The Dr. Gabrielle Lyon Show
The Dr. Gabrielle Lyon Show promotes a healthy world, and in order to have a healthy world, we must have transparent conversations. This show is dedicated to such conversations as the listener; your education, understanding, strength, and health are the primary focus. The goal of this show is to provide you with a framework for navigating the health and wellness space and, most importantly, being the champion of your own life. Guests include highly trustworthy professionals that bring both the art and science of wellness aspects that are both physical and mental. Dr. Gabrielle Lyon is a Washington University fellowship-trained...
How to Stay Calm in a Crisis and Why Detachment Is a Trainable Skill - Jamie Cochran
Your ego isn’t the enemy, but if you’re not actively controlling it, it is running your team, your home, and your most important relationships. Jamie Cochran, COO of Echelon Front, has spent 13 years helping leaders fix the root cause most of them never look for.
The Women’s Leadership Assembly live event runs January 5–7, 2027 in Palm Springs. A free monthly webinar series runs year-round. More details here: https://events.echelonfront.com/product/assembly-004/?utm_source=google&utm_medium=cpc&utm_campaign=22652941380&utm_content=&utm_term=&utm_source=google&utm_medium=paid&utm_campaign=22652941380&utm_cont...
Penis Health, What Every Man Needs to Know - Dr. Amy Pearlman
Most men think erectile dysfunction is a bedroom problem. It's actually one of the earliest warning signs of cardiovascular disease, capable of showing up three to five years before a heart attack.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Amy Pearlman, a urologist trained in men's sexual health, to discuss:
Why ED is a symptom of vascular health, not a standalone disease and how the artery feeding the heart is roughly double the size of the one feeding the penis, so problems show up "down there" firstWhy "normal" testosterone can be...Your Doctor Is Watching the Wrong Number. LDL, ApoB & Heart Risk Explained. - Dr. Kevin Maki
Most people think the cholesterol number on their lab report tells them whether their heart is at risk. But former National Lipid Association President Dr. Kevin Maki explains that LDL is just one piece of a much bigger picture and focusing on it alone can mean missing the markers that matter most.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Kevin Maki, former President of the National Lipid Association and co-editor-in-chief of the Journal of Clinical Lipidology, to discuss:
Why ApoB and Lp(a) are better predictors of heart risk than LDL...The Cancer Doctors Keep Missing in Young Adults - Dr. Michelle Pearlman
Colorectal cancer is now the leading cancer killer in adults under 50, and patients in their 20s are presenting with metastatic disease that has nothing to do with family history. Most physicians are still telling young patients with rectal bleeding that it's probably just hemorrhoids and that's costing lives.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Michelle Pearlman, a board-certified gastroenterologist and founder of a Miami-based gastro-metabolic clinic, to discuss:
The specific warning signs every adult under 50 should never ignore, regardless of age including rectal bleeding, unintentional weight loss, and persistent abdominal...Jocko Willink - Parenting, Apex Kid Myth, Failure, & Leadership
Most parents are quietly paving the road their kids were supposed to learn to walk on by themselves and Jocko Willink has spent 20 years watching what happens when that road is too smooth.
In this episode, Dr. Gabrielle Lyon sits down with Jocko Willink, retired Navy SEAL commander, founder of Echelon Front, and bestselling author of Extreme Ownership and Discipline Equals Freedom, to discuss:
Why the "apex parent / apex kid" mindset is a quiet trap, and what to do instead of paving the roadHow nature vs nurture actually plays out and what you can and cannot...Doctors Are Removing Testicles for This | Dr. Susan Macdonald
Most men don't know they have a pelvic floor, and most doctors aren't trained to look for dysfunction in it. The result: testicles are being surgically removed for pain that's actually neuropathic, at double the rate of a far more effective nerve-sparing procedure.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Susan Macdonald, a board-certified urologist, surgical program director at Penn State, and one of only ~30 U.S. specialists treating chronic pelvic pain in men, to discuss:
Why "prostatitis" is often the wrong diagnosis, and how rounds of antibiotics mask the real...Mark Bell on Fat vs. Carbs, What’s Really Making You Fat?
Most people are chasing the wrong version of strength and paying for it with pain, poor movement, and a body that breaks down faster than it should. In this episode, Dr. Gabrielle Lyon sits down with Mark Bell, elite powerlifter, entrepreneur, and founder of Slingshot, to discuss:
Why strength training is essential at every age but most people are defining "strength" too narrowlyHow modern life has created an "exercise deficiency," and why artificial exercise is the only fixThe truth about fat, protein, and the biggest nutrition mistakes holding people back from lasting weight lossThe emerging peptide...GLP-1 Side Effects, Risks, And Who Should Actually Be Using It | Dr. Christle Guevarra
We are living through one of the most significant shifts in medicine in generations, and most people don’t fully understand what it means. Dr. Christle Guevarra joins me to zoom out on the entire GLP-1 landscape; from the drug’s origins as a modest diabetes treatment in 2005 to today’s third-generation medications still moving through clinical trials, and what all of it means for the future of obesity, performance, and longevity.
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Dominique Sachse on Aging Well, HRT, and Building Muscle After 50
The moment you decide to show up publicly, you open the door to opinions from people who would never say those things to your face. Dominique Sachse, journalist, author, and content creator who has lived her life on camera for over three decades, gets honest about what it costs to put yourself out there, why online cruelty is a psychology problem more than a content problem, and how “Teflon Dom” developed the thick skin to let none of it redirect her.
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The Truth about Saturated Fat, Omega-3 Fatty Acids and Total Mortality | Dr. Tom Brenna
Only nine scientists were asked to advise on the 2025 Dietary Guidelines for Americans, and Dr. Tom Brenna was one of them. In this conversation, he pulls back the curtain on how dietary guidelines are actually made, why the process has never been the same twice, and what it was like to watch a decades-old saturated fat recommendation get carried forward despite a lack of evidence supporting it at the level of total mortality. This is the dietary guidelines conversation the internet has been missing: straight from someone who was actually in the room.
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GLP-1 Drugs & Bariatric Surgery Explained by a Top Obesity Researcher | Dr. David Allison
In a world flooded with conflicting health advice, how do you actually figure out what’s true? Dr. David Allison, one of the most rigorous scientific minds in obesity and nutrition research, shared the exact framework he uses to evaluate evidence, from peer-reviewed trials to podcast recommendations to AI-generated summaries. He explains the difference between trusting science as a process and trusting individual studies, why most nutrition epidemiology functions more like advertising than research, and how ordinary people can build a reliable filter for health claims without a PhD.
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Dr. Tommy Wood: Can Cognitive Decline Be Reversed?
Up to 70% of dementia may be preventable, so why aren’t more people talking about what actually drives cognitive decline? In this episode, I’m with Dr. Tommy Wood, neuroscientist and author of “The Stimulated Mind,” to explore the lifestyle levers that protect your brain across a lifetime. Learn how white matter hyperintensities develop and whether they can reverse, what MCTs and ketones actually do for a glucose-starved brain, and why social connection may be the most underrated variable in cognitive aging. What is the one change you could make today that would most protect your brain tomorrow?
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HIIT vs. Moderate Intensity Exercise - Which Is Better for Your Health? | Dr. Martin Gibala
Metabolic flexibility is your body’s ability to efficiently burn fat or carbohydrate depending on demand, may be one of the most important and least understood markers of long-term health. In this episode, I’m with Dr. Martin Gibala to explore the emerging science of Fat Max, why mitochondrial quality is central to both performance and longevity, and how sprint interval training produces comparable mitochondrial adaptations to traditional endurance work in a fraction of the time. Could the key to better metabolic health be less about the hours you log and more about how hard you’re willing to push?<...
Danica Patrick Opens Up About Breast Implant Illness, Inflammation, and Starting Over
The most decorated woman in motorsports history will tell you she feared losing far more than she loved winning, and that fear is exactly what drove her to the top. In this episode, I’m with racing legend Danica Patrick to unpack the psychology of elite performance, from the “blind faith” that carried her through two decades of racing to the nervous system conditioning she built starting at age 10. What would be possible for you if you learned to channel pressure instead of escaping it?
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Hormone Replacement Therapy, What Every Woman Needs to Know in 2026 | Dr. Heather Hirsch
I’m joined by Dr. Heather Hirsch to debunk the persistent myths surrounding hormone replacement therapy and explain why the 2002 Women’s Health Initiative data was so widely misinterpreted. We discuss how optimized estrogen, progesterone, and testosterone levels can protect your heart, bones, and brain health, helping you move past "normalized suffering" and into a proactive state of longevity. Whether you are in perimenopause or well past the ten-year window, you'll learn how to navigate personalized dosing and clinical data to reclaim your vitality and extend your health span.
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Male Fertility and Sperm Health: What Your Sex Drive and Testosterone Really Mean | Dr. Michael Eisenberg
Male fertility is declining, and most men have no idea why.
In this episode of The Dr. Gabrielle Lyon Show, Dr. Gabrielle Lyon sits down with Dr. Michael Eisenberg, Director of Male Reproductive Health at Stanford University and Chief Medical Advisor of SwimClub, to break down what truly determines sperm health and reproductive success.
They discuss:
How metformin, GLP-1 medications, testosterone therapy, and anabolic steroids affect male fertilityWhy sperm count is a powerful biomarker for long-term health and longevityThe role of sleep, muscle mass, exercise, diet, marijuana, and environmental toxins like microplasticsWhether platelet-rich plasma...Why You Don’t Believe in Yourself (And How to Fix It) | Dr. Shadé Zahrai
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Self-doubt holds more people back than lack of skill or intelligence.
In this episode, Dr. Gabrielle Lyon sits down with Dr. Shadé Zahrai to explore the science of confidence, self-trust, and peak performance. They break down why confidence comes after action, how self-image shapes success, and the four psychological drivers that determine whether you thrive or stay stuck.
You will learn how body language influences perception, why high performers plan for failure, how perfectionism leads to burnout, and the subtle communication h...
How to Eat for Strength, Metabolism, and Longevity
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This episode brings together standout moments from The Forever Strong Experience, packed into one powerful episode.
Featuring highlights from:
Dr. Mark Hyman – Founder of the Cleveland Clinic Center for Functional Medicine, co-founder and CMO of Function Health, director of The UltraWellness Center, host of The Dr. Hyman Show (300M+ downloads), and 15x New York Times bestselling author, including Young Forever and Food Fix Uncensored.Layne Norton, PhD – Nutritional scientist, 4x USA Powerlifting National Champion and 2024 IPF M1 World Champion (93kg), record-setting deadlifter, coac...Protein First: How the New Dietary Guidelines Shift Nutrition
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In this episode, Dr. Gabrielle Lyon sits down with Dr. Donald Layman, one of the world’s leading protein researchers and a key contributor to the newly released U.S. Dietary Guidelines. They explore why the old food pyramid failed, how nutrition science became driven by ideology instead of evidence, and what the updated guidelines finally get right about protein, fats, and carbohydrates. Dr. Layman explains why the long-standing protein recommendation of 0.8 g/kg was never intended for optimal health and how higher protein intake su...
The Forever Strong PLAYBOOK: Your 6-Week Field Manual for Muscle-Centric Longevity
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In this solo episode, Dr. Gabrielle Lyon shares the deeper mission behind The Forever Strong PLAYBOOK and the philosophy that has guided her work for decades.
This conversation is not about trends, quick fixes, or aesthetics. It is about building strength as a lifelong responsibility and understanding why skeletal muscle is the foundation of health, resilience, and independence across the lifespan.
Dr. Lyon introduces the Forever Strong ethos and walks...
You Don’t Need Confidence, Just Do THIS | Leila Hormozi
Pre-order The Forever Strong PLAYBOOK today to unlock over $400 in free bonuses and learn how to build the muscle, resilience, and metabolic health that actually determine how well you age. https://drgabriellelyon.com/playbook/
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In this episode, Gabrielle Lyon sits down with Leila Hormozi to discuss the journey from grit to empathy in both personal and professional life. Leila shares candid stories of building her first business, the sacrifices involved, and how her experiences in fitness shaped her entrepreneurial mindset. The conversation explores...
Willpower vs. Systems: Why Your Diet Fails & How to Fix Your Relationship w/ Food | Sohee Carpenter
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In this episode, Dr. Gabrielle Lyon is joined by Sohee Carpenter, PhD, to explore the complex intersection of psychology, eating behavior, and resistance training. Dr. Carpenter shares her personal journey from struggling with eating disorders to becoming a leading expert in sports science, offering a unique perspective on why high achievers often struggle with diet adherence.
They dive deep into the...
The Gut-Muscle-Immune Axis: How Mitophagy Rewires Your Body for Longevity
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Are your immune cells aging faster than you are? In this episode, Dr. Gabrielle Lyon sits down with Dr. Anurag Singh, a leading physician-researcher and Chief Medical Officer at Timeline, to discuss a groundbreaking discovery: the gut-muscle-immune axis.
While we often focus on muscle mass for longevity, new research published in Nature Aging reveals that our immune system undergoes a similar...
The Joint Health Blueprint: Preventing Arthritis, Frozen Shoulder, and Bone Loss as You Age
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If you are only focusing on building muscle, you are missing half the equation for long-term mobility. In this mashup episode, Dr. Gabrielle Lyon brings together top orthopedic experts to discuss the critical importance of joint and tendon health.
While muscle develops relatively quickly, your tendons and ligaments can take 6 to 9 months to fully adapt to a new training stimulus. This...
Hormone Replacement Therapy Decoded: Why the FDA Removed the Blackbox Warning on HRT
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Dr. Jen Ashton on Unimaginable Loss, Mental Health, and Post-Traumatic Growth
If you or someone you know is experiencing suicidal thoughts, emotional distress, or a mental health crisis, call or text 988, or chat via 988lifeline.org.
Support is available 24/7. You are not alone, and help is available.
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Dr. Gabrielle Lyon sits down with renowned medical correspondent and OB/GYN, Dr. Jen Ashton, for a prof...
STOP Inflaming Your Body: The #1 Enemy to Egg Quality and Conception
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Dr. Gabrielle Lyon sits down with fertility specialist Dr. Natalie Crawford to tackle the urgent rise in infertility across both men and women. Dr. Crawford, an advocate for proactive reproductive health, reveals why inflammation is hijacking your fertility and why the old dogma that "age is the only factor" for egg quality is dangerously incomplete.
They cover critical, actionable steps—from the most i...
Carbs vs. Protein: Which Macronutrient Is Actually More Dangerous to Overconsume?
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Dr. Gabrielle Lyon reveals the biggest mistakes Americans make with their nutrition and body composition, especially after age 40. With 75% of Americans overweight or obese, the problem is clear: excess calories from cheap, processed carbohydrates.
Dr. Lyon dissects the metabolic science, explaining why skeletal muscle—the largest organ—is not designed to dispose of the massive carb loads found in the average American...
Over 70 and Shredded: The Guide to Building Muscle at Any Age | Michelle & Joan MacDonald
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In this empowering episode, Dr. Gabrielle Lyon sits down with the incredible mother-daughter duo, Michelle and Joan MacDonald, to share the blueprint for radical physical transformation at any age. Joan, who began her journey nearing 71 years old, proves it's never too late, while coach Michelle, a Certified Strength and Conditioning Specialist (CSCS), cuts through the...
TRT: Your Complete Guide to Safe Dosing, Risks, and Boosting Longevity
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In this compilation episode, Dr. Gabrielle Lyon is joined by the top experts in Testosterone and men's health treatments.
You'll learn:
Why aging alone doesn't drop T levels and why acquisition of conditions like obesity is the real culprit.Why the standard "low T" cutoff is misleading and why you must check your Free Testosterone.How erectile dysfunction is a...Neuroscientist Explains MDMA and The Science of Social Connection | Dr. Ben Rein Ph.D.
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In this fascinating episode, Dr. Gabrielle Lyon talks with neuroscientist Dr. Ben Rein, PhD (author of Why Brains Need Friends), about the science of social connection, emotion, and cognitive health. Dr. Rein, an expert in neurobiology and psychedelic research, reveals the cutting-edge studies that explain why loneliness is as damaging as smoking and how our digital world is affecting our brain's ability to...
Sex Therapist explains The Science-Backed Guide to a Better Sex Life | Marianne Brandon
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In this explosive episode, Dr. Gabrielle Lyon sits down with relationship expert Marianne Brandon to confront the modern crisis of intimacy and sexual wellness. They dive into how the digital world—including porn, AI companions, and VR technology—is creating an evolutionary mismatch that clashes with our primal needs for bonding, leading to rising loneliness and sexual dysfunction.
Dr. Lyon and Marianne Bran...
The Menstrual Cycle DECODED: Fertility, PCOS, and the New Science of Hormones
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In this episode, Dr. Gabrielle Lyon sits down with Dr. Heidi van den Brink; one of the only scientists in the world studying the ovarian transition from fertility to menopause. Together, they unpack what textbooks and wellness influencers often miss: the biology behind how your ovaries, uterus, metabolism, and nutrition interact across every stage of a woman’s life.Â
Dr. Heidi revea...
TRT Risks & Rewards: Your Testosterone Replacement Therapy Questions Answered
In this highly requested AMA, Dr. Gabrielle Lyon addresses the most critical questions surrounding male hormone health. Dr. Lyon tackles the fear, stigma, and misinformation surrounding Testosterone Replacement Therapy (TRT), revealing why a low testosterone level is a major predictor of serious health issues like heart disease, bone fracture, and obesity.
She breaks down the current medical consensus on TRT, the risks of replacement, the truth about dosing, and what every man over 40 needs to know about their hormone health. This is a must-watch to separate the bodybuilding myths from the medical facts.
Chapter Markers
The Cancer Scare That Taught Jeremy Miner What Really Matters
In this powerful episode, Dr. Gabrielle Lyon sits down with legendary sales expert and entrepreneur Jeremy Miner to discuss the foundation of success. Jeremy, the founder of Seventh Level, reveals the mental frameworks, communication skills, and commitment required to achieve peak performance in any area of life.
Drawing from his own harrowing health scare and decades of experience coaching top performers, Jeremy shares candid insights into what separates the top 1% from everyone else. This conversation is not just about sales—it’s about the psychology of human connection, overcoming fear, and unlocking your full potential to build a mo...
The Future of Prostate Cancer Treatments & Non-Invasive Techniques with Less Side Effects | Dr. Sanjay Mehta
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When you hear the word “radiation,” do you think of cancer, Chernobyl, or an airport scanner? In this powerful episode, Dr. Gabrielle Lyon sits down with Dr. Sanjay Mehta, a radiation oncologist, to completely redefine your understanding of radiation as a tool for medicine.
Dr. Mehta reveals how modern technology has...
A Parent's Guide to Vaccines & Obesity: Protecting Your Child in a Confusing World | Dr. Joel Gator
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Description
In this episode, Dr. Gabrielle Lyon sits down with pediatrician Dr. Joel Gator Warsh to confront the most concerning trends in children's health. Dr. Warsh, author of A Shot and a Hard Place, reveals the staggering rise of chronic disease and autism in children, arguing that it's a crisis that...
The TRUTH About Makeup, Sunscreen and Skin Cancer | Teo Soleymani
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In this episode, Dr. Gabrielle Lyon sits down with Dr. Teo Soleymani, a fellowship-trained skin cancer surgeon and dermatologist, to cut through the noise of the skincare industry. They discuss everything from viral trends like "glass skin" to the science behind hormones, sun protection, and the lifestyle factors that truly determine your skin's health and longevity.
Dr. Teo Soleymani debunks common myths and provides actionable, no-nonsense advice on what to use—and what to avoid—to buil...
Why Navy SEALs Aren't Scared Like Everyone Else | Rich Diviney
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In this powerful episode, Dr. Gabrielle Lyon sits down with former Navy SEAL Commander and author, Rich Diviney, to break down what it takes to thrive under extreme pressure. Rich, author of "The Attributes and Mastering Uncertainty", reveals the psychology of elite performance, explaining why true toughness has less to do with physical strength and more to do with your mental attributes.
He shares candid insights into the realities of SEAL training, the mental tools used...
The Truth About Hormones: Why Every Woman Should Consider Menopause Therapy
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In this episode, I sit down with nutritional physiologist and friend Nick Barringer, PhD, to tackle a crucial, yet often misunderstood, topic: women's hormonal health. We expose the devastating impact of the Women's Health Initiative study and why millions of women are left untreated for menopause symptoms, leading to an increased risk of issues like osteoporosis and Alzheimer's.
This is a no-nonsense guide for every woman, regardless of age, who wants to understand her hormones and...
