Heart Doc VIP with Dr. Joel Kahn

This week, Dr. Kahn presents the case of a patient seen this month at the Kahn Center for Cardiac Longevity who, over the course of five years, has reversed artery aging and plaque and is enjoying excellent health. He discusses the program used to achieve these benefits. This case, along with many others from the Kahn Center, offers hope for maintaining youthful arteries throughout your life.

Other topics include the failure of NR in Parkinson's disease, lipoprotein(a) variability and its relationship to carotid plaque, vegan diets for type 2 diabetes, the USDA dietary guidelines and health, caffeine...

This week, Dr. Kahn presents a new scientific statement by the American College of Cardiology on nutrition to prevent heart disease. The emphasis is on plant-based choices while limiting red meat, processed foods, and excess added sugar. Sometimes, hearing the same recommendation over and over can help.

Other topics include statin protection during chemotherapy, retatrutide for weight loss, the MIND diet for brain health, walnuts to boost mood, chronic inflammation and heart disease as measured by CRP and GlycA, and pomegranates for heart health.

Thanks to our sponsor, XtendLife. Use the discount code KAHN15 at...

This week, as a bonus, Dr. Kahn interviews a Detroit clothing legend, Phil, who celebrated his 100th birthday recently by buying a new sports car! He is approaching his 78th wedding anniversary with his beautiful wife. He discussed his early days in business and early successes, and his health journey, relying a lot on the education he got by repeatedly visiting the Pritikin Longevity Center.

This is an uplifting session with a very bright man with a lot of wisdom.

This week, Dr. Kahn brings back the topic of Mankai Duckweed, the smallest edible plant, which provides a complete protein profile, >200 polyphenols, B12, choline, folate, Omega-3s, and other nutrients. Mankai was previously available as a frozen cube but has returned to the market as a user-friendly powder. Mankai is available here: partners.eatmankai.com/AA-DRKAHN

Other topics include a trial of ablation in atrial fibrillation, early cancer screening blood tests (Galleri), a new cholesterol medication, obicetrapib, soy intake and lower breast cancer risk, and the power of a calcium CT score of zero.

Thanks...

In this episode, Dr. Kahn interviews Ben Tammetta, founder of H2Biohacker, about inhaled molecular hydrogen.

They discuss the research behind it and its potential role in supporting health at the cellular level. Dr. Kahn has used molecular hydrogen daily for nearly a year and shares how he feels it has supported his health.

Use discount code DrKahn200 at H2Biohacker, or visit this link.

This week, Dr. Kahn discusses a large study on the impact of whole-grain consumption on heart health. The review article also addresses the optimal number of daily servings for improving weight, blood pressure, blood sugar, and cholesterol. Dr. Kahn offers ideas for incorporating more whole grains into your daily diet.

Other topics include movement span, medications that may lower dementia risk, hot liquids and cancer, weekend warrior activity, ProLon and heart function (www.prolonlife.com/drkahn), the role of CGMs, and, finally, a paper on cockroaches! 

Please visit xtendlife.com for GG Pure and use d...

This week, Dr. Kahn discusses two large new studies examining the role of routine coronary artery calcium CT scoring around age 61 and its impact on clinical outcomes. Dr. Kahn favors getting a first calcium CT score at age 45 or younger.

One study found that potentially unnecessary statin use was three times higher when a calcium CT score was not available. Patients were also much more likely to follow their recommended treatment when calcium scoring results were available. The second study found that CT results led to a major change in therapy for one in five people. These...

This week, Dr. Kahn discusses the widespread disappointment following Novartis' announcement that its 8,000-patient HORIZON trial of a lipoprotein(a)-lowering drug failed to meet its primary endpoint. The news came as a major surprise and disappointment to patients eagerly awaiting access to this medication. No additional details have been released, and there is not yet a published paper to review. Dr. Kahn discusses the possible reasons the trial failed and what he plans to do moving forward.

Other topics include lifestyle factors associated with sudden cardiac arrest, mindfulness for elevated blood pressure, hormone therapy and the...

Dr. Kahn interviews Anurag Singh, MD, PhD, Chief Medical Officer of Timeline Nutrition, whose research has focused on urolithin A, a compound produced from nutrients found in pomegranates.

Nearly 20 years of research have resulted in more than 500 studies, 25 human clinical trials, and 80 patents related to this unique compound, which is available in powders, capsules, and even gummies. Research suggests that urolithin A may safely support mitochondrial renewal and muscle strength. Timeline Nutrition was also selected as a finalist in the $101 million XPRIZE Healthspan competition.

Listeners can use the discount code KAHN10 to save on orders...

This week, Dr. Kahn reviews several important studies presented at the European Society of Cardiology Congress. The REACT trial examined how often previously undetected atherosclerosis appears in the coronary, carotid, and femoral arteries. The results are startling and reinforce the importance of the #TestNotGuess approach to cardiovascular health.

Dr. Kahn also discusses encouraging research showing how plant-based diets may reduce cardiovascular disease risk. 

Additional topics include:

This week, Dr. Kahn returns to one of his passion topics: educating young people about healthy lifestyles beginning in middle school and high school, if not earlier, and setting them up for a healthy future. A new study finds that the risk of heart disease and actual changes in the arteries are both common by age 23. It's a tragic reality.

Other topics include dry cleaning and Parkinson's disease, amino acids and prostate cancer risk, meal timing and longevity, cooking classes and healthy diets (PlantRN), statins at age 80, exercise and the reversal of artery disease, lipoprotein(a) and...

This week, Dr. Kahn discusses the triglyceride-to-HDL (TG/HDL) ratio and how this simple lab measurement can help predict insulin resistance, type 2 diabetes, liver disease, and heart disease. It is also a marker of visceral fat and an easy, readily available way to add valuable risk information to your health journey. Dr. Kahn also discusses how genetics can influence the TG/HDL ratio.

Other topics include tomatoes for the liver, tirzepatide for the heart, lifestyle for the heart, junk food and prostate cancer, belly fat and the heart, alcohol and the heart, and the power of climbing...

This week, Dr. Kahn discusses new research showing that after just 4 weeks of eating a whole-food, plant-based diet, sophisticated measures of gene activity demonstrate a reversal in aging and a reduction in inflammation. In another study, the calorie advantage of a plant-based diet is discussed, with the equation H=N/C (Health = Nutrition/Calories) proving to be a useful reminder. Finally, athletic performance in college athletes eating plant-based or omnivore diets was equivalent, which is reassuring to many. Dr. Kahn and his wife will begin their 50th year of plant-based diets in September.

Other topics include more...

This week, Dr. Kahn discussed new research on advanced glycation end-products (AGEs) and cooking methods. High levels of AGEs promote many disease states and can be avoided with water-based cooking methods like steaming, boiling, and pressure cooking.

Other topics include visceral fat loss and brain health, bitter hops extract for weight loss, the Planetary Health Diet, fructose in the diet and cancer growth, a failed study on inflammation, and the role of multivitamins in cardiac health. 

Thanks to the Fresh Pressed Olive Oil Club and the $1 offer at getfreshDrKahn.com.

This week, Dr. Kahn discusses new data from the amazing Valter Longo, PhD, and his colleagues regarding optimizing diet for both longevity and strong muscles. In a new publication, Dr. Longo used mouse models to show that animals fed a Longevity Diet, as described in his book, lived longer. However, when moderate amounts of methionine, an amino acid, were included in the diet, frailty was avoided.

He then analyzed a dataset of 200,000 health professionals in the United States and found that those consuming the highest amounts of animal protein had double the risk of type 2 diabetes, as...

In this bonus episode, Dr. Kahn interviews functional medicine specialist Ivan Rusilko about the importance of advanced lab panels. Together, they explore the full spectrum of cardiac lab testing, with a special focus on inflammation, insulin resistance, and how these markers can uncover hidden cardiovascular risk.

If you are a health care practitioner, set up an account at accessmedlab.com. Mention the Heart Doc VIP Podcast when creating your new practitioner account to receive 50% off CardioPro™ Advanced Diagnostic Panels, providing unparalleled insights into patient health.

This week, Dr. Kahn discusses the FDA approval of the first oral PCSK9 inhibitor, Lipfendra (enclicitide), taken as a 20 mg daily tablet. In a study of nearly 3,000 patients with elevated LDL cholesterol despite treatment with statins and, in many cases, ezetimibe, LDL-C dropped by more than 50% while Lipoprotein(a) levels fell by 28%, with an excellent safety profile. The medication is expected to retail for approximately $315 per month and will be available in pharmacies soon. A larger outcomes trial evaluating its impact on heart attack and stroke rates is currently underway.

Other topics include oatmeal for diabetes, avocados...

This week, Dr. Joel Kahn explores important new research showing how elevated inflammation, measured by Interleukin-6 (IL-6), may dramatically increase cardiovascular risk in people with high Lipoprotein(a), or Lp(a). He explains why IL-6 is emerging as an important biomarker and reviews the other inflammation tests he routinely uses at the Kahn Center, including hs-CRP, MPO, Lp-PLA2, NT-proBNP, fibrinogen, ferritin, the sedimentation rate, and the white blood cell count.

Dr. Kahn also discusses Lilly's newly approved oral weight loss medication, the ABCDEF framework for cardiovascular prevention, the growing evidence linking erectile dysfunction and sleep apnea to...

Dr. Joel Kahn explores the latest science on supplements that may help slow or reverse atherosclerosis, building on a recent discussion from Simon Hill's The Proof podcast. He takes a closer look at the evidence behind vitamin K2, niacin, pycnogenol with centella asiatica, beta-cyclodextrin, and bergamot, explaining where the research is strongest and what it could mean for heart health.

Additional topics include new research on nutrient deficiencies to watch for in vegan diets, the potential kidney risks of certain calcium channel blockers, the health benefits of onions, advanced plaque measurements from coronary CT angiography, the connection...

This week, Dr. Kahn reviews important new research showing that the commonly prescribed antidepressant Prozac (fluoxetine) may disrupt cholesterol metabolism, injure the endothelium (the delicate lining of arteries), and potentially increase cardiovascular risk. He also examines growing evidence linking proton pump inhibitors (PPIs) and several common cancer therapies to endothelial damage, emphasizing that patients should always discuss the risks and benefits of these medications with their healthcare team rather than stopping treatment on their own.

Other topics include new Harvard research showing that combining aerobic exercise, strength training, and less time spent watching television can reduce the...

Can a simple gratitude practice improve your heart health?

This week, Dr. Kahn explores the growing science linking gratitude to better well-being, improved sleep, lower inflammation, and even enhanced cardiac function. He shares his own gratitude practices and offers practical ways to incorporate them into daily life. 

Also covered in this episode: how adherence to Life's Essential 8 is associated with longevity, even among the ultra-elderly; the importance of identifying cholesterol hyperabsorbers; the connection between obesity and cancer risk; the relationship between sleep apnea and Lipoprotein(a); why strength training is especially important for women; and t...

In this special 500th episode of Heart Doc VIP, Dr. Joel Kahn reflects on the personal and professional journey that shaped his 36-year career in cardiology and preventive medicine. From his childhood in Detroit and medical training at the University of Michigan to founding the Kahn Center for Cardiac Longevity, Dr. Kahn shares the mentors, experiences, and lessons that influenced his approach to patient care.

He also reviews new research on heart disease mortality in the United States, vitamin K2 and coronary artery calcium progression, plant-based diets for chronic kidney disease, factors influencing carotid intima-media thickness (CIMT...

In Episode 499, Dr. Joel Kahn explores the growing importance of apolipoprotein B (ApoB) testing as a powerful tool for assessing cardiovascular risk. He reviews new research highlighting why ApoB may provide a more complete picture of atherosclerosis risk than traditional cholesterol measurements alone and explains how it relates to LDL-C and Lp(a).

Dr. Kahn also discusses several noteworthy studies in preventive medicine and longevity, including research linking GLP-1 medications to lower cancer risk, the potential DNA-protective effects of melatonin, and new findings on stroke and clot prevention in patients with atrial fibrillation. Additional topics include the...

Dr. Joel Kahn dives into a groundbreaking Phase 1 trial of Verve 102, a one-time intravenous gene-editing treatment that silences the PCSK9 gene to produce lasting LDL cholesterol reduction. Among 35 participants, the high-dose group saw LDL drop by 62% with mostly mild side effects — promising results, though Phase 2 and 3 trials and 15 years of follow-up still lie ahead.

Also covered: updated colorectal cancer screening guidelines now starting at age 45, healthy lifestyle habits cutting mortality risk in cancer survivors by one-third, real-world weight regain data after stopping GLP-1 medications, why your B12 "normal" range may be too low, a blood test that ma...

In this episode of HeartDoc VIP, Dr. Joel Kahn breaks down the newly released — but not yet fully published — results from the highly anticipated Triumph-1 study on retatrutide, an investigational weight loss medication that's already generating major buzz in the cardiometabolic world.

The reported weight loss results at 80 and 104 weeks are remarkable, with side effects appearing consistent with other medications in this class, including semaglutide and tirzepatide. Dr. Kahn discusses what's known so far, what questions still remain, and why the full peer-reviewed publication is so important before drawing final conclusions on risks and benefits. FDA approval may...

This week, Dr. Kahn discusses Bryan Johnson's efforts to reverse his "biological age" and the 41 lessons he has shared along the way. These are valuable insights that Dr. Kahn largely endorses.

Other topics include the sit-to-stand test; how PCOS can become PMOS; therapies for Peyronie's disease and PSA testing; plant-based diets and aging; plant-based diets during pregnancy; pregnancy complications; and the cardiac health of offspring. 

A big thanks to Igennus for supporting the podcast. Use discount code DrKahn to save on the BeKind line of plant-based nutritional products.

This week, Joel Kahn, MD, dives into fascinating new research on aged garlic extract and its potential role in healthy aging, muscle function, and cardiovascular wellness. He reviews a recent study showing how aged garlic extract improved muscle and aging markers in mice while also activating the NAMPT pathway in humans, which may help boost NAD+ production.

Dr. Kahn also breaks down several newer studies highlighting the cardiovascular benefits of aged garlic extract, a supplement he's used at the Kahn Center for more than a decade. He discusses the specific Kyolic formula available here: Kyolic Aged Garlic...

This week, Dr. Kahn discusses his long-standing interest in the amino acid glycine and its potential health benefits. Sleep is a key focus, highlighted by a new report on the widespread difficulty adults face in getting a full night's rest. Glycine may also offer favorable cardiovascular support.

Additional topics include coffee and aging, methamphetamines and heart attacks, Lipoprotein(a) and cardiovascular risk, yoga and overall health, a tribute to Eugene Braunwald, MD, TMAO and atherosclerosis, and a new study on the benefits of adopting heart-healthy habits early in life. 

Thanks to the Fresh Pressed Olive O...

This week, Dr. Kahn reviews new data from the Global Burden of Disease study analyzing the relationship between diet and death from heart disease. In 2023, an estimated 5.9 million deaths worldwide were linked to poor dietary choices, led by excessive sodium intake and insufficient consumption of fruit and whole grains. It's a fascinating and important study with clear takeaways.

Other topics include stents for angina, causes of sudden cardiac death, daytime napping and health outcomes, plastic-free diets, PCSK9 inhibitors vs. statins, calcium supplements, and the purity of fish oil samples.

Thanks to the Fresh Pressed Olive...

This week, Dr. Kahn addresses a topic gaining attention in the media: whether taking the shingles vaccine (Shingrix in the USA) may reduce the risk of heart events and dementia. Multiple studies suggest this could be true, although no randomized trials have been performed to confirm it. Furthermore, most of these studies focus on a version of the vaccine that was discontinued in the U.S. in 2020 (Zostavax), making the assumption that Shingrix provides the same benefits somewhat speculative. This is a topic worth discussing with your primary care team.

Other topics include controversies in nutrition, B...

This week, Dr. Kahn dives into heart disease in "masters athletes," highly active individuals over 35 who train and compete at a serious level. Despite their fitness, research shows they may face equal—or even higher—rates of cardiovascular issues like arrhythmias, coronary artery disease, and aortic dilation. A new consensus statement breaks down what to watch for and recommends advanced screening like EKGs, coronary calcium scans, and detailed blood work.

Beyond that, Dr. Kahn shares insights from his own recent mitral valve surgery recovery and explores why common heart risk calculators often miss people who go on to h...

This week, Dr. Kahn shares an update on his recovery following robotic mitral valve repair surgery at the Cleveland Clinic. Just 10–12 days post-op, he walks through his experience—from diagnosis and testing to surgery with Marc Gillinov, MD. 

He covers the procedure, time in the ICU, and early recovery milestones, along with what's next in his healing journey.

Thanks to Igennus for sponsoring this episode—visit igennus.com and use code DrKahn.

This week, Dr. Kahn shares exciting updates from the American College of Cardiology meeting, highlighting several new trials focused on reducing heart events in patients with diabetes and those with established heart disease. The results are promising and could help prevent strokes, heart attacks, and even save lives.

Additional topics include vegan diets and cancer risk, heart disease in police officers, the link between Alzheimer's disease and statins, concerns around erythritol sweeteners, Lp(a) levels in stent patients, niacin for fatty liver disease, and the role of beta blockers after heart attacks. 

This episode is b...

What if a quick, painless ultrasound could reveal your true vascular age?

In this bonus episode of Heart Doc VIP, host Dr. Joel Kahn sits down with Joseph Ence to discuss CIMT (carotid intima-media thickness)—a simple, non-invasive test used in over 5,000 research studies over the past 20+ years to measure plaque and thickness in the carotid arteries.

Safe and radiation-free, this ultrasound provides valuable insight into your cardiovascular health by estimating your "vascular age." 

They also explore how targeted interventions—like lifestyle changes, supplements, and medications—may help improve—and even reverse—vascular age.

This week, Dr. Kahn breaks down new research on dementia risk, including the roles of high blood pressure and early menopause. He looks at conflicting studies on red meat and ApoE4, which pretty much sums up nutrition science: one study says yes, another says absolutely not. For now, limiting red meat—especially processed—is still the safest move.

He also covers the risks of skipping breakfast, calcium CT scoring for elevated lipoprotein(a), tooth loss and heart disease, long-term clopidogrel use after stents, ultraprocessed foods, Repatha and statins, Cleerly AI scans, micro-exercise breaks, and why elevated TMAO may...

The replay of the 4th Reversing Heart Disease Summit is going on now. Register here: drtalks.com/summits/reversing-heart-disease

This week, Dr. Kahn addresses the newly published 2026 guidelines for the management of hyperlipidemia (high cholesterol), which will be studied and used by medical professionals all over the world. The top 10 takeaways are presented and are similar to the approach used at the Kahn Center for over a decade.

Other topics include the challenge of staying vegan, the influence of cold temperatures on aortic dissection, the development of clogged arteries after a normal heart artery CT...

The 4th Reversing Heart Disease Summit began March 7, 2026. There will be a replay available, and the event is free to attend online. Register here: drtalks.com/summits/reversing-heart-disease

This week, Dr. Kahn addresses the recurring posts on social media about nattokinase supplements as a "powerhouse" for reversing atherosclerosis. Is there new data? Is it powerful? Would mainstream medicine accept it? Should you use it? These questions and more are addressed. 

Other topics include the risks of sleep apnea with insomnia, sleep duration and glucose control, possible risks of spermidine, and the happy feeling that eating f...

Join Dr. Kahn for the 4th Reversing Heart Disease Summit beginning March 7, 2026. The event is free to attend online. Register here: drtalks.com/summits/reversing-heart-disease

This week, Dr. Kahn reviews new research examining the connection between red meat consumption and the risk of diabetes, elevated cholesterol, and cancer. He also discusses findings from a large study showing that vegetarian diets are associated with a lower risk of several types of cancer. 

Additional topics include emerging treatments for Lipoprotein(a), the role of coronary CT angiography in women and in individuals with a family history of h...

This week, Dr. Kahn discusses his current health challenge: a leaky mitral valve due to mitral valve prolapse, a condition of unknown cause that is unrelated to lifestyle or diet. He reviews data on mitral valve surgery, comparing repair to replacement, as well as the current availability of robotic surgery and its advantages. He plans to keep the Heart Doc VIP community updated on his status and is feeling great day to day.

Short topics this week include wine, olive oil, plant-based diets for breast cancer, Life's Essential 8, the health of babies raised in vegan families, and...

This week on Heart Doc VIP, Dr. Joel Kahn takes a deep dive into one of the most influential research projects in cardiovascular history: the Framingham Heart Study. Launched in 1948 and still going strong, this landmark study helped identify many of the risk factors we now take for granted, including smoking, diabetes, high cholesterol, high blood pressure, obesity, and physical inactivity. Much of what modern cardiology considers "common knowledge" about prevention started in Framingham.

Dr. Kahn also explores practical and emerging topics in heart health, including the role of magnesium and berberine supplementation, how to approach both...