The Longevity & Lifestyle Podcast

What if your body starts warning you long before real symptoms appear? In this episode, Claudia sits down with Mila Reeves to unpack what real health ownership looks like - from reading your body’s early signals to understanding NAD+, peptides, supplement quality, diagnostics, hormones, energy, and the dangerous gap between good science and good marketing.

Maila shares her personal path into longevity, why she believes prevention is no longer optional, how NAD+ moved from addiction clinics into the mainstream longevity world, what most people misunderstand about delivery methods, why quality control in supplements matters far more th...

What if your home is quietly accelerating your aging… or actively supporting your longevity?

In this solo episode, Claudia explores one of the most overlooked pillars of health: your environment.

We spend over 90% of our lives indoors - yet most people focus only on nutrition, exercise, and supplements while ignoring the space their body lives in.

Claudia breaks down:

Claudia von Boeselager is a former Goldman Sachs banker turned biohacker, longevity entrepreneur, peak performance coach, and investor who reversed her biological age by 18 years.

In this conversation, she shares the burnout moment that changed everything, what biohacking really means beyond supplements and gadgets, how purpose and alignment affect health and performance, and why women can use their biology as an advantage in leadership, business, and life.

[00:00] Introduction to Claudia’s journey

[03:00] Purpose, alignment, and “following your bliss”

[07:00] What biohacking really means

[15:00] The burnout moment that changed everything

[20...

Ever blanked in a meeting or "frozen" during a big presentation? You aren't alone.

Communication expert Matt Abrahams joins Claudia von Boeselager to explain the science of why high performers blank out and how to rewire your brain to stay calm and clear.

Download my FREE 10 Life & Longevity Hacks Playbook to start living smarter and stronger: https://longevity-and-lifestyle.com/freebie

In this episode, we dive into:

In this personal solo episode, Claudia shares a powerful and unexpected experience - losing her voice completely for three days.

What initially felt frustrating became a profound reminder of how the body communicates when we’re moving too fast.

In this reflective conversation, Claudia explores the deeper meaning behind forced silence and what it taught her about listening, slowing down, and reconnecting with our inner signals.

In this episode we explore:

• What losing her voice revealed about stress and overextension

• Why the body often speaks before burnou...

What if your vision was telling you far more about your health than you realized?

In this fascinating episode, Dr. Meenal Agarwal, board-certified optometrist, spatial awareness expert, and authority on the eye–brain connection, reveals how vision is not just about eyesight - it’s a direct reflection of brain function, nervous system state, and emotional health.

Blending clinical science, neuroscience, mindfulness, and compassion, Dr. Agarwal explains how stress, trauma, and chronic overload subtly alter how we see the world - and how retraining vision can support healing, resilience, and longevity. From spat...

What if desire isn’t indulgence - but your life force?

In this deeply embodied conversation, intimacy and sacred sexuality coach Olga Kaplan returns to explore how trauma lives in the body, why intimacy is about presence, and how conscious kink and BDSM can be used therapeutically for healing.

We explore:

• What intimacy truly means (deep presence with yourself and another)

• Tantra as weaving life experiences into embodied aliveness

• The difference between kink, BDSM and trauma-informed practice

• Why trauma is not the event — but what happened without consent

What if “heart health” isn’t about managing numbers… but fixing what’s driving vascular aging in the first place?

In this episode, triple board-certified cardiologist Dr. Chris Davis joins Claudia (with Lumara co-founders Ashley Madsen and Alexandra Cochrane) to unpack a modern, prevention-first approach to cardiovascular longevity.

We explore:

What if psilocybin wasn’t just a mental health breakthrough — but a longevity intervention?

In this powerful, science-driven conversation, Dr. Louise Hecker shares groundbreaking research exploring how psilocybin’s active metabolite, psilocin, may influence the fundamental biology of aging.

We explore:

• How psilocybin impacts cellular senescence, one of the key drivers of aging

• The surprising effects on oxidative stress and antioxidant pathways

• What happened to telomere length in aging cell models

• Why serotonin (5-HT) receptors exist throughout the body — not jus...

What if aging, fatigue, and chronic disease all shared the same root cause?

In this episode, Dr. Ash Kapoor, physician and expert in precision and longevity medicine, reveals why mitochondrial dysfunction sits at the center of metabolic breakdown, cardiovascular disease, inflammation, and accelerated aging. Rather than focusing on symptoms, Dr. Kapoor explains how cellular energy production determines how well we heal, perform, and age.

We explore why calorie counting misses the mark, how modern lifestyles damage mitochondrial function, and why restoring metabolic flexibility is one of the most powerful...

What if disease wasn’t inevitable — but preventable?

In this thought-provoking episode, visionary entrepreneur and philanthropist Naveen Jain challenges the foundations of modern medicine and makes the case for a bold new approach to longevity. Known for his moonshot mindset, Naveen explains why healthcare is broken, why we wait until we’re sick to act, and how proactive diagnostics and gut health could radically extend healthspan.

Drawing on his work in microbiome research, data-driven diagnostics, and preventive health, Naveen shares why curiosity, accountability, and big thinking are essential if we want to end chronic disease — not just...

Inflammation may feel like a modern problem — but Ayurveda understood it over 5,000 years ago.

In this deeply grounding episode, Dr. Shivani Gupta, Ayurvedic practitioner, researcher, and author of The Inflammation Code, reveals how ancient Ayurvedic wisdom is finally being validated by modern science. From circadian rhythm and gut health to nervous system regulation and women’s hormones, Dr. Shivani explains why so many of us are chronically inflamed — and how simple daily rituals can restore balance, energy, and longevity.

We explore why inflammation, not aging, is driving fatigue, brain fog, hormonal chaos, and perimenopause symptoms, how “m...

What if stress wasn’t your enemy—but your greatest teacher?

In this episode, nervous system and HRV expert Salim Najjar reveals how heart rate variability acts as the language of the nervous system, guiding us toward emotional resilience, clarity, and longevity. Drawing from his own journey—from entrepreneurial burnout to nervous system sovereignty—Salim explains why learning to regulate stress is no longer optional in modern life.

We explore

What if pain isn’t a sign of damage — but a signal for change?

In this powerful conversation, Dr. Kelly Starrett, world-renowned coach, physical therapist, and co-founder of The Ready State, breaks down what actually keeps the human body healthy, mobile, and resilient across a lifetime. From movement and sleep to nervous system safety and social connection, Kelly explains why most people are chasing optimization while ignoring the fundamentals that truly matter.

We explore why sitting is quietly destroying mobility, how the brain interprets pain as threat, why movement signals safety to the nervous system, and...

What if your stress responses, emotional patterns, and even motivation weren’t flaws to fix but signals to understand?

In this powerful episode, Dr. Rewire (Dr. Alok Trivedi) reveals how emotional biohacking and brain DNA insights can transform the way we relate to stress, performance, and ourselves. Drawing on nearly three decades of clinical experience, Dr. Rewire explains why emotions are data, not directives and how rewiring the nervous system can unlock peace of mind, resilience, and longevity.

We explore how personalised brain DNA patterns influence motivation, stress tolerance, recovery, and relationships and why one-size-fits-all bi...

Why does hunger feel so loud — and why does willpower so often fail?

In this illuminating episode, Sarah Kennedy, founder and CEO of Calocurb, unpacks the biology of hunger, the gut-brain axis, and the powerful role of GLP-1 in appetite regulation. Drawing on over 15 years and $30 million of New Zealand government-backed science, Sarah explains why hunger is driven by our most primitive brain systems — and how understanding this biology can finally bring peace with food.

We explore how bitter taste receptors in the gut stimulate appetite-suppressing hormones, why dieting can actually increase hunger over time, and...

What happens when life gives you a second chance?

In this powerful episode, world-record mountaineer, author, and resilience expert Jenn Drummond shares how surviving a near-fatal car crash became the defining line between the life she was living — and the life she chose to claim.

From promising she’d “do something significant” if she lived, to summiting Everest and completing the second-highest peaks on every continent, Jenn reveals why courage isn’t something you’re born with — it’s something you build, one brave step at a time.

We explore:

What if your cravings, emotional eating, and daily food choices weren’t driven by lack of willpower — but by biology, psychology, and an environment designed to hijack your instincts?

In this eye-opening episode, visionary entrepreneur and creator of WildFit, Eric Edmeades, breaks down the evolutionary roots of hunger, the truth about sugar and stress, and why most modern diets fail. Eric reveals how our ancient programming collides with today’s food landscape — and how to reclaim our natural vitality by understanding what the body is truly asking for.

With warmth, clarity, and powerful storytelling, Eric guides u...

What if health optimization wasn’t just for the elite — but something every teacher, firefighter, and family could access?

In this inspiring episode, Jim Donnelly, founder and CEO of Humanaut Health (and former founder of Restore Hyper Wellness), shares how he’s building the most comprehensive, prevention-driven longevity model to date. From advanced diagnostics and regenerative medicine to behavior change and coaching, Jim reveals what it truly takes to add 10–20 healthy, vibrant years to life.

He opens up about the loss of his father, surviving a near-fatal car accident, and how stem cell therapy transformed his reco...

Pain might feel like an inevitable part of aging — but what if it’s actually fixable?

In this episode, Forrest Smith, CEO and co-founder of Kineon, unpacks the cutting-edge science behind red light and laser therapy, why inflammation is the real driver of pain and accelerated aging, and how daily, targeted phototherapy can transform mobility, energy, and long-term health.

We explore the link between inflammation and chronic disease, the surprising gut–brain–thyroid connection, and why repairing internal tissue with the right light wavelengths can dramatically shift your health trajectory.

We cover:

When it comes to longevity, your gut might hold the master key. In this fascinating episode, Colleen Cutcliffe, PhD, CEO and co-founder of Pendulum Therapeutics, reveals how a single gut bacterium—Akkermansia muciniphila—is transforming the future of metabolic and hormonal health.

From her daughter’s early health challenges to pioneering live Akkermansia in supplement form, Colleen shares her journey from biotech to natural therapeutics. Discover how the microbiome impacts metabolism, energy, brain function, menopause, and even GLP-1 hormone production—the same pathway drugs like Ozempic mimic.

We explore:

When it comes to longevity, your gut might hold the master key. In this fascinating episode, Colleen Cutcliffe, PhD, CEO and co-founder of Pendulum Therapeutics, reveals how a single gut bacteriu, Akkermansia muciniphila - is transforming the future of metabolic and hormonal health.

From her daughter’s early health challenges to pioneering live Akkermansia in supplement form, Colleen shares her journey from biotech to natural therapeutics. Discover how the microbiome impacts metabolism, energy, brain function, menopause, and even GLP-1 hormone production—the same pathway drugs like Ozempic mimic.

We explore:

What’s the true return on investment when it comes to your health?

In this special episode, Claudia joins Liz Bradford on the Health ROI Show to share how she reversed her biological age by 17 years, all while running multiple businesses and raising a family. Together, they unpack the data-driven strategies that deliver the biggest health ROI: from optimizing sleep and managing stress to rebalancing hormones and designing sustainable daily systems that work for high performers.

You’ll learn:

What if the secret to longevity wasn’t more movement but the right kind of movement?

In this episode, Peter Simonson, President, Co-Founder, and Board Member of Juvent, reveals how NASA-backed micro-impact technology is transforming bone density, balance, and vitality from the ground up.

We unpack the science of mechanotherapy, how gentle vibrations can stimulate bones and circulation, and why this “passive exercise” could be a game-changer for aging well — especially for those recovering from injury or struggling with mobility.

We explore:

Are Hidden Toxins Silently Aging You From the Inside Out?

Brain fog. Fatigue. Anxiety. Hormonal chaos.

For millions, these symptoms aren’t just “stress” — they’re signs of toxic overload.

In this episode, Dr. Chris Shade, founder of Quicksilver Scientific and one of the world’s leading experts on mercury and detoxification, reveals how environmental toxins, heavy metals, and everyday exposures are quietly disrupting your mitochondria, hormones, and brain — and what you can do to reverse it.

This isn’t another “detox fad.” It’s cutting-edge biochemistry meets practical longevity science — from the man who helped...

Can 8 Minutes Really Transform Your Fitness, Metabolism, and Longevity?

We’ve been told we need hours of cardio each week to stay fit but what if the science says otherwise?

In this episode, Ulrich Dempfl, co-founder and CEO of CAROL Bike, reveals how AI-powered workouts and REHIT (Reduced Exertion High-Intensity Training) are revolutionizing exercise by delivering maximum fitness results in minimum time.

This isn’t another quick-fix fitness fad. It’s a data-driven, scientifically validated method backed by research from top universities — and it’s transforming how busy, high-performing people train, burn fat, and extend...

What if everything you were taught about chronic disease and even aging itself was wrong?

In this eye-opening episode, physician, medical school professor, and author Dr. Robert Lufkin reveals how he reversed his own four chronic diseases by questioning conventional medicine and turning to lifestyle-based health. We explore the biggest “lies” in medicine, why pills and surgeries often fail to cure chronic illness, and the powerful role of metabolic health in preventing conditions like Alzheimer’s, cancer, and diabetes.

Dr. Lufkin also dives into the cutting edge of longevity science—from rapamycin and epig...