The a16z Show
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
The New Rules of Media | Marc Andreessen & Ben Horowitz
Recorded live at the New Media Summit, Marc Andreessen, Ben Horowitz, Erik Torenberg, and Gaby Goldberg discuss how media, communication, and influence are changing in the internet era.
The conversation explores the shift from legacy media to creator-led platforms, why authenticity has become a competitive advantage, and how founders can build audiences by communicating directly with customers, employees, and the public. They discuss podcasts, social media, storytelling, corporate communications, and the changing relationship between companies, journalists, and audiences.
Along the way, they examine how founders can develop a public voice, why some leaders become influential...
The Fintech Playbook for Latin America
Angela Strange and Gabriel Vásquez speak with Addi founder and CEO Santiago Suárez about building one of Latin America's largest financial platforms.
What began as a buy now, pay later product has evolved into a broader ecosystem spanning payments, commerce, logistics, and now banking. Serving millions of consumers and tens of thousands of merchants, Addi sits at the intersection of financial services and commerce in Colombia.
The conversation covers building in Latin America, lessons from scaling through multiple market cycles, the importance of technology infrastructure, and why Suárez believes financial inclusion and eco...
Jack Altman on Product-Market Fit
Jack Altman joins Speedrun to discuss product-market fit, customer feedback, hiring, fundraising, and the realities of building an enduring company.
Drawing on his experience building Lattice from startup to multi-billion-dollar company, Altman explains how founders should think about customer requests, when to pivot, and why some of the hardest decisions come from balancing conviction with market feedback. He shares lessons from the early days of Lattice, including finding product-market fit, building a sales motion, hiring the first employees, and navigating the tradeoffs that emerge as companies scale.
The conversation also covers fundraising, co-founder relationships, startup...
AI, Design, and the Power of Open Models
Yoko Li and Justine Moore speak with Ideogram founder and CEO Mohammad Norouzi about image generation models, design workflows, and the evolving relationship between AI and creative work.
The conversation covers Ideogram's decision to release an open-weight model, the challenges of generating text and layouts within images, and why controllability has become an increasingly important area of research. They discuss prompting, customization, editing, and the tradeoffs between general-purpose models and systems optimized for specific creative tasks.
Along the way, Norouzi shares his views on open-source AI, design tools, agentic workflows, and how image generation models...
Samo Burja on Growth, Energy, and AI
Theo Jaffee speaks with Samo Burja, founder of Bismarck Analysis, about AI, industrial capacity, economic growth, and the institutions that shape civilization.
The conversation explores how AI’s demand for compute, energy, and infrastructure could trigger a new wave of industrial expansion, benefiting sectors far beyond technology. Burja argues that AI is not just a software story but a demand shock that will ripple through energy, manufacturing, construction, and global supply chains.
They also discuss China and the United States, demographic decline, fertility, state capacity, welfare systems, and the political economy of automation. Along the wa...
Designing the Physical World with AI
Erin Price-Wright speaks with Alex Modon, cofounder and CEO at Unlimited Industries, and Davide Asnaghi, CEO at Diode Computers, about how AI is moving from software into the physical world. They discuss automating construction and electronics design, using code and simulation to model real-world systems, and how incentives and manufacturing constraints shape adoption. They also examine what it takes to scale infrastructure, reduce build times, and unlock more abundant industrial capacity in the United States.
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AI, Growth, and the Future of Healthcare | Anish Acharya & Sachin Jain
SCAN Health Plan CEO Sachin Jain speaks with a16z General Partner Anish Acharya about AI, healthcare, and what it takes for established organizations to adapt during periods of technological change.
The conversation explores how AI is reshaping work, customer experience, software development, and organizational structure. Acharya argues that artificial intelligence is not simply another productivity tool, but a fundamentally new technology capable of performing work on behalf of people and organizations.
They discuss AI adoption inside large enterprises, the future of customer support, software development, healthcare operations, and why curiosity, experimentation, and ambition may...
Tyler Cowen & Alex Tabarrok on AI, Jobs, and Economic Growth
Wyatt Thomson of OpenAI speaks with economists Tyler Cowen and Alex Tabarrok about AI, labor markets, and the future of economic growth.
The conversation explores one of the most common fears surrounding AI: that increasingly capable systems will eliminate jobs. Cowen and Tabarrok argue instead that economic growth remains the key variable. Throughout history, productivity-enhancing technologies have transformed work, created new industries, and expanded living standards, even as they disrupted existing jobs and institutions.
They discuss automation, comparative advantage, inequality, education, healthcare, energy, and the kinds of work that may become more valuable in an...
Building Search for AI Agents with Exa CEO Will Bryk
Sarah Wang speaks with Exa cofounder and CEO Will Bryk about building search infrastructure for the AI era.
The conversation covers Exa’s origins, why traditional search engines were not designed for AI agents, and how search changes when the user is no longer a human but an autonomous system. They discuss retrieval, agent workflows, coding agents, data access, and why search may become a foundational layer for the emerging agent economy.
Along the way, Bryk shares his views on AI-native products, the future of information discovery, and why some of the most important problems in...
AI Agents and the Fight for Customer Data
Martin Casado speaks with George Fraser, cofounder and CEO of Fivetran, about the future of data infrastructure in the age of AI.
The conversation covers Fivetran’s merger with dbt, the changing role of data platforms, and why Fraser believes many companies are overestimating the threat AI poses to enterprise software. They discuss open data access, the backlash against AI agents accessing systems of record, and why businesses still need centralized data foundations even as agent-based workflows become more common.
Along the way, Fraser shares his views on data gravity, coding agents, enterprise AI adoption, an...
AI Eats the World? A Reality Check with Benedict Evans
Erik Torenberg speaks with tech analyst Benedict Evans about the current state of AI, what has changed over the past year, and which questions remain unanswered.
The conversation covers coding agents, foundation models, AI infrastructure spending, software economics, and the tension between today's AI excitement and the long-term realities of technology adoption. Evans discusses why coding has emerged as AI's first breakout use case, how previous platform shifts can help frame the current moment, and why many of the most important questions about AI remain unresolved.
Along the way, they explore the future of software...
Balaji and Steven Glinert on Network States, Supply Chains, and Allied Coalition Strategy
Theo Jaffee and Sophia Puccini speak with Balaji Srinivasan and Steven Glinert about the shifting balance of power between nations, networks, and technology.
The conversation covers China’s industrial rise, America’s manufacturing challenges, the role of alliances in a multipolar world, and whether the internet is becoming a political force independent of traditional nation states. They discuss supply chains, technological sovereignty, decentralization, and competing visions for the future global order.
Along the way, Balaji outlines ideas from the Network State and Network School, while both guests debate how technology, economics, and political power may evol...
Steven Sinofsky on Apple at 50, Microsoft, and the Future of Computing
Theo Jaffee speaks with Steven Sinofsky about Apple’s 50th anniversary and the evolution of personal computing over the last four decades.
Drawing on his experience helping lead Microsoft through the Windows era, Sinofsky reflects on the cultural differences between Apple and Microsoft, the rise of the Mac, the history of Windows, and how product design, hardware integration, and software platforms shaped the modern technology industry.
They also discuss the Apple Vision Pro, the new MacBook Neo, gaming, operating systems, and why some technology cycles seem to repeat themselves. Along the way, Sinofsky shares lessons fr...
Building AI Agents for Enterprise Operations
Anish Acharya and Olivia Moore speak with Pablo Palafox and Luis Paarup about the challenges of deploying AI agents in operationally complex industries.
The conversation covers the evolution of voice AI, enterprise workflows, and why logistics became an early proving ground for agent-based systems. They discuss context, coordination, and execution inside large organizations, as well as the role of forward-deployed engineering, enterprise deployment, and what it takes to move AI from experimentation into production.
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Why $1B Exits are Dead
David George, General Partner at a16z, and David Clark, CIO at VenCap, discuss how AI is reshaping venture capital and the technology industry itself. They examine why today’s AI companies are scaling faster than any previous generation of startups, and why the eventual outcomes may be significantly larger than most investors currently expect.
The conversation covers frontier AI models, coding agents, open source competition, data center constraints, and who ultimately captures value in the AI ecosystem. They also discuss what these shifts mean for venture capital itself, including larger company outcomes, faster value creation, and th...
Stablecoins, AI Agents, and The Future of Global Banking
Angela Strange speaks with Dileep Thazhmon, founder and CEO of Jeeves, about building a global financial operating system for enterprises across Latin America using stablecoins and AI.
The conversation covers the challenges of building localized financial infrastructure across 25 countries, from regulation and payments to underwriting and compliance. They also discuss why stablecoin adoption is accelerating in Latin America, and how AI is helping Jeeves scale billions in payment volume while automating underwriting, customer support, reconciliation, and KYB workflows.
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Marc Rowan on Private Markets, Software Repricing, and Capital Allocation
In 1990, Marc Rowan walked out of Drexel with his belongings in a cardboard box. Within a year, Apollo was managing $6 billion.
David Haber speaks with Marc Rowan, Cofounder, CEO, and Chair of Apollo Global Management, about building Apollo into one of the world’s largest alternative asset managers and how private capital is reshaping the global economy.
The conversation covers the rise of private credit, and why Rowan believes private markets are becoming increasingly central to financing the real economy. They also discuss AI, data centers, robotics, and the growing intersection between venture-backed technology companies an...
Robin Hanson on Prediction Markets, Gambling, and the Future of Forecasting
Theo Jaffee and Sophia Puccini speak with economist Robin Hanson about prediction markets, gambling, and why he believes speculative markets are one of the most powerful tools humans have for aggregating information and forecasting outcomes.
The conversation begins with Minnesota’s recent law criminalizing prediction markets before expanding into the broader backlash surrounding platforms like Kalshi and Polymarket. Hanson explains his long-term vision for “decision markets,” where markets could help guide choices made by companies, governments, and even individuals.
Along the way, they discuss sports betting, games and human psychology, futurism, AI, and Hanson’s broader...
Why AI Isn’t Killing SaaS Yet
Originally aired on MTS segment, Monetary Matters, Jack Farley and Max Wiethe speak with Ara Kharazian, Lead Economist at Ramp, about what real business spending data says about AI adoption, why the “SaaSpocalypse” narrative is overblown, and how companies are actually buying and deploying AI tools. They also discuss Anthropic overtaking OpenAI in Ramp’s AI Index, token-based pricing, AI productivity gains, and why many legacy software firms may be more resilient than people expect.
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Hugging Face's Clem Delangue on Open Source AI and the LLM Bubble | MTS Live
Clem Delangue joins MTS to discuss the global open-source AI landscape, the current large language model bubble, and the future of consumer robotics.
Originally aired on MTS, Theo Jaffee and Sofia Puccini speak with Clément Delangue, CEO at Hugging Face, about the global open-source AI race, why he believes the real bubble is in API-based large language models, and how robotics could become the next major interface for AI. They also discuss AI safety, U.S.-China competition, open-weight models, and why Hugging Face became the infrastructure layer for open AI development.
Re...
How Superhuman Took Over Silicon Valley Email
Rahul Vorra is the founder and CEO of Superhuman, the premium email client for power users. He previously built the Gmail plug-in Reportive and sold it to LinkedIn. He began somewhere unexpected though, as a game designer on RuneScape. In this conversation, Rahul breaks down why most founders misunderstand product market fit, why premium can actually hurt your business, and how deliberate constraint can become your biggest advantage.
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Marc Andreessen on AI, California, and the Future of America | Joe Rogan
Marc Andreessen joins Joe Rogan for a conversation on AI, politics, technology, and the future of American society. They discuss how artificial intelligence is rapidly moving from novelty to infrastructure, and why Andreessen believes its long-term impact will be overwhelmingly positive despite growing public fear around automation and surveillance.
The conversation covers the explosion of AI coding tools, the emergence of “AI agents,” and how these systems are already reshaping software development, medicine, and education. Andreessen argues that AI should be understood less as replacement technology and more as a universal layer of cognitive augmentation, giving individuals acce...
Rebuilding The American Shipyard
Erin Price-Wright speaks with Michael Duffey and Dino Mavrookas about what it will take to rebuild the American defense industrial base for a new era of competition. As production capacity becomes a central constraint, they outline how the system must shift toward speed, scale, and modern manufacturing.
The conversation covers the role of autonomy in both defense systems and industrial processes, and how new approaches to design, labor, and production can dramatically reduce cost and complexity. Mavrookas explains how building for software and autonomy enables entirely new classes of platforms, while Duffey emphasizes the need for structural c...
The Plan to Make American Crime Obsolete
David Ulevitch speaks with Col. Jeffrey Glover and Rahul Sidhu about how AI, drones, and sensor networks are reshaping public safety and what it takes to bring new technology into law enforcement at scale. As departments face staffing shortages, burnout, and rising complexity, they examine how the right tools can make officers more effective, safer, and better supported.
The conversation covers how drone-as-first-responder programs are changing the speed and safety of emergency response, from high-risk warrant service to Amber Alert pursuits. Glover describes how Arizona DPS is building a full technology ecosystem around its officers, including body-worn...
Vitalik Buterin on Human Agency in the AI Era
Sophia Dew and Binji Pande speak with Vitalik Buterin about technology, human agency, and how the internet is changing the way people think, build, and relate to the world around them. Drawing from his writings and personal reflections, Buterin discusses how his worldview has evolved over the last decade, from creating Ethereum as a teenager to thinking more deeply about the social and philosophical implications of technology today.
The conversation explores the idea of “sanctuary technology,” systems that provide safety and coordination without removing individual freedom or agency. They also discuss the changing relationship between humans and AI...
Ben Horowitz - "Your ONLY job is Right Product, Right Time"
Ben Horowitz shares lessons from building and scaling companies, drawing on his experience as a founder and CEO. He explains why a founder’s primary responsibility comes down to one thing: delivering the right product at the right time.
The conversation covers how strategy actually develops in practice, why a company’s story is inseparable from its strategy, and how founders should think about hiring, fundraising, and decision-making in fast-changing environments. Horowitz also discusses how AI is reshaping teams, the increasing importance of creativity and relationships, and why roles may evolve toward more generalist “builders.”
He also...
Energy, Minerals, and the Physical Stack Behind AI
Erin Price-Wright speaks with Turner Caldwell and Drew Baglino about what it will take to close America's critical minerals gap and modernize the power infrastructure that underpins the AI economy. With the US more than 50 years behind China in critical mineral supply and grid infrastructure built on systems designed a century ago, they examine where the real bottlenecks are and how to move faster.
The conversation covers how automation, reinforcement learning, and vertically integrated operations can compress the timelines for mining and refining, and why co-locating supply chains matters more than labor costs in the race to...
Lloyd Blankfein on Risk, Crisis, and Leadership
David Haber speaks with Lloyd Blankfein, former CEO of Goldman Sachs, about leadership, risk, and navigating moments of extreme uncertainty. Drawing on his experience leading Goldman through the financial crisis, Blankfein shares how organizations can build resilience, make decisions under pressure, and maintain culture while scaling.
They discuss the importance of risk management as both a discipline and a mindset, the difference between being wrong and being reckless, and how great organizations balance taking risk with protecting against it. Blankfein also reflects on Goldman’s partnership culture, how it shaped decision-making and accountability, and what it takes to...
Marc Andreessen on Builder Culture in the Age of AI
Erik Torenberg speaks with Marc Andreessen about the state of AI, media, and the broader cultural and economic shifts shaping the internet. They discuss how narratives around AI, from fear to hype, are influencing public perception, and why real-world usage tells a very different story.
The conversation covers AI’s impact on jobs and productivity, the rise of “AI-native” builders, and why increased capability tends to expand work rather than eliminate it. Andreessen also examines how companies are adapting, from restructuring teams to rethinking roles around more generalist “builders.”
They also explore the changing media landscape...
Ben Horowitz on the Next Technology Era
David Ulevitch speaks with Ben Horowitz about what it means to lead the technology industry at scale, and the responsibilities that come with it. Following the firm’s largest-ever fundraise, they discuss how venture capital, technology, and national strategy are increasingly intertwined.
The conversation covers America’s role in the next technological revolution, from AI to advanced manufacturing, and why maintaining technological leadership is critical not just for economic growth, but for global influence. Horowitz also shares his perspective on working with government, supporting national security innovation, and building systems that give more people the opportunity to cont...
Crypto Fund 5: We Raised $2.2B. Here’s Why.
Robert Hackett speaks with the general partners at a16z crypto about the launch of their fifth crypto fund and the current state of the industry. They reflect on how crypto has evolved from an ideological movement into a more pragmatic, product-focused ecosystem, shaped by real-world use cases and increasing regulatory clarity.
The conversation covers the rise of stablecoins, onchain finance, and new market infrastructure, as well as the growing overlap between crypto and AI. The group also discusses how founders are shifting toward building products that work within existing systems, rather than attempting to replace them...
The New Space Race: NASA, Artemis, and the Race to the Moon
Morgan Brennan speaks with NASA Administrator Jared Isaacman about the next phase of American space exploration and the urgency behind returning to the moon. They discuss the Artemis program, the challenges of cost, speed, and execution, and how a new competitive landscape is reshaping NASA’s priorities.
The conversation covers the role of public-private partnerships, the rise of commercial space companies, and the need to rebuild core capabilities within NASA. Isaacman also outlines how the agency is shifting toward faster iteration, clearer demand signals for industry, and a more focused strategy to compete in what he describes as...
Building Blackstone, Backing Costco, with Tony James
David Haber speaks with Tony James about building enduring firms across multiple eras of finance. From joining DLJ when it was a subscale firm to helping grow Blackstone into one of the largest asset managers in the world, James reflects on the decisions, structures, and cultural principles that enabled long-term success.
They discuss the origins of leveraged buyouts, the evolution of private markets, and how identifying structural opportunities early can create lasting competitive advantage. James also shares lessons from backing companies like Costco, where culture, customer focus, and long-term thinking drove exceptional outcomes.
The conversation...
Sarah Rogers: Free Speech, AI Diplomacy, and What America Owes Its Allies
Katherine Boyle speaks with Sarah Rogers, Under Secretary for Public Diplomacy, about the intersection of AI, free speech, and global information systems. They discuss how major technological shifts, from the printing press to the internet to AI, have reshaped communication and power, and why this moment may be even more consequential.
Recorded at the a16z American Dynamism Summit, the conversation explores the role of public diplomacy in the digital age, the risks of censorship and overregulation, and how governments are approaching AI as both a national security priority and a platform for global influence. Rogers also...
Balaji and Taylor Lorenz on AI and Media
Theo Jaffee speaks with Balaji Srinivasan and Taylor Lorenz about how AI is reshaping media, trust, and online communication. Building on prior public disagreements between the two, the conversation revisits core tensions around media, technology, and power in a rapidly changing information environment.
They discuss the breakdown of traditional information systems, the rise of AI-generated content, and why new models for verifying identity and truth may be necessary. The conversation lays out competing visions for the future of media, from decentralized “webs of trust” and cryptographic verification to the role of journalism, privacy, and public accountability.
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Workday’s Last Workday? AI and the Future of Enterprise Software
Elena Burger speaks with Joe Schmidt, partner on the enterprise team at a16z, about the future of enterprise software in the age of AI. Using Workday as a case study, they discuss why many of today’s most important enterprise systems feel broken, how platform shifts reshape entire categories, and what an AI-native replacement might look like.
The conversation covers the limits of legacy SaaS, why “AI revenue” may be overstated, and how agents could fundamentally change how companies manage workflows, permissions, and internal systems. They also explore why even the most defensible software businesses may now be...
The Shift in Global Drug Development
Theo Jaffee and Gabriel Dickinson speak with Cremieux about China’s rapid rise to the top of global clinical trial output. They discuss the regulatory reforms that accelerated China’s progress, the surge in novel drug development, and what the US would need to change to stay competitive in biomedical innovation.
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John and Patrick Collison on Stripe's Growth, Agent Commerce, and the Future of Software
This interview with Stripe cofounders John and Patrick Collison originally aired on TBPN. They discuss Stripe's 34% growth and new employee tender offer, how agent commerce and stablecoins may require high-throughput blockchains built for millions of transactions per second, and why the economics of software are shifting from mass-produced products to bespoke, on-demand systems cooked fresh at the moment of use.
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Ben Horowitz on Venture Capital and AI
Anjney Midha, founder of AMP PBC, speaks with Ben Horowitz, cofounder of a16z, about how venture capital changed from a small, relationship-driven business into a scalable system for backing new technology companies. They discuss network effects, firm design, leadership, culture, and how AI is reshaping both the capital race and the kinds of companies that can be built now.
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AI Inside the Enterprise
Steven Sinofsky, board partner at a16z, Aaron Levie, CEO of Box, and Martin Casado, general partner at a16z, discuss the reality of AI inside enterprises. They cover the gap between Silicon Valley and the rest of the world, why most AI initiatives fail in large organizations, and how agents, infrastructure, and workflows are evolving beyond the hype.
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