GiveWell Conversations

GiveWell works to continually improve our research so we can make better grant decisions and direct donations where we believe they can do the most good. GiveWell’s Cross-Cutting research subteam is an important part of that effort—it investigates the impact of the programs we fund, works to resolve our largest uncertainties, and aims to improve our research. As GiveWell’s grantmaking grows, the Cross-Cutting subteam is strengthening our data collection and analysis to support that growth. 

In this episode, GiveWell co-founder and CEO Elie Hassenfeld speaks with Program Director Alex Cohen, who leads the Cross-Cutting subteam...

GiveWell, with co-funding from Coefficient Giving, recently made our largest grant to date: $276 million to the Against Malaria Foundation (AMF) to support the procurement and distribution of 92 million nets in the Democratic Republic of the Congo (DRC) from 2027 through 2029. We estimate that the nets, 46 million of which we think would not otherwise be distributed, will avert roughly 67,000 deaths. We have supported AMF’s work for more than 15 years, and the insecticide-treated nets it procures and distributes remain one of the most cost-effective ways we've found to save lives. 

This grant, which involved a more rigorous investigation pro...

When GiveWell investigates a new cause area, we’re often focused on two priorities: directing funding where we think it can help people most and generating evidence to inform larger investments later. Family planning is a clear example. Recent foreign aid cuts—including reductions from the US, UK, and Dutch governments—deepened an already substantial need and opened up new cost-effective funding opportunities.

When we published our last podcast episode on family planning, GiveWell had made only a couple of small grants. Since then, we’ve made a number of additional grants totaling around $20 million, exemplifying how our...

Diarrhea is one of the leading causes of death for children under five, killing more than 400,000 children every year. GiveWell has funded several programs to prevent and treat diarrhea, and we recently expanded our work by making a grant to support the implementation and evaluation of WASHmobile in the Democratic Republic of the Congo (DRC) and South Sudan. The program, which was developed by Johns Hopkins University, delivers water treatment supplies and hygiene messaging to households at the highest risk of diarrheal disease. It has shown promising results in randomized controlled trials (RCTs) but hasn’t yet been implemented at...

GiveWell tends to be known for its work in areas like malaria prevention, water treatment, and nutrition. But as our research team has grown, so has our ability to search for cost-effective programs across a much wider range of issues.

Serious health problems, such as lack of medical oxygen and stockouts of essential medicines at health facilities, affect millions of people in low-income countries. There may be highly cost-effective solutions to these problems that haven’t been thoroughly evaluated or adequately funded. One of the ways GiveWell is searching for these solutions is through the new ar...

GiveWell tends to be known for its work in areas like malaria prevention, water treatment, and nutrition. But as our research team has grown, so has our ability to search for cost-effective programs across a much wider range of issues.

Serious health problems, such as lack of medical oxygen and stockouts of essential medicines at health facilities, affect millions of people in low-income countries. There may be highly cost-effective solutions to these problems that haven’t been thoroughly evaluated or adequately funded. One of the ways GiveWell is searching for these solutions is through the new ar...

In September 2025, we created a livelihoods research subteam to specifically focus on programs that increase the economic well-being of people in extreme poverty. While we have evaluated and funded livelihoods programs throughout GiveWell’s history, we now have a dedicated program officer overseeing this portfolio, which has allowed us to build on and deepen that work. 

Historically, GiveWell has predominantly focused on health-related programs. Diseases like malaria, diarrhea, and pneumonia can be prevented fairly cheaply, and the evidence for health programs is often strong relative to other areas. As our research team has grown, we’ve been build...

Anemia, which is commonly caused by iron deficiency, can cause fatigue, cognitive impairment, and complications during pregnancy—and it affects roughly a quarter of the world’s population. Over the last decade, GiveWell has directed nearly $50 million to programs to address this health issue. 

Because of the large number of people affected and the low cost to provide people with iron, we are evaluating additional iron fortification and supplementation programs to potentially increase our grantmaking in this area. At the same time, it has been difficult to determine exactly how much providing people with additional iron improves their...

GiveWell’s research doesn’t end once we’ve made a grant. We evaluate a subset of completed grants, comparing what we thought would happen to what actually took place, then try to use what we learn to improve our future funding decisions. Over the past year, we’ve formalized and expanded this work, publishing comprehensive “lookbacks” for select grants.

A recent lookback on grants GiveWell made to fund insecticide-treated net distributions supported by the Against Malaria Foundation (AMF) in the Democratic Republic of Congo (DRC) illustrates the growing capacity of GiveWell’s research team. We drew on multip...

Clubfoot, a congenital condition where children are born with one or both feet twisted inward, affects roughly one in 800 newborns globally. Most of those cases are in low- and middle-income countries, where only about 20% of children with clubfoot receive treatment. 

While most donations to GiveWell are directed to programs that reduce child mortality, our growing research capacity over the last several years has expanded what we’re able to evaluate and fund. One outcome of that work is that we’re better able to direct donations to highly cost-effective programs addressing disabling conditions, like clubfoot, and meaningfully impro...

Vitamin A supplementation is one of the programs GiveWell has supported the longest, and we’re currently funding it in many African countries. The program has an unusually strong evidence base for reducing child mortality, with multiple randomized controlled trials. Yet, as is the case for most global health programs, the evidence for vitamin A supplementation has complex, unresolved questions, such as how well findings from decades-old trials apply today and the extent to which existing research has been influenced by publication bias. As GiveWell’s research team has grown over the last several years, we have expanded our capa...

GiveWell’s primary focus has always been researching, identifying, and directing donations to programs we believe will do the most good. When GiveWell first started, we approached this by looking for organizations that were already delivering highly cost-effective, evidence-backed programs and directing funding to those programs. Over time, we were able to focus further upstream by first identifying highly cost-effective programs and then supporting the development of organizations to deliver them. 

We’ve been able to take an even more expansive view as our research team doubled in size over the last several years. In addition to our c...

GiveWell aims to find and fund programs that will do the most good per dollar. To do this, we carefully evaluate potential grants before making them—assessing academic evidence, building cost-effectiveness models, and talking to people in the sector who know the program well. 

But our work doesn’t stop there. When a program we’ve supported nears the end of their funding, we also regularly evaluate its results to decide whether to continue our support. This typically involves gathering and analyzing extensive monitoring data. In most cases, the results are consistent with what we expe...

Vaccines are remarkably effective at preventing deadly diseases, and, while global needs for them are great, vaccines already receive substantial global funding. This creates a challenge: How do you identify opportunities where additional funding can meaningfully increase vaccination rates and save lives?

GiveWell has long recognized the potential for highly cost-effective vaccine programs. We started supporting vaccination programs in 2015 and have made over $200 million in vaccination-related grants to date. For example, New Incentives, one of our Top Charities, aims to increase routine childhood vaccinations in northern Nigeria by providing small cash incentives to caregivers who bring their...

Seasonal malaria chemoprevention (SMC)—a program that provides preventive antimalarial medication to young children during the months when malaria is mostly likely to be transmitted—is one of the most cost-effective programs GiveWell has identified. Malaria Consortium’s SMC program has been one of our Top Charities since 2016, and we’ve recommended more than $500 million in grants to the program.

Most of our funding to date has supported programs in West Africa, where strong evidence gives us confidence in the effectiveness of the drug combination used. In eastern and southern Africa, malaria chemoprevention programs could po...

GiveWell is often thought of for its Top Charities, but over the last several years, we’ve been substantially broadening our work. We’ve developed new ways to identify potential grantees, funded research to fill gaps in our understanding, and explored new program areas where we believe cost-effective opportunities exist but other funders aren’t investing. This increased breadth isn’t a goal in itself—we’ve been laying the groundwork to deliver more impact, now and in the future.

In this episode GiveWell CEO and co-founder Elie Hassenfeld speaks with Senior Program Officer Julie Faller...

GiveWell has built its reputation on rigorous research—analyzing randomized controlled trials, building cost-effectiveness models, and reviewing monitoring data to identify cost‑effective ways to save and improve lives.

In an effort to supplement this desk research and make better decisions, we’ve been working to gather more information directly from the people who live and work in the countries where we fund programs.

In this episode, GiveWell CEO and co-founder Elie Hassenfeld speaks with Principal Researcher Alex Cohen about GiveWell’s work to gather local insights to check our assu...

Global health programs faced major disruptions to their funding in 2025. Back in March, we published our first podcast episode to share a timely snapshot of the immediate impacts caused by the foreign aid freeze and GiveWell’s initial response strategy. It was unclear whether and when funding would resume, and what the medium and long-term implications would be for life-saving programs. 

Over the last year, GiveWell has drawn on almost two decades of cost-effectiveness research and analysis to assess the effects of this tumult in real time, identify gaps where funding could have exceptional imp...

On Thursday, December 4, 2025, GiveWell hosted a live webinar titled “Growing Needs, Shrinking Aid: Cost-Effective Action in a Year of Funding Cuts.” 

Major cuts to foreign aid this year created deep uncertainty for global health programs. In this live-recorded discussion, co-founder and CEO Elie Hassenfeld moderates a panel of GiveWell researchers to discuss the effects of these cuts and how GiveWell is leveraging its nearly two decades of experience in cost-effectiveness research and analysis to identify opportunities for exceptional donor impact.

The panelists—Rosie Bettle (Program Officer, Malaria), Alex Bowles (Program...

This episode follows up on the November 26, 2025 episode of Planet Money, “Saving lives with fewer dollars,” which covered GiveWell’s evaluation of a grant to the Alliance for International Medical Action (ALIMA) to maintain primary healthcare, hospital services, and malnutrition treatment in two subdistricts of North Cameroon following unexpected aid cuts earlier this year. We recommend listening to the Planet Money episode first, as it provides important context. 

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Significant changes to foreign aid this year created challenges for implementing organizations—and for funders evaluating which programs to support with limited r...

Despite significant progress over the past several decades, malaria remains a leading cause of death globally for children under five. This year’s cuts to foreign aid funding disrupted highly effective programs to prevent malaria, such as seasonal malaria chemoprevention (SMC).  

SMC provides antimalarial medication to children under the age of five during the rainy season when malaria transmission is highest, reducing their risk of dying from the disease. Malaria Consortium’s SMC program, which is one of the most cost-effective programs our researchers have identified, has been one of GiveWell’s Top Charities since 2016, and we’ve recomm...

Our Beyond the Spreadsheets mini-series lets you ride along with our leadership team on their recent weeklong site visit to Malawi. Recorded daily during the trip, the series shares the behind-the-scenes experience of a GiveWell site visit through real-time reflections and clips of conversations. 

On day five, the GiveWell team visited a school in Lilongwe, where they spoke with school representatives and families of students in a nearby urban settlement. On day six, the GiveWell team stopped at a major hospital in Lilongwe to hear from hospital staff and an implementing partner about the i...

Our Beyond the Spreadsheets mini-series lets you ride along with our leadership team on their recent weeklong site visit to Malawi. Recorded daily during the trip, the series shares the behind-the-scenes experience of a GiveWell site visit through real-time reflections and clips of conversations. 

On day four, the GiveWell team visited community projects funded by Spark Microgrants, including a maize mill and a sunflower oil mill, and spoke with residents about their impact. New to the series? Start with day one here. 

Throughout the week, the team visited health cl...

Our Beyond the Spreadsheets mini-series lets you ride along with our leadership team on their recent weeklong site visit to Malawi. Recorded daily during the trip, the series shares the behind-the-scenes experience of a GiveWell site visit through real-time reflections and clips of conversations. 

On day three, the GiveWell team visited a rural health outpost where they met with health care workers to discuss the services they provide through village clinics and home visits—and the impact of foreign aid cuts on their work. Listen to day one and day two of the series her...

Our Beyond the Spreadsheets mini-series lets you ride along with our leadership team on their recent weeklong site visit to Malawi. Recorded daily during the trip, the series shares the behind-the-scenes experience of a GiveWell site visit through real-time reflections and clips of conversations. 

On day two, the GiveWell team met with district health officials to learn about the impact of foreign aid funding cuts and visited a local hospital to review health data. Listen to day one here. 

Throughout the week, the team visited health clinics, schools, and lo...

Our Beyond the Spreadsheets mini-series lets you ride along with our leadership team on their recent weeklong site visit to Malawi. Recorded daily during the trip, the series shares the behind-the-scenes experience of a GiveWell site visit through real-time reflections and clips of conversations. New episodes will be released weekly over the next month, and you can subscribe to be notified when each episode is published. 

At GiveWell, the vast majority of our work is desk-based research—analyzing evidence and modeling program outcomes. Site visits are a small part of what we do, but the...

Foreign aid funding cuts are reshaping the global health landscape, creating urgent funding gaps and forcing difficult prioritization decisions across health systems worldwide. To understand the real-world effects, it’s essential to hear from the organizations working on the front lines with government partners to navigate the funding crisis. The Clinton Health Access Initiative (CHAI) is a large global health nonprofit and an important GiveWell partner in this work.

In this episode, GiveWell CEO and co-founder Elie Hassenfeld speaks with CHAI CEO Dr. Neil Buddy Shah about how the aid cuts are affecting vital he...

GiveWell’s ability to find and fund highly cost-effective health programs relies on a foundation of credible data. A key source of that data, the Demographic and Health Surveys (DHS), recently had its primary funding from USAID discontinued. This creates the potential of a significant challenge for GiveWell’s research—and for evidence-based grantmaking across the global health sector.

In this episode, GiveWell CEO and co-founder Elie Hassenfeld speaks with Senior Researcher Adam Salisbury to explore the implications of this funding gap. They discuss how the DHS program works, why it’s essential for informed...

As GiveWell’s research team grows, that increased capacity and expertise allows us to evaluate a wider range of programs to find the most cost-effective opportunities to help people. Over the past year and a half, we’ve been investigating a new research area—family planning services that help people decide whether and when to have children. 

Family planning programs have particularly complex challenges around targeting, logistics, and ensuring informed and voluntary choice. However, GiveWell's increasing research capacity now positions us to take on new and complex investigations like this. We’ve been reviewing evidence...

Malaria is the cause area where GiveWell has directed the most funding over our 18-year history. We’ve recommended over $1 billion to malaria programs, which we estimate will avert over 200,000 deaths, mostly in young children, through support for programs like Against Malaria Foundation’s insecticide-treated nets and Malaria Consortium’s seasonal malaria chemoprevention.

Despite significant progress against malaria in the past 25 years, malaria is still a leading cause of death globally for children under five. The current status of malaria prevention—and all the progress that’s been made—is now in a precarious position. Si...

GiveWell has long grappled with fundamental questions about how to value different positive impacts and make funding decisions across diverse programs. In particular, how much more valuable it is to save a life than to substantially improve it? And how can we prioritize between programs that achieve those outcomes in different measures when there’s no “right” answer to that question?

In this episode, GiveWell CEO and co-founder Elie Hassenfeld speaks with Senior Program Officer Julie Faller about why GiveWell is dedicating more capacity to researching livelihoods programs that aim to increase people's incomes. They d...

In the face of potential major cuts to foreign aid, how can we anticipate the impact on global health and effectively direct resources to the areas of greatest need?

In this episode, GiveWell’s CEO and co-founder, Elie Hassenfeld, speaks with Principal Researcher Alex Cohen to discuss the forecasting work GiveWell has undertaken to better understand what the future of global health funding might look like. They explore the potential size of the funding gaps, which programs might be affected, and how GiveWell is preparing to respond in a new era for global health ph...

The US government has historically been a major funder of HIV/AIDS programs, providing around $5 to $6 billion annually through PEPFAR and other initiatives. With anticipated major reductions in US government foreign aid, including potential cuts of 20% to 50% to HIV/AIDS funding, GiveWell is assessing where new, cost-effective needs might emerge.

GiveWell aims to find programs where additional funding can have the greatest impact. While HIV/AIDS has not historically been a focus for GiveWell due to substantial US government support, the current funding cuts might lead to potential cost-effective opportunities within HIV/AIDS programming...

Cuts to US government foreign assistance have created unprecedented challenges for global health programs. Countries that have relied on this funding must now navigate substantial gaps and make difficult decisions about program priorities. 

In the fourth episode of GiveWell’s podcast series on these cuts, GiveWell CEO and co-founder Elie Hassenfeld speaks with Program Officer Dan Brown about grants to create technical support units (TSUs) in six African countries. These TSUs will provide support to the ministries of health in Burkina Faso, Democratic Republic of the Congo, Malawi, Nigeria, Uganda, and Zambia as they nav...

The US government has historically spent approximately $12 billion to $15 billion annually in foreign assistance dedicated to global health. The funding cuts announced in the first few months of 2025 disrupted the global health landscape and created the possibility of enormous funding gaps that are still coming into focus. In response, GiveWell has approved around $18 million in grants to support urgent needs—but why has our research led us not to grant more funds yet?

In today’s episode, the third in our series examining the impact of these cuts, GiveWell CEO and co-founder Elie Hassenfeld is j...

Our first episode shared a broad overview of the impacts of US government aid cuts and GiveWell’s initial response. This time, GiveWell Program Officer Natalie Crispin joins CEO and co-founder Elie Hassenfeld to zoom in on a specific case, focusing on grants we’ve made to support urgent funding gaps for seasonal malaria chemoprevention (SMC). 

SMC is one of the most cost-effective programs we’ve found—GiveWell has historically funded around $60-80 million annually for Malaria Consortium’s SMC program, which is one of our Top Charities.  

Elie and Natalie...

In this discussion between GiveWell CEO and co-founder Elie Hassenfeld and Senior Program Officer Julie Faller, we provide snapshots of how US funding changes are affecting global health programs: