Physionic
I translate health studies for the public - from 'the macro to the micro'.
Dr. Mason: Fiber’s Health Benefits are Built on FLAWED Research!
*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]*Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy*JOIN THE COMMUNITY*Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2*EMAIL LIST*1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6*HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Created with Biorender0:00 - Introduction1:09 - No Good Research on Health Effects of Fiber5:21 - This is what we Need!8:08 - Whoops.. Hypocrisy? 12:50 - Main PointsReferences [1] Park Y, Subar AF, Hollenbeck A, Schatzkin A. Diet...
Aging Genes can be Turned Off, if you do This Regularly
*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]*Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy*JOIN THE COMMUNITY*Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2*EMAIL LIST*1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6*HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Created with Biorender0:00 - Introduction0:48 - Freezing Aging through Exercise4:18 - The Exercise Methylome7:02 - A Bit Gene CrazyReferences[Funding/Conflicts are provided in the free article (found in the email list and Physionic Comm...
Berberine: A Powerful New Metabolic Mechanism Discovered!
*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]*Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy*JOIN THE COMMUNITY*Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2*EMAIL LIST*1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6*HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Created with Biorender0:00 - Introduction0:15 - The Classics1:57 - What’s the News?6:04 - BerberineReferences [Funding/Conflicts are provided in the free article (found in the email list and Physionic Community Article Library)][1] Dong H, Wan...
‘They Lied about High LDL!’ - The Corrupt Science behind Heart Disease
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Glycine Restriction for Cancer, Berberine against Colorectal Cancer, and More
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0:00 - Introduction4:43 - Be...
Collagen for Skin 'Debunked, Non-Nutritive Sweeteners on Cognitive Decline, Seed Oils, and More
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0:00 - Introduction
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A Deep Dive on NAD+ and Longevity, Ft. Rimon from Wellness Messiah
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0:00 - Introduction
1:18 - What is NAD+...
Age Reversing Antibodies, Glycine and Longevity, Ergothioneine and Mitochondria, and More
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Reversing Heart Disease, Creatine on Kidney Health, 5 Life Extending Habits, and More
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Oreos lowering Blood Cholesterol, Science Communication, Mechanisms of Heart Disease, Ft. Dr. Norwitz, Dave Feldman
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Dr. Brad Stanfield: A Discussion of Supplements for Longevity and Health
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Reconsidering Aging, Muscle Growth, Niacin Supplementation, Your Questions, and More
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Carnivore Diet, LDL Cholesterol, Fasting & Inflammation, Taurine on Longevity, and much more...
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Table of Content
0:00 - Introduction
05:18 - Carnivore Diet
34:39 - LDL Cholesterol & Heart Disease
1:00:11 - Taurine on Longevity & Health
1:13:04 - One Meal a Day - Context Matters
1:22:27 - Fiber - Good or Bad? Mixed Reviews...
1:38:10 - Cancer is a Metabolic Disease?
2:07:10 - Fa...
Insulin on Fat Loss, GlyNAC for Anti-Aging, The Physionic Dream.
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0:00 – Introduction.
5:30 – Toxic Acrylamides in Cof...
Removing my John Campbell Video, High Intensity Health, Sweeteners break your Fast?, and More.
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0:00 - Introduction.
3:00 - Dr. John Campbell, High Intensity Health.
39:40 - Nutrition Gurus.
53:00 - My Investigation on Non-Nutritive Sweeteners.
1:03:05 - Improving the 'Detailed Study Analyses'.
1:09:53 - Sweeteners break your Fast?
1:14:23 - Alt...
My High Blood Pressure Experience; Plastics impact on Insulin Resistance.
Hi, in this episode, I cover a bunch of topics from my experience at the doctor, my own hypocrisy, some things I learned from you, and finally - the main topic of discussion: Insulin resistance and how plastics (phthalates) affect it. Oh, and if you're on Spotify or YouTube, it's now a video podcast, as well!
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Issues with Nutrition Documentaries; Caffeine and Performance - They Don't Always Mix.
Hi folks, in this episode I unintentionally discussed two topics. One, I planned on discussing, which was caffeine and it's performance effects in weight lifting and endurance. However, because I woke myself up to a nutrition documentary that I watched for 20 minutes or so before recording, I felt I had to get some things off my chest related to the second topic - nutrition documentaries. So, you have the distinct pleasure (or dismay) of listening to me ramble on both, but I hope that either way you learn something of use, especially related to caffeine.
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Nutrition & Pharmaceutical Therapies: Fat related Cancers
In this episode, the first of a more relaxed, long form podcast style, we're going to dive into how fat relates to cancers - the mechanisms, but beyond that, the different therapies employed by pharmaceuticals, along with the use of nutrition to combat certain cancers.
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Let's Change how We do Things Here.
I think you'd be better served if we change how we do things on the Physionic Podcast.
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Carbohydrates slow Metabolism and Mitochondrial Breathing.
In this episode, I'm going to begin the explanation as to what effects carbohydrates have on our metabolism, and one potential effect in our mitochondria.
Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs34%5D-a-high-carbohydrate-diet-lowers-the-rate-of-adipose-tissue-mitochondrial-respiration
Video: https://www.youtube.com/watch?v=7uBHNUSI6hI
Previous Video on Carbs and Metabolism: https://www.youtube.com/watch?v=xn8VJzGCK5U&t=2s
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An Exception to the Insulin Sensitivity Effects of Saturated Fat [Study 31]
In this episode, we'll discuss a potential exception to the negative results on insulin sensitivity we've been discussing with the exposure to saturated fat.
Study, Notes, & Amendments: https://www.physionic.org/examine/%5B31%5D-palmitate-acutely-induces-insulin-resistance-in-isolated-muscle-from-obese-but-not-lean-humans
Video: https://youtu.be/ldUBG4-EJDo
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Mitochondria & Diabetes: How Nutrition Connects the Two. [Study 32]
Hi all, in this episode, I'm going to describe to you how your nutrition, generally, affects your mitochondria in diabetes specific cells and how long term habits in nutrition can lead to diabetes (type 2). Enjoy.
Video Version: https://youtu.be/x6EOhTzVKsE
Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs32%5D-mitochondrial-dynamics-in-the-regulation-of-nutrient-utilization-and-energy-expenditure
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Your Nutrition affects your Mitochondria (Fasting vs Overconsumption) [Study 32]
In this episode, we'll be diving into two ways your mitochondria change their "behavior" to the exposure to different nutrition situations (high vs low nutrient presence).
Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs32%5D-mitochondrial-dynamics-in-the-regulation-of-nutrient-utilization-and-energy-expenditure
Video: https://www.youtube.com/watch?v=KQBmtzT4VTU
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Saturated vs Unsaturated Fats: One is Worse for Insulin Resistance [Study 30]
In this episode, we'll be going over a new study that wanted to find out the effects a saturated fat heavy consumption would have on insulin resistance and signaling against an unsaturated fat heavy consumption.
Video: https://youtu.be/QfII7CANt14
Study: https://www.physionic.org/examine/%5Bs30%5D-dietary-palmitate-and-oleate-differently-modulate-insulin-sensitivity-in-human-skeletal-muscle
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Unsaturated Fat to the Rescue: Insulin Signaling and Mitochondrial Health [Study 28]
In this episode, we continue our quest for understanding the effect saturated fats have on muscle insulin signaling and mitochondrial health - however, beyond that, we'll be looking at how unsaturated fats may protect against the deleterious effects of saturated fat? Let's see..
Study, Notes, & Amendments: https://www.physionic.org/examine/%5Bs28%5D-different-effects-of-oleate-vs.-palmitate-on-mitochondrial-function%2C-apoptosis%2C-and-insulin-signaling-in-l6-skeletal-muscle-cells%3A-role-of-oxidative-stress-
Video: https://youtu.be/TiO16KoH0Fs
Study Title: Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress. Larysa Yuzefovych
Saturated Fat - Friend or Foe for Insulin Sensitivity and Mitochondrial Function? [Study 27]
In this episode, I'm kicking off a new format that's more tailored to the podcast listeners, so there's less need to head to the video versions of the podcast to understand half of what I'm talking about. In this episode, we'll be discussing saturated fat (palmitate) and it's effects in relation to insulin signaling in muscle cells, as well as mitochondrial function. What are the effects? What are the implications?
Video: https://youtu.be/zMkV91E2Bic
Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249685/
Body Fat is lost from THIS - NOT HORMONES
In this episode, I attempt to make sense of calories in vs out and reconcile that with the hormone argument for fat loss.
Video Podcast: https://youtu.be/x1ZjjDzCdc0
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THIS is how Mitochondria DESTROY your Cells.
Mitochondria have a dark side, find out how.
Video Podcast: https://www.youtube.com/watch?v=HPx7cv1I7eU
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Long Term Effects from Fat Loss - Hormones, Weight Regain? [Study Breakdown]
In this podcast, we look at a study that investigates how weight loss affects hormones and long term weight regain - is the deck stacked against you?
Study: https://www.nejm.org/doi/full/10.1056/nejmoa1105816
Video Podcast: https://youtu.be/-t5d0S5MRwE
0:00 - Introduction
2:47 - Study Design
6:58 - Weight Loss & Weight Regain Results
9:45 - Long Term Hormonal Changes from Weight Loss
34:12 - Conclusions/Take Aways
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Does Intermittent Fasting, WITHOUT WEIGHT LOSS, improve your Health? [Study Breakdown]
How does intermittent fasting affect your health, even when you do not lose weight with it? Let's find out.
Study: https://pubmed.ncbi.nlm.nih.gov/29754952/#:~:text=Men%20with%20Prediabetes-,Early%20Time%2DRestricted%20Feeding%20Improves%20Insulin%20Sensitivity%2C%20Blood%20Pressure%2C,Cell%20Metab.
Video Podcast: https://youtu.be/1t0HUSlFNiQ
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You asked for it: My Lifetime Workout Routine, Health Habits, and Supplements
Title says it all...
Video Podcast: https://youtu.be/u4XirePJKfg
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Sirtuins, Mitochondria, and Insulin Resistance
In this episode, we'll be discussing how sirtuins play their role in mitochondrial health and insulin resistance.
Scientific Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432223/
Video Podcast: https://youtu.be/M9INrzrfsu4
0:00 - Introduction
3:10 - Diabetes Background
8:30 - Mitochondria Background
13:33 - Mitochondria & Insulin Resistance
20:33 - Sirtuins
43:40 - Conclusions/Take Aways
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S...
Creatine on Brain Health; Supplementation & an Alternative?
In this episode, I summarize the content from a brand new scientific review that discusses the difference between creatine supplementation for the brain vs the rest of the body, as well as a possible alternative.
Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916590/
Video Podcast: https://youtu.be/gltKZA6JQr0
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Compensation Theory: Why We should Stop Outrunning our Fat
In this episode, I cover a study sent to me by a subscriber wherein the researchers discuss a new model for understanding metabolism through their self titled 'Compensation Hypothesis'.
Study: https://www.sciencedirect.com/science/article/pii/S0960982221011209
Video Podcast: https://youtu.be/O7TY-HMZkKA
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Does your metabolism decline after 30?
In this podcast, I'll be detailing a brand new study deeply investigating the decline in metabolism with age.
Study: https://science.sciencemag.org/content/373/6556/808
Video Podcast: https://youtu.be/cXHxl8dPqG0
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Is Keto Right for Women's Health? [2 Studies]
In this episode, we'll dive into two very similar studies trying to distinguish the effect of the ketogenic diet on cholesterol, blood sugar, insulin, and blood fats (triglycerides).
Video Podcast: https://youtu.be/yx2OuoMZBFg
Study A: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001988/pdf/nutrients-13-00814.pdf
Study B: https://pubmed.ncbi.nlm.nih.gov/12949361/
0:00 - Introduction
3:40 - Study Design
12:18 - Keto on Cholesterol
20:07 - Keto on Blood Sugar & Insulin
22:25 - Keto on Triglycerides
24:05 - Discussing the Results
37:48 - Conclusions/Take Aways
...
16/8 Intermittent Fasting, without Calorie Counting, on Weight & Health
In this episode, we'll dissect a study wherein the researchers attempt to find out how an unrestricted intermittent fasting protocol works for overweight individuals in aspects of weight, muscle, metabolism, and cardiovascular outcomes like cholesterol, blood sugar, insulin, and so on.
Video Podcast: https://youtu.be/TjEKr7ysbfI
Study: https://pubmed.ncbi.nlm.nih.gov/32986097/
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Questions & Answers: Protein Threshold, Origin of CoVID, Protein on Lifespan, and More.
This week, I return by simply answering questions you guys sent me on Instagram and YouTube.
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0:00 - Introduction
2:35...
Protein for Optimal Muscle Growth: Type, Timing, Amount, and More
In this episode, I cover a scientific review on the literature of protein for muscle growth. We'll be covering protein total amount, timing, type, differences in men and women, aging, and more. Enjoy.
Video Podcast: https://youtu.be/7h-kLKmknEo
Scientific Review: https://link.springer.com/article/10.1007/s40279-019-01053-5
MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING
- 'Understanding Creatine' Book: https://bit.ly/31GxkSN
- Hire Me: https://bit.ly/3dmUl2H
- Content Requests: https://bit.ly/2QOVHLX
SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE]
...
Elevated Blood Fats Change our Mitochondria Behavior & Autophagy
In this episode, we investigate how elevated blood fats change how our mitochondria "behave" and its affect on autophagy.
Video Podcast: https://youtu.be/g6JJzVkYM7I
Study: https://www.sciencedirect.com/science/article/abs/pii/S0026049521001037
MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING
- 'Understanding Creatine' Book: https://bit.ly/31GxkSN
- Hire Me: https://bit.ly/3dmUl2H
- Content Requests: https://bit.ly/2QOVHLX
SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE]
- Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i
- Facebook (Physionic): http...
