Brainforest Café

Jonathan Dickinson, co-founder and CEO of Ambio Life Sciences and founder of Terragnosis, joins Dr. Dennis McKenna on the Brainforest Café for a conversation about ibogaine, iboga, and the Bwiti tradition of Gabon.

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Jonathan Dickinson, a Mexico-licensed psychologist and former executive director of the Global Ibogaine Therapy Alliance, Jonathan helped develop the field's foundational safety guidelines and completed the first Nagoya-compliant export of Tabernanthe iboga root. In part one of a two-part conversation, he traces the path from harm reduction work in Vancouver's Downtown Eastside to initiation in Gabon, and explains why i...

What if the future of ayahuasca isn’t in the hype cycle, but in safety, tradition, and real transformation? In this conversation, Sam Believ and Dennis McKenna explore Colombia’s overlooked ayahuasca lineage, the importance of set and setting, and why plant medicine may hold a key to healing both people and culture.

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Sam Believ is the founder of LaWayra Ayahuasca Retreat and host of the Ayahuasca Podcast.

​A former offshore engineer turned modern bridge-builder, Sam is dedicated to making traditional Amazonian medicine accessible, safe, and grounded for the modern world...

In this conversation, Patricia Eastman and Dennis McKenna explore the deeper meaning of psychedelic healing through the lens of ancestral wisdom, initiation, and nature-based practice. Patricia shares the story behind her book Seeding Consciousness and her vision for Hu Azores, a retreat center in Portugal designed as a healing space that integrates architecture, ritual, and circadian-aware design. The discussion moves beyond symptom treatment and into a bigger question: how psychedelics can support creativity, integration, and a more connected human experience.

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Patricia Eastman, Initiated is a Bwiti Traditional Practitioner for over 11 years and...

In 2003, Carlos Tanner woke up in his car underwater, having blacked out behind the wheel and driven into a river. Deep in an opiate addiction, he went to the Amazon to save his own life. What he found there became his life's work. In this episode of the Brainforest Café, Dennis McKenna sits down with Carlos, founder of the Ayahuasca Foundation in Iquitos, Peru, for a wide-ranging conversation on healing, tradition, and what happens when a sacred medicine goes global. Carlos recounts his apprenticeship under the late curandero Don Juan Tangoa Paima, who first took him in, and how t...

In this episode of the Brainforest Café, Dennis McKenna sits down with medicinal chemist Matt Metcalf to explore a genuinely strange frontier: testing drugs in pea seedlings and the touch-sensitive Mimosa pudica instead of in mice. Along the way they circle the question that started it all, why the opium poppy spends so much energy making opioids at all, and what those molecules might be doing inside a plant that has no nerves.

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Matthew Metcalf is a neuroscientist with a background in the medicinal chemistry and pharmacology of opioids and cannabinoids as a...

Dennis McKenna sits down with his old friend Dr. Cedric Baker, an ethnopharmacologist and medical herbalist who studies the ethnobotany of food across more than thirty countries. Together they take apart one of modern medicine's most stubborn assumptions: that food and medicine are separate things. From Thai kitchens where every dish is therapeutic, to the world's longevity hotspots, to the ethics of who owns a plant, it's a conversation that will leave you looking at your own plate a little differently.

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Cedric Barrett Baker is an ethnopharmacologist, food ethnopharmacognoist, medicinal food ethnobotanist...

As the psychedelic renaissance surges, wild sources are collapsing under demand—peyote takes decades to grow, safrole extraction is destroying Southeast Asian forests, and Sonoran Desert toads are being overharvested.

In his book Bioengineering Enlightenment, Prof. Jeffrey Gerst proposes a radical solution: engineer yeast or fast-growing plants to produce psychedelic compounds sustainably. But at what cost? Dennis McKenna warns this could strip these substances from their cultural and ecological roots, veering into biopiracy.

Together, they debate biotech vs. tradition, exploring alternatives like community-led agroforestry, symbiotic rights, and the “Om Fund” to return profits to Indigenous stewar...

Dennis McKenna sits down with journalist Mattha Busby to discuss the evolving world of psychedelics, including ayahuasca, ibogaine, 5-MeO-DMT, coca policy, drug reform, and the risks and realities behind psychedelic retreats and clinics. Mattha shares stories from the front lines of psychedelic journalism and reflects on the cultural, scientific, and political forces shaping the future of consciousness research.

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Mattha Busby is a freelance journalist who has covered drug policy, psychedelics, culture and society for VICE, WIRED, Rolling Stone, The Guardian, LA Times and Esquire. He is the author of two slim volume...

In this rich and thought-provoking conversation, Dennis McKenna speaks with philosopher Mandi Astola about Terence McKenna, psychedelics, epistemology, shamanism, and the nature of knowledge. Together they explore how psychedelic experiences can produce both genuine insight and dangerous overconfidence, why intellectual humility matters, and how science and shamanic ways of knowing can complement each other. The discussion also touches on the “Stoned Ape” theory, the Timewave, the trickster archetype, and the role of psychedelics as tools for understanding reality, consciousness, and human evolution. A fascinating dialogue for anyone interested in philosophy, altered states, ethics, and the limits of what we know...

Join Dennis McKenna and Viktor Wynd for a fascinating conversation on dark fairy tales, strange museum curiosities, Papua New Guinea, storytelling, collecting, and the hidden intelligence of nature.

Viktor Wynd, writer, artist, and founder of the Museum of Curiosities, shares stories from his travels, his love of folklore, and his perspective on art, books, and the living world.

For viewers interested in folklore, ethnobotany, consciousness, rare books, oddities, and the intersection of science, spirit, and wonder.

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Viktor Wynd is a writer, artist, and the proprietor of the eponymous ...

Legal Disclaimer: The following content explores the chemistry and history of psychoactive plants for educational research.

No Medical Claims: The Brainforest Café Podcast and Dennis McKenna do not make any claims regarding the health benefits or safety of the substances discussed. Any statements made by the guest regarding physical effects or health outcomes are personal anecdotes and should not be interpreted as medical advice.

Safety & Legality: This conversation includes theoretical discussions on chemical synthesis. We do not encourage illegal activities or the handling of potentially toxic compounds (such as Ergot fungi). Please adhere to all l...

Join Dennis McKenna in this insightful conversation with Rebecca Lazarou as they explore the urgent need to preserve ancestral medicinal plant knowledge, the role of ethnopharmacology, and how traditional herbal wisdom can be protected for future generations. Rebecca shares the story behind her PhD research on Cypriot medicinal plants and her mission to document at-risk ethnobotanical knowledge before it disappears. They also discuss citizen science, cultural heritage, biodiversity, and the connection between science and traditional healing.

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IMPORTANT NOTICE: Due to unforeseen circumstances the activities for Rebecca's event in London has now shifted...

In this episode of Brainforest Café, Dennis McKenna sits down with award-winning filmmaker Greg Hemmings to discuss the transformative power of storytelling and its ability to catalyze social and environmental change. Greg reveals his personal battle with long COVID and how it led to his Rewiring the Muse project, which uses neuroscience and EEG data to track his recovery. The conversation also explores Greg’s diverse film projects, including the sci-fi series Revival, the scripted feature on homelessness What We Dreamed of Then, and the climate documentary The Berg. It further delves into his profound experience using Wachuma in Per...

Dennis McKenna and OpticMystic explore humble, a graphic meditation on openness, self-questioning, books, technology, AI, love, and the ongoing mystery of what it means to be human.

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OpticMystic a.k.a Hugo Amadeu is just a human fascinated by being alive. He intended to be an astrophysicist or an oceanographer but ended up studying graphic design and becoming a freelancer. He worked on DMT: The Spirit Molecule documentary film by Mitch Schultz, ESPD 50 book and later at the McKenna Academy. Currently, he is working with Namae Ntumae at CWays Home performing all...

In this special crossover episode of Plants of the Gods and Brainforest Café, Dennis McKenna and Mark Plotkin explore sacred plant medicines, psychedelic science, and indigenous wisdom, moving from DMT and ayahuasca to virola snuffs, salvia, ibogaine, and beyond. Originally recorded for Mark´s Podcast “Plants of the Gods”, this rich conversation on ethnobotany, shamanic healing, and the future of psychedelic medicine is now being released as a special crossover on both shows.

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Dr. Mark Plotkin is a renowned ethnobotanist who has spent more than four decades working alongside Indige...

Ethnobiologist Michael Coe returns to Brainforest Café with a special mission: to turn the spotlight onto Dennis McKenna’s lifelong dedication to ayahuasca, visionary plants, and ethnopharmacology. In this intimate conversation, Michael honors Dennis’ 54 years in the psychedelic space, from early fieldwork in the Amazon to pioneering biochemical and pharmacological research on plant medicines. The discussion explores the importance of mentorship, with Dennis now seeing his primary role as supporting a new generation of ethnobiologists like Michael and their work with indigenous communities and threatened medicinal plant traditions. Together, they discuss standing on the shoulders of giants, the challenges of ac...

Discover Una Meistere’s journey from Soviet-era Latvia to becoming a bridge between indigenous plant medicines, psychedelic science, art, and Baltic traditions in this in-depth conversation with ethnobotanist Dennis McKenna. They explore ayahuasca, psilocybin mushrooms in Latvia, Amanita muscaria, and ancient sauna rituals as a kind of “Latvian ayahuasca,” touching on symbiosis with nature and how psychedelic experiences can help heal our disconnection from the natural world. ​ Una shares how synchronicities led her from journalism to co-founding Arterritory, Spiriterritory, and the NGO Veseliba Latvija, and to organizing the first psychedelic science conferences in Latvia together with the University of Latvia...

Michael Coe is an ethnobiologist and applied ecologist with a Ph.D. in Evolution, Ecology, and Conservation Biology. As an Assistant Professor at Tarleton State University, his teaching and research focuses on the relationships between humans, ecosystems, and traditional knowledge systems. Passionate about biodiversity and the sustainable management of natural resources, Michael brings a dynamic interdisciplinary perspective, helping to integrate contemporary ethnobiology and ecology with traditional ecological practices to inform sustainable use strategies, conservation priorities, and global medicine security.  Michael is the principal investigator (PI) for the COE LAB where they are conducting hypothesis driven research in ethnobiology and h...

Michael Coe is an ethnobiologist and applied ecologist with a Ph.D. in Evolution, Ecology, and Conservation Biology. As an Assistant Professor at Tarleton State University, his teaching and research focuses on the relationships between humans, ecosystems, and traditional knowledge systems. Passionate about biodiversity and the sustainable management of natural resources, Michael brings a dynamic interdisciplinary perspective, helping to integrate contemporary ethnobiology and ecology with traditional ecological practices to inform sustainable use strategies, conservation priorities, and global medicine security.  Michael is the principal investigator (PI) for the COE LAB where they are conducting hypothesis driven research in ethnobiology and h...

Terence McKenna was the stand‑up philosopher of the apocalypse. A cognitive libertarian. The anti‑guru who rejected authority—even his own. Twenty‑five years after his passing, the “Tryptamine Elf King” still haunts the present, reverberating through the sensorium of a new generation.

Inspired by Graham St John’s definitive magnum opus, Strange Attractor: The Hallucinatory Life of Terence McKenna, the inner circle—the family, the friends, and the co‑conspirators who knew the man behind the myth—came together for an extraordinary online conversation.

PANELISTS BIOGRAPHIES:

Dennis McKenna and his brother Terence...

Terence McKenna was the stand‑up philosopher of the apocalypse. A cognitive libertarian. The anti‑guru who rejected authority—even his own. Twenty‑five years after his passing, the “Tryptamine Elf King” still haunts the present, reverberating through the sensorium of a new generation.

Inspired by Graham St John’s definitive magnum opus, Strange Attractor: The Hallucinatory Life of Terence McKenna, the inner circle—the family, the friends, and the co‑conspirators who knew the man behind the myth—came together for an extraordinary online conversation.

PANELISTS BIOGRAPHIES:

Dennis McKenna and his brother Tere...

Sharon McKenna is the director and producer of the forthcoming feature documentary, “It’s Going to Get Weirder: The Terence McKenna Story.”

Sharon  is a writer, film director, and journalist whose work has appeared in a range of outlets, from several alternative weeklies to MSNBC digital, among others. Her career spans three-plus decades of network news production, investigative reporting, corporate creative work and screenwriting. Her screenplays have been optioned and won numerous awards, and she has worked as a script reader and consultant for several film production companies.

She is a member of the International Documen...

Sharon McKenna is the director and producer of the forthcoming feature documentary, “It’s Going to Get Weirder: The Terence McKenna Story.”

Sharon  is a writer, film director, and journalist whose work has appeared in a range of outlets, from several alternative weeklies to MSNBC digital, among others. Her career spans three-plus decades of network news production, investigative reporting, corporate creative work and screenwriting. Her screenplays have been optioned and won numerous awards, and she has worked as a script reader and consultant for several film production companies.

She is a member of the International Documen...

Nissan started his career as a medical doctor and began his work as a general practitioner in an urban community clinic system. He then specialized in ophthalmology and practiced in a small town for 36 years. He became dissatisfied working strictly on the physical level and received training in Gestalt psychotherapy and had a small private practice. He became interested in the field of Natural Vision Improvement which combined his interest in vision with present moment, embodied presence. A reading from a tarot card reading psychic suggested the need for working in and with the spiritual realm to facilitate the...

Nissan started his career as a medical doctor and began his work as a general practitioner in an urban community clinic system. He then specialized in ophthalmology and practiced in a small town for 36 years. He became dissatisfied working strictly on the physical level and received training in Gestalt psychotherapy and had a small private practice. He became interested in the field of Natural Vision Improvement which combined his interest in vision with present moment, embodied presence. A reading from a tarot card reading psychic suggested the need for working in and with the spiritual realm to facilitate the...

Nissan started his career as a medical doctor and began his work as a general practitioner in an urban community clinic system. He then specialized in ophthalmology and practiced in a small town for 36 years. He became dissatisfied working strictly on the physical level and received training in Gestalt psychotherapy and had a small private practice. He became interested in the field of Natural Vision Improvement which combined his interest in vision with present moment, embodied presence. A reading from a tarot card reading psychic suggested the need for working in and with the spiritual realm to facilitate the...

Zina Brown is the writer and director of The Faerie Rings, an upcoming narrative feature film
about the promise of visionary plant medicines, and the cruelty of those who would outlaw
them.
Zina’s unique visual and narrative style has been awarded in film festivals across the world,
including the Barcelona International Environmental Film Festival, Kyiv Film Festival in
Ukraine, Mexico City International Film Festival, Amsterdam International Film Festival, San
Antonio Film Festival, and the Woods Hole Film Festival.
He has over 25 years of writing and directing experience, including numerous music videos

Zina Brown is the writer and director of The Faerie Rings, an upcoming narrative feature film
about the promise of visionary plant medicines, and the cruelty of those who would outlaw
them.
Zina’s unique visual and narrative style has been awarded in film festivals across the world,
including the Barcelona International Environmental Film Festival, Kyiv Film Festival in
Ukraine, Mexico City International Film Festival, Amsterdam International Film Festival, San
Antonio Film Festival, and the Woods Hole Film Festival.
He has over 25 years of writing and directing experience, including numerous music videos

Kevin Reed, founder and president of the Entheogen Stewardship Project, a vital new nonprofit organization dedicated to protecting culturally significant plant and animal species sacred to indigenous communities worldwide.
Kevin brings a remarkable 45-year journey as a student of psychedelic science and culture to this crucial conservation work. His path began in 1984 under the mentorship of legendary researchers Sasha and Anne Shulgin, followed by profound connections with iconic figures including Wavy Gravy, Jack Herer, Timothy Leary, Rick Strassman, and many others who have shaped the modern psychedelic renaissance.
Kevin's hands-on expertise spans an impressive range of fields...

Kevin Reed, founder and president of the Entheogen Stewardship Project, a vital new nonprofit organization dedicated to protecting culturally significant plant and animal species sacred to indigenous communities worldwide.
Kevin brings a remarkable 45-year journey as a student of psychedelic science and culture to this crucial conservation work. His path began in 1984 under the mentorship of legendary researchers Sasha and Anne Shulgin, followed by profound connections with iconic figures including Wavy Gravy, Jack Herer, Timothy Leary, Rick Strassman, and many others who have shaped the modern psychedelic renaissance.
Kevin's hands-on expertise spans an impressive range of fields...

Graham St John, PhD, is a cultural anthropologist and historian of transformational events, movements, and figures. His forthcoming book Strange Attractor: The Hallucinatory Life of Terence McKenna (MIT Press, Oct 7, 2025) is the latest among his ten books, which also include Mystery School in Hyperspace: A Cultural History of DMT (North Atlantic Books 2015). Graham is Senior Research Fellow in the Department of Media, Humanities and the Arts at the University of Huddersfield, UK.

Graham St John, PhD, is a cultural anthropologist and historian of transformational events, movements, and figures. His forthcoming book Strange Attractor: The Hallucinatory Life of Terence McKenna (MIT Press, Oct 7, 2025) is the latest among his ten books, which also include Mystery School in Hyperspace: A Cultural History of DMT (North Atlantic Books 2015). Graham is Senior Research Fellow in the Department of Media, Humanities and the Arts at the University of Huddersfield, UK.

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Graham St John, PhD, is a cultural anthropologist and historian of transformational events, movements, and figures. His forthcoming book Strange Attractor: The Hallucinatory Life of Terence McKenna (MIT Press, Sep 30, 2025) is the latest among his ten books, which also include Mystery School in Hyperspace: A Cultural History of DMT (North Atlantic Books 2015). Graham is Senior Research Fellow in the Department of Media, Humanities and the Arts at the University of Huddersfield, UK.

Chapters

Graham St John, PhD, is a cultural anthropologist and historian of transformational events, movements, and figures. His forthcoming book Strange Attractor: The Hallucinatory Life of Terence McKenna (MIT Press, Sep 30, 2025) is the latest among his ten books, which also include Mystery School in Hyperspace: A Cultural History of DMT (North Atlantic Books 2015). Graham is Senior Research Fellow in the Department of Media, Humanities and the Arts at the University of Huddersfield, UK.

Learn more about your ad choices. Visit megaphone.fm/adchoices

Tony Ācworth (pronounced Ayk-worth) is a visionary herbalist, psychedelic advocate, forest guide, and self-described “wily wizard” living with his wife and five-year-old son amid the coastal rainforests of Brentwood Bay, Vancouver Island.

For 15 plus years, Tony has walked the plant (and mushroom) path, logged over 5,000 clinical hours doing comprehensive intakes with patients, helping them untangle what truly plagues the mind, body, and spirit. Under the mentorship of herbal elder and prolific author and mycologist Robert Rogers, Tony deepened his reverence for the fungal world and its wisdom.

In 2015, he was hired to work in Pa...

Tony Ācworth (pronounced Ayk-worth) is a visionary herbalist, psychedelic advocate, forest guide, and self-described “wily wizard” living with his wife and five-year-old son amid the coastal rainforests of Brentwood Bay, Vancouver Island.

For 15 plus years, Tony has walked the plant (and mushroom) path, logged over 5,000 clinical hours doing comprehensive intakes with patients, helping them untangle what truly plagues the mind, body, and spirit. Under the mentorship of herbal elder and prolific author and mycologist Robert Rogers, Tony deepened his reverence for the fungal world and its wisdom.

In 2015, he was hired to work in Pa...

Dr Harry Shirley has a PhD in organic chemistry and research experience at the
University of Oxford. His research focussed on the synthesis of biologically active chemicals
of marine origin. Having left academia some years ago, he now holds a deep passion for
Jungian thought. He recently published his paper “the Buddhabrot and the Unus Mundus” in
the International Journal of Jungian Studies, which explores the role of the Mandelbrot set in
mind and matter.

Dr Harry Shirley has a PhD in organic chemistry and research experience at the
University of Oxford. His research focussed on the synthesis of biologically active chemicals
of marine origin. Having left academia some years ago, he now holds a deep passion for
Jungian thought. He recently published his paper “the Buddhabrot and the Unus Mundus” in
the International Journal of Jungian Studies, which explores the role of the Mandelbrot set in
mind and matter.

Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Andrew Gallimore is a computational neurobiologist, chemical pharmacologist, and writer, living and working in Tokyo. He has a master’s degree in chemical pharmacology and a PhD in biological chemistry from the University of Cambridge and has held postdoctoral research fellowships in computational neuroscience at the Universities of York, Oxford, and Okinawa. He has been fascinated by the neuropharmacology of psychedelics for more than two decades and is the author of three books: Alien Information Theory -- Psychedelic Drug Technologies and the Cosmic Game; Reality Switch Technologies -- Psychedelics as Tools for the Discovery and Exploration of New Wo...

Dr. Andrew Gallimore is a computational neurobiologist, chemical pharmacologist, and writer, living and working in Tokyo. He has a master’s degree in chemical pharmacology and a PhD in biological chemistry from the University of Cambridge and has held postdoctoral research fellowships in computational neuroscience at the Universities of York, Oxford, and Okinawa. He has been fascinated by the neuropharmacology of psychedelics for more than two decades and is the author of three books: Alien Information Theory -- Psychedelic Drug Technologies and the Cosmic Game; Reality Switch Technologies -- Psychedelics as Tools for the Discovery and Exploration of New Wo...