Out of Patients with Matthew Zachary

40 Episodes
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By: Matthew Zachary Worldwide

Out of Patients with Matthew Zachary is the longest-running, independent healthcare podcast. Since 2007, Matthew’s been calling out the hypocrisy, hubris, and hostage-taking baked into American healthcare—with a mic in one hand and a middle finger in the other. What started as a pirate radio rebellion is now the most trusted, notorious, and unfiltered show in the game. Patients love it. Industry listens. And anyone who’s ever been gaslit by the system knows exactly where to turn to nod their heads in shared rage.Every episode delivers unsanitized stories, dark humor, policy takedowns, and angsty GenX truth bombs—told by th...

Miss Diagnosed: Sophie Sargent
#413
Last Tuesday at 4:00 AM

Sophie Sargent walked into the studio already owning the mic. A pandemic-era media rebel raised in New Hampshire, trained in Homeland Security (yep), and shaped by rejection, she’s built a career out of DM’ing her way into rooms and then owning them. At 25, she’s juggling chronic illness, chronic overachievement, and a generation that gets dismissed before it even speaks.

We talk Lyme disease, Lyme denial, and the healthcare gaslighting that comes when you “look fine” but your body says otherwise. We dive into rejection as a career accelerant, mental health as content porn, and what it me...


The Uncensored, Unapologetic Olivia Battinelli
#414
Last Tuesday at 4:00 AM

What happens when you hand a mic to the most extroverted, uncensored Gen Z career coach in New York? You get Olivia Battinelli—adjunct professor, student advisor, mentor, speaker, and unfiltered truth-teller on everything from invisible illness to resume crimes.

We talked about growing up Jewish-Italian in Westchester, surviving the Big Four’s corporate Kool-Aid, and quitting a job after 7 months because the shower goals weren’t working out. She runs NYU Steinhardt’s internship program by day, roasts Takis and “rate my professor” trolls by night, and somehow makes room for maple syrup takes, career coaching, and a boyfri...


Building Tools, Not Excuses: Rethinking Healthcare with Marc Elia
09/09/2025

This episode is sponsored by Invivyd, Inc.

Marc Elia is a biotech investor, the Chairman of the Board at Invivyd, and a Long COVID patient who decided to challenge the system while still stuck inside it. He’s not here for corporate platitudes, regulatory shoulder shrugs, or vaccine-era gaslighting. This is not a conversation about politics, but it's about power and choice and the right to receive care and treatment no matter your condition.

In this episode, we cover everything from broken clinical pathways to meme coins and the eternal shame of being old enough to...


LEAD EP5: Redemption
09/02/2025

After years of carrying the weight of lead, Shannon and Cooper find a path out from under the darkness and into the sunlight.

LEAD: how this story ends is up to us is an audio docudrama series that tells the true story of one child, his mysterious lead poisoning, and his mother's unwavering fight to keep him safe. A true story written by Shannon Burkett. Directed by Alan Taylor. Starring Merritt Wever, Alessandro Nivola, Cynthia Nixon, and Cooper Burkett.

Lead was produced by Shannon Burkett. Co-produced by Jenny Maguire. Featuring Amy Acker, Tom Butler, Dennis...


LEAD EP4: The Long Haul
08/26/2025

The deficits from the lead poisoning continue to intensify, Shannon channels her anger and grief into holding the people who hurt her son responsible.

LEAD how this story ends is up to us is a true story written and produced by Shannon Burkett. Co-produced by Jenny Maguire. Directed by Alan Taylor. Starring Merritt Wever, Alessandro Nivola, Cynthia Nixon, and Cooper Burkett.

EP4 features Eboni Booth, Sasha Eden, Kevin Kane, April Matthis, Alysia Reiner, and Mandy Siegfried. Casting by Alaine Alldaffer and Lisa Donadio. Music by Peter Salett. Sound Design by Andy Kris. Recording Engineer Krissopher...


LEAD EP3: Fraying at the Edges
08/19/2025

The effects of the neurotoxin are taking their toll on Cooper as Shannon desperately tries to navigate the severity of their new reality.

LEAD how this story ends is up to us is a true story written and produced by Shannon Burkett. Co-produced by Jenny Maguire. Directed by Alan Taylor. Starring Merritt Wever, Alessandro Nivola, Cynthia Nixon, and Cooper Burkett.

E43 features Jenny Maguire, JD Mollison, Laith Nakli, Deirdre O’Connell, Carolyn Baeumler, Zach Shaffer, and Monique Woodley. Casting by Alaine Alldaffer and Lisa Donadio. Music by Peter Salett. Sound Design by Andy Kris. Recording En...


LEAD EP2 : Stop the Spiral
08/12/2025

As the lead wreaks havoc on Cooper's development, Shannon searches for answers. Desperate to get a handle on what was happening to her son, she grabs onto a lifeboat - nursing school. Andy tries to piece together the past to make sense of the present.

LEAD how this story ends is up to us is a true story written and produced by Shannon Burkett. Co-produced by Jenny Maguire. Directed by Alan Taylor. Starring Merritt Wever, Alessandro Nivola, Cynthia Nixon, and Cooper Burkett

EP2 features Keith Nobbs and Frank Wood. Music by Peter Salett. Sound Design...


LEAD EP1: The Monster in the Walls
08/05/2025

A mysterious dust fills a young family’s apartment. The truth begins to unravel when the mother gets a call from the pediatrician - the monster deep within the walls has been unleashed. 

LEAD how this story ends is up to us is a true story written and produced by Shannon Burkett. Co-produced by Jenny Maguire. Directed by Alan Taylor. Starring Merritt Wever, Alessandro Nivola, Cynthia Nixon, and Cooper Burkett.  

EP1 features Zak Orth, Jenny Maguire, Daphne Gaines, and Micheal Gaston. Music by Peter Salett. Sound Design by Andy Kris. Recording Engineer Krissopher Chevannes. Casting by Al...


Meet My Grief: Notes from an Orphaned Teen
#412
07/29/2025

Lexi Silver is 15 years old. She lost both of her parents before she turned 11. That should tell you enough—but it doesn’t. Because Lexi isn’t here for your pity. She’s not a sob story. She’s not a trauma statistic. She’s a writer, an advocate, and one of the most emotionally intelligent people you’ll ever hear speak into a microphone.

In this episode, Lexi breaks down what grief actually feels like when you’re a kid and the adults around you just don’t get it. She talks about losing her mom on Christmas morni...


The Cancer Fun House: Michele Andrews
#411
07/22/2025

Michelle Andrews built a career inside the pharma machine long before anyone knew what “DTC” meant. She helped launch Rituxan and watched Allegra commercials teach America how to ask for pills by name. Then she landed in the cancer fun house herself, stage 4 breast cancer, and learned exactly how hollow all the “journey” slide decks feel when you’re the one circling the drain.

We talk about what happens when the insider becomes the customer, why pill organizers and wheat field brochures still piss her off, and how she fired doctors who couldn’t handle her will to live. You...


D.A.M.M. Good Trouble: Ann Marie Morse
#410
07/15/2025

Dr. Anne Marie Morse walks into the studio like a one-woman Jersey Broadway show and leaves behind the best damn TED Talk you’ve never heard. She’s a neurologist, sleep medicine doc, narcolepsy expert, founder of D.A.M.M. Good Sleep, and full-time myth buster in a white coat. We talk about why sleep isn’t a luxury, why your mattress does matter, and how melatonin is the new Flintstones vitamin with a marketing budget. We unpack the BS around sleep hygiene, blow up the medical gaslighting around “disorders,” and dig into how a former aspiring butterfly became one...


The Elastic Life of Gigi Robinson
#409
07/08/2025

Gigi Robinson grew up with Ehlers-Danlos syndrome, a disease that turns your joints into overcooked spaghetti. Instead of letting it sideline her, she built a career out of telling the truth about invisible illness. We talk about what it takes to grow up faster than you should, why chronic illness is the worst unpaid internship, and how she turned her story into a business. You’ll hear about her days schlepping to physical therapy before sunrise, documenting the sterile absurdity of waiting rooms, and finding purpose in the mess. Gigi’s not interested in pity or polished narratives. She want...


The Bronx Bleeds Blue: Vanessa Ghigliotty vs. Everyone
#408
07/01/2025

Episode Description:

If you’ve ever wondered what happens when a Bronx-born pediatric nurse with stage 4 colon cancer survives, raises a kid, becomes a policy shark, and fights like hell for the ignored, meet Vanessa Ghigliotty. She’s not inspirational. She’s a bulldozer. We go way back—like pre-Stupid Cancer back—when there was no “young adult cancer movement,” just a handful of pissed-off survivors building something out of nothing. This episode is personal. Vanessa and I built the plane while flying it. She fought to be heard, showed up in chemo dragging her kid to IEP meetings...


Ask Better Questions or Die Trying: Risa Arin
#407
06/24/2025

Risa Arin doesn’t just talk about health literacy. She built the damn platform. As founder and CEO of XpertPatient.com (yes, expert with no E), Risa’s taking a wrecking ball to how cancer education is delivered. A Cornell alum, cancer caregiver, and ex-agency insider who once sold Doritos to teens, she now applies that same marketing muscle to helping patients actually understand the garbage fire that is our healthcare system. We talk about why she left the “complacent social safety” of agency life, how her mom unknowingly used her own site during treatment, what it’s like to pitch c...


Pediatric Engineering for the Rest of Us: Dr. Jamie Wells
#406
06/17/2025

Dr. Jamie Wells is back—and this time, she brought a book. We cover everything from biomedical design screwups to the glorified billing software known as the EHR. Jamie's new book, A Clinical Lens on Pediatric Engineering, is a masterclass in what happens when you stop treating kids like small, drunk adults and start designing medicine around actual human factors. We talk about AI in pediatric radiology, why drug repurposing might save lives faster than biotech IPOs, and the absurdity of thinking one-size-fits-all in healthcare still works.

Jamie’s a former physician, a health policy disruptor, a bioe...


Pinky Swear: Erica Campbell and The Wanted Mastectomy
#405
06/10/2025

Erica Campbell walked away from corporate life, took a hard left from the British Embassy, and found her calling writing checks for families nobody else sees. As Executive Director of Pinky Swear Foundation, she doesn’t waste time on fluff. Her team pays rent, fills gas tanks, and gives sick kids' parents the one thing they don’t have—time. Then, breast cancer hit her. She became the patient. Wrote a book about it. Didn’t sugarcoat a damn thing. We talk about parking fees, grief, nonprofit burnout, and how the hell you decide which families get help and which do...


Dr. Allyson Ocean Unfiltered: Science, Colons and Calling BS
#404
06/03/2025

Allyson with a Y. Ocean with two Ls. And zero chill when it comes to changing the face of cancer care. Dr. Allyson Ocean has been quietly—loudly—at the center of every major cancer breakthrough, nonprofit board, and science-backed gut punch you didn’t know you needed to hear. In this episode, she joins me in-studio for a conversation two decades in the making. We talk twin life, genetics, mitochondrial disease, and why she skipped the Doublemint Twins commercial but still ended up as one of the most recognizable forces in oncology. We cover her nonprofit hits, from Michae...


[BONUS] No One Told Me: COVID and Cancer
05/30/2025

Sponsored by Invivyd, Inc.

Nobody wants to hear about COVID-19 anymore. Especially not cancer patients. But if you’ve got a suppressed immune system thanks to chemo, radiation, stem cell transplants—or any of the other alphabet soup in your chart—then no, it’s not over. It never was. While everyone else is getting sweaty at music festivals, you’re still dodging a virus that could knock you flat.

In this episode, Matthew Zachary and Matt Toresco say the quiet part out loud: many immunocompromised people may not even know they have options beyond vaccines...


Constellations and Cancer: A Storytelling Rebellion with Lisa Shufro
#403
05/27/2025

EPISODE DESCRIPTION

Lisa Shufro is the storyteller’s storyteller. A musician turned innovation strategist, TEDMed curator, and unapologetic truth-teller, Lisa doesn’t just craft narratives—she engineers constellations out of chaos. We go way back to the early TEDMed days, where she taught doctors, scientists, and technocrats how not to bore an audience to death. In this episode, we talk about how storytelling in healthcare has been weaponized, misunderstood, misused, and still holds the power to change lives—if done right. Lisa challenges the idea that storytelling should be persuasive and instead argues it should be connective. We get i...


Dancing Through the Wreckage: Sally Wolf
#402
05/20/2025

What happens when you blend the soul of Mr. Rogers, the boldness of RuPaul, and just a pinch of Carrie Bradshaw? You get Sally Wolf.

She’s a Harvard and Stanford powerhouse who ditched corporate media to help people actually flourish at work and in life—because cancer kicked her ass and she kicked it back, with a pole dance routine on Netflix for good measure.

In this episode, we unpack what it means to live (really live) with metastatic breast cancer. We talk about the toxic PR machine behind "pink ribbon" cancer, how the heal...


OCRA, Acronyms, and Audra: The Nonprofit Multiverse of Madness
#401
05/13/2025

Episode Description

Audra Moran is the President and CEO of OCRA—Ovarian Cancer Research Alliance—which means she spends her days doing things most of us wouldn’t survive five minutes doing: merging nonprofits, leading national patient support programs, funding lifesaving research, surviving pharma grant hell, and trying to reach every woman in America who might be slipping through the cracks. We talk about her time working with the Helen Keller National Center (yes, she knows finger spelling), her accidental journey into cancer nonprofit leadership, the weirdness of dermoid cysts, the ridiculousness of writing grants, and the absolu...


CancerCare Turns 81. Christine Verini Has the Keys
#400
05/06/2025

Christine Verini is a pharmacist by training, a nonprofit CEO by title, and an unapologetic empath by design. She now leads CancerCare, one of the oldest, least-known, and most impactful organizations in the country that actually helps real cancer patients deal with the practical garbage no one likes to talk about—like paying rent, affording a ride to chemo, or feeding their kids.

We talk about her career pivot from industry to impact, what it's like trying to scale empathy without losing your soul, and the daily gut-punch of knowing there are millions of people who still ha...


Jen Finkelstein: Wigs, Wegmans, and War Stories
#399
04/29/2025

Jennifer Finkelstein is not here for your pity, your pinkwashed slogans, or your performative awareness campaigns. She’s a 20-year young adult breast cancer survivor who turned trauma into a blueprint for action and built 5 Under 40, a no-BS nonprofit supporting women diagnosed with breast cancer under 40.

In this episode, we go full Gen X therapy session—from SNL nostalgia and cold caps to the absurdity of finding out you have cancer while looking for the remote. Jen drops real talk about founding a nonprofit when nothing existed for her age group, why mental health support isn’t option...


Kill Bill Meets Jane Fonda: Ilaria Montagnani
#398
04/22/2025

What happens when a black belt, sword-slinging fitness icon gets cancer—twice? She picks up a camera and dares the universe to test her again.

Ilaria Montagnani is not your average anything. She’s been building strong bodies (and stronger minds) for over 30 years as the founder of Powerstrike. She’s part Jane Fonda, part Uma Thurman, and very much the action hero you wish was your personal trainer.

In this episode, we talk about what happens when everything you built your life on—movement, strength, purpose—gets sideswiped by disease. Twice. Ilaria opens up about diag...


Patient No More, Bullsh*t No More: Helene M Epstein
#397
04/15/2025

Helene M. Epstein is not here to make friends with the healthcare system. She's here to dismantle the bullshit, one catastrophic medical error at a time. An ad agency veteran turned patient safety firebrand, Helene’s journey from business development to writer to “badass queen of patient safety,” is one hell of a ride.

We talk about how her son was misdiagnosed over 15 times (yes, really), why some doctors should come with warning labels, and how American healthcare gaslights patients like it's a competitive sport. She also explains why she’s giving away her new book for free, on...


Be Like Zach: Love, Loss, and Legacy
#396
04/08/2025

Jonathan and Jennifer Wall didn’t choose this path, but they’re walking it with purpose. After losing their son, Zach, they turned their grief into action, founding Zach’s Bridge, a lifeline for families navigating pediatric cancer. This episode isn’t about platitudes or silver linings—it’s about the raw, unfiltered reality of love and loss, the relentless unfairness of childhood cancer, and how the Walls are refusing to let their son’s memory fade into the void.

Jon and Jenn open up about what Zach taught them, how they’ve reshaped their lives in his honor, and w...


Love Is Rare. Life Is Strange: My Best Friend Sarah
#395
04/01/2025

Sarah Armstrong—forever Sarah Oakden to me, no matter what the legal documents say—isn't just my best friend. 

She's my first college friend, my musical theater soulmate, and the first person who truly saw me as an artist. She was there when I walked onto Binghamton’s campus, and she was there when I walked into cancer hell. And, because we’re nothing if not in sync, a few decades later, she got her own cancer badge of honor, and I was right there with her every step of the way.

This episode is a love le...


Food for Thought: Cancer, Calories, and Kicking Ass
#394
03/25/2025

Food for Thought: Cancer, Calories, and Kicking Ass

Vanessa Rissetto is back, and she’s bringing the same energy, wit, and unapologetic realness that made her a fan favorite. Last time, we talked nutrition and the rise of Culina Health. This time, life threw her a plot twist—breast cancer. Because, you know, irony.

Vanessa was busy building a nutrition empire when she got diagnosed. So, naturally, she texted, “WTF do I do now?” to her closest cancer Sherpas—yours truly included. Spoiler alert: She powered through, beat cancer, and kept scaling Culina Health to new height...


HPV, Anal Cancer, and the Fabulous Ms. Lillian Kreppel
#393
03/18/2025

EPISODE DESCRIPTION

Lillian Kreppel doesn’t hold back. A seven-year anal cancer survivor and co-founder of the HPV Cancers Alliance, she has made it her mission to challenge stigma, fight misinformation, and push for better awareness of HPV-related cancers. In this episode, she sits down with Matthew Zachary to talk about her journey from high-powered sales to full-time advocacy, the absurd misconceptions surrounding HPV, and why more doctors should be doing rectal exams—but aren’t. With her signature humor and relentless drive, Lillian shares how she turned her diagnosis into a movement, what it takes to make p...


IMPOSSICANT! Grace Charrier’s No-Holds-Barred Cancer Rebellion
#392
03/11/2025

Grace Charrier—a powerhouse advocate, author, and cancer survivor—whose journey from a Stage 3 triple-negative breast cancer diagnosis to global advocacy is nothing short of extraordinary. Originally from Nigeria, Grace's life was upended when she was diagnosed following an unexpected health scare. Instead of retreating, she turned her experience into action, launching Cancer Convos with Grace B, writing the memoir IMPOSSICANT!, and becoming a voice for patients navigating the complexities of cancer care worldwide.

Matthew and Grace dive into the realities of living with cancer, from the absurdities of the U.S. healthcare system to the deeply ingr...


The Art of Healthcare Fuckery
#391
03/04/2025

Buckle up, because Amy Gittelman is back, and this episode is one for the ages. A fellow SUNY Binghamton (yes, we still call it that) alum, Amy joins me for a hilarious and brutally honest deep dive into the absurdities of healthcare, insurance fuckery, and the general nonsense that plagues the system. From dodging medical debt landmines to battling insurance companies that seem hellbent on denying care, we go all in.

But wait—there's more! We reminisce about our Binghamton days, debate the superiority of Wegmans over every downstate grocery store, and expose the dark art of he...


Unf*cking Healthcare with Deb Gordon
#390
02/25/2025

Welcome to another episode of Out of Patients, where we get real about the absolute circus that is the American healthcare system. If you've ever been trapped in a medical billing nightmare, gaslit by insurance reps, or just generally felt like healthcare is an elaborate game designed to screw you—this one’s for you.

Joining me is the indomitable Deb Gordon, a relentless champion for healthcare consumers, co-founder of Umbra Health Advocacy, and co-director of the Alliance of Professional Health Advocates. She literally wrote the book (The Healthcare Consumer’s Manifesto) on navigating this broken system—and she’...


Cancer, AI, and the Meaning of Life
#389
02/18/2025

You know how some people enter your life with a knock, a bang, or maybe even a LinkedIn request? Not Rebecca Batterman, returning champion to Out of Patients, making her dramatic second appearance,

Back in 2019, she karmically appeared like a plot twist in a film noir—unexpected, inevitable, and full of surprises. 

An AI strategist, an optimist (yes, those exist), and a young adult cancer survivor, Rebecca is here to school us on everything from the future of AI in healthcare to why nostalgia is a coping mechanism we all need.  

In this no-B...


The Big Talk: Where Legacy Meets Spotlight
#388
02/11/2025

Tricia Brouk isn’t just a storyteller—she’s a story architect, crafting narratives that connect humanity. A former ballet dancer turned award-winning director, choreographer, and transformational speaker coach, Tricia brings her unique journey to the mic in this captivating conversation. From dancing in iconic opera houses to choreographing Hollywood blockbusters, she has mastered the art of turning moments into movements.

In this episode, Tricia and I dive deep into the magic of storytelling as a service, the difference between telling a story and truly captivating an audience, and how vulnerability can transform lives. Whether you’re looking...


Mad Science: AI, Mental Health, and the Future of Sanity
#387
02/04/2025

Get ready for a wild ride with Matt Lewis, the Tony Stark-meets-Jerry Seinfeld of the mental health AI world. As a multi-degreed polymath, Matt has been ahead of the curve on AI since MySpace was a thing. In this episode, we dive into everything from neuroethics and AI-powered mental health solutions to existential fears of Skynet ruining your day. Matt shares the real scoop on how AI can revolutionize diagnosis, therapy, and even the very definition of sanity—while hilariously lamenting the difficulty of spelling “rhythm.” If you’ve ever wondered whether AI is here to save the world or just...


[BONUS] HannahPod: A Solo Act with Dad
01/30/2025

What happens when you give a 14-year-old the mic and let her fly solo without her twin brother? Magic, that’s what. This episode of Out of Patients features my daughter, Hannah, on her seventh (yes, seventh) appearance on the show, but this time she’s stealing the spotlight solo. From reminiscing about slushy Christmas Eves and rare baby illnesses to deep dives into the hexagonal perfection of honeycombs, this mini-episode is packed with wit, banter, and a healthy dose of dad jokes. We touch on everything from gaming nostalgia to family quirks, proving once again that sometimes the best...


The Natanya Experience: A Tsunami of Wit, Wisdom, and Whoa
#386
01/28/2025

Prepare for a whirlwind of brilliance with Dr. Natanya Wachtel—a self-proclaimed "failed therapist" turned media maven, behavioral strategist, and all-around badass. In this episode, we dive into her transformative journey from navigating personal loss to spearheading innovative mental health initiatives and reimagining her own identity in a world that loves labels. From her esoteric love of theater and eclectic career in Big Pharma to candid insights about obesity, Ozempic, and the not-so-great healthcare system, Natanya delivers an unfiltered look at life’s complexities with humor and heart.

Expect laughs, life lessons, and a few "did-they-really-just-say-that" moments as w...


“Don’t Google It” with Jen Singer
#385
01/21/2025

Back for Round 2 and wielding her wit like a machete, Jen Singer returns to Out of Patients with Matthew Zachary. Cancer survivor, heart failure "graduate," and creator of the 'Just Diagnosed Guides,' Jen has seen it all — and she's here to help YOU see it all more clearly. From dismantling medical jargon to calling BS on "Stay Strong" toxic positivity, this conversation is a masterclass in how to survive, thrive, and laugh in the face of life's curveballs. Need a guide on what to do the day sh*t hits the fan? Jen wrote it. Need permission to be...


No Time for Why: Sean Wachter Returns
#384
01/14/2025

Prepare to be inspired and entertained as Sean Wachter returns to Out of Patients! Sean, aka "The Cancer Fighter," is a two-time melanoma survivor, professional wrestler, coffee shop entrepreneur, and self-proclaimed 'f**ked up Forrest Gump.' With a resume that includes Madison Square Garden, WWE dreams, and a 'We Got This' People's Champion belt, Sean's journey of triumph over cancer (and doctors who didn’t believe him) is nothing short of extraordinary. This episode dives into Sean’s fight against misdiagnosis, his wrestling odyssey, and his hilarious philosophy of not having “time for why.” Get ready for a rollerco...


Mariana Arnaut: The After Cancer
#383
01/07/2025

In this lively and insightful episode of Out of Patients, host Matthew Zachary sits down with Mariana Arnaut, Founder and CEO of The After Cancer, a groundbreaking platform helping cancer survivors navigate the uncharted waters of life post-treatment. Joined by his sharp and witty Chief of Staff, Jen Ramprasad, the trio dives into the gaps in survivorship care, the rise of "cancer retail," and the moral dilemmas of monetizing support services for the cancer community. Mariana also shares the story behind Cards Against Cancer, a clever spin on the popular party game that has sparked meaningful—and sometimes hilarious—conv...