drug use escalated.
Key topics include:
Mike Mentzer’s two-way split (with rest day...030 Everyone's wrong about muscle activation + how to compare hypertrophy programs (WNS)
In this episode of Hypertrophy Past & Present, Jake and Chris shift from the Silver Era into the early anabolic era by analysing a Golden Era training plan from Ken Waller. Using Waller’s 1975 routine as a case study, they explore how bodybuilding training changed as anabolic use became more common. The discussion then transitions into a deep dive on the Weekly Net Stimulus model and why hypertrophy must be understood at the muscle fibre level.
Key topics include:
Ken Waller’s 1975 Golden Era training split and how it contrasts with Silver Era full-body plansWhy large volumes can...029 Elevated MPS ≠muscle growth
In this episode of Hypertrophy Past & Present, Jake and Chris revisit the Silver Era through one of the most iconic Silver Era bodybuilders, John Grimek, and his bulking plan. They then discuss what muscle protein synthesis (MPS) and muscle protein breakdown (MPB) really mean, dismantling the idea that “elevated MPS = muscle growth”.Â
Key topics include:
-John Grimek’s full-body gaining routine and the practical logic of Silver Era plans
-MPS vs MPB and net protein balance
-Why you can’t assume elevated MPS always reflects hypertrophy or protection from atrophy<...
028 How does dieting affect hypertrophy?
In this episode of Hypertrophy Past & Present, Jake and Chris go back to 1945 and break down Clancy Ross’ pre-contest “definition” routine to show how Silver Era lifters tried to get lean using their gym programming. From there they pivot into dieting and how caloric restriction, stress, glycogen, and glucocorticoids actually affect muscle protein synthesis and muscle protein breakdown.Â
Key topics include:
Clancy Ross’ 1945 full-body “reducing routine” and why even this questionable plan still beats most modern fat-loss programsA muscle-physiology model of dieting: suppressed MPS and when deficits become a stressor that ramps up muscle protein breakdownWhy anabolics (an...027 Are 4 reps optimal?! New study: stimulating reps vs volume load
In this episode of Hypertrophy: Past & Present, Jake and Chris use a 1967 Bill Pearl program to jump from the silver era into the early steroid era, showing how training volume exploded once anabolics entered the picture. They contrast Bill Pearl’s high-volume, six-day split and contrast it with his earlier natural-era programming, before diving into a new study comparing heavy versus light loads in trained lifters and what it really means for stimulating reps, volume load, and rep range choices.
Key topics include:
Bill Pearl’s 1967 high-volume, six-day split and how it differs from his natural-era rout...026 How does insufficient sleep affect hypertrophy / atrophy?
In this episode of Hypertrophy: Past & Present, Jake and Chris dive into a Bill Pearl full-body routine, using it as a bridge between the pre-steroid silver era and the early anabolic era. From there, they shift into part two of their sleep series, unpacking how sleep loss influences muscle atrophy and recovery in natural lifters.
Key topics include:
Bill Pearl’s 1957 full-body planThe difference between immobilisation/diet-induced atrophy vs stress/sleep-loss-induced atrophy Practical programming changes when sleep is poorWhy dieting hard while sleep-deprived is a recipe for muscle loss in naturals, and why enhanced lifters often don...025 How does insufficient sleep affect training?
In this episode of Hypertrophy: Past & Present, Jake and Chris break down Bob Hoffman’s basic athletic program through a modern physiology lens and unpack how insufficient sleep impacts training performance.
Key topics include:
Bob Hoffman’s silver era full-body athlete hypertrophy programSleep deprivation vs restriction vs cumulative sleep debtHow insufficient sleep affects hypertrophy training performancePractical strategies for adjusting a workout after poor sleep024 Training, hypertrophy, and recovery for older people
In this episode of Hypertrophy: Past & Present, Jake and Chris discuss Silver-Era author Peary Rader’s “training as you get older” guidelines and dive into how to construct a modern, physiology-led template for older lifters.
Key topics include:
Why recovery, not “low stimulus sensitivity” likely limits muscle growth in older liftersIntra-session fatigue control in older liftersProgramming for older lifters: volume, RIR, exercise selection, frequencyIsometrics for older lifters023 Fatigue accumulation and what to do about it.
In this episode of Hypertrophy: Past and Present, Jake and Chris unpack a Silver-Era routine passed from 1950 Mr America John Farbotnik to Gene Mozee at a time where high volume plans were taking over bodybuilding. From there they go deep into accumulating fatigue, how excitation–contraction coupling failure, muscle damage, and supraspinal CNS fatigue interact across sessions, why exercise novelty and split design can make this worse, and how to calculate and clear your “fatigue debt” without losing muscle.
Key topics include:
John Farbotnik full body routineBack-off sets: why back-offs add soreness but little stimulusThe three post-w...022 How intra-workout carbohydrates reduce supraspinal CNS fatigue
In this episode of Hypertrophy: Past and Present, Jake and Chris unpack Steve Reeves’ 1947 pre-competition full-body routine, then dive into why the Silver-Era were such advocates of orange juice + honey during training. We assess the building research on carbohydrate mouth-rinsing, what this tells us about supraspinal CNS fatigue, and how the performance increase from carbohydrate mouth-rinsing differs from the performance increase from creatine supplementation.Â
Key topics include:
Steve Reeves’ 1947 pre-comp full-body planWhat carbohydrate mouth-rinsing is doing and intra-workout carbohydratesWhy everyone experiences supraspinal CNS fatigue during strength training and what you can do about itWhy creatine adds reps...021 Why Counting “Half Sets” for Secondary Muscles Doesn't Make Sense
In this episode of Hypertrophy: Past and Present, Jake and Chris break down Dick DuBois’ 1954 full-body routine (and we finally have some pull-ups!). They then tackle the “half-set” myth, why counting half sets for secondary muscles make any sense and how to adjust multi joint exercises to bias growth in a particular muscle.
Key topics include:
• Dick DuBois’ 1954 full-body plan
• The “Half-Set” problemÂ
• Damage in secondary muscles
• Using multi joint exercises in beginner vs advanced lifters
020 How to program a muscle specialisation phase
In this episode of Hypertrophy: Past and Present, Jake and Chris use Peary Rader’s leg routine to outline a practical, physiology-led blueprint for muscle specialisation.
Key topics include:
Peary Rader’s pre-steroid era leg routine (and the changes we would make today)A framework for designing a muscle specialisation phase for any muscleWhen to specialise and how to integrate it into your main plan without losing your progressWriting programs using science-based (mechanisms) vs evidence-based (outcomes)019 Cluster Sets – How they work and how to use them
In this episode of Hypertrophy: Past and Present, Jake and Chris start by discussing one of the most widely used methods of the Silver Era; the 20 rep squat. They then dive into the physiology of cluster sets: what they are, how they differ from rest-pause and drop sets, and how cluster sets can be programmed to offer benefits over traditional straight sets.Â
Key topics include:
• Reg Park chest specialisation phase (including the classic 20-rep breathing squat method)
• Fatigue mechanisms in clusters explained: metabolite, calcium-ion, spinal, and supraspinal fatigue
• Clusters vs rest...
018 Pauses, Stretching, and Partials
In this episode of Hypertrophy: Past and Present, Jake and Chris unpack Reg Park’s calf-specialisation phase before discussing the physiology of pauses: when they work, when they don’t, and how they compare to partial reps.
Key topics include:
• Reg Park’s 1952 calf-specialisation program
• Straight-leg vs bent-leg calf work and how they bias gastroc vs soleus
• The physiology of pause fatigue: metabolite vs calcium-related mechanisms
• Why static “passive” stretching isn’t the same as active pause contractions
• How to assess whether a given exercise will actually benefit from pauses
017 Exercise Selection - How to pick the exercises needed to maximally develop a muscle
In this episode of Hypertrophy: Past and Present, Jake and Chris discuss Sig Klein’s extensive routine and use it as a springboard to tackle one of the biggest programming questions: how much exercise variety do you really need for maximal growth?
Key topics include:
How neuromechanical matching explains which motor units get recruited firstVoluntary activation deficits - why bigger muscles and bigger lifts mean some motor units aren't recruitedHow to use unilateral work to meaningfully increase recruitmentWhy some muscles require greater exercise variation than others016 Training Splits - Why upper/lower, torso/limbs, push/pull, and other split routines face the same problem
In this episode of Hypertrophy: Past and Present, Jake and Chris revisit Joe Weider’s early 1940 full-body program before breaking down the central problem that all split routines face: supraspinal CNS fatigue.
Key topics include:
• How calcium-ion–related fatigue and inflammation create global CNS fatigue
• Why back-to-back training days reduce recruitment, even for unrelated muscles
• Why full-body AAA and AB formats avoid these issues
015 Training Frequency - Why 3x per week beats 2x even if MYOPS is still elevated
In this episode of Hypertrophy: Past and Present, Jake and Chris explore Sig Klein’s early A/B full body routine from the pre-steroid bodybuilding era before examining the claim that elevated myofibrillar protein synthesis blunts the effectiveness of subsequent workouts.
Key topics include:
Sig Klein’s beginner routine The difference between myofibrillar protein synthesis and hypertrophy stimulusWhat comparing one vs three set studies shows us about elevated synthesis timelinesWhy any overlap effect is small (and irrelevant for single-set workouts)Why the weekly net stimulus still favours three times per week over two times per week train014 Training Frequency - What the long-term studies actually show
In this episode of Hypertrophy: Past and Present, Jake and Chris explore the lesser-known silver-era bodybuilder Floyd Page’s 1952 full-body routine before unpacking the topic of training frequency, long-term training studies, and physiological models.
Key topics include:
Floyd Page’s 1952 “favourite routine” and its historical contextThe non-linear dose-response of sets and why frequency changes the outcomePhysiological models vs. long-term training study dataWhat the Currier (2023) network meta-analysis really showsWhy three times per week consistently beats once per week, and where two times fits inThe role of models in filling research gaps and guiding practical programmingHow to navigate conflict...013 Neuromechanical Matching: Everything you need to know (but few do)
In this episode of Hypertrophy: Past and Present, Jake Doleschal and Chris Beardsley unpack one of Peary Rader’s Silver Era “advanced beginner” routines, before a deep dive into the principle of Neuromechanical Matching.
Key topics include:
What Rader’s “advanced beginner” (intermediate) plan looked likeA deep dive into the neuromechanical matching principleCommon misconceptions and critiques of NMMHow it interacts with the size principle and fatiguePractical implications for programming012 How to build muscle with isometric training
In this episode of Hypertrophy: Past and Present, Jake Doleschal and Chris Beardsley break down an isometric method from bodybuilding legend and first Mr Universe, John Grimek. They explore how maximal-effort isometrics can stimulate muscle growth and the key differences between overcoming and yielding isometrics.
Key topics include:
How isometrics produce hypertrophyThe role of joint angle specificityYielding isometrics versus overcoming isometrics Practical ways to program isometrics011 Why the idea that a single exercise can train the whole muscle and “bias” a region is false
In this episode of Hypertrophy: Past and Present, Jake Doleschal and Chris Beardsley dive into a 1955 arm specialization routine from Peary Rader and use it as a launchpad to challenge one of the most common misconceptions in hypertrophy programming today.
They explore whether exercises can “bias” specific muscle regions, and what the implications are for hypertrophy programming.
Key topics include:
What it really means to “bias” a region of a muscleWhy the idea that a single exercise can train the whole muscle and “bias” a region is falseThe critical role of voluntary activation deficits and neuromec...010 Warming up - what does it really achieve?
In this episode of Hypertrophy: Past and Present, Jake Doleschal and Chris Beardsley unpack the very first York Barbell course, discussing its warm-up approach and how it compares to other silver era routines.
The second half of the episode zooms out to explore warm-ups more broadly, what they actually do (and don’t do), whether they affect hypertrophy, and why most warm-up advice might be misguided.
Key topics:
The three physiological effects of warming up: temperature, PAP, and PAPEWhy most common warm-up routines may do nothing for hypertrophy or injury preventionHow to structure warm-ups th...009 Work capacity - what it is and how to improve it
In this episode of Hypertrophy: Past and Present, Jake Doleschal and Chris Beardsley break down a pre-steroid bulking routine from Alan Stephen, an underrated Silver Era bodybuilder who trained with a pretty unique method. They explore how this high volume, low rep program makes sense with the stimulating reps model, and use it as a springboard to unpack one of the most misunderstood training concepts: work capacity.
Key Topics:
• The three definitions of “work capacity” and which one actually matters
• Why volume doesn’t improve your ability to do more work
• How cardiovascular endurance (and not high...
008 Training Frequency - what to consider if you want to train every day
In this episode of Hypertrophy: Past and Present, Jake Doleschal and Chris Beardsley explore whether full body training can be done every day, and what that really looks like. Drawing inspiration from Bronze Era strongman George Hackenschmidt, they unpack creative strategies for making high frequency training work.
Key Topics:
How training every day differs from traditional 3x per week programmingHow MYOPS behaves and whether it must return to baseline before training againWhat programming variables to consider when training full body daily007 Do all training programs maximise hypertrophy eventually?
In this episode of Hypertrophy: Past and Present, Jake Doleschal and Chris Beardsley return to Reg Park, but this time explore one of his most advanced programs. They compare this higher volume plan to Park’s earlier abbreviated routine before exploring whether all training programs eventually lead to the same outcome, and which variables actually determine your muscular potential.
Key Topics:
How Reg Park’s exercise selection evolved from bulk to shapeThe physiology behind fibre-specific muscle damageWhy exercise selection and frequency determine your end resultWhat volume actually does (and doesn’t) achieve when it comes to muscle...006 Strength - the mechanisms that increase strength, and why hypertrophy must make us stronger
In this episode of Hypertrophy: Past and Present, Jake Doleschal and Chris Beardsley discuss one of the strongest bodybuilders of the Silver Era, and the third man to ever bench 500 pounds, Marvin Eder's training routine.Â
The second half of the episode takes a deep dive into the mechanisms of strength, why strength isn’t a single adaptation, and why hypertrophy does contribute to strength.
Key Topics:
The alignment between old-school programming and recoverability dataWhy strength isn’t one thingThe 6 mechanisms of strength gains (and how they interact)What lateral force transmission is