The Incubator

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This special edition of The Incubator podcast features a neonatal cardiology journal club discussion hosted by Dr. Nim Goldshtrom and Dr. Adrienne Bischoff. The episode covers several recent studies in neonatal hemodynamics and congenital heart disease, providing insights for clinicians and researchers in the field.

Key topics include:

The impact of early hemodynamic screening on outcomes in extremely preterm infantsUpdated guidelines for targeted neonatal echocardiographyThe relationship between patent ductus arteriosus and bronchopulmonary dysplasia-associated pulmonary hypertensionUse of vasopressin in newborns with refractory acute pulmonary hypertensionResponse to inhaled nitric oxide in...

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Placental Pathology Contributes to Impaired Volumetric Brain Development in Neonates With Congenital Heart Disease.

Nijman M, van der Meeren LE, Nikkels PGJ, Stegeman R, Breur JMPJ, Jansen NJG, Ter Heide H, Steenhuis TJ, de Heus R, Bekker MN, Claessens NHP, Benders MJNL; CHD LifeSpan Study Group ‡.

J Am Heart Assoc. 2024 Mar 5;13(5):e033189. doi: 10.1161/JAHA.123.033189. Epub 2024 Feb 29.

PMID: 38420785 Free PMC article.

As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the sh...

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Impact of early screening echocardiography and targeted PDA treatment on neonatal outcomes in "22-23" week and "24-26" infants.

Giesinger RE, Hobson AA, Bischoff AR, Klein JM, McNamara PJ.

Semin Perinatol. 2023 Mar;47(2):151721. doi: 10.1016/j.semperi.2023.151721. Epub 2023 Mar 5.

PMID: 36882362

As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode...

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Vasopressin in newborns with refractory acute pulmonary hypertension.

Ouellet S, Drolet C, Morissette G, Pellerin A, Hébert A.Pediatr Res. 2024 May;95(6):1572-1577. doi: 10.1038/s41390-023-02995-3. Epub 2024 Jan 11.PMID: 38212386

As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

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Perioperative Brain Injury in Relation to Early Neurodevelopment Among Children with Severe Congenital Heart Disease: Results from a European Collaboration.

Neukomm A, Claessens NHP, Bonthrone AF, Stegeman R, Feldmann M, Nijman M, Jansen NJG, Nijman J, Groenendaal F, de Vries LS, Benders MJNL, Breur JMPJ, Haas F, Bekker MN, Logeswaran T, Reich B, Kottke R, Dave H, Simpson J, Pushparajah K, Kelly CJ, Arulkumaran S, Rutherford MA, Counsell SJ, Chew A, Knirsch W, Sprong MCA, van Schooneveld MM, Hagmann C, Latal B; European Association Brain in Congenital Heart Disease (EU-ABC...

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Response categorization and outcomes in extremely premature infants born at 22-26 weeks gestation that received inhaled nitric oxide for hypoxic respiratory failure.

Boly TJ, Dagle JM, Klein JM, Rios DR, McNamara PJ, Giesinger RE.

J Perinatol. 2023 Mar;43(3):324-331. doi: 10.1038/s41372-022-01582-4. Epub 2022 Dec 12.

PMID: 36509816 Free PMC article.

As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna...

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Patent Ductus Arteriosus and Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension: A Bayesian Meta-Analysis.

Villamor E, van Westering-Kroon E, Gonzalez-Luis GE, Bartoš F, Abman SH, Huizing MJ.

JAMA Netw Open. 2023 Nov 1;6(11):e2345299. doi: 10.1001/jamanetworkopen.2023.45299.

PMID: 38015504 Free PMC article.

As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode a...

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Cardiopulmonary physiological effects of diuretic therapy in preterm infants with chronic pulmonary hypertension.

Zhu F, Ibarra Rios D, Joye S, Baczynski M, Rios D, Giesinger RE, McNamara PJ, Jain A.

J Perinatol. 2023 Oct;43(10):1288-1294. doi: 10.1038/s41372-023-01742-0. Epub 2023 Aug 7.

PMID: 37550529

As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The...

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In this episode of the Incubator: At the Bench, we talk with Dr. Erin Plosa who is a neonatologist and physician scientist at Vanderbilt University Medical Center. We learn what inspired Dr. Plosa to pursue neonatology and learn about her background and career as a lung biologist. Dr. Plosa talks about the importance of collaboration in scientific research and highlights her work studying the role of integrins and the extracellular matrix during lung development. She discusses the role of the extracellular matrix in alveologenesis, fusion of the alveolar capillary barrier, and in...

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In this engaging episode of The Incubator podcast, Dr. Terrie Inder, a pioneer in neonatal neurology, shares her journey and insights into newborn brain development. Dr. Inder discusses the complexities of neonatal brain injury, emphasizing that it's not just about visible hemorrhages, but also about the brain's overall maturation process. She highlights the importance of understanding "brain dysmanturation" and how the NICU environment significantly impacts neurodevelopment.

Dr. Inder challenges the neonatal community to rethink their approach to brain care, advocating for more family involvement, enriched environments, and tailored interventions for...