Defiant Health Radio with Dr. William Davis

40 Episodes
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By: William Davis, MD

William Davis, MD, cardiologist and author of the #1 New York Times bestselling Wheat Belly books, as well as Undoctored and, most recently, Super Gut, brings the unvarnished truth about many health conditions. So much information in health is crafted by industry, bent to the benefit of healthcare systems, delivered by willfully ignorant physicians. Yet a critical mass of truly useful, safe, effective health information has been reached--but someone has to deliver it to you. That is Dr. Davis' intention. Among the topics the Defiant Health Podcast covers are:--Microbiome health--The key to so many health conditions, as well as preservation...

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Is autointoxication a real thing?
Yesterday at 10:00 PM

Over the years, several dozen cases of "autointoxication," also called "auto brewery syndrome," i.e., people who are intoxicated but deny indulging in any alcoholic beverages, have been documented. Formal testing of these people more recently has indeed revealed disruption of the gastrointestinal microbiome with overgrowth of alcohol-producing bacterial and fungal species. The situation is also remedied by addressing the bacterial and fungal overgrowth, confirming a cause-effect relationship. 

Something to consider, however: If it's possible to become intoxicated from a disrupted GI microbiome, could lesser degrees of alcohol that cause, for example, impaired judgement, reduced impulse control, i...


If you tell me what your small LDL particle number is, I can tell you a ton about your health
10/18/2026

Just knowing what your small LDL particle number is from NMR lipoprotein panel provides huge insight into your physiology, metabolic health, as well as risk for heart disease, certainly far superior to this outdated and nearly useless measure called LDL cholesterol. 

Support the show

YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com


Books:

Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight


Why Can't We Drink Dirty Water (like hunter-gatherers do)?
10/12/2026

Hunter-gatherer human populations are able to drink from puddles and other water sources that we would regard as tainted, yet do not usually get ill. Why is this? Is there something unique in their gastrointestinal microbiomes that make them impervious or more resilient than we are?

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com


Books:

Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and...


How Your Microbiome Controls Love and Hate
10/05/2026

This video is abouIt is becoming clear that the gastrointestinal microbiome is a major factor in human mood and behavior. It can program you for hatred, violence, aggression, and unmask unhealthy behaviors. It can also program you for love, empathy, and generosity. 

Because I know of no psychologist, psychiatrist, or other health professional who can help you manage this critical area of health, I discuss why this is important and point you in the direction of taking control over it. t My Movie

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YouTube channel: https://www.youtube.com/@WilliamDavisMD


NMR Lipoprotein Interpretation Made Simple
09/30/2026

Many people, including most doctors, are overwhelmed when they first receive the results of a NMR lipoprotein analysis. 

Here is a simple way to understand and then apply everything you need to know by addressing a SINGLE VALUE on the panel. 

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com


Books:

Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight

...


Let's clear up 4 common misconceptions about coronary calcium scores
09/18/2026


My 35 years of involvement with CT heart scans that generate coronary calcium scores has provided many important lessons on how to put this measure to use. Unfortunately, many misconceptions surround this technology due to incomplete understanding. 

I therefore provide the rationale and evidence on how to make the most with this important measure. 

Fit, Healthy & Happy Podcast
Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...

Listen on: Apple Podcasts   Spotify

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

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Why Are Small Dense LDL Particles Different?
09/11/2026

The world has been brainwashed by this absurd notion that cholesterol causes heart disease, thereby wasting your time with talk of statin drugs and saturated fat. 

The tragedy is that the REAL causes of heart disease are identifiable and readily correctable. Small dense LDL particles are the "tip of the iceberg" for an entire constellation of metabolic abnormalities that are the causes underlying heart attack, sudden cardiac death, and the need for heart procedures. 

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website fo...


Why 15-Grams Net Carbs?
09/02/2026

https://youtu.be/eWbOiyTfeTQ

Support the show

YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com


Books:

Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight

Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed


How to reduce triglycerides to 60 mg/dl or less
09/01/2026

Here are the easy-to-adopt non-pharmaceutical strategies that you can put to work to keep triglycerides at 60 mg/dl or less, a level that helps you achieve superior metabolic health. 

Triglycerides are a biomarker packed with useful information about health and keeping it at this low level stacks the odds in favor of avoiding heart disease, type 2 diabetes, fatty liver, cognitive impairment and other conditions.

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com


The Nasty Little Monster Called Small Dense LDL
08/25/2026

While the world focuses on what I call the "kindergarten version" of heart disease causation, i.e., cholesterol, they ignore the REAL cause: small dense LDL particles and the entire constellation of abnormal metabolic phenomena that accompany it. 

Once you gain a better understanding of how coronary heart disease (heart attack, sudden cardiac death, need for heart procedures) is caused, you are on your way to taking more effective action in stopping it. 

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for tw...


What happens when you keep triglycerides 60 mg/dl or less?
08/15/2026

Of the four values provided on any standard cholesterol panel, the triglyceride value reveals the most about your health. Ironically, it is often the value most commonly ignored or dismissed, or simply treated using the wrong agents. 

Here is what you can expect if you keep triglycerides 60 mg/dl or less. 

Support the show

YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com


Books:

Super Gut: The 4-Week Plan to...


An end to heart disease click bait: How heart disease is REALLY caused and managed
08/06/2026

You've seen the click-bait headlines: "Take this one supplement and dissolve plaque," or "Eat this one food every day to dissolve plaque." None of this true, any more than reducing cholesterol "dissolves plaque."

There is a logical and scientifically validated approach to gain control over coronary atherosclerotic plaque and thereby risk for heart attack and related cardiovascular events. It begins with identifying, then eradicating, small dense LDL particles. Think of small dense LDL particles as the first domino in a long line of dominoes that will fall just by knocking down the first domino. 

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One of the best kept secrets in healthcare: The diameter of your thoracic aorta
08/05/2026

Many people have had an echocardiogram, CT heart scan, or other imaging test of their heart or chest during which an enlarged ascending thoracic aorta was identified--but you are almost NEVER told. Yet an enlarged aorta is a diseased aorta that puts you at risk over time of aneurysm rupture, dissection, both of which are catastrophic, and "mini-strokes" from fragmentation of atheroclerotic plaque. 

Here is how to know whether this applies to you and, if it does, what you can do about it. 

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

...


Smoke inhalation: Cardiovascular risk factor
07/21/2026

The recent Canadian wildfires that have caused a thick blanket of smoke to cover the upper Midwest and Northeast is, as reported by the media, a threat to people with lung conditions. But it also adds to risk for heart disease, rarely or never mentioned and therefore often dismissed. 

But smoke inhalation is indeed a cardiovascular risk factor. Here is some of the most compelling evidence for this phenomenon.

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: I...


Join our upcoming Caribbean Cruise: The New Science Behind Reshaping Your Body
07/15/2026

Considering joining us on our Caribbean cruise scheduled for Feb-March, 2027? Here's a conversation between me and JJ Flizanes on what you can expect. 

We are packing the schedule full of educational presentations and demonstrations that well The New Body Blueprint, encouraging you to think a new way on how to shape your body while obtaining magnificent health. And you will also enjoy a total of 8 days on a beautiful MSC cruise ship with several Caribbean ports of call. 

Fit, Healthy & Happy Podcast
Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle fr...


Thoracic Aortic Dissection: What To Know
07/14/2026

Senator Lindsay Graham recently died unexpectedly from a thoracic aortic dissection, taking the world by surprise. 

Is this something you should be concerned about for your own health? You may actually have already been tested for this, even if the results were not shared with you. Here is a discussion about what an aortic dissection is, why and how it occurs, how to find out if it applies to you, and what you can do to stop it from posing danger.


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Bacteriocins: Key to surviving the age of antibiotics?
07/12/2026

Normally, you should have numerous species of microbes inhabiting your gastrointestinal tract and other body locations that produce bacteriocins, i.e., natural antibiotics that keep unhealthy microbial species from taking over. Unfortunately, modern antibiotics, while necessary at times, have killed off species that were previously protecting you by producing bacteriocins. This allows the emergence of health problems mostly unique to modern people including weight gain, type 2 diabetes, irritable bowel syndrome, fibromyalgia, depression, anxiety and many others. 

Rebuilding a microbiome that includes species that produce bacteriocins is an important factor in reclaiming control over health disrupted by exposure t...


Why is cholesterol testing not dead yet?
07/03/2026

Why are we still using 1950s technology to predict and manage risk for heart disease in the form of cholesterol testing? Superior methods have been available for >30 years. 

Sadly, the key is money. If superior methods to identify and manage risk for heart disease are essentially without cost, how would the healthcare industry make its money? 

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com


Books:

...


Why does curing type 2 diabetes remain a secret?
06/24/2026

I find it shocking that, as easy as type 2 diabetes is to reverse,  backed up by even human clinical trials validating this concept, few doctors inform their diabetic patients of this. 

Oddly, now that GLP-1 agonist (disastrous) drugs are available, the reduction in blood sugar coupled with weight loss has brought the idea of type 2 diabetes remission to the forefront, since it now is profitable to reverse it. 

But you do NOT need any pharmaceutical to reverse type 2 diabetes in the majority. 

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YouTube channel: https://www.youtube.com/@Will...


How can you know when SIBO is gone?
06/19/2026


If you have made efforts to reverse small intestinal bacterial overgrowth, SIBO, how can you know whether you have succeeded?

Here are a number of indicators you can use to decide. After all, reverse SIBO and the endotoxemia that accompanies it provides huge advantages in virtually every aspect of health: emotional, physical, social. 

Support the show

YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com


Books:

Super Gut: T...


"I have a 'cheat' day once per week--Is that okay"
05/20/2026

If you are trying to eradicate one of the REAL causes of risk for heart disease, small dense LDL particles, is a once-per-week "cheat" day allowable? Can you get away with it by exercising more the following day, or being extra strict? 

No. Unfortunately, small dense LDL particles are unforgiving and persist for an unusually long period in the bloodstream, thereby adding to risk for cardiovascular disease. 

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.co...


Understand the "Universe" of Small Dense LDL Particles
05/14/2026

Why does much of the world cling to the outdated notion that cholesterol is the cause of heart disease and that reducing cholesterol is the solution, even after decades of evidence have more than amply demonstrated that this approach is woefully inadequate? Sadly, it's about money. 

But you do not have to be hogtied by financial concerns. You can take a path that actually works. You can start by measuring small dense LDL particles that gives you a mountain, an entire "universe," of insight into risk for coronary disease and what to do about it. 

Su...


Infertility, Miscarriage, Premature delivery: The Crucial Role of Endotoxemia
05/04/2026

The evolving science has become overwhelming: Lipopolysaccharide endotoxemia, i.e., the entry of bacterial breakdown products into the bloodstream, is a major driver of multiple problems in female reproductive health. Unfortunately, this crucial factor is almost never addressed in conventional healthcare settings. 

Thankfully, there are steps YOU can take personally to address this important health issue. 

Support the show

YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com


Books:

Su...


"Why do I have food intolerances?
04/24/2026

Food intolerances are growing and more and more people are unable to eat FODMAPs-containing foods, histamine-containing foods, nightshades, legumes, fructose-containing foods and numerous others, sometimes reduced to consuming only a handful of "safe" foods. 

Why is this happening, something that was virtually unknown only a generation or two ago? Much of it is due to the excessive proliferation of Proteobacteria species in your gut. But it's not just about food intolerances, as these intolerances are just the tip of the iceberg. 

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

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Why Life is Better Without Wheat
04/15/2026

If you are given the kindergarten version of a healthy diet, well, you can expect mediocre results at best, disastrous results at worst. 

Why not graduate to a higher level of dietary understanding? But don't count on obtaining such insights from conventional sources. Here are some cold, hard facts about the consumption of wheat and grains that everyone should be aware of. 

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com


...


Understanding the Microbiome: Endotoxemia and Translocation
04/07/2026

They are somewhat more advanced concepts, but the microbial phenomena of endotoxemia and translocation are proving to be critical processes in initiating or worsening a long list of human health conditions. Because most mainstream doctors have abdicated their responsibility in providing advice to maintaining or regaining health, it is up to YOU to understand these important concepts. 

Here is a basic discussion to help you understand the importance of these fundamental microbiome concepts. 

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for tw...


What is gluten and why you should avoid it
03/29/2026

Despite my Wheat Belly series of books having been read by millions of people in nearly 40 countries, many people still think that a grain-based diet is healthy. Many also confuse this message with being "gluten-free."

Let's think about this issue more clearly so that you understand the power you have in your hands to assume control over health and weight by being smarter and better informed than the misguided masses following dietary guidelines or are victims of an exploitative food industry. 

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Why is grain elimination good for oral health?
03/16/2026

Scientific insights into the oral microbiome are yielding many new lessons for dental health: mouthwashes are actually dangerous, fluoridated drinking water does not prevent cavities, some toothpastes contain harmful additives. 

But the most important factor for dental health is often neglected: the role of eliminating grains. The amylopectin A of grains is a major factor in degrading dental health and the oral microbiome. 

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com

...


Hunger Hacked
03/16/2026

Support the show

YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com


Books:

Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight

Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed


I answer questions posted by listeners/viewers
03/11/2026


Here I address frequently-asked questions or important issues raised by listeners/viewers. 

Fit, Healthy & Happy Podcast
Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...

Listen on: Apple Podcasts   Spotify

Support the show

YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com


Books:

Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight

Wheat Be...


Does dementia start in the mouth?
03/03/2026

A number of studies in which the brain tissue of people who have died of dementia have revealed the presence of microbial species such as Porphyromonas gingivalis, Fusobacterium nucleatum, and Tannerella forsythia--all oral microbes. This is an example of translocation, i.e., the migration of microbes from one body site to another. But does this cause or accelerate dementia? This remains an unsettled issue. 

However, if you have had an oral microbiome test and you have one or more of these species in your mouth, should you eradicate it? Dental hygiene is likely not enough. For this r...


It's Not Yogurt
02/23/2026

We've been fermenting HUMAN-SOURCED microbes to generate very high microbial counts and obtain specific health benefits. The end-result looks and smells sort of like conventional yogurt, but it is NOT yogurt. (I called it "yogurt" for lack of a better term.) It's my way of generating high counts of important microbes that most people have lost due to antibiotics and other factors. You can enjoy this unique "yogurt" with some blueberries, nuts, or your choice of natural sweetener. 

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YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

M...


Why You Should NOT Measure Apoprotein B
02/21/2026

Apoprotein B provides a virtual count of the lipoprotein particles in the bloodstream that cause coronary heart disease. It is often held up as superior to the widely used LDL cholesterol value. Is this true?

It is true, but it does not mean that measuring apoprotein B tells you much about health. Compare this to the enormous amount of insight provided by measuring the REAL cause of heart disease: small LDL particles that gives you an entire universe of insight into your overall health, as well as risk for heart disease. And it is wonderfully and completely...


What's all this about making "yogurt"?
02/12/2026

Why has yogurt making gone viral?

First of all, it's NOT yogurt. It looks and smells like yogurt. By FDA regulations, something called yogurt must be fermented with traditional yogurt-making microbes Lactobacillus bulgaricus and Streptococcus thermophilus. That's NOT what we are doing.

Instead, we are fermenting human microbes, i.e., microbes that are adapted to the human body and provide substantial benefits but have been lost by most people because of their susceptibility to common antibiotics. Using my methods (prolonged fermentation, addition of prebiotic fiber, selecting microbial species to achieve specific effects) we obtain hundreds...


Are microplastics the newest cardiovascular risk factor?
02/05/2026

The evidence is growing that suggest that microplastics, or more specifically smaller nanoplastics, are triggers for atherosclerotic disease with increased risk for heart attack, stroke, and death. 

While your doctor wastes your time and money obsessing about cholesterol and statin drugs that should have been discarded decades ago, you need to address the REAL factors that cause heart disease. Add nanoplastics to that list. Thankfully, you can begin to make an impact on your ingestion of plastic particles but may need to re-examine many long-accepted habits.

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Reduce and track abdominal visceral fat for improved health
01/29/2026

Abdominal visceral fat, i.e., fat within the abdominal cavity that surrounds abdominal organs, is unique and the source of so many common health problems. While people who are overweight with a protuberant abdomen almost always have an excess of abdomen visceral fat, it can also occur with a flat abdomen. 

You can reduce and track the amount of abdominal visceral fat with home bioimpedance devices. Here are some unconventional but effective ways to reduce/minimize this form of fat while also tracking your results. 

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The Crime Called Type 2 Diabetes
01/24/2026

The crime is not having type 2 diabetes. The crime is that conventional forces in healthcare essentially turn a blind eye to all the ways available to NOT be a type 2 diabetic. 

Pharmaceutical executives throw lavish parties to celebrate the huge revenues that derive from diabetes drugs that now include the awful GLP-1 agonists, while almost no one in healthcare shows people how to not be diabetic--THAT's the crime. 

Support the show

YouTube channel: https://www.youtube.com/@WilliamDavisMD

Blog: WilliamDavisMD.com

Membership website for two-way Zoom group meetings: InnerCircle.Dr...


How long to consume SIBO Yogurt?
01/21/2026

SIBO (small intestinal bacterial overgrowth) is now epidemic in the U.S., affecting around 50% of the population. It is responsible for an impressive range of health conditions from obesity, to type 2 diabetes, to irritable bowel syndrome, to fibromyalgia and numerous others. We have been addressing SIBO with a collection of microbes that I call "SIBO Yogurt," a collection of human-sourced microbes that colonize the small intestine and produce natural antibiotics effective in killing the species of SIBO, a strategy that has been exceptionally effective.

But how long should you consume SIBO Yogurt to confidently correct this situation?<...


Why it's crucial to keep triglycerides at 60 mg/dl or less
01/20/2026

There's one truly helpful value on a standard cholesterol panel: triglycerides. Ironically, it's also the value most likely to be ignored or mismanaged because the doctor wastes your time by focusing on the useless total and LDL cholesterol values, having been brainwashed by the flawed science and pharmaceutical marketing. 

Here is WHY triglycerides are so important, HOW you can reduce your value to the very important level of 60 mg/dl or less without resorting to the use of any pharmaceuticals, only natural and dietary strategies. 


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What do I mean by "Super Body"?
01/13/2026

It's not about having the build of a bodybuilder, nor 6-pack abs, or bulging biceps. It's about having optimal metabolic health that stacks the odds in favor of being free of heart disease, risk for cognitive impairment, cancer, loss of independence and other health conditions. We therefore work to reduce or minimize abdominal visceral fat while restoring youthful musculature. 

We do so starting with unique methods to restore a healthy gastrointestinal microbiome, then restore other factors largely absent from the modern health experience, effects you can track using a variety of methods: biomarkers, grip strength, visceral fat m...