Infertile AF: Infertility and Modern Family Building through ART

For Infertile AF’s 400th episode, Ali welcomes singer-songwriter Christina Perri for a heartfelt conversation about her family-building story, pregnancy loss, and turning grief into advocacy. She also talks about her three amazing daughters, and the beautiful sign she got recently from her girl, Rosie. Christina shares why she’s fighting to make a blood test part of routine prenatal care, what she wants other families to know, and how you can help her right now.

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THE WORK OF ART BOOK SERIES

Ali's Children's Book Series about IVF, IUI and Family Build...

This week, Ali revisits her conversation with Colorado lifestyle blogger Dani Wade, aka @dwbella, with a wonderful update: Dani is finally pregnant.

When they originally spoke, Dani was four years into her infertility journey and still in the thick of it. She opens up about failed IUIs, hormone fluctuations, surgery, and the heartbreak of trying to build a family without knowing what comes next. Dani also shares the tough conversations she and her husband have had, why the responsibility can feel like it falls entirely on the woman, and the importance of giving yourself permission to take...

What happens when two guys meet, talk for eight hours straight on their first night together, fall in love, and decide to build the family they've always dreamed of? Well, it's quite the story. And this week, Ali is getting all of it.

Ali is joined by George and Mike, husbands, dads, and the founders of Families Out Loud, a nonprofit family-building community and traveling conference dedicated to making the path to parenthood through assisted reproduction safer, more understood, and a whole lot less lonely. And not just for LGBTQ+ families, but for every family, and every...

What happens when becoming an egg donor changes the entire trajectory of your life?

This week on Infertile AF, Ali is joined by Katy Encalade, President and CEO of Egg Donor & Surrogate Solutions, who has spent nearly 20 years helping more than 2,000 intended parents grow their families through egg donation and surrogacy. But Katy's connection to this work is deeply personal. Before she ever had children of her own, she became an egg donor, an experience that would ultimately shape her career and her entire life. She later became a mom of three and a surrogate. Katy shares...

This week on Infertile AF, Ali sits down with Jarret Zafran, Founder and Executive Director of Brownstone Surrogacy, whose path into the surrogacy world started not as an agency owner, but as an intended parent himself.

Jarret shares his personal journey to fatherhood through surrogacy and how experiencing the process firsthand ultimately inspired him to create Brownstone Surrogacy. He talks about meeting his husband, what it feels like to be an intended parent, the highs, the uncertainty and the enormous amount of trust involved, and how those experiences shaped the kind of agency he wanted to build.<...

In this special Listen Again episode of Infertile AF, Ali revisits her conversation with Savannah Bisby, the voice behind @infertilityfriends, whose journey to motherhood has included endometriosis, five IUIs, pregnancy loss, and years of navigating infertility.

When Savannah first joined Ali, she was still very much in the middle of her story, sharing openly about the physical and emotional toll of infertility, loss, treatment, and the uncertainty of not knowing how—or when—her family-building journey would end.

Now, there’s an incredible update: Savannah is pregnant.

With that joyful news finally out in the...

Today’s episode is a really special one because we’re taking you behind the scenes of Petri Dish Princess—the newest book in Ali's Work of ART children’s book series—and Ali is joined by the actual Petri Dish Princess herself, Elizabeth Carr.

Elizabeth was the first baby born through IVF in the United States, and for more than four decades, her story has been told in headlines, history books and news clips. But we wanted to tell it in a completely different way: for kids.

In this episode, Elizabeth and Ali talk about how...

Today’s episode features the women behind SHOW ME THE LINE, a new documentary following the lives of four women in the aftermath of the 2024 Alabama Supreme Court decision granting personhood status to embryos. When the Alabama ruling disrupts access to IVF, acclaimed journalist and visual artist Abbey Crain has already been in fertility treatment for over 5 years. Overnight, her dreams of motherhood
— and her embryos— are out of reach. But Crain refuses to surrender her creative power. With a pen and paintbrush, she embarks on a journey to honor fellow patients. Driven to celebrate portraits of everyday people and ampl...

Today’s guest is Yesenia Lemus, a three-time surrogate and the Director of Surrogate Services at Brownstone Surrogacy. Yesenia’s surrogacy story actually started on the sidelines of her kid’s swim team, when she met another mom who was pregnant as a surrogate and thought, Wait—I could do that. Her first journey happened during COVID, when she carried twins for intended parents in California. She talks about the bond she formed with them, how she explained surrogacy to her own kids, and why she sees it as such a powerful act of generosity. She and Ali also get into...

Today's episode is a Listen Again favorite, and we couldn't think of a better one to bring back because Keri Croft is an absolute badass. Keri is an infertility, pregnancy loss, and surrogacy advocate whose path to parenthood spanned an incredible 16 years. Her story includes multiple miscarriages, IVF, a balanced translocation diagnosis, the heartbreaking decision to undergo a termination for medical reasons after learning her daughter Angel was missing part of her cerebellum, and the devastating losses of two more daughters, Hope and Jade. Keri shares how infertility tested every part of her life and marriage, what ultimately led...

Ali's guest today is Jess Mayhugh, a writer and editor who spent nearly a decade trying to have a baby before the arrival of her son, Cole. Jess's journey includes multiple miscarriages, rounds of IVF, several reproductive surgeries, and the unimaginable heartbreak of losing her newborn daughter, Lucy. On this episode, Jess opens up about navigating it all. It's a story of profound loss, incredible resilience, and massive love.

Jess co-founded a newsletter called Folly, which includes personal essays, expert interviews, and service journalism around family building.

IG: @jessmayhugh @followfolly

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You might know today’s guest, Alease the Embryologist, from social media, where she somehow manages to educate, empower and entertain while breaking down what’s actually happening behind those mysterious IVF lab doors. Alease is incredibly smart and refreshingly real, and today, Ali and Alease get into ALL of it—including her own decision to freeze her eggs while happily married, because she’s still on the fence about building a family, and why she chose to freeze eggs instead of embryos with her husband. Alease also takes us behind the scenes of the embryology lab, sharing a day in t...

Today, Ali sits down with Kate Ryan, founder of Story of Us, for a heartfelt conversation about infertility, resilience, and redefining what family can look like.

Kate shares her deeply personal path to parenthood, beginning with IUI, moving through IVF, and ultimately building her family through donor conception. She opens up about the emotional highs and lows of treatment, the unexpected twists along the way, and what it took to embrace a future that looked different than the one she originally imagined.

Kate also talks about why she founded The Story of Us, a platform...

With soccer on everyone’s mind right now, this felt like the perfect time to bring back one of our most unforgettable episodes.

This week on Infertile AF, we’re re-sharing Ali’s powerful conversation with soccer legend Carli Lloyd. Carli is a former pro soccer star, two-time World Cup champion, two-time Olympic gold medalist, and one of the fiercest competitors to ever play the game. And in this episode — which originally aired two years ago — she opens up about something far more personal: her long and difficult infertility journey.

Carli shares what happened when she and he...

Today's guest is Danielle Melfi, the CEO of RESOLVE: The National Infertility Association. Danielle brings such a unique perspective because she's not only leading the nation's largest infertility advocacy organization—she's also been a fertility patient herself. In this episode, she opens up about her own egg-freezing journey and how that experience continues to shape the way she advocates for millions of people navigating family building today.

Ali and Danielle talk about what RESOLVE is working on right now, why fertility treatment is still financially out of reach for so many people, and the real work being do...

Today’s episode is a really special one because Ali is sitting down with three of her favorite people in the world: Helen, Aaron, and Blake—the real-life family behind her “Work of ART” children's book, Beautiful Bird.

If you’ve read the book, then you already know a little bit about Jack Bird, the incredible boy at the center of the story. And today, you’re going to hear the real origin story. This is a conversation about love, friendship, family building, and creating a family that looks different than what many of us grew up seeing—but i...

On this episode, we're talking about something that affects millions of fertility patients—but that almost nobody talks about until the bill shows up: reproductive tissue storage.If you have embryos, eggs, or sperm in storage, you know the drill. Every year, another invoice arrives. Maybe it's $600. Maybe it's $800. Maybe it's over $1,000. Most people just pay it because they assume that's the cost. But what if it isn't? Ali’s guest today is Charlie Boyer, CEO and Co-Founder of Generations CryoVault, and he's on a mission to shake up an industry that he believes has gotten way too comfortable char...

Today’s guest is Cory Allen—a former police officer, longtime U.S. Secret Service Agent who spent years protecting Michelle Obama, author, dad, and advocate for LGBTQ+ family building.

You may know Cory from his memoir, Breaking Free, where he shared his journey as a gay Secret Service Agent. Now he’s written a children’s book called Dada Takes a Trip, inspired by the very real emotions that come with leaving your child behind for a work trip—and helping kids understand that love doesn't disappear just because a parent is away.

In this episo...

Model, entrepreneur, and new mom Analicia Chaves (aka Ana Montana on socials) joins Ali to share the fertility journey that led her to motherhood—and the mission that grew from it.

Ana opens up about her experience with infertility and IVF, revealing how little she knew about fertility challenges before facing them herself. "I didn't even know infertility was a thing until it happened to me," she says. While her friends seemed to be getting pregnant naturally, Ana found herself navigating a world of uncertainty, fear, and overwhelm.

She shares her struggles with endometriosis, heavy bl...

Angela Rastegar knows firsthand just how overwhelming — and expensive — the family-building journey can be. Before co-founding Sunfish, she spent years working in healthcare and tech while navigating her own fertility journey, including egg freezing and later, embryo creation.

Now, she’s turned that experience into her life’s work. Through Sunfish, Angela is helping make fertility and family-building care more accessible with emotional support plus real financial savings — we’re talking $8,000 to $18,000 per cycle. And the best part? Sunfish is built for anyone on any path to parenthood.

In this episode, Angela opens up to Ali about th...

LISTEN AGAIN

NBC News correspondent and former CNN entertainment reporter Chloe Melas joins Infertile AF for an incredibly honest conversation (from 2020) about the emotional toll of infertility, navigating IVF in the public eye, and the pressure so many women feel to “do it all” while struggling behind the scenes. Chloe opens up about her two-year journey to parenthood with husband, Brian, after diagnoses of low ovarian reserve and male factor infertility. She shares the heartbreak, uncertainty, and resilience that ultimately led to the birth of both of their sons through IVF — plus what she wishes more people unders...

This week on Infertile AF, Ali sits down with comedian, creator and storyteller Candice Guardino for a heartfelt and deeply honest conversation about infertility, IVF, pregnancy loss, endometriosis, and finding light through the hardest moments. Candace opens up about freezing her eggs, navigating fertility treatment while building her career, the emotional toll of trying to conceive, and how comedy became both a coping mechanism and a way to connect with others.

They also talk about the pressure women feel around timelines, relationships, and motherhood, plus the importance of telling these stories out loud. Equal parts funny, vulnerable...

Today on Infertile AF, Ali is talking to Kat — better known online as @theivfbaby. And yes, that’s exactly what it sounds like: Kat was conceived through IVF herself, long before people were openly talking about infertility, assisted reproduction, or what it means to grow up as an IVF-conceived person.

Now, she’s using TikTok and Instagram to normalize IVF from a perspective we rarely hear — the IVF-conceived person herself. Through myth-busting videos and answering the questions people are sometimes too afraid to ask, Kat is helping break down stigma in a big way.

In this epi...

Today’s guest is someone so many of you already know and love from IG and TikTok—Loren Rosko—and her story goes way beyond the viral song parodies and infertility anthems. Loren started making TikToks during COVID, at a time when so many of us were feeling isolated and searching for connection. What began as a creative outlet quickly turned into something much bigger—a space where she could share everything she was going through in life, including navigating infertility. In this episode, Ali and Loren get into all of it, including PCOS, miscarriage, IVF, loss, what it feels li...

What if the products you use every single day—your water bottle, your skincare, your food containers—are quietly impacting your fertility? In this episode, Ali dives into The Plastic Detox on Netflix—the documentary that has everyone questioning what’s in their homes (and their bodies). Ali is joined by Dr. Shanna Swan, one of the world’s leading researchers on environmental exposures and reproductive health—and a featured expert in the film. Ali and Dr. Swan talk about how the doc came to be, the real link between plastics, chemicals, and fertility, and how you can make realistic, n...

On this week’s episode, Ali sits down with an icon and true pioneer in the infertility space: double board-certified REI and infertility warrior, Dr. Natalie Crawford. Natalie opens up about her own journey through four pregnancy losses before welcoming her two children—and what it’s like to be on both sides of the stirrups as both doctor and patient. She shares the unique challenge of navigating infertility as someone who “knows too much,” and how that knowledge can be both empowering and overwhelming.

They also talk about how Natalie has built a massive, trusted community by showing...

Today’s guest is Jackie Hutson, who opens up about experiencing multiple miscarriages, navigating uterine challenges, and the toll infertility can take on your relationship and sense of self. Ali and Jackie talk about what it means to keep moving forward after loss, and how those experiences shape you in ways you never expect. Now a mama of two boys, Jackie has created something meaningful: Piper & Mint, a groundbreaking pajama brand that's perfect for the fertility community—because she knows just how important comfort and care are during some of life’s hardest moments.

For more, go to Pip...

Today, Ali is bringing back a special encore episode with the incredible Sheinelle Jones — an award-winning journalist and co-host of Today with Jenna & Sheinelle. In this powerful conversation from December 2021, Sheinelle opens up about her personal experience with miscarriage and infertility, sharing the heartbreak, the resilience, and the honesty. She also talks about her documentary, "The Stories We Tell: The Fertility Secret." If you missed this one the first time — or need it today — make sure to give it a listen.

EPISODE SPONSORS: 

THE WORK OF ART BOOK SERIES

Ali's Children's Book Series about IV...

Today, Ali is talking to Emily Westerfield — a surrogate to nine babies and mom of three — who has carried a total of twelve healthy pregnancies… six boys and six girls. Emily has delivered nine babies through surrogacy, helping other families grow in the most extraordinary way. But as you’ll hear, this journey has not come without high highs, low lows, and everything in between. Ali and Emily talk about the happiest parts — including when she decided that becoming a surrogate was her calling, as well as the hardest parts — including miscarrying a surrogate pregnancy at 19 weeks — and what it actually tak...

Cheri Bergeron’s path to motherhood is anything but simple—and that’s exactly why her story is so powerful. Cheri is the author of Mission: Motherhood, and in this episode, she shares with Ali the full, unfiltered journey: from devastating pregnancy loss to IVF, to donor conception, and ultimately becoming a mom to her two children.

But Cheri didn’t just navigate the system—she challenged it. Cheri and Ali also talk about the lawsuit that helped reshape what family-building can look like for women everywhere, and why her experience has become a rallying cry for so many tr...

Today’s episode is a special one — it’s a replay of Ali's 2023 conversation with Dr. Lucky Sekhon. Lucky is a board-certified reproductive endocrinologist, infertility specialist, and OB-GYN at RMA of New York. She’s also one of the most trusted voices on social media and TV when it comes to fertility, IVF, and reproductive health, breaking down complicated topics with clarity, compassion, and actual science.

In this conversation, Lucky opens up about her own family-building journey — including how, when it came time to start her family, she chose to create embryos and go through IVF herself. Ali and Lu...

What happens when one of the most disciplined bodies in the world can’t do the one thing everyone assumes it should? On this episode -- one of our most downloaded of all time -- Ali sits down with Mathilde Froustey, principal dancer at the San Francisco Ballet and widely considered one of the most extraordinary dancers in the world.Born in Bordeaux, France, Mathilde began dancing at just nine years old, training at the prestigious Marseille National School of Ballet and the Paris Opera Ballet School before rising to the top of the international ballet world. Onstage, her bo...

It's Endometriosis Awareness Month. Ali's guest this week, Holly Abel, was eleven years old when her debilitating periods started. For decades, doctors told her it was “normal.” That she was dramatic. Hormonal. Sensitive. It wasn’t normal. In early 2023, Holly was finally diagnosed with severe stage 4 endometriosis — affecting multiple organs throughout her body. Shortly after, she experienced a miscarriage. In December 2023, she underwent major surgery. Then in March 2024, after a routine HSG, everything began to unravel. By early May, she was in septic shock and given a 10% chance to live. In July, a total hysterectomy saved her life… and ended her...

Today, Ali talks to Barbara Ginty, host of the Future Rich podcast, for a special crossover episode to share her deeply personal fertility journey — and to talk honestly about the emotional and financial realities of IVF. Barbara froze her eggs in her 30s, not knowing exactly when or how she might use them. Seven years later, she returned to those frozen eggs and went through IVF — and now, as this episode airs, she’s on the brink of welcoming her first baby. Barbara shares what it was like to trust a decision she made years earlier, the uncertainty of the pr...

Today’s guest is Alexis Allegra, and her path to motherhood is one of those stories that reminds you just how many twists and pivots this journey can take. Alexis met her person later in life and, like so many of us, thought, okay — let’s go, let’s start trying right away. But what followed was nearly three years of fertility treatments… chemical pregnancies… failed IVF transfers… and a whole lot of heartbreak and regrouping. In her mid-40s, when things weren’t unfolding the way she’d imagined, Alexis made a brave pivot to embryo donation — a decision that ultima...

If you're considering freezing your eggs: This one's for you. Fashion influencer and writer Lily Montasser built her platform sharing effortlessly cool style, NYC life, and sharp, honest storytelling. But recently, she opened up about something far more personal: her decision to freeze her eggs. Instead of keeping it private, Lily brought her followers along for the ride — partnering with Extend Fertility for her treatment, documenting the appointments, the hormones, the doubts, and the unexpected empowerment of taking control of her fertility timeline. In this episode, Ali and Lily talk about what it really feels like to make proactive ch...

On today's episode, content creator and mama of three Ruby Smoot gets real about the parts of infertility and pregnancy after infertility we don’t talk about enough — the mental health spiral, the obsessive thoughts, the fear, and the quiet, heavy darkness that can creep in while you’re trying so hard to become a parent. In this deeply candid conversation, Ruby opens up about pregnancy after infertility while battling OCD and intrusive thoughts, navigating severe nausea called hyperemesis gravidarum (HG), and what it felt like to hold hope and despair at the same time, and how becoming pregnant didn’t...

Today’s guest is Rachel Swanson — MS, RD, LDN — one of the most in-demand nutritionists in the country, known for helping people optimize performance using deeply science-backed, totally personalized care. She’s also the author of the brand-new book Trying!: A Science-Backed Plan to Optimize Your Fertility. On today's episode, Ali and Rachel flip the fertility conversation on its head with what Rachel calls Fertility 2.0 — a proactive, preventative approach that goes way beyond eggs and sperm to focus on the whole body: your gut, metabolism, sleep, oral health, even your partner’s kissing hygiene (yes, really). This convo was originally a...

On this episode, Ali is joined by Jared Walker—author of The Empty Nest and founder of the non-profit Dollar For—for one of the most raw and important conversations we’ve had in a while. It's so great to hear a guy's perspective on infertility, and Jared and his wife are still in the thick of it. There’s no neat ending here, no bow tied on the story—and that’s exactly why this conversation matters. Ali and Jared talk about how he and his wife grew up together (he's best friends with her brother); what happened when they st...

This episode is a powerful conversation pulled from Fertility Rally Live in November 2025,, where we gathered an incredible panel to talk candidly about surrogacy — from every angle.Moderated by Jessie Jaskulsky of Surrogacy Simplified, the panel includes surrogacy mama Sarrah Strimmel Bentley, experienced surrogate Emily Westerfield, and surrogacy mama Alexandra French of The Surrogacy Foundation for an honest, nuanced discussion about what surrogacy really looks like — emotionally, logistically, ethically, and financially. Covered in the chat: