Biohacking Beauty: The Anti-Aging Skincare Podcast

Exosomes aren’t just a buzzword, they’re nanoscale messengers that deliver the body’s own repair instructions. In this episode of Biohacking Beauty, we unpack the science of platelet-derived, or “vampire,” exosomes and how they go beyond conventional growth factors to target aging at its root. 

You’ll learn how microRNA inside platelet exosomes can reduce senescence signals, trigger collagen and elastin renewal, and activate autophagy for deeper cellular repair. The hosts also explore how formulation stability, ingredient compatibility, and third-party quantification make or break an exosome product. 

If you’ve ever wondered how PRP exosomes com...

What if the products you’re being told to buy are doing more harm than good?

In this episode of Biohacking Beauty, we strip it back to unfiltered opinions, no scripts, no fluff, just real talk about the ingredients and habits that get way too much attention in skincare.

We call out why certain “hero” ingredients, like high-dose niacinamide, may actually backfire with chronic use, and why collagen powders in hot coffee aren’t the miracle they’re sold as. We dig into the over-exfoliation trap, explain why protecting your barrier is the foundation for every othe...

Most people know spirulina as a superfood: a bright green powder you toss into smoothies.

But what happens when this blue-green algae becomes a skincare ingredient?

In this episode of Biohacking Beauty, we go behind the science to explain why spirulina deserves a place in your longevity routine.

We break down how its unique peptides, antioxidants, and minerals defend against oxidative stress, boost collagen, and calm inflammation, all while keeping skin hydrated and resilient. We also share how spirulina fights acne, supports barrier repair, and even offers mild UV protection.

You’ll...

What if the most popular skin treatments today are quietly accelerating aging beneath the surface?

In this episode of Biohacking Beauty, we go unfiltered, sharing the procedures we actually trust, the ones we avoid, and the rules we’re not afraid to break. 

We explain why microneedling with PRP remains the gold standard for regeneration, why red light therapy is the ultimate mitochondria hack, and how pairing it with our Ladder Serum doubles the results. We also reveal why your skin’s metabolic state, NAD+ levels, senescence, and mitochondrial function determine how well any treatment works...

What if stress isn’t the reason your hormones are crashing, what if it’s the other way around? In this episode of Biohacking Beauty, we sit down with longevity clinician Dr. Sarah Daccarett to explore how early hormone decline sets women up for stress intolerance, immune dysfunction, and accelerated aging.

We will explain why telling women to “just de-stress” misses the point, how estrogen and progesterone regulate immune balance, and why autoimmune disease skyrockets when these hormones drop. We also dive into the role of environmental toxins and birth control in shutting down protective signaling, and why most...

Why do most facial sprays feel great, but deliver nothing long term?

In this episode of Biohacking Beauty, we reveal the science behind our new Blue Peptide Spray, the first mist with a clinical dose of methylene blue, plus NAD+ precursors, GHK-Cu, and SOD. It’s designed to optimize mitochondrial energy, reduce oxidative stress, and support true skin repair.

We break down why methylene blue acts as a cyclic antioxidant, how it stacks with other longevity ingredients for visible results, and how our anti-staining technology makes it safe for daily use, even over makeup.

...

What if your collagen cream isn’t working, because your skin doesn’t have the raw materials to use it?

In this episode of Biohacking Beauty we reveal the missing half of most people’s skincare: the internal protocol. From vitamin C as a collagen cofactor (“10x harder for your skin to build collagen without it”) to the role of omega-3s in plumping skin from the inside out, this episode lays out a step-by-step supplement strategy for real skin longevity.

We break down why oral hyaluronic acid outperforms topical forms in clinical trials, why senescent...

What if the reason your skin barrier keeps breaking down has nothing to do with your products, and everything to do with the water coming out of your tap?

In this episode, Leah Vairo, Chief Brand Officer at FilterBaby, joins us to reveal how chlorine, hard water minerals, and hidden contaminants in your shower or sink accelerate oxidative stress, disrupt the microbiome, and drain your skin’s NAD⁺ reserves. We dive deep on how unfiltered water weakens keratinocyte activity, fuels irritation and redness, and speeds up visible aging. even if you’re using the best skincare.

You’...

What if the real reason your skin is aging faster has nothing to do with your skincare, and everything to do with your gut?

In this episode, Dr. Vincent Pedre, gut health expert joins us to uncover how leaky gut, dysbiosis, and hidden food sensitivities can trigger acne, eczema, redness, and premature wrinkles. We explain how gut inflammation accelerates collagen breakdown, fuels glycation, and weakens the skin barrier, and why restoring your microbiome can be more powerful than any topical cream.

You’ll discover the surprising role of pomegranate polyphenols, how certain “healthy” foods can sabota...

There’s a point where even the best skincare starts to feel like it’s not doing enough. Serums stack up, results slow down. What no one tells you is that this might not be a product issue, it might be an energy issue. Specifically, cellular energy. NAD+.

You’ll learn why NAD+ declines with age, how that leads to slower healing, collagen breakdown, and pigmentation, and why traditional skincare can’t keep up. We explain the science behind topical NAD+ delivery, how it compares to IVs and supplements, and why your body doesn't prioritize skin when it’s low...

Most headlines make billion-dollar beauty acquisitions sound like the ultimate win, build fast, sell big, cash out. We see it differently. In this episode, we share why we turn down investor offers and why outside funding often marks the end of real innovation.

We break down what happens when profit-first investors take over: pressure to cut ingredient quality, cheapen packaging, and churn out unnecessary products. We explain why that goes against everything we build at Young Goose, science-backed, high-integrity formulas that put skin longevity first.

We talk about the kind of growth we do want...

What if accelerated skin aging wasn’t about skincare at all, but about your metabolism?

In this episode, we’re joined by Ben Azadi, functional health coach, founder of Keto Kamp, and author of Metabolic Freedom. We unpack the link between metabolic flexibility and youthful skin, why being “stuck” as a sugar burner accelerates aging, and how insulin resistance silently damages your collagen, nitric oxide levels, and mitochondrial health, long before it shows up in labs.

You’ll also learn how skin tags reveal insulin issues, why seed oils might be worse than cigarettes, and what AGEs...

Most skincare advice treats pigmentation as a surface issue, just slap on some vitamin C and SPF, right? Not quite. In this episode, we reveal the real cellular drivers behind stubborn dark spots, melasma, and post-inflammatory pigmentation, and why conventional brightening tactics often fail long-term.

We also break down how UV, blue light, and inflammation disrupt melanocyte function and why aging skin struggles to regulate melanin evenly.

This episode gives you a layered protocol, from SPF to deeper tools like NAD+, spermidine, and more, that tackles pigment at the root. We also dive into when...

What if your face is aging faster because your bones and muscles are disappearing?

In this episode, we are joined by Dr. Vonda Wright, orthopedic surgeon and longevity expert, and we discuss how mobility, muscle, and bone density are the missing links in skin aging. We unpack why post-menopausal inflammation reshapes your face, how “Ozempic face” is really about tissue quality, and why lifting heavy weights might be the most effective anti-aging tool.

You’ll also learn why facial structure collapses with bone loss, how estrogen protects your skin via immune regulation, and why filler may ac...

Most body creams promise firmness but deliver irritation, not regeneration. That’s why in this episode, we expose the truth about popular anti-aging body ingredients like retinol, glycolic acid, and hyaluronic acid. 

You’ll learn why these actives often backfire on body skin and what it actually takes to build firmness, elasticity, and resilience from the inside out. We also break down the real biology of body skin aging, including slower cellular turnover, thicker dermis structure, and reduced sebaceous gland activity. You’ll understand why hydration and exfoliation alone aren’t enough, and how to support skin with the...

What if the most dangerous part of aesthetic medicine isn’t the treatment—but the hype around it?

In this episode, we’re joined by Sandra Silverman, author of From Bullshit to Botox, to break down what really works in anti-aging, and what can leave permanent damage. From botched fillers to early facelifts, Sandra shares her personal journey through almost every aesthetic procedure available and what she wishes she knew earlier.

We unpack why treatments like Sculptra, CoolSculpting, and Emsculpt are more marketing than medicine, how lymphatic stagnation and device stacking are aging your face faster...

What if your skincare could mimic Botox, without the toxins, and actively support your skin’s longevity?  We joined Tony Wrighton on the Biohacking News Podcast to break down how neuropeptides, NAD+ precursors, and copper peptides are shifting skincare from cosmetic to cellular.

We explored the real science behind Botox alternatives, the critical role of mitochondrial support, and why most products miss the mark when it comes to long-term skin health.

We also shared how Young Goose began—with a failed NAD+ delivery experiment that led to a breakthrough in skin biology.

➡️ If you’re re...

What if your skincare routine could do more than hydrate and smooth?

What if it could actually reprogram how your skin ages?

In this episode we break down exactly how to build a science-backed skin longevity routine—from the biology of skin aging to the ingredients and protocols that work at the cellular level. Whether you’re dealing with hyperpigmentation, acne, rosacea, or just want to slow down visible aging, this episode teaches you how to treat your skin like the intelligent, adaptable organ it is.

You’ll learn why NMN, NR, and spermi...

Think your SPF 50 is giving you extra protection? Not exactly.

In this episode of Biohacking Beauty, we’re breaking down the truth about sunscreen—because what you don’t know might be damaging your skin. From hidden ingredients that mess with your microbiome to why higher SPF might actually give you a false sense of security, this is your no-BS guide to smarter sun protection.

We also get into how filters like oxybenzone and avobenzone can impact your skin barrier, why “broad spectrum” doesn’t always mean full protection, and why texture, finish, and reapplication matter just...

What if your breakouts, fine lines, and melasma weren’t about finding the “perfect” product, but fixing what’s happening under the surface?

In this episode, we’re joined by Jamie McGuire, functional aesthetician and founder of Jamie Ann Aesthetics, to explore what truly personalized skincare looks like—and why most routines miss the mark.

We unpack how internal stress, diet, hormones, and nervous system dysfunction show up on your face, why you shouldn’t chase quick fixes, and how to build an anti-aging protocol that actually works. We also discuss the most common skincare mistakes keepi...

What if the missing key to youthful skin, pain-free movement, and true longevity wasn’t in a serum or surgery, but in your fascia?

In this episode, we’re joined by Ashley Black, fascia expert, innovator, and creator of the FasciaBlaster®, to explore why this often-ignored system may be the body’s most powerful regenerative tool.

We break down how fascia impacts skin elasticity, blood flow, and even stem cell signaling, why popular beauty devices may be doing more harm than good, and how fascia remodeling can reverse stiffness, stagnation, and aging at every level. 

We...

What if reversing joint pain, skin aging, and inflammation wasn’t about more supplements, but about better signals?

In this episode, we’re joined by Dr. Ross Carter, a regenerative medicine expert and founder of the Young For Life protocol, to explore how stem cells, exosomes, peptides, and biologics are shaping the future of aging.

We unpack the science of cell signaling, inflammation, and tissue regeneration, and why most people approach regenerative medicine all wrong. We dive into how perinatal stem cells work, the truth about exosomes and MMPs, why enzyme neutralization matters more than coll...

What if the secret to glowing skin, a sharper brain, and a revived sex drive isn’t more skincare, but hormone replacement therapy?

In this episode, we’re joined by Karen Martel, certified hormone specialist and founder of The Hormone Solution, to unpack the misunderstood science of beauty and aging. From pheromones and libido to collagen and facial structure, we explore how estrogen, progesterone, and testosterone shape how you look, and how you feel.

We break down how hormone loss affects everything from your skin’s elasticity to your body composition, and why most women are be...

What if the key to younger skin, stronger muscles, and a sharper mind isn’t more cardio—but more connection?

In this episode, we’re joined by Kristin McGee, a nationally recognized yoga and wellness educator who bridges classical practice with modern science to help people live, move, and age better, inside and out.

We unpack the science of mindful movement and its direct impact on aging. From her days on 30 Rock to launching Peloton’s yoga platform, Kristin shares what 30+ years of teaching has taught her about resilience, skin vitality, and aging well.

We div...

What if your skin issues—breakouts, dullness, inflammation—weren’t random, but deeply connected to your cycle?

In today’s episode, we are sharing a recent conversation we had on the Revital Health Podcast with Jodi Duval. We dive into something I feel incredibly passionate about: how each phase of the menstrual cycle affects our skin, and how aligning our skincare rituals with those hormonal shifts can create real, visible change.

We also talk about Anastasia’s (YG Co-founder) personal postpartum skin struggles, why traditional skincare advice often fails women, and the biohacking strategies I use to sup...

What if your skin problems aren’t skin-deep at all, but rooted in your gut?

In this episode, we’re joined by gut health expert Joni Laiho to explore one of the most overlooked yet powerful connections in skin longevity: the gut-skin axis. If you’re dealing with adult acne, stubborn inflammation, accelerated aging, or skin that just doesn’t bounce back, this conversation is for you.

We break down how gut dysfunction silently drives skin issues, the early signs your gut is leaking into your face (literally), and the doctor-backed protocols that can rebuild your ski...

In this episode, we break down some of the most viral skincare trends you see all over Instagram and TikTok, face ice baths, jelly eye patches, salmon sperm facials, red light masks, Morpheus 8, niacinamide overload, and more.

But here’s the thing: just because a trend is everywhere doesn’t mean it works, or that it supports your skin long-term.

We don’t hype or bash blindly, we give you the science-backed truth so you can make smart, informed choices about what’s actually worth your time (and money). From understanding why face ice baths aren’t t...

What if your skincare routine could actually trigger your body’s built-in anti-aging pathways? Most products just treat the surface, but aging starts much deeper, at the cellular level.

In this episode of the Biohacking Beauty Podcast, I’m talking with Dr. Melissa Cano, Director of Science at Longevity Labs and one of the smartest voices out there when it comes to spermidine, autophagy, and cellular health. Melissa has spent years teaching practitioners and biohackers how polyamines like spermidine can activate the body’s natural cleanup process, support mitochondrial health, and actually help cells function younger.

We g...

In today’s episode, Anastasia and I are diving into a topic that’s on everyone’s lips—Botox. It’s become a standard in many beauty routines, but the truth is, Botox isn’t as simple as it’s made out to be. While it can smooth out wrinkles, repeated use can actually change the way your face moves and functions, leading to long-term issues like muscle atrophy and loss of natural expression.

We’re not here to scare you, but to arm you with the knowledge you need to make informed, empowered decisions about your skin. We’re brea...

In today’s episode, Anastasia and I are tackling a topic that doesn’t get enough attention in skincare: your neck and chest. These areas age faster than your face, and most people completely overlook them in their routines. But why? The skin here is thinner, less hydrated, and more vulnerable to environmental stress. Gravity, sun damage, and even posture all contribute to crepey skin and sagging.

We’re diving into the biology of why the neck and chest age faster and what you can do about it. We’ll talk about essential strategies to keep your skin fir...

Hey everyone, welcome back to Biohacking Beauty! In today’s episode, we’re diving into red light therapy, one of the most science-backed tools for skin rejuvenation. But not all devices are created equal. I’ll break down the top five things you need to know before investing in a red light therapy device.

We’ll start with the science behind red light therapy, from wavelengths to irradiance, and how these factors impact skin health. I’ll also explain why certain devices fall short and how to identify the ones that truly deliver results. Plus, I’ll touch on the...

Hey everyone, welcome back to Biohacking Beauty! In this episode, we’re diving deep into a truth most skincare routines ignore: your environment might be aging you faster than time ever could.

We start with a story of two identical twins, same genes, same skincare habits, but drastically different aging outcomes. Why? One lived surrounded by clean nature. The other, in an urban jungle filled with air pollution, EMFs, blue light, and toxic stress. The difference wasn’t just visible, it was cellular.

In this episode, I explore how environmental stressors silently sabotage your skin by d...

Most people think menopause is just about hot flashes and mood swings—but what if I told you it’s actually one of the biggest drivers of skin aging? From collagen loss to increased sensitivity, breakouts, and inflammation, hormonal shifts can make you look older, faster. And yet, no one is talking about it.

To uncover the real impact of menopause on skin health (and what you can do about it), I’m joined by Dr. Jessica Shepherd, an OB-GYN, menopause expert, and founder of Sanctum Med & Wellness. She’s on a mission to rewrite the menopause narrativ...

Your skin is a reflection of your cellular health—but what if you could influence it on a deeper level? Red light therapy (photobiomodulation) is changing the way we think about aging, collagen production, and inflammation. In this episode of the Biohacking Beauty podcast, Amitay Eshel and  Anastasia Khodzhaeva, co-founders of Young Goose Skincare, break down how red light therapy impacts skin longevity, from boosting collagen to reducing inflammation. They explain what determines individual results, the common mistakes people make, and how to get the most out of this powerful technology.

But here’s the truth that not e...

Welcome back to Biohacking Beauty! In this episode, we tackle the controversial topic of Botox and explore effective alternatives for those seeking more natural approaches to youthful skin. Young Goose co-founder Anastasia Khodzhaeva opens up about her personal experience with Botox treatments and why they didn't work for her, while we discuss the science behind various alternatives.

Rather than demonizing Botox, we examine both sides of this polarizing beauty topic, offering insights for those who use Botox and those looking for different options. From peptides and cellular repair compounds to professional treatments and at-home techniques, we break...

Hey everyone, welcome back to Biohacking Beauty! Today, we’re exploring one of the most fundamental mechanisms of aging—telomeres. These nucleotide sequences at the ends of our chromosomes act as protective caps, preserving DNA integrity during cell division. However, each time a cell replicates, telomeres shorten, eventually leading to cellular senescence, dysfunction, or apoptosis.

In this solo episode, I’m breaking down the molecular mechanisms behind telomere shortening, how factors like oxidative stress, inflammation, and metabolic dysfunction accelerate the process, and, most importantly, what we can do to slow or even reverse this decline.

We’ll...

Today, we’re diving into a discovery that could reshape how we think about aging—C15, a newly identified essential fatty acid that plays a crucial role in cellular resilience, inflammation control, and longevity.

For decades, we’ve been told to avoid saturated fats, but what if that advice led to widespread nutritional deficiencies? Dr. Stephanie Venn-Watson, a veterinary epidemiologist and co-founder of Fatty15, uncovered C15’s role in strengthening cell membranes, reducing oxidative stress, and even influencing epigenetic aging—all from studying long-lived Navy dolphins.

In this episode, we break down how C15 protects against ce...

For years, skincare has been about quick fixes, hydration, plumping, and surface-level treatments that make your skin look better but don’t actually reverse aging. But what if the future of skincare wasn’t about temporary effects, but about reprogramming your skin at the cellular level?

In this episode of Biohacking Beauty, I take a deep dive into longevity skincare and the science behind true skin rejuvenation. We’re going beyond the outdated skincare model and breaking down the Skin Longevity Matrix, a biohacking approach designed to restore youthful function from within.

I cover...

Today, we’re diving into something that goes way beyond skincare, how your skin is actually a powerful window into your overall health and longevity. Most people think of aging as just wrinkles and fine lines, but the reality is that what’s happening on the surface is a direct reflection of what’s going on at the cellular level.

To explore this, I’m joined by Nick Engerer, a longevity scientist and the founder of A Longer Life, where he helps people take a data-driven, strategic approach to optimizing health and aging. Nick’s work is all about...

For years, skincare has focused on surface-level solutions, moisturizers, retinol, collagen creams… but what if we told you that true skin rejuvenation starts at the cellular level? Traditional skincare is designed to mask aging, but new research in longevity science reveals that the root causes of aging go much deeper.

In this episode of Biohacking Beauty, I break down the real drivers of skin aging, from mitochondrial dysfunction and NAD decline to epigenetic shifts, senescent cells, and impaired autophagy. I also discuss why most anti-aging products don’t actually reverse aging, and how cutting-edge biohacking ingredients like NAD+...