All-In with Chamath, Jason, Sacks & Friedberg

(0:00) Martin Shkreli joins the Besties!

(0:55) Why quantum computing is a one-trick business and why he's betting against it

(7:42) The drugs big pharma sells too cheap and his journey from hedge fund trader to pharma

(11:37) AI, drug discovery, and who actually wins

(21:32) Brilliance and rule-breaking, the gifted-kid trap & what prison taught him

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(0:00) Bestie intros!

(2:53) Anthropic believes Claude might be conscious: a new religion? Lobbying the Pope, alignment risks, model welfare

(38:28) OpenAI's math breakthroughs and community backlash

(1:02:03) Riots in France, Friedberg's socialism metric, bond market

(1:21:41) Grok Bot goes headless, OpenAI launches Dots, is IP worthless?

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(0:00) Bestie intros!

(2:01) Trump's Super Intelligence Summit: Behind the scenes and how the accord was created and signed

(17:57) Cybersecurity arms race, data center national security, America.gov, coordinated doomer messaging

(45:22) Recent economic data: GDP, jobs, diesel, inflation, rates, manufacturing, poverty, and more

(1:00:24) Midterm predictions, 2028 look ahead

(1:09:28) Media coverage of attempted terrorist hijacking

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(0:00) Jake Paul joins the Chamath!

(6:41) Turning an audience into businesses, the boxing playbook & coming for the UFC

(11:54) Attention as capital, investing without the celebrity label & why politics is next

(20:46) Drew Taggart & Alex Pall join the Besties!

(30:35) From artists to investors: picking deals, playing the sixth man & what fame buys

(37:33) Advice for famous investors, whether fame helps or hurts & the non-obvious bets

(46:10) Riding winners, getting cash back to investors & spotting bubble behavior

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(0:00) Daniel Ek joins the Besties!

(1:14) Starting Spotify: Beating piracy and betting his own money on the record labels

(6:10) Neko Health: The Spotify playbook for healthcare, the $499 body scan, and why US healthcare waits until you're sick

(36:04) AI: Tech's failure to sell the upside, open vs. closed models, and regulating compute

(44:24) Back to Spotify: Podcasting's open standards and the Stardoll origin story

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As wealth grows, complexity compounds. Between investments, tax strategy and estate planning, c...

(0:00) Bestie Intros: Favorite All-In Summit moments

(3:54) Reacting to AI chaos: Liability, competition, and rebranding frontier "labs"

(20:03) Open Source performance and cost: What this means for frontier companies

(29:22) Anthropic and OpenAI postpone IPOs: liquidity risk and open source pressure

(53:11) Political reactions to "Pacing the Frontier": Bernie's AI ban, Trump, Bessent, Obama

(1:07:58) Meta launches Muse, AI "alignment," Oracle's Force Majeure

(1:27:13) Anthropic's bio research and "wet lab" in SF

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(0:00) Luca Ferrari joins the Besties!

(1:56) Crashing an AI startup, the $40,000 restart & buying product market fit

(4:59) The in-house tech stack, shrinking the teams & the 10 out of 10 standard

(9:55) Debt as an accelerant, what happens if rates rise & who else is bidding

(14:58) Inside the deal desk: what gets acquired, why they don't build & the founder question

(20:22) Building a tech giant out of Milan, Europe's talent pool & the outsider advantage

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(0:00) Steve Hilton joins the Besties!

(3:53) How one-party rule broke the state, regulatory bloat & who really writes the laws

(12:09) The path to victory: the persuadable voter, the cost-of-living pitch & the case against Becerra

(21:46) Spencer Pratt joins: the message that cut through & the LA race that flipped

(26:58) The city up close: the parks, small business & who the rules actually reward

(36:54) Ballot harvesting, voter ID & whether the system is rigged or just legal

(47:13) The Palisades: the empty reservoirs, suing the state & what Spencer does next

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(0:00) Welcome Blake Scholl!

(5:11) Solving the sonic boom & legalizing supersonic flight

(7:59)  The pivot to powering data centers

(10:38) Jason joins: data center demand, private jets & what winning looks like

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(0:00) Welcome Naveen Rao

(4:45) Is energy really the problem? The cost of a token, power contracts & the gap to close

(10:24) Cutting out the middleman: abstractions, dynamical systems & a new kind of machine

(19:46) Chamath joins: the path to product, porting existing models & building the team

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(0:00) Adam Foroughi joins the Besties!

(3:07) Discovery vs search & is your phone listening?

(10:04) IPO tumble & becoming your own best investor

(16:00) Privacy rules, Apple's crackdown & how agents change people's shopping

(20:00) How a lean team beats the giants, margin moats & building in China

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(0:00) Bill Gurley takes the stage at the All-In Summit

(1:29) Bill's Presentation: Searching for Feynman

Links to additional resources mentioned in talk and used in research:
 https://www.p3.institute/searching_for_feynman_resource_links.html

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(0:00) NASA Administrator Jared Isaacman lays out the state and future of NASA

(17:59) Moon base, creating new space industries, NASA's next chapter

(23:29) How to make Mars realistic

(25:30) Recruiting, moonshots, the "Nuclear NASA," new vehicles and the importance of humans in space

(32:43) Allocating capital toward scientific discovery and deep space research

(35:46) Space Race 2.0: China and Russia

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(0:00) Nick Shirley debuts his new video: "Inside California's High Speed Rail to Nowhere"

(11:42) Nick joins The Besties to discuss California's "Stop Nick Shirley Act" and recent fraud arrests

(17:03) How he got into investigative journalism and finding fraud

(23:32) Selective journalism and why Nick is a major threat to mainstream outlets

(27:34) What's next for Nick: Investigating welfare fraud, building his platform

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(0:00) Dina Powell McCormick joins The Besties!

(1:52) Impact of Meta's data center in Richland Parish, LA: $50K teacher checks, revitalizing a small town community

(11:52) How Meta is alleviating data center concerns: pollution, electricity, water, noise, aesthetics; Misinformation campaigns

(19:57) America's Workforce Academy, the job growth in re-industrializing America

(26:58) Meta's recent social media settlement, new rules for teens

(35:25) Meta glasses and Zuck's AI strategy

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(0:00) Welcome Brad Gerstner!

(1:01) Trump Accounts, Every Child a Capitalist & The CAC Scan

(5:07) Can AI revenue pay for the CapEx?

(8:53) The Build Out Issue: Gigawatts, TAM, Token Growth, and Margin Expansion

(12:30) The risks: AI regulation, the nuclear precedent, power limits, and rising rates

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(0:00) VP JD Vance joins The Besties!

(1:40) Assessing the Trump Admin so far: Border control, re-industrialization, inflation, Iran, government debt, anti-fraud

(9:28) AI approach: Dealing with Doomerism, "Frankenstein," and AI negativity

(16:23) H-1B abuse and the massive $1T+ of fraud in federal spending

(21:48) Relationship with Israel, rational foreign policy

(25:19) JD Vance's midterms message

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(0:00) Satya Nadella joins The Besties!

(0:55) Dario's blog, "pacing the frontier," common sense AI safety

(6:28) The failure of AI CEO messaging, monitoring agents, what will a slowdown mean for new AI products?

(14:22) Economic incentives for frontier lab doomerism, where the AI profits are

(22:45) Microsoft's master plan for AI, how they are allocating capital

(31:00) China's slow down, changing AI perception, data center benefits

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(0:00) SpaceX's Gwynne Shotwell joins The Besties!

(1:45) Gwynne's SpaceX story, selling rockets, and working for Elon

(6:45) Running modern day SpaceX: AI, Starlink, Rockets, and X

(13:43) Direct to cell with Starlink, retiring rockets, competition

(18:34) Data centers in space

(22:00) Management at SpaceX

(27:37) Elon Musk joins: AI's real risk, model peer review, what he meant by "Dario is right"

(36:53) Elon and Gwynne on their working relationship, Starship's future

(46:16) Terafab, Tesla, Flying cars?, merging Tesla and SpaceX

(52:51) Lying AIs, how to do AI peer review right<...

(0:00) Jensen Huang joins The Besties!

(1:39) Thoughts on Dario's blog, Frontier Labs calling to slow down AI, and Doomer psychology

(9:58) Sensible AI regulation and RSI

(16:05) Hugging Face acquisition, future of Open Source, and the race with China

(22:58) President Trump calls in live to discuss the Doomer Hoax

(31:29) The AI boom and Nvidia's capital allocation strategy

(40:21) Nvidia's Open Source model ambitions, thoughts on Elon's Terafab

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(0:00) Bestie intros!

(0:35) AI Doomsday: Valid concern or Doomer psyop?

(33:40) Steelmanning AI Doomsday scenarios and the impact on Anthropic's IPO

(58:45) OpenAI says it cracked a 200 year old math problem, but did it front-run users with their own data?

(1:19:55) Nike removed from S&P 100 after stock tanks 80%: What went wrong?

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(0:00) Bestie intros: Happy 50th Chamath!

(1:17) OpenAI releases GPT-6 Astra: Have they reached AGI?

(19:01) All-In Summit: Scholarships available!

(19:56) Dwarkesh's Hugging Face hack article sparks a Bernie Sanders AI ban

(37:03) EAs, AI-brained influencers, and the conflicts of interest

(59:26) Mamdani bans AI in NYC schools K-8 

(1:18:58) US-Venezuela oil deal

The All-In Summit is only 1 week away! You won't want to miss it: https://theallinsummit.com

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(0:00) Bestie intros: Recapping recent interviews and the state of American science

(3:31) China's Robot Olympics, Optimus update, Grok Bot

(9:05) Nvidia and Salesforce rip after big earnings: AI Capex Bubble and SaaSpocalypse narratives get reversed

(33:32) Bessent gets called out by Druckenmiller for bond market interference

(1:01:33) AI writing controversy: Druck used AI to write his WSJ Op-ed

(1:15:00) CIA Chief visits Moscow, Meta's settlement and new teen rules

(1:22:52) Science Corner: Moderna's mRNA cancer vaccine

Come hang with the Besties at the All-In Summit | September 13-15:

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(0:00) Eric Weinstein joins the show!

(03:09) Has American science stalled? Cowboy science, Fauci, and the scientific precariat

(21:31) Weinstein's fix: Blow a hole in the Civil Rights Act, kill peer review, fund people not ideas

(41:36) Ed Witten drove physics off a cliff, and is Renaissance Technologies a secret Los Alamos?

(52:49) Boom, Vroom, Zoom: Did stagnant physics save the human species?

(01:07:11) UAPs, multi-temporal adversaries, and Einstein's prison

(01:16:12) China poaches our best scientists, AI reads the trash can corpus

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(0:00) Michael Kratsios joins the show!

(01:56) Is this administration anti-science? The Nature poll, DEI grants, and $8B down the drain 

(8:16) Climate science cuts: RCP 8.5 gets pulled and the "climate emergency" narrative collapses

(13:45) $47B at NIH, Eroom's Law, and golden tickets: has American science stagnated? 

(22:24) Big bold bets: Genesis Mission, quantum by 2028, fusion by 2035, boots on the moon in '28 

(34:04) The great race with China: $33B to $670B, and 7 out of 10 STEM PhDs aren't American 

(44:09) Fauci did more damage to science than anyone in modern history, and NIH's median rese...

(00:00) Besties are back!

(00:13) Dario's two-part essay: regulatory capture, doomerism, and the data center backlash

(10:25) FINRA for AI vs. MPAA for AI: SROs, thinking tokens, and the "DMV for AI"

(30:12) Is an open source ban coming? Harnesses, FDI, jobs, and recursive self-improvement

(56:33) a16z under DOJ investigation over "interlocking directorates"

(1:01:15) Midterms: broken polls, the socialism surge, and CATO's DSA price tag

Come hang with the Besties at the All-In Summit | September 13-15:

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(0:00) The most controversial company in privacy right now, Flock CEO joins the show!

(7:23) License plate data retention: 7 days solves 90% of crimes

(13:00) Camera vandalism, felony charges, and privacy concerns

(18:15) Dirty cops exposed: Flock's audit tool got 9 Georgia officers fired

(28:25) AI, drones, facial recognition, and avoiding predictive policing

(39:43) Safety is a privilege and who actually needs Flock

(45:36) Flock's PR crisis: internal morale, churn, and 20 cities turning the cameras back on

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(0:00) Gavin Baker joins the show!

(2:36) Anthropic IPO report: $2T valuation, $100B+ run rate, October listing

(27:32) Zuck's AI manifesto: What it means for Meta and frontier AI

(56:41) All-In Summit Speaker Announcements!

(58:13) Nvidia's $500B financing plan, how the AI market could fall apart

(1:14:29) NJ and Mamdani take on Amazon over subcontracted drivers

(1:27:32) Grok 4.6 launch: SpaceX's high-ceiling, high-floor AI strategy

(1:35:21) Workday in talks to be acquired by Silver Lake for ~$43B

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(0:00) Jason and Friedberg welcome Rahm Emanuel

(1:16) Lessons from working with Clinton and Obama

(7:45) China: How to approach conflict, new economic bloc, isolation, and Taiwan

(28:49) Europe: Reasons for the decay of the West

(38:37) Immigration: US solutions, who to emulate, subsidizing college for Americans

(46:55) National debt, government interference in markets, fixing education

(1:09:24) DSA vs Democrats

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(0:00) Bestie intros! Brad Gerstner fills in for Chamath

(2:16) Major shakeups at Google: AI brain drain or better strategy?

(20:39) SpaceX's big quarter: Terafab, AI Capex, $1T revenue projection?

(45:44) All-In Summit Speaker Announcements!

(48:01) Airtable sells for a 90% discount: SaaSpocalypse?

(1:05:56) Chinese AI labs are buying US training data to catch up

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(0:00) Saronic founders join the show!

(4:56) The Navy's first autonomous rescue in the Strait of Hormuz, and how China out builds America 230-to-1

(13:04) $3B destroyers vs. Marauder

(21:25) Killing cost-plus, the new primes, and why only 1% of the budget goes to autonomy

(25:55) Could 10,000 Corsairs actually lock down a 20-mile strait?

(31:25) China's arming robot dogs: will our AI weapons hurt us in Taiwan?

(36:33) Exclusive announcement: Port Alpha lands in Brownsville: 4000 acres, 10,000 jobs

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Creative Planning. As wealth grows, complexity...

(0:00) Bestie intros

(1:19) Chip stocks crash, Leopold Aschenbrenner's $20B fund gets margin called

(20:20) China's advantage and green shoots for the US economy

(34:12) Frontier Labs say "SLOW DOWN AI"

(1:01:15) Why are frontier labs "burning books"?

(1:14:45) Socialism Corner: Mamdani's grocery stores and the "Socialist Spectacle"

(1:24:44) Science Corner: Understanding and mapping the brain

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(0:00) Intro: Humanoids, Robots, & AI+

(0:57) ANYbotics' Dr. Péter Fankhauser: Why ANYbotics Bet the Company on Four-Legged Robot Dogs, Not Humanoids

(13:18) Dr. Péter Fankhauser: China's Armed Robot Dogs Are "Stupid and Risky" — Inside the Terminator Debate

(15:01) NEO's Bernt Børnich: Neo Ships in 2026 and Becomes an Open Robot Platform

(22:18) Bernt Børnich: Robots Building Robots in Just 3 Years — "Hard Takeoff"

(33:45) Boston Dynamics' Amanda McMaster: Spot Is Now the Most Deployed Robot on Earth — Atlas is the Most Capable

(42:36) Amanda McMaster: Chinese Robotics Security Risks

(47:14) Agility Robotics...

(0:00) Bestie intros!

(0:18) The fight to save open source AI: Kimi K3 panic, Anthropic/OpenAI regulatory capture

(27:38) Anthropic/OpenAI historic growth rates, China's long game

(48:29) Anthropic's $1.5B piracy settlement and the great IP theft hypocrisy

(1:07:12) Google and Tesla stocks tank on surging AI capex

(1:17:19) Socialism Corner: "Evictions = Violence" and the threat to private property rights

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(0:00) Bubble talk: Comparing today's AI market to the dot-com bubble

(7:50) AI's real-world limits: why enterprise AI is harder than expected

(16:38) Transitioning to an AI-First Workspace

(21:26) Health & AI: self-directed healthcare and biometric data

(24:30) Politics, wealth tax, and AI as a truth-seeking force

(35:12) Knicks & Sports Talk

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(0:00) Bestie intros!

(1:32) New AI regulatory proposal: DeepMind's Demis Hassabis proposes FINRA-type body

(20:01) Stripe, Block, and Advent offer $53B to acquire PayPal

(37:51) Apple sues OpenAI, alleging stolen trade secrets

(42:49) Grok Build data leak, AI data privacy, Tokenmaxxing update, Mira Murati's new model

(59:53) NY bans datacenters, becoming first state to enact a moratorium

(1:22:57) Science Corner: New data on reversing aging!

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(0:00) Former Intel CEO Pat Gelsinger joins Jason!

(1:41) What Went Wrong at Intel

(15:19) Why a Taiwan Blockade Would Cripple the US Economy

(25:00) Lovable's Anton Osika: One Million New Apps a Week

(33:38) How Lovable is Bringing Down Builder Costs

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PLAUD — If your work depends on conversations — meet...

(0:00) ElevenLabs' $600M ARR Ramp, 600 Employees & Life Without PMs

(15:34) Celebrity Voice Deals, Deepfake Impersonation & Racing OpenAI and Anthropic

(31:42) Legora's Hypergrowth, Disrupting Law Firms & the Billable Hour

(42:31) LexisNexis Decline, Legal Data Moats & Legora's Narrow AI Models

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Oracle powers AI at every scale—from frontier labs to enterprise production. Yo...

(0:00) Bestie intros: Brad Gerstner fills in for Friedberg!

(2:58) OpenAI vs Anthropic IPOs: Why it matters who goes first, what they learned from the SpaceX IPO, the unlimited TAM of intelligence

(27:39) The open source decision, Meta's new model, Zuck's price war, AI duopoly

(54:29) CCP considering putting export controls on Chinese models, is open source ending in China?

(1:03:09) Trump Accounts launch, getting young Americans bought back into capitalism

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(0:00) The AI Buildout: Datacenters Bigger Than Cities (Andrew Feldman)

(1:50) Reasoning, Inference, and Breaking Moore's Law

(16:28) Open Source, AI Sovereignty, and the Road to AGI

(40:54) The Innovation Behind Generative Video (Robin Rombach)

(47:31) Martin Scorsese, Robots, and the Future of Hollywood IP

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