Biohacking Beauty: The Anti-Aging Skincare Podcast

Think your SPF 50 is giving you extra protection? Not exactly.

In this episode of Biohacking Beauty, we’re breaking down the truth about sunscreen—because what you don’t know might be damaging your skin. From hidden ingredients that mess with your microbiome to why higher SPF might actually give you a false sense of security, this is your no-BS guide to smarter sun protection.

We also get into how filters like oxybenzone and avobenzone can impact your skin barrier, why “broad spectrum” doesn’t always mean full protection, and why texture, finish, and reapplication matter just...

What if your breakouts, fine lines, and melasma weren’t about finding the “perfect” product, but fixing what’s happening under the surface?

In this episode, we’re joined by Jamie McGuire, functional aesthetician and founder of Jamie Ann Aesthetics, to explore what truly personalized skincare looks like—and why most routines miss the mark.

We unpack how internal stress, diet, hormones, and nervous system dysfunction show up on your face, why you shouldn’t chase quick fixes, and how to build an anti-aging protocol that actually works. We also discuss the most common skincare mistakes keepi...

What if the missing key to youthful skin, pain-free movement, and true longevity wasn’t in a serum or surgery, but in your fascia?

In this episode, we’re joined by Ashley Black, fascia expert, innovator, and creator of the FasciaBlaster®, to explore why this often-ignored system may be the body’s most powerful regenerative tool.

We break down how fascia impacts skin elasticity, blood flow, and even stem cell signaling, why popular beauty devices may be doing more harm than good, and how fascia remodeling can reverse stiffness, stagnation, and aging at every level. 

We...

What if reversing joint pain, skin aging, and inflammation wasn’t about more supplements, but about better signals?

In this episode, we’re joined by Dr. Ross Carter, a regenerative medicine expert and founder of the Young For Life protocol, to explore how stem cells, exosomes, peptides, and biologics are shaping the future of aging.

We unpack the science of cell signaling, inflammation, and tissue regeneration, and why most people approach regenerative medicine all wrong. We dive into how perinatal stem cells work, the truth about exosomes and MMPs, why enzyme neutralization matters more than coll...

What if the secret to glowing skin, a sharper brain, and a revived sex drive isn’t more skincare, but hormone replacement therapy?

In this episode, we’re joined by Karen Martel, certified hormone specialist and founder of The Hormone Solution, to unpack the misunderstood science of beauty and aging. From pheromones and libido to collagen and facial structure, we explore how estrogen, progesterone, and testosterone shape how you look, and how you feel.

We break down how hormone loss affects everything from your skin’s elasticity to your body composition, and why most women are be...

What if the key to younger skin, stronger muscles, and a sharper mind isn’t more cardio—but more connection?

In this episode, we’re joined by Kristin McGee, a nationally recognized yoga and wellness educator who bridges classical practice with modern science to help people live, move, and age better, inside and out.

We unpack the science of mindful movement and its direct impact on aging. From her days on 30 Rock to launching Peloton’s yoga platform, Kristin shares what 30+ years of teaching has taught her about resilience, skin vitality, and aging well.

We div...

What if your skin issues—breakouts, dullness, inflammation—weren’t random, but deeply connected to your cycle?

In today’s episode, we are sharing a recent conversation we had on the Revital Health Podcast with Jodi Duval. We dive into something I feel incredibly passionate about: how each phase of the menstrual cycle affects our skin, and how aligning our skincare rituals with those hormonal shifts can create real, visible change.

We also talk about Anastasia’s (YG Co-founder) personal postpartum skin struggles, why traditional skincare advice often fails women, and the biohacking strategies I use to sup...

What if your skin problems aren’t skin-deep at all, but rooted in your gut?

In this episode, we’re joined by gut health expert Joni Laiho to explore one of the most overlooked yet powerful connections in skin longevity: the gut-skin axis. If you’re dealing with adult acne, stubborn inflammation, accelerated aging, or skin that just doesn’t bounce back, this conversation is for you.

We break down how gut dysfunction silently drives skin issues, the early signs your gut is leaking into your face (literally), and the doctor-backed protocols that can rebuild your ski...

In this episode, we break down some of the most viral skincare trends you see all over Instagram and TikTok, face ice baths, jelly eye patches, salmon sperm facials, red light masks, Morpheus 8, niacinamide overload, and more.

But here’s the thing: just because a trend is everywhere doesn’t mean it works, or that it supports your skin long-term.

We don’t hype or bash blindly, we give you the science-backed truth so you can make smart, informed choices about what’s actually worth your time (and money). From understanding why face ice baths aren’t t...

What if your skincare routine could actually trigger your body’s built-in anti-aging pathways? Most products just treat the surface, but aging starts much deeper, at the cellular level.

In this episode of the Biohacking Beauty Podcast, I’m talking with Dr. Melissa Cano, Director of Science at Longevity Labs and one of the smartest voices out there when it comes to spermidine, autophagy, and cellular health. Melissa has spent years teaching practitioners and biohackers how polyamines like spermidine can activate the body’s natural cleanup process, support mitochondrial health, and actually help cells function younger.

We g...

In today’s episode, Anastasia and I are diving into a topic that’s on everyone’s lips—Botox. It’s become a standard in many beauty routines, but the truth is, Botox isn’t as simple as it’s made out to be. While it can smooth out wrinkles, repeated use can actually change the way your face moves and functions, leading to long-term issues like muscle atrophy and loss of natural expression.

We’re not here to scare you, but to arm you with the knowledge you need to make informed, empowered decisions about your skin. We’re brea...

In today’s episode, Anastasia and I are tackling a topic that doesn’t get enough attention in skincare: your neck and chest. These areas age faster than your face, and most people completely overlook them in their routines. But why? The skin here is thinner, less hydrated, and more vulnerable to environmental stress. Gravity, sun damage, and even posture all contribute to crepey skin and sagging.

We’re diving into the biology of why the neck and chest age faster and what you can do about it. We’ll talk about essential strategies to keep your skin fir...

Hey everyone, welcome back to Biohacking Beauty! In today’s episode, we’re diving into red light therapy, one of the most science-backed tools for skin rejuvenation. But not all devices are created equal. I’ll break down the top five things you need to know before investing in a red light therapy device.

We’ll start with the science behind red light therapy, from wavelengths to irradiance, and how these factors impact skin health. I’ll also explain why certain devices fall short and how to identify the ones that truly deliver results. Plus, I’ll touch on the...

Hey everyone, welcome back to Biohacking Beauty! In this episode, we’re diving deep into a truth most skincare routines ignore: your environment might be aging you faster than time ever could.

We start with a story of two identical twins, same genes, same skincare habits, but drastically different aging outcomes. Why? One lived surrounded by clean nature. The other, in an urban jungle filled with air pollution, EMFs, blue light, and toxic stress. The difference wasn’t just visible, it was cellular.

In this episode, I explore how environmental stressors silently sabotage your skin by d...

Most people think menopause is just about hot flashes and mood swings—but what if I told you it’s actually one of the biggest drivers of skin aging? From collagen loss to increased sensitivity, breakouts, and inflammation, hormonal shifts can make you look older, faster. And yet, no one is talking about it.

To uncover the real impact of menopause on skin health (and what you can do about it), I’m joined by Dr. Jessica Shepherd, an OB-GYN, menopause expert, and founder of Sanctum Med & Wellness. She’s on a mission to rewrite the menopause narrativ...

Your skin is a reflection of your cellular health—but what if you could influence it on a deeper level? Red light therapy (photobiomodulation) is changing the way we think about aging, collagen production, and inflammation. In this episode of the Biohacking Beauty podcast, Amitay Eshel and  Anastasia Khodzhaeva, co-founders of Young Goose Skincare, break down how red light therapy impacts skin longevity, from boosting collagen to reducing inflammation. They explain what determines individual results, the common mistakes people make, and how to get the most out of this powerful technology.

But here’s the truth that not e...

Welcome back to Biohacking Beauty! In this episode, we tackle the controversial topic of Botox and explore effective alternatives for those seeking more natural approaches to youthful skin. Young Goose co-founder Anastasia Khodzhaeva opens up about her personal experience with Botox treatments and why they didn't work for her, while we discuss the science behind various alternatives.

Rather than demonizing Botox, we examine both sides of this polarizing beauty topic, offering insights for those who use Botox and those looking for different options. From peptides and cellular repair compounds to professional treatments and at-home techniques, we break...

Hey everyone, welcome back to Biohacking Beauty! Today, we’re exploring one of the most fundamental mechanisms of aging—telomeres. These nucleotide sequences at the ends of our chromosomes act as protective caps, preserving DNA integrity during cell division. However, each time a cell replicates, telomeres shorten, eventually leading to cellular senescence, dysfunction, or apoptosis.

In this solo episode, I’m breaking down the molecular mechanisms behind telomere shortening, how factors like oxidative stress, inflammation, and metabolic dysfunction accelerate the process, and, most importantly, what we can do to slow or even reverse this decline.

We’ll...

Today, we’re diving into a discovery that could reshape how we think about aging—C15, a newly identified essential fatty acid that plays a crucial role in cellular resilience, inflammation control, and longevity.

For decades, we’ve been told to avoid saturated fats, but what if that advice led to widespread nutritional deficiencies? Dr. Stephanie Venn-Watson, a veterinary epidemiologist and co-founder of Fatty15, uncovered C15’s role in strengthening cell membranes, reducing oxidative stress, and even influencing epigenetic aging—all from studying long-lived Navy dolphins.

In this episode, we break down how C15 protects against ce...

For years, skincare has been about quick fixes, hydration, plumping, and surface-level treatments that make your skin look better but don’t actually reverse aging. But what if the future of skincare wasn’t about temporary effects, but about reprogramming your skin at the cellular level?

In this episode of Biohacking Beauty, I take a deep dive into longevity skincare and the science behind true skin rejuvenation. We’re going beyond the outdated skincare model and breaking down the Skin Longevity Matrix, a biohacking approach designed to restore youthful function from within.

I cover...

Today, we’re diving into something that goes way beyond skincare, how your skin is actually a powerful window into your overall health and longevity. Most people think of aging as just wrinkles and fine lines, but the reality is that what’s happening on the surface is a direct reflection of what’s going on at the cellular level.

To explore this, I’m joined by Nick Engerer, a longevity scientist and the founder of A Longer Life, where he helps people take a data-driven, strategic approach to optimizing health and aging. Nick’s work is all about...

For years, skincare has focused on surface-level solutions, moisturizers, retinol, collagen creams… but what if we told you that true skin rejuvenation starts at the cellular level? Traditional skincare is designed to mask aging, but new research in longevity science reveals that the root causes of aging go much deeper.

In this episode of Biohacking Beauty, I break down the real drivers of skin aging, from mitochondrial dysfunction and NAD decline to epigenetic shifts, senescent cells, and impaired autophagy. I also discuss why most anti-aging products don’t actually reverse aging, and how cutting-edge biohacking ingredients like NAD+...

Welcome back to Biohacking Beauty! Today, we’re diving into the cutting-edge science of biological vs. chronological aging and how epigenetic testing is revolutionizing the way we understand skin longevity. Aging isn’t just about the number of birthdays you’ve had—it’s about how your cells are aging at the molecular level. And now, thanks to advancements in epigenetics and AI-driven diagnostics, we can measure and even influence that process.

In this episode, I sit down with Hannah Went, an expert in biological age testing and the Director of Operations at TruDiagnostic, a leading epigenetics company. W...

Have you ever wondered why traditional sunscreens aren’t enough to protect your skin from all forms of light damage? In this episode of Biohacking Beauty, I’m sitting down with Jamie McGuire to break down the truth about blue light exposure, SPF, and effective melasma protocols.

We dive into why hyperpigmentation often worsens with artificial light exposure, the importance of full-spectrum protection, and how Young Goose’s innovative formulas address common skin concerns like melasma, sensitivity, and inflammation. Plus, we tackle the "clean beauty" debate—are some ingredients being unfairly criticized?

Jamie McGuire is a skinca...

Most people don’t think about their skin until they have to. The reality is, by the time we notice fine lines, dullness, or inflammation, deeper processes have already been at play for years. But what if your skin isn’t just reflecting aging? What if it’s reflecting your overall health, stress levels, and even brain function?

In this episode of Biohacking Beauty, I sit down with Dr. Scott Sherr to uncover the fascinating connection between your skin and brain, a relationship most people don’t even realize exists. This conversation originally took place on The Smarter...

Have you ever wondered why some skincare products seem to work wonders for some people, while others see little to no results? In this episode of Biohacking Beauty, I’m sitting down with Jamie McGuire, a skincare consultant with over 15 years of experience, to break down the truth behind personalized skincare and why a one-size-fits-all approach just doesn’t cut it.

We dive into the difference between traditional retinol and bio-retinol, the science of vitamin A delivery systems, and how the right formulations can repair your skin without triggering irritation. Plus, we tackle the “clean beauty” debate—are some i...

Many of us think of plastic surgery as a drastic, last-resort solution, but what if the secret to natural, long-lasting results isn’t about doing more, but doing less? The field of facial rejuvenation has evolved dramatically, moving away from overly invasive procedures and toward minimally invasive, high-impact techniques that enhance both appearance and skin health.

In this episode of Biohacking Beauty, I sit down with Dr. Cameron Chesnut, a pioneer in holistic plastic surgery, to discuss how strategic, small interventions can create incredible, natural-looking results. Dr. Chesnut explains why traditional plastic surgery approaches are outdated, how pe...

Have you ever stopped to think about the invisible forces that are silently aging your skin—and how the right tools can reverse the damage? In this episode of Biohacking Beauty, I’m diving into a fascinating conversation with Jamie McGuire, a skincare expert and passionate advocate for long-term skin health.

We explored the often-overlooked role of the skin barrier in maintaining youthful, healthy skin and why NAD, the molecule of cellular repair, is a game-changer. From breaking down what “leaky skin” really means to revealing how inflammation and environmental stressors disrupt your skin’s ability to heal, this...

Many of us chase radiant, youthful skin by investing in expensive products, but I’ve learned that the secret to lasting results often lies beneath the surface—literally. Your gut health plays a pivotal role in your skin’s appearance, influencing everything from hydration to inflammation and even premature aging. The more I dive into this topic, the more I realize how understanding the gut-skin connection is key to unlocking healthier, glowing skin.

In this episode of Biohacking Beauty, I sit down with Melissa Boloña, founder of The Beauty and the Broth, to discuss how gut health...

We all want to live longer, healthier lives—but what if the key to longevity isn’t just about doing more, but understanding how your body adapts to stress? From navigating everyday challenges to the science of hormesis, the small, intentional stressors we introduce can either build resilience or break us down.

In this episode of Biohacking Beauty, I sit down with Dr. Nasha Winters, a pioneer in metabolic oncology and someone I’ve admired for years, to unpack the real story behind resilience and how it ties into beauty, health, and longevity. We dive into how your b...

Most of us have heard of exfoliation, and you may already be incorporating this step into your routine. But did you know that exfoliation plays a pivotal role in keeping your skin radiant and healthy? Think of exfoliation as prepping a canvas before painting. Just like you wouldn't apply fresh paint on a wall without preparing it first, you shouldn't apply skincare products on a layer of dead skin cells. 

Welcome to another episode of the Biohacking Beauty podcast brought to you by Young Goose Skincare! In this episode, host Amitay Eshel, the CEO of Young Goose, d...

Many of us unknowingly harm our skin with habits we think are helpful. Over-exfoliating, using the wrong products, or skipping sunscreen altogether can damage your skin barrier, leading to dryness, sensitivity, and even premature aging. If your skincare routine feels overwhelming—or worse, ineffective—it might be time to simplify and get back to the basics.

In this episode of Biohacking Beauty, I sat down with Dr. Mary Alice, a dermatologist with nearly two decades of experience, to dive into how to avoid these common mistakes. We talked about the power of skin minimalism, why your skin barr...

Do you ever feel like your busy life keeps sabotaging your health and skincare goals? Whether it’s travel, work stress, or just too many options to choose from, these roadblocks can leave you stuck and overwhelmed. But what if there was a way to cut through the noise and build routines that work—anytime, anywhere?

In this episode of Biohacking Beauty, I sit down with Paul Sorbo, an entrepreneur who has spent years revolutionizing the wellness industry, to uncover how to simplify the approach to health and skincare. We dive into the real issue of decision fati...

What if your skincare routine is missing the key to truly transforming your skin—inside and out?

In this episode of Biohacking Beauty, I invite you into the often-overlooked fundamentals of skin health and longevity. From avoiding the biggest mistakes in skincare to unlocking the power of ingredients like flavonoids and perfecting your routine, this conversation is packed with actionable insights to elevate your approach to skin wellness.

I’m joined by Nerida Joy, one of the most experienced professionals in the skincare world. Together, we uncover why proper cleansing is 50% of your regimen, the dang...

Could artificial intelligence revolutionize personalized healthcare and skincare—or is its potential being overstated?

I had the incredible opportunity to join Stephanie on her Change Life Destiny Podcast to discuss one of the most fascinating topics in healthcare today: the role of AI in shaping the future of personalized health and skincare.

In our conversation, we explored how AI is being utilized to diagnose conditions, develop smarter skincare solutions, and even redefine how practitioners and patients approach health optimization. But here’s the twist—AI, as powerful as it is, can’t replace human expertise. I shared...

What if your skin holds the ultimate key to your overall longevity? Many of us focus on treating the body while overlooking how skin health directly impacts whole-body aging. From senescent cells wreaking havoc to innovative NAD therapies, there's a science to reversing skin aging and unlocking vitality.

We dive into these fascinating topics in this episode of Biohacking Beauty with guest Dr. Stephanie Gray. Together, we unpack how environmental factors drive 80% of skin aging, the revolutionary role of NAD+ in DNA repair, and how innovative skincare formulations protect against modern-day stressors like EMFs and pollution.

Have you ever wondered if your skincare could do more than just smooth wrinkles? What if it could truly transform your skin at a cellular level?

On this episode of Biohacking Beauty, I’m sharing my recent conversation with Stephanie on The Change Life Destiny Podcast Series, where I had the opportunity to dive deep into the fascinating science behind biohacking and skincare.

We explored how cutting-edge molecules like NAD and Spermidine fuel cellular repair, how environmental factors like pollution and UV exposure accelerate skin aging, and why no single ingredient can be the ultimate ma...

Can your hormones be the ultimate key to reversing the clock on aging and unlocking peak wellness? From overlooked recovery strategies to a lack of innovation in male enhancement and hormonal health, many are unaware of how cutting-edge science can drastically improve both health and confidence.

We dive deeper into these groundbreaking topics in this episode of Biohacking Beauty with guest William Moore. We also chat about how to optimize your hormones, the fascinating science behind red light therapy, and the revolutionary advancements in penile enhancement.

William Moore is a biohacking expert with over two...

What if the key to optimal skin health and overall wellness lies in how your body responds to oxygen? This week on Biohacking Beauty, I’m joined by Janelle Ardizzone, founder of Desert Moon Wellness, to unpack the multifaceted benefits of hyperbaric oxygen therapy (HBOT). Together, we explore its role in cellular healing, immune system support, and its ability to catalyze profound mind-body transformations.

Janelle and I dive into how HBOT operates as a "push system" that primes the body for healing, explaining why its real benefits often occur outside the chamber. We discuss its unique effects on...

Have you ever felt like your relationship with food is more complicated than it needs to be? What if the stress of dieting and food rules is doing more harm to your skin and overall health than you realize?

In this week’s episode of Biohacking Beauty, I sit down with Kiki Athanas to explore the science of intuitive eating and its unexpected connections to skin health. By learning to tune into your body’s natural hunger and satiety cues, you can reduce inflammation, balance hormones, and unlock your skin’s natural glow—all without the stress of restr...