The VPZD Show

We're trying to become better listeners, SO PREPARE FOR SOME SHOUTING 🤭 Originally streamed ⁠LIVE on YouTube⁠! (#41)

We cover the new pancreatic cancer drug daraxonrasib and its rash side effect, survival benefit, and cost; what makes pancreatic cancer especially deadly; Vinay’s clinical background across hematology and oncology; how mechanistically cancer actually kills; the challenge of finding good podcast guests and why authenticity matters more than plugging a product; vaccine mandates and the difference between individual versus population-level benefit; the USPSTF’s recent upheaval and the challenge of evidence-based guidelines on contested topics like depression screening, mammograms, and prostate ca...

Yeah it's been over a year but you can't keep a couple of handsome brown guys apart forever 😎 A BRAND NEW VPZD EPISODE, originally streamed LIVE on YouTube! (#40)

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We're back, just cuz we had dinner and felt like a live nightcap. Enjoy!

Watch the originally live YouTube video here.

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Another live episode, we touch on a BUNCH of stuff, including Trump's transition, possible FDA appointments, RFK Jr., letters we've gotten about reproductive rights, was Harris or her team afraid to have her go on Rogan, a deep dive into COVID infection fatality rate and what to do about vaccines, and MUCH more. Watch the video version here.

Subscribe to The VPZD Show on your favorite podcast app. Check out VP's Substack Vinay Prasad's Observations and Thoughts as well as Sensible Medicine. Here's all our previous episodes together.

More...

Regardless of your political leanings, this live podcast WILL traumatize you 😻. 

Election reactions, media polarization, what this might mean for healthcare and WAY more than you cared to hear about Peyronie’s disease 🍆🤓. Watch the video version here.

Subscribe to The VPZD Show on your favorite podcast app. Check out VP's Substack Vinay Prasad's Observations and Thoughts as well as Sensible Medicine. Here's all our previous episodes together.

More on Vinay.

More on Zubin.

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In this episode we discuss Joe Rogan/Trump Interview insights, the ‘science’ of polling, irrational COVID policies, erosion of trust in the medical establishment, the dangers of public health dogma, Trump Derangement Syndrome™️, reflections on the US political system, Zubin’s TikTok verification drama, what creates successful social media reach, TikTok’s cringey docs, the impact of shame on medical practice and education, Rogan’s fixation on physical fitness, why Yoga kicks ass, Vinay’s literary review of Elena Ferrante's Neapolitan series, and Zubin’s personal experience with psychedelics (watch THAT video here).

Video version of this ep...

Former New York public health official Jay Varma's hypocritical sex parties during COVID, why we refuse to talk to most reporters, VP’s take on the new schizophrenia drug, the 10 year anniversary of VP’s PARADIGM-HF heart failure drug trial smackdown, how much an MD/PhD with 100 years of training makes when they finally finish school, Marty’s new book, a Stanford and Emory conference where VP is speaking on public health controversies, and much more!

Subscribe to The VPZD Show on your favorite podcast app. Check out VP's Substack Vinay Prasad's Observations and Though...

Marty's in tha' house to rap about his new book, out Sept. 17th! Blind Spots: When Medicine Gets It Wrong, and What It Means for Our Health. Video version here.

Subscribe to The VPZD Show on your favorite podcast app. Check out VP's Substack Vinay Prasad's Observations and Thoughts as well as Sensible Medicine. Here's all our previous episodes together.

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The three horseman of the apocalypse are BACK! We talk Marty’s new book, CVS as a PBM and the effect on independent community pharmacies, Biden’s medicare drug price negotiations, media health reporting biases, COVID and testing rules, Paxlovid efficacy, the media and lab leak theory, garbage research and health equity, lab leak vs. wet market, medical education is broken and what to do about it, why the med school curriculum is crap, how to fix medical conferences, why debate in medicine is now taboo, ABMS and medical board exam monopoly, culture of obedience in medicine, and more!

The most epic medical bromance in history is BACK and we've brought our A-game 🔥 Video version here.

Topics covered:

00:00 Intro, WE'RE BACK!

4:02 Zubin's Dad's Passing

30:00 Physician Maintenance of Certification (MOC)

48:18 Chat GPT and Medicine

52:24 Letting DOJ Know About MOC Monopoly

54:04 Colon Cancer Screening

1:04:30 Whole Body MRI Scans

1:12:24 GI Jokes

1:13:57 Masking In Hospitals

1:23:07 Doctors' Attire and Behavior (Professionalism)

1:27:21 What's Up With Braces?

👉 Ain't The Way To Die, including resources on end-of-life planni...

Famous docs who can’t process evidence, prior authorization in healthcare and care variation, private equity and gray areas in medicine, the decline of academic medical centers, indoctrination in education, does Paxlovid actually work in populations that matter and the biases of observational trials, fake twitter medical experts, why hospital maintenance workers have more common sense than healthcare leadership, Cochrane mask review, CDC director masking comments and ivermectin, politics in science and why politicians simply can’t be honest, and more! Video here.

We were both victims of the "tripledemic" and now have Long Cold but we're BACK! In Episode 30 we dive into the recent focus on sudden deaths and cardiac arrest in athletes such as Damar Hamlin and whether vaccine causation can be attributed as many online "experts" insist, Vinay's new myocarditis paper, FDA withholding Moderna human data from advisory committee members during bivalent EUA approval, do medications really "expire" and much more!

Video: https://youtu.be/DOQF2JNZug4

The boys are back in town 🔥. We talk about the future of social media, Elon Musk's Twitter, misinformation policing failures, metabolic health, being your authentic self and more. 

Here's VP's Sensible Medicine article we referenced.

Topics & Timecodes

00:00 Verbal & non-verbal communication, listening & presence

02:43 The future of social media, Zuckerberg, Elon's authenticity, Twitter & the blue checkmark disaster

10:49 Z's alleged 30-millionaire status, calculating net worth, the importance of supporting content & creators you care about

14:54 Sensible Medicine & VP's Misinformation Police article, suppression of ideas vs. presenting a better counter-argument, the far left...

ZD visits VP studios for a broad discussion about colonoscopy, Florida's surgeon general Ladapo and Science magazine, the new oath taken by UMN medical students during their White Coat ceremony, and MUCH more. The only thing missing is VP's signature black leather jacket 🔥

Watch VP's breakdown of the NordICC colo trial here, here, and here. Read UMN's white coat oath and learn more about Ladapo and the Science magazine editorial here.

We discuss firing of the NYU professor who's class was too hard, the problems with screening for medical school admission, Dr. Glauckomflecken's maskless Twitter selfie thing and the nature of virtue signaling, why JEDI aren't woke enough according to Scientific American (cuz eugenics of course), a recent study on personality changes due to the pandemic, CRAZY liberal arts college masking policies, and much more!

VP and ZD celebrate the return of in-person conferences, lament the challenges of continued mandatory masking in healthcare settings, and talk about better ways to get at truth (yeah, I'm kinda phoning in the summary of this dope discussion this time, just listen already 😂 #quietquitting)

Video: https://youtu.be/B7V1RelMXwA

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A Labor Day Special!

CDC recommends bivalent Omicron-specific boosters for everyone, the madness of the CO2 meter crowd, journalism's challenges, mean attending physician comments, the evolution of language, and more!

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The saga of Dr. Leana Wen, omicron-specific boosters for the fall, low uptake for vaccinating kids

How can you determine who is trustworthy when it comes to medical information? Our new project "Sensible Medicine," untangling the complexities of health care reform, angry doctor Covidian tweets with magical thinking and religiosity, the dangers of over-testing and over-treatment with regards to routine blood work, Haidt’s 3 Great Untruths and cognitive distortions, pandemic response effect on true progressives, the consequences of ideological possession, how Vinay reviews the trustworthiness of sources, the difficulties of “debunking”, the monkeypox situation, and much more!

Video: https://youtu.be/jmebULFQWyw

We deep dive into how our tribal divisions influence interpretations of science, ethics, and policy (topic list below).

Here's the Offit interview I mentioned.

Topic List

Stanford medical school commencement ceremony, boosters for 5-11 year olds, Cat COVID, the end of pre-departure screening, VP's Oncology video drama, Twitter addiction and "second selfing," is continual feedback a good thing, San Francisco DA gets recalled, new immunotherapy for colorectal cancer, the importance of palliative care in oncology, and much more!

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We dive into the riddle of gun violence in America, violence against healthcare professionals, public health officials and closing schools, will we need an annual COVID shot and how would we study that, the emergence of monkeypox, and the Depp/Heard trial.

Video: https://youtu.be/9i8cD4j4sQE

We talk with Dr. Rita Redberg (professor of medicine & cardiologist at UCSF) about how very often less is more when it comes to medical care.

We cover cancer screening (PSA, mammograms, blood testing, colonoscopy, CT screening for lung cancer), the utility or lack thereof of genetic testing, medical devices, statins, hypertension guidelines and treatment, and much more. And here's my prior interview with Dr. Redberg.

Video: zdoggmd.com/less-is-more

CDC data collection, hepatitis in kids, Johnson & Johnson vaccine limited use, more on physician "influencers," the Roe V. Wade Supreme Court leaked draft decision, surprise medical billing, a nutty Twitter COVID story, seroprevalence of COVID in children, the White House Correspondents Dinner, annual COVID shots, Omicron's mortality, the "Pfizer documents" and more!

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Elon Musk buys Twitter and what that may mean, group mind and the threat of nuclear holocaust, the conundrum of "physician influencers" on social media, Moderna's push to get EUA for it's vaccine in kids younger than 5, the Stanford nurses go on strike, challenges in academic medicine, should people in healthcare forge their OWN path, and much more! The Dr. Risa Hoshino substack piece: https://sarahburwick.substack.com/p/who-is-risa-hoshino.

We dive DEEP into all the things in this rare in-person video episode of The VPZD Show. And VP's lookin' pretty fly for a brown guy in that black jacket 🔥

We talk Elon Musk & Twitter, Bill Maher & medical humility, CNN's Dr. Leana Wen and her recent 360, China lockdowns, declines in teen mental health, kids cloth masking, booster science, Dr. Ashish Jha, the nature of audience capture, the value of authenticity, imposter syndrome, and much more. As promised, here's our first in-person interview from 2020; you can find all our episodes here.

Full transcript and video: https://zdog...

In this episode: Ivermectin, the latest Twitter absurdities, vacation without COVID, Will Smith, why medical conferences SUCK, NYC's toddler mask policy, why so many academics leave for pharma, that 4th dose, and more! Full transcript: https://zdoggmd.com/podcasting/vpzd-15/

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We're back! In this episode we talk: dumb COVID policies, mask shaming on both sides, Kyrie Irving vaccine controversy, worshipping Lord Zero COVID (Hong Kong and elsewhere), press coverage biases, a FOURTH booster shot, ethical considerations around pharma not providing meds to Russia, dumber college COVID policies, the deal with early treatments, Ash Jha and John Ioannidis, and the James Webb telescope and STEM inspiration. Full transcript: https://zdoggmd.com/podcasting/vpzd-14/

In this episode we discuss:

-Dr. Z's Twitter "bullying" of the California Academy of Sciences kids' museum over their restrictive booster/testing entrance policy (and why Z deleted Twitter at last). Read about it in MedPage Today.

-New data on the efficacy (or lack thereof) of Pfizer's vaccine in the 5-11 year old population and what this means for policy.

-Why public health may need controls placed on it in the future to avoid restrictive policies that lack evidence (see also: Vinay's Substack article).

-Dr. Z debunks some antivaccine claims about a...

In this episode: The badges of tribal identity for COVID thesis/antithesis tribes, "deplatforming" scientists and the conditioning of young people, liberals and conservatives trading places, aiming for post-cynical discourse, the perils of comparing nations' COVID outcomes, and the FDA's crazy

The docs talk about Vinay getting a booster or losing his job, why we continue to mask children, Pfizer's vaccine dance with the FDA around children younger than 5, the wisdom of trying to cancel Joe Rogan, Spotify's "trusted" COVID disclaimer, and the urgency of getting kids back to a normal.

Here's the Urgency Of Normal site that Vinay referenced in the show.

Full transcript: https://zdoggmd.com/podcasting/vpzd-11/

Vinay and Z dive deep on the latest censored antithesis hero while trying to make sense of sense-making in general. Here's Vinay's piece on this in Unherd.

And here's the Rebel Wisdom episode on sense-making that I referenced. Full transcript: https://zdoggmd.com/podcasting/vpzd-10/

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We dive into Dr. Paul Offit's Atlantic piece on boosting teens, the nature of the CDC's apparent schizophrenia, the long term effects on the "pandemic generation," and how Omicron is causing all our prior policy dominoes to fall. Also: FUNNY TWEETS 🤓

Here's Dr. Paul Offit's Atlantic article we mentioned. Full transcript: https://zdoggmd.com/podcasting/vpzd-9/

Learn more abo...

In this Omi-sode:

1) Can omicron be mitigated AT ALL? The Bay Area experience currently.

2) Novak Djokovic and the COVID vaccine

3) Covidiots vs. Covidians, where is the Alt-Middle? Rogan's role.

4) The dumbest tweets of 2021

5) Who was most right about COVID policy?

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Many questions addressed on this last episode of 2021!

This week we dive into Dr. Z's personal booster decision, do vaccines reduce transmission in setting of variants like Omicron, Joe Rogan’s interview with Dr. Peter McCullough , the hypocrisy of physicians who demand masks and distancing and then do the opposite themselves, medical students speaking out against distance learning, new myocarditis trial data with implications for Moderna and spacing vaccines in general, meditation stuff, the problem with virtue signaling, the number needed to boot with vaccine passports to prevent 1 transmission, and MUCH MORE.

In this episode we dive into some emails Dr. Z received about hospital COVID policies and medical education (and how our leaders are screwing up), the problem with mandates in healthcare, and strongly negative feedback for us from a critical care nurse on the front lines about our vaccine messaging. In the news, we react to NPR’s piece saying Trump voters more likely to die of COVID, what is the nature of “misinformation” on both sides of the political spectrum, the challenges of quantitative journalism, the German study on kids and COVID risk, Pfizer omicron booster press release and su...

Dr. Marty Makary joins the fray for a science & reason SMACKDOWN 🔥 How many Omicrons does this register on the media fear-o-meter? 

Check out all our shows with MedPage today editor-in-chief Dr. Marty Makary here. And all our shows with UCSF hematologist-oncologist Dr. Vinay Prasad here. And our new joint podcast, The VPZD Show, here. And here's the video version of this interview!

Topics & Timecodes:

0:00 Intro

2:17 Boosters for All?

8:47 Young people + Covid, flawed CDC studies?

12:45 Natural immunity, Myocarditis, population risk vs. benefit

21:15 The narrative of simplicity and...

For the week ending Dec. 1st 2021, VP and ZD dive into Dr. Oz running for the senate, the Omicron gambit, dumb travel restrictions, what the heck with boosters 4 all, poor quality science and biased scientific oversight, and MUCH more!

Here's all our other shows featuring VP.

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Dr. Z and Dr. Vinay Prasad get unfiltered about the NY Times recommendations for a safe COVID Thanksgiving, whether Dr. Fauci should quit, and whether a healthy young person should get a Moderna booster, and more!

Here's all our other video episodes featuring VP.

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