The Empowering Neurologist Podcast

40 Episodes
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By: David Perlmutter

The Empowering Neurologist is an interview series with some of the most exciting thought leaders in the field of health and wellness.

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The Diet Linked to Up to 50% Lower Dementia Risk | Dr. Austin Perlmutter
The Diet Linked to Up to 50% Lower Dementia Risk | Dr. Austin Perlmutter episode artwork
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Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available! Discover how to protect your brain and future health - grab your copy today at ⁠https:/www.braindefenders.com⁠.

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Your food contains far mor...


I Asked AI Actress Tilly Norwood What Happens When AI Becomes Smarter Than Us | E226
I Asked AI Actress Tilly Norwood What Happens When AI Becomes Smarter Than Us | E226 episode artwork
09/17/2026

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Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available! Discover how to protect your brain and future health - grab your copy today at https:/www.braindefenders.com.

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She's neve...


The ALS Case Challenging What Neurology Thought Was Impossible with Dr. M. Marc Abreu | E225
The ALS Case Challenging What Neurology Thought Was Impossible with Dr. M. Marc Abreu | E225 episode artwork
09/15/2026

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Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available! Discover how to protect your brain and future health - g...


Why You Feel Older Than Your Labs Say You Are with Dr. Will Cole | E224
Why You Feel Older Than Your Labs Say You Are with Dr. Will Cole | E224 episode artwork
09/01/2026

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Perlmutter’s newsletter at: www.drperlmutter.com. ✉ 🌱 Thank you to our sponsors:

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Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available! Discover how to protect y...


Why Women’s Brain Fog Gets Dismissed with Dr. Nicole Beurkens & Emma Heming Willis | E223
Why Women’s Brain Fog Gets Dismissed with Dr. Nicole Beurkens & Emma Heming Willis | E223 episode artwork
08/19/2026

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱====Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available! Discover how to protect your brain and future health - grab your copy today at https://drperlmutter.com/books/brain-defenders/.====What if one of the most important windows for protecting women’s brain health happens decades before Alzheimer’s symptoms ever appear?On this episode of The Empowering Neurologist, we explore the growing conversation around women, hormonal transition, and long-term brain health with two guests bringing very different, and dee...


The Hidden Stress Response That's Hijacking Your Brain with Dr. Scott Sherr | E222
The Hidden Stress Response That's Hijacking Your Brain with Dr. Scott Sherr | E222 episode artwork
#222
08/04/2026

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Thank you to our sponsors:EVY - https://www.optoceutics.com/perlmutter and the code perlmutter26 will be auto-applied to your order to get $200 off & free shipping (90 days risk-free). 3x4 Genetics - https://3x4genetics.com/DrPerlmutterfor a special offer when you sign up to decode your genetics and get personalized, science-backed health recommendations.====Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available for pre-order. Discover how to protect your brain and future health - reserve your copy toda...


The Metabolic Switch That Turns Your Brain Against Itself | E219
The Metabolic Switch That Turns Your Brain Against Itself | E219 episode artwork
#219
07/28/2026

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter's newsletter at: www.drperlmutter.com. ✉️🌱====Dr. Perlmutter's groundbreaking new book, Brain Defenders, is now available for pre-order. Discover how to protect your brain and future health - reserve your copy today at https://www.braindefenders.com.What if everything you've been told about Alzheimer's, that it's caused by sticky plaque building up in your brain, is missing the real story? In this episode, Dr. David Perlmutter makes the case that the true driver of neurodegeneration isn't plaque at all. It's your own brain's immune cells turn...


Why Removing Amyloid From the Brain Isn't Enough to Stop Alzheimer's with Dr. Jonathan Fellows | E220
Why Removing Amyloid From the Brain Isn't Enough to Stop Alzheimer's with Dr. Jonathan Fellows | E220 episode artwork
#219
07/23/2026

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Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available for pre-order. Discover how to protect your brain and future health - reserve your...


87% of Parkinson's Cases Have No Genetic Cause: It's in Our Environment with Dr. Ray Dorsey | E219
87% of Parkinson's Cases Have No Genetic Cause: It's in Our Environment with Dr. Ray Dorsey | E219 episode artwork
#219
07/08/2026

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The AI That Caught What Every Doctor Missed — Genome-Powered Medicine Is Here with Dr. Don Brown | E218
The AI That Caught What Every Doctor Missed — Genome-Powered Medicine Is Here with Dr. Don Brown | E218 episode artwork
#218
06/23/2026

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Dr...


Why Your Brain Feels Broken: The Metabolic Truth Behind Burnout and Depression with Dr. Robin Berzin | E217
Why Your Brain Feels Broken: The Metabolic Truth Behind Burnout and Depression with Dr. Robin Berzin | E217 episode artwork
#217
06/09/2026

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱Thank you to our sponsors:EVY - Go to https://www.optoceutics.com/perlmutter to get $200 off & free shipping (90 days risk-free). 3x4 Genetics - https://3x4genetics.com/DrPerlmutterfor a special offer when you sign up to decode your genetics and get personalized, science-backed health recommendations.====Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available for pre-order. Discover how to protect your brain and future health - reserve your copy today at https://www.braindefenders.com.====What if your a...


The Laws of Thought: What AI Reveals About the Human Brain with Tom Griffiths, PhD | E216
The Laws of Thought: What AI Reveals About the Human Brain with Tom Griffiths, PhD | E216 episode artwork
#216
06/02/2026

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Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available for pre-order. Discover how to protect your brain and fu...


Is Psychiatry Looking in the Wrong Place? A Radical Rethink of Brain Health with Dr. Daniel Amen | E215
Is Psychiatry Looking in the Wrong Place? A Radical Rethink of Brain Health with Dr. Daniel Amen | E215 episode artwork
#215
05/12/2026

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Rewiring Connection: How Friendship Shapes the Brain and Heals the Mind with Barnet Bain | E214
Rewiring Connection: How Friendship Shapes the Brain and Heals the Mind with Barnet Bain | E214 episode artwork
#214
04/28/2026

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Dr. Perlmutt...


You’ve Been Pooping All Wrong (And It’s Affecting Your Brain) with Dr. Trischa Pasricha | E213
You’ve Been Pooping All Wrong (And It’s Affecting Your Brain) with Dr. Trischa Pasricha | E213 episode artwork
#213
04/14/2026

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Psychedelic Therapy and Trauma A New Frontier in Mental Health with Dr. Will Van Derveer | E212
Psychedelic Therapy and Trauma A New Frontier in Mental Health with Dr. Will Van Derveer | E212 episode artwork
#212
03/31/2026

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Dr. Perlmutt...


Carbs For Exercise? Let’s Challenge This Idea with Dr. Andrew Koutnik | E211
Carbs For Exercise? Let’s Challenge This Idea with Dr. Andrew Koutnik | E211 episode artwork
#211
03/17/2026

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Why Exercise May Be More Powerful Than Any Alzheimer’s Drug with Dr. Majid Fotuhi | E210
Why Exercise May Be More Powerful Than Any Alzheimer’s Drug with Dr. Majid Fotuhi | E210 episode artwork
03/03/2026

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Toxins Rewrite Your Genes (And Trigger Brain Disease) with Dr. Sarah Marzi | E209
Toxins Rewrite Your Genes (And Trigger Brain Disease) with Dr. Sarah Marzi | E209 episode artwork
#209
02/17/2026

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Optimizing Fertility: What Actually Moves the Needle with Rachel Swanson | E208
Optimizing Fertility: What Actually Moves the Needle with Rachel Swanson | E208 episode artwork
#208
02/03/2026

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Unlocking Immortality? Exploring The Bold New World of Gene Therapy with Elizabeth Parrish | E207
Unlocking Immortality? Exploring The Bold New World of Gene Therapy with Elizabeth Parrish | E207 episode artwork
#207
01/20/2026

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The Power of GLP-1 Agonists: Personalized Medicine for Weight Management - with Ashley Koff, RD | E206
The Power of GLP-1 Agonists: Personalized Medicine for Weight Management - with Ashley Koff, RD | E206 episode artwork
#206
01/06/2026

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Dr. Perlmutter’s groundbreaking new book, Brain Defenders, is now available for pre-order. Discover how t...


PTSD - The Powerfully Therapeutic Role of Hyperbaric Oxygen - with Dr. Mohammed Elamir | E205
PTSD - The Powerfully Therapeutic Role of Hyperbaric Oxygen - with Dr. Mohammed Elamir | E205 episode artwork
#205
07/21/2025

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Today on The Empowering Neurologist podcast we are going to explore PTSD, post traumatic stress disorder, a pervasive issue that can be profoundly debilitating. PTSD is experienced by about 6% of the US population at some point in their lifetime and at any given time approximately 5% of American adults are living with this disorder. Certainly, we see high risk and veterans with PTSD affecting about 11 to 20% of veterans who served in operations Iraqi Freedom and Enduring...


"Parkinson’s is a Man Made Disease, But Reversal is Possible" - with Dr. Ray Dorsey | EP 204
"Parkinson’s is a Man Made Disease, But Reversal is Possible" - with Dr. Ray Dorsey | EP 204 episode artwork
#204
07/07/2025

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In this compelling episode of The Empowering Neurologist, I sit down with Dr. Ray Dorsey, a leading voice in the world of neurology and author of the important new book, The Parkinson’s Plan. Dr. Dorsey is a passionate advocate for changing how we view and address Parkinson’s disease. His message is bold—and urgently needed: Parkinson’s is not simply a disease of aging or bad luck. It is, in his words, “a m...


How a Flickering Light Holds Promise in Alzheimer’s Treatment and Prevention - with Dr. Mai Nguyen | EP 203
How a Flickering Light Holds Promise in Alzheimer’s Treatment and Prevention - with Dr. Mai Nguyen | EP 203 episode artwork
#203
06/23/2025

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I’m thrilled to announce this exciting podcast episode featuring an inspiring and thought-provoking conversation with Dr. Mai Nguyen, CEO and Co-founder of OptoCeutics. Dr. Nguyen is a pioneering force in the field of neurotechnology, and in this episode, we unpack her revolutionary work using non-invasive light stimulation to enhance brain function and potentially prevent neurodegenerative disease.


At the center of our conversation is the EVY, a 40 Hertz light stimulat...


Unseen Toxins: What’s Harming Us in Air, Water, and Everyday Products - with Dr. Aly Cohen | EP202
Unseen Toxins: What’s Harming Us in Air, Water, and Everyday Products - with Dr. Aly Cohen | EP202 episode artwork
#202
06/09/2025

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In our modern world, we are surrounded by a staggering number of invisible threats. These chemicals and pollutants can silently undermine our immune systems, increase our risk for chronic illness, and sabotage our health at the cellular level. That’s why I’m especially excited to welcome Dr. Aly Cohen to this episode of The Empowering Neurologist. This conversation is not only eye-opening, it’s empowering and filled with practical, actionable steps that each of us can tak...


Science of Ketosis: Regain Your Metabolic Health & Age Backwards - with Dr. Dominic D’Agostino | EP 201
Science of Ketosis: Regain Your Metabolic Health & Age Backwards - with Dr. Dominic D’Agostino | EP 201 episode artwork
#201
05/19/2025

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The ketogenic diet has become a household term, often associated with rapid weight loss and an effective means of shedding stubborn fat. However, as my guest on this episode of The Empowering Neurologist, Dr. Dominic D’Agostino, will explain, there is so much more to the ketogenic lifestyle than simply dropping a few pounds. We’re diving deep into the science of metabolism, insulin sensitivity, and how our lifestyle choices impact long-term health, particularly bra...


The Fasting Mimicking Diet - A Powerful Tool for Treating Cancer - with Valter Longo | EP 200
The Fasting Mimicking Diet - A Powerful Tool for Treating Cancer - with Valter Longo | EP 200 episode artwork
#200
05/05/2025

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www.drperlmutter.com. ✉️🌱
Cancer remains a formidable global challenge, with nearly one in six deaths worldwide attributed to the disease. Over 60% of patients undergoing conventional treatments experience severe side effects, highlighting the need for complementary therapies that enhance efficacy and reduce harm.


Dr. Valter Longo, a leading figure in aging and nutritional science, has introduced a groundbreaking approach known as the fasting mimicking diet (FMD). Through years of research, Dr. Longo has shown that cycles of controlle...


The Gut-Brain Paradox: Secrets To Restoring Health - with Steven Gundry | EP 199
The Gut-Brain Paradox: Secrets To Restoring Health - with Steven Gundry | EP 199 episode artwork
#199
04/21/2025

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Welcome back to The Empowering Neurologist! In this episode we have a truly fascinating conversation lined up with none other than Dr. Steven Gundry, a world-renowned heart surgeon-turned-functional medicine expert, whose work has transformed the way we understand diet, disease, and longevity.

Dr. Gundry is no stranger to challenging conventional medical wisdom. In his latest book, The Gut-Brain Paradox: Improve Your Mood, Clear Brain Fog, and Reverse Disease by Healing Your Microbiome (HarperCollins; April 15, 2025), he flips the...


The Science of Longevity: Separating Myths from Breakthroughs - with Dr. Darshan Shah | EP 198
The Science of Longevity: Separating Myths from Breakthroughs - with Dr. Darshan Shah | EP 198 episode artwork
#198
04/07/2025

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We hear so much these days about various “biohacking” techniques that are purported to be helpful for us in terms of improving our health and even extending our lifespan. But I think it's really important that we unpack some of these ideas and get a good understanding as to what they involve and what we can expect if we were to engage them. We're going to explore a variety of hot topics like exosome therapy...


How to Make Your Brain Ageless: Prevent Cognitive Decline & Supercharge Your Mind - with Dale Bredesen | EP 197
How to Make Your Brain Ageless: Prevent Cognitive Decline & Supercharge Your Mind - with Dale Bredesen | EP 197 episode artwork
#194
03/24/2025

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The idea that we can live however we want and then rely on a magic treatment for cognitive issues is unrealistic and dangerous. The reality is that our daily choices profoundly impact our brain’s future, and once cognitive decline begins, there is no clear-cut pharmaceutical solution.


I had the pleasure of speaking with Dr. Dale Bredesen, whose book The Ageless Brain is an incredible resource for protecting brain h...


The Stress Paradox: How to Harness Pressure for a Stronger, Healthier Life - with Sharon Bergquist | EP 196
The Stress Paradox: How to Harness Pressure for a Stronger, Healthier Life - with Sharon Bergquist | EP 196 episode artwork
#196
03/10/2025

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Yes, we need stress in our lives! Staying in our comfort zone may be doing us more harm than good. That’s probably surprising to hear from me having spoken about the importance of reducing stress over the years. But, nonetheless, a level of stress that is not overly damaging, and that may actually have positive benefits. 


Today we are going to learn much more about that will be looking at th...


Yes, Stress Can Be Good: The Health Benefits of Doing Hard Things - with Jeff Krasno | EP 195
Yes, Stress Can Be Good: The Health Benefits of Doing Hard Things - with Jeff Krasno | EP 195 episode artwork
#195
02/24/2025

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We all want to live a stress-free life. But as it turns out, this may not necessarily be in our best interest having a low level of stress of various types turns out to be good for our physiology and can even help us recover from illness. When stress is implemented in this way, it is termed, other words, the upside of low-grade stress. That stress can be exercise, immersion ourselves in cold or hot temperatures, time restric...


Is Lifting Weights the Best Dementia Prevention? Muscle’s Impact on Brain Health - with Dr. Austin Perlmutter | EP 194
Is Lifting Weights the Best Dementia Prevention? Muscle’s Impact on Brain Health - with Dr. Austin Perlmutter | EP 194 episode artwork
#194
02/10/2025

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We all know that exercise is good for the body and specifically, very good for the brain. In fact, exercise is the most important inroad to better brain health, better brain function, protecting the brain against decline, and even with respect to mood issues like depression.


But it's reasonable to ask how in fact does this work? How is it that exercising muscles does good things for the brain?


Treating Alzheimer’s with Light and Sound - with Christian Howell | EP 193
Treating Alzheimer’s with Light and Sound - with Christian Howell | EP 193 episode artwork
01/20/2025

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱Over the last several decades, it’s been interesting to watch the progression of ideas for treating Alzheimer’s change from focusing on brain chemistry to targeting the accumulation of proteins in the brain associated with the disease. Recently, there’s been exciting interest in studying how the brain’s electrical circuits and rhythms change in Alzheimer’s and other brain degenerative disorders.The human brain operates in rhythms, with gamma frequencies playing a critical role in cognitive functions such as memo...


Revolutionizing Mental Health: The Rise of Metabolic Psychiatry - with Dr. Georgia Ede | EP192
Revolutionizing Mental Health: The Rise of Metabolic Psychiatry - with Dr. Georgia Ede | EP192 episode artwork
#192
01/06/2025

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After decades of stagnation, the field of psychiatry is undergoing a transformative shift.

For 75 years, mental health issues were largely viewed as “chemical imbalances” best treated with medications. While these medications have helped many, their efficacy is often limited, and they come with common side effects like fatigue, weight gain, and sexual dysfunction.

Enter metabolic psychiatry—a groundbreaking new approach that reimagines mental health challenges as issues rooted in brain metabolism...


Cancer Survivor: Resilience, Hope, & the Power of Integrative Medicine to Heal - with Dr. Jill Carnahan | E191
Cancer Survivor: Resilience, Hope, & the Power of Integrative Medicine to Heal - with Dr. Jill Carnahan | E191 episode artwork
#191
12/23/2024

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Tune in to The Empowering Neurologist Podcast for an Inspiring Conversation with Dr. Jill Carnahan, Author of Unexpected


I’ve just finished recording a very moving interview with Dr. Jill Carnahan—Functional Medicine expert, speaker, and author. This was an unforgettable conversation about her new book, Unexpected. Dr. Carnahan’s story is one of resilience, empathy, and transformation, and her insights have changed countless lives through her compassionate approach to health...


Hyperbaric Medicine Revolution: Long COVID Relief & PTSD Discoveries - with Dr. Amir Hadanny | EP 190
Hyperbaric Medicine Revolution: Long COVID Relief & PTSD Discoveries - with Dr. Amir Hadanny | EP 190 episode artwork
#190
12/09/2024

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What makes a good brain go bad? And if we can answer that question, how do we fix it? Of all the things that we consider that are important for brain cell function, the activity of the mitochondria is primary. And, what do mitochondria need to function at their best? The answer is not a supplement. It's not other forms of nutrients, it is oxygen. And as it turns out, enhancing, the oxygen availability...


The Seed Oil Scandal: Exposing the Hidden Dangers in Your Diet - with Cate Shanahan, MD | EP 189
The Seed Oil Scandal: Exposing the Hidden Dangers in Your Diet - with Cate Shanahan, MD | EP 189 episode artwork
#189
11/25/2024

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We are certainly all aware of the health consequences associated with consumption of ultra processed foods. And this discussion always moves to the role of the sugars and refined carbohydrates in these foods in terms of threatening our metabolic health - and rightfully so.

But there’s another threat associated with these and other foods that is equally important. And that’s the type of oils they contain. In this episode of The Empowerin...


How Scents Can Improve Memory, Autism and Depression - with Dr. Michael Leon | EP 188
How Scents Can Improve Memory, Autism and Depression - with Dr. Michael Leon | EP 188 episode artwork
#188
09/09/2024

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What can we do to improve our brains? This is clearly a topic that is central to our messaging. And we have focused on a variety of levers to pull, including exercise, sleep, dietary changes, nature, connection, etc. But we've now learned about a powerful input that has proven incredibly effective in improving brain function, especially in a variety pathological situations like cognitive decline, anorexia, depression, and even autism. This innovative a...