Less of You: Life on Semaglutide & Tirzepatide

Two trips to Spirit Halloween this month, and Eva realizes for the first time in her adult life she can fit into everything instead of eyeing the inflatable dinosaur costume. 

The scale reads 179, a number that hasn't started with a one and a seven since the 1990s, and finally back in a gym she loves: a strength circuit class full of people “kind of old and trying not to die.”

Kami's daughter turns nine, which means a zoo trip that leaves Kami sore for days, a sleepover that falls apart at 3 a.m., and a Halloween calen...

Kami is five days into recovery from a balloon sinuplasty and turbinate reduction, and it has been brutal — she’s too congested to wear her CPAP, she can’t use her mouth guard while mouth-breathing all night, and she’s up every hour drinking water. Before any of that came up, though, she showed off three new waist-length hair extension colors, Foxy, Aurora, and Paprika, from Wildcrafted Beauty.

Eva turns Kami’s rough week into a bigger point from her five years surveying surgery patients: people who are prepared for both the recovery and the price end up far happie...

Eva marched a Stephen King-grade demon clown costume up to the register in a store for kids — and when the manager disagreed that it didn’t belong there, she bought $50 Boden sneakers  out of spite for the place. Weeks later, her 6-year-old still won't go to the bathroom alone, because in her mind, the clown lives there now.

Kami, meanwhile, rides the high of the biggest legal win of her life — a court ruling that her former broker owes her over $6k in commission, plus attorney's fees, after she represented herself start to finish. She's 46 and had never set foo...

Eva hadn't budged from 186 for a year and a half — until she stepped on it this week and saw 180, a number she hasn't seen in ages, ice cream summer in Washington included.

Kami has her own update: three pounds down in her fourth week of GLP-1 shots, plus a blunt reality check on the gastrointestinal side effects nobody warns you about (chewable laxatives included).

Swerving into real life, Kami searches an elderly neighbor's house for his missing 14-year-old cat after he is found on his floor, dehydrated and confused, having fallen some unknown number of days ea...

Three weeks after her Halo resurfacing, Eva decides to take the opportunity to have a Junera laser treatment, a new technology that treats the skin from within to tighten the face and neck from the inside. 

On the morning before heading to Dr. Jennifer Walden’s office in Austin, she took her before photos seriously: the 6:43 AM bathroom pictures, the long-stoplight car selfie video, the in-office clinical photos. 

Then two pills, a grid drawn on her face, almost falling while putting on socks, nitrous held by Jenny (“Feels like high school, huh?”), and a new perspective on what...

After an important discussion about the microwave (also known as the micro-wah-vay), we theorize that GLP-1s are basically commoditized now. 

Meanwhile, to fix the microwave door, Eva's husband drove actual screws through it (that’s not how microwaves work) and we get an update on Kami's small claims case against her former broker.

Eva considers an unexpected opportunity to get her very loose turkey neck skin fixed with the new Junera laser, which was at the top of the wish list someday, and now that day is next Monday.

Kami reports back on her...

After Eva went in for Halo laser resurfacing with a friend (who happens to be one of the best in the world), she walked out looking horrifying (according to the 8 year old) then drove straight to a dance recital tearing a cooling mask in half and swapping it between cheeks.

She’s back with the whole before-and-after saga: the time-lapse, the nitrous oxide she thought she wouldn’t need, a wicked fever-blister flare, and ten full seconds of obsessing over her jawline.

An opportunity to do Junera came up — a thin, spaghetti-like fiber laser that works under t...

After an accidental three-and-a-half-month hiatus, we are back with updates and committing to every week. We catch up on  kids, summer camps, GLP-1 dosing and pricing, HRT and perimenopause, peptides, and one genuinely scary night at the tennis court.

Eva shares what she learned digging into the GLP-1 market, from the shell-website pharmacies to the discovery that most of them source from the same distributor, and how she finally found an affordable telehealth source she trusts that also ships fast and costs a fraction of what she used to pay.

Kami shares how backing off her d...

Kami goes off her GLP-1, stops her thyroid meds, and gains back 25 lbs. After 3 months of Eva being angry for no reason, it turns out she just needs hormones.

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to [email protected].

To help others find great resources for GLP-1 medical weight loss programs, our new list of...

Kami runs out of weight loss meds during the holidays, gains 10 pounds, and blames the dryer for shrinking her clothes. Eva overschedules everything, battles inconsistent clothing sizes at fancy events, and gets unsolicited body size comments at work.

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to [email protected].

To help others find great resources for...

Eva gets ghosted in the middle of an important situation and spirals for a day. Kami stops her meds and finds out what it feels like to be hungry again after two years.

Check out Murderland: Crime and Bloodlust in the Time of Serial Killers

Shop Shapermint

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an ema...

After sewing a quilt on the floor, Kami’s back goes out. After kicking a dumbbell, her foot goes out too.

New compounded meds including glycine and B12 make a noticeable dent in Eva’s persistent body aches. A 3-week pause in medication to get a tooth pulled has a surprising effect. 

We deconstruct our instincts to soften bad news by bribing our children with treats like McDonald’s.

Listen to the new addiction & recovery podcast My Last Relapse

Eva + Kami are two old-ish moms with little kids confronting our reasons for being o...

While working on a project about addiction, Eva realizes she went from drinking and smoking to a food addiction. But she’s not even sure what her “thing” is now, which is… a little terrifying. 

Meanwhile, Kami loses some weight—not exactly from a wellness plan, but courtesy of stress and no sleep. Hey, a win’s a win.

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We...

While wearing a Wonder Woman shirt, Kami heads over to her former workplace to confront her shady former employer after he fails to pay her commission.

Eva’s on a GLP-1 break ahead of a tooth extraction, and gets ready for new head shots for the first time since 2008.

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email...

If you want to keep your meds a secret from someone you live with, here’s how we would keep it secret. 

Kami’s cat, Leonardo Von Flouffe, makes his debut. 

Eva remembers why she was rejected from the United States Marine Corps (really). 

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to [email protected]...

How does being hungry seem to interfere with every activity? 

One child can’t stop eating sugar, the other starts yelling about being hungry while sitting in the 4th row at Mary Poppins, and some mom guilt creeps in over kolaches, portion sizes, and generational food baggage. 

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to podcast...

Kami’s boss’s drinking problem becomes too much. Work drama is affecting her relationship with food too, and she’s trying to reset.

Eva’s prescription changes to a new formula of tirzepatide, B12, and glycine to help with air quotes “muscle fatigue.” 

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to [email protected].

To he...

Ashley tried everything. She tried all the diets: Weight Watchers, Nutrisystem, SlimFast, Houston Methodist Medical Weight Management program. Even after a gastric sleeve, her weight climbed back up to 320 lbs.

Going to therapy for binge eating was good, but still didn’t help her lose weight.

In 2024, exhausted from trying to lose weight yet again, she thought, “screw it, if I’m going to be fat, why not just get rid of my double chin?” So she decided to have neck lift surgery and found a plastic surgeon, and that’s where she discovered GLP-1s by acciden...

Kami forgets to track her calories and take her meds. Eva sends her daughter to camp and Kami remembers getting left behind at camp at age 12, back when there were no cell phones. 


Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to [email protected].

To help others find great resources for GLP-1 medi...

Eva gained a few pounds back and got a muffin top. Kami vs. insurance: It should not be this hard to get sleep apnea treatment.

Yep, you can get a payment plan for weight loss meds. Because results shouldn’t depend on your wallet crying. Learn more about PatientFi!

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email...

Kami broke her foot, and can’t move. Eva ate 4 dark chocolate mini eggs and got sick (4 eggs, not 4 bags of eggs). We beat the question “Don’t you feel totally different now?” to death. 

Kami
SW 250, CW 198, GW 150?

Eva
SW 280, CW 184, GW 170

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@the...

Kami finally busted through the plateau, now hovering at 200 at officially down 50 lbs. Eva’s creeping toward 100 lbs lost,  and had to try on size 8 jeans for the first time since 5th grade. 

For the record, yes, we’ve lost weight, but we’re still the same people on the inside. Stop asking if we “feel great.”

We love that we’re inspiring people to take the plunge! Shoutout to @jennpurrr on Instagram for letting us know we’re the reason she started.

See the Nurri protein shakes from Costco

Listen to our episode with...

In this special bonus episode, an excerpt from a conversation with Los Angeles Addictionologist Dr. Jason Giles about the potential for GLP-1s as a treatment for substance abuse, explaining their impact on cravings and brain chemistry.

Dr. Giles candidly shares his own journey with addiction, how he overcame it, and how it led him to specialize in addiction medicine.

Learn more about Los Angeles addictionologist Dr. Jason Giles

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves...

The Debra returns with a progress update and fills in for Kami, who’s out with the flu. 

She started at 168, now at 154, aiming for 150. It took almost two months before the scale even moved, but she stuck with it.

Hear Debra’s thoughtful tips if you’re thinking about using a GLP-1 to lose weight, and why you should be careful who you tell.

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. ...

Kami stalls at 203 and wonders if it’s time for a higher dose to make it to one-derland. 

Eva shares a jaw-dropping “before” pic from August 2021 after eating at Paula Deen’s while in Nashville. 

Meet Eva’s doctor, Austin plastic surgeon Dr. Johnny Franco

Kami
SW 250, CW 203, GW 150?
Eva
SW 280, CW 189, GW Just Overweight 

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting th...

New to semaglutide or tirzepatide? Here are our tips for what to expect when you are just getting started.  

We survived the mountains of Christmas food and Eva let a wardrobe stylist give her closet a full makeover.

Kami
SW 250, CW 205, GW 150?

Eva
SW 280, CW 194, GW 170?

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story...

Thanksgiving chaos update, questionable ingredients brought by in-laws, a recurrence of rear-end issues, and how Eva got peer-pressured into tucking in a shirt.

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to [email protected].

To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is...

Eva has lost 90 lbs, the equivalent of 9 gallons of paint according to the Lose It! app. It’s Kami’s birthday and she makes big plans for the night. An old friend reaches out at the end of her 2nd month of semaglutide injections with questions about stalled progress. 

Kami SW 250, CW 207, GW 150?
Eva SW 280, CW 189, GW 170?

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d l...

Still blowing money on groceries we end up tossing, planning the menu for Thanksgiving but not planning to binge eat, and excited to have full houses. 

Somehow 100 people subscribed to us on YouTube. We don’t know why, but thanks! Here’s where to subscribe if you haven’t already.

Kami
SW 250, CW 211, GW 150?

Eva
SW 280, CW 192, GW 175

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place.
 
Are you...

Eva feels fat and to feel better tries on the largest jeans she ever owned (size 20W).
Kami gives a fire recovery update while wearing a fox costume for Halloween. 

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to [email protected].

To help others find great resources for GLP-1 medical weight loss programs, our new...

Kami’s 92-year-old neighbor’s house burns down, the 2nd fire in a year of serving on the HOA board. Eva forgets a full order of groceries in the car on a 90-degree day. Life keeps happening, the only difference is that now we forget to eat. 

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to [email protected].

Weigh yourself every day. Don’t weigh yourself every day. Only weigh yourself at the weigh-in. Weigh yourself in the morning after you go to the bathroom. Always weigh yourself at the same time every day. Take off your shoes. Don’t wear jeans to the weigh-in. Don’t drink a lot of water on your weigh-in day. Weigh in on Friday so you can cheat on the weekend. Go to your weigh-in in the morning and not the evening. You can eat whatever you want on cheat day. I only ate zero point food all week. I starved myself this w...

Eva's 30 year high school reunion approaches with the same worries as high school, including what to wear and who will I know? 

Kami’s in full freak-out mode after watching the Oprah special on AI and hearing about scammers using AI to mimic voices.

Then there’s the whole "Oatzempic" thing blowing up TikTok with oat-based smoothies, which sound disgusting. Kami promises to be brave and try this weird drink so you don’t have to.

Read MedScape’s How 'Oatzempic' Stacks up to Ozempic

Watch Oprah’s AI special

Kami’s mom Debra joins with her own skinny shot update after 8 weeks. Kami’s endocrinologist breaks up with her because her thyroid is perfect. Eva worries about a compounded tirzepatide becoming unavailable and attempts to stockpile shots. 

The viral cookbook: What to Cook When You Don't Feel Like Cooking by Caroline Chambers

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your sto...

Because Cassie Layne, FNP, knows the struggle of dealing with weight firsthand, she’s dedicated to making health and wellness accessible for everyone. 

In just over two years, she’s helped over 5,000 people from across all of Indiana reach their weight loss goals with affordable semaglutide for just $98 a month.  One of those people is our very own Kami, the co-host of Less of You! 

Cassie shares inspiring success stories and clears up common misconceptions about these medications.

Learn more about Monarch Health & Wellness 

Follow Cassie on Instagram @monarch_health_wellness

Lea...

Taco Bell’s Meximelt is coming back. Eva’s eyesight improves instead of getting worse for the first time since 8th grade. Kami catches a Facebook Marketplace scammer red-handed. Semaglutide combined with Kami’s appetite suppressing ADHD medication is lowering her already low blood pressure.

Kami
SW 250, CW 221, GW 150?

Eva
SW 280, CW 195, GW 170

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to...

Kami’s daughter’s school bus keeps skipping her stop in the morning. She gets a new job but is then un-hired two days later. While on family vacation in Washington, Eva learns the hard way not to eat Red Vines.

Want your own Less of You sticker? DM us on IG @lessofyoupodcast with your mailing address. 

Kami
SW 250, CW 222, GW 150?

Eva
SW 280, CW 196, GW 170

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarca...

Kami’s job as HOA president takes a stressful turn as she fights with State Farm to get construction moved forward on the 4 houses that burned down over a year ago. 

Eva self-diagnoses a bizarre new side effect of weight loss by reading Reddit comments, and shares an update on the subpoena from our previous episode.
 
To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is live & being updated regularly at lessofyou.com

Kami
SW 250, CW 235, GW 150?

Eva
SW 2...

After losing more than 70 lbs herself, Dr. Sulagna Misra changed her life and now uses her experience to help others do the same. 

Dr. Misra shares her personal weight loss journey, the side effects of GLP-1 she’s experienced personally as well as those her patients have experienced. 

Links

Misra Wellness Direct Physician Care in Encino, California 

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you co...

Continuing our unintentional rear-end-themed mini series with a fissure while on vacation. Is all the weird stuff we talk about helping anyone? Please tell us if it is. 

The murder that made Eva promise to never do nothing again, if you’re curious:     
https://www.startribune.com/stephen-allwine-found-guilty-of-killing-his-wife-staging-death-as-suicide/471981953/

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to...