Harrison's PodClass: Internal Medicine Cases and Board Prep

40 Episodes
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By: AccessMedicine

Produced by McGraw Hill, Harrison's Podclass delivers illuminating and engaging discussions led by Drs. Cathy Handy Marshall and Charlie Wiener of The John Hopkins School of Medicine on key topics in medicine, featuring board-style case vignettes from Harrison's Review Questions and chapters from the acclaimed Harrison's Principles of Internal Medicine – available on AccessMedicine from McGraw Hill.

Ep 185: An 89-Year-Old with Lack of Appetite and Weight Loss
#185
Yesterday at 6:00 PM

This episode discusses key concepts in the care of the geriatric patient.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 184: A 65-Year-Old with Anemia
#184
02/26/2026

This episode reviews peripheral blood smears and how they guide diagnosis.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 183: A 75-Year-Old with Acute Fever and Altered Mental Status
#183
02/19/2026

This episode discusses the symptoms and laboratory findings seen in patients with West Nile virus.

Read more on this topic in Harrison's chapters:

Encephalitis

Arthropod-Borne and Rodent-Borne Virus Infections

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 182: A 64-Year-Old with Abnormal Colonoscopy
#182
02/12/2026

This episode reviews the epidemiology and complications related to diverticular disease.


Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 181: A 64-Year-Old with Fatigue and Low-Grade Fevers
#181
02/05/2026

This episode discusses types of cardiac murmurs.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 180: A 64-Year-Old with Fever
#180
01/22/2026

This episode discusses fever of unknown origin (FUO) and unexplained inflammation.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 179: A 62-Year-Old with Fatigue
#179
01/15/2026

This episode reviews common causes of fatigue, and the additional history and physical findings needed for the next steps in evaluation.


Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 178: A 57-Year-Old with Neck Pain
#178
01/08/2026

This episode reviews the diagnostic approach to acute neck pain.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 177: A Patient with Low Blood Pressure
#177
12/18/2025

Part of our Physiology at the Bedside collection, this episode reviews the physiology of shock.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 176: A 34-Year-Old Who Skipped Medications
#176
12/11/2025

This is the next episode in our Physiology at the Bedside series and reviews complications that can arise when a patient forgets to take their medications.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 175: A 38-Year-Old with Cardiac Arrest
#175
12/04/2025

Continuing our Physiology at the Bedside series, this episode examines the potential causes of pulseless electrical activity (PEA) arrest.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 174: A 65-Year-Old Man with Dyspnea on Exertion
#174
11/28/2025

From our Physiology at the Bedside series, this episode reviews pulmonary function tests.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 173: A 48-Year-Old Woman with Heart Failure
#173
11/20/2025

In this installment of our Physiology at the Bedside series, we cover heart failure and the physiology behind its different types.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 172: A 52-Year-Old Man with an Increased Respiratory Rate
#172
11/13/2025

In this episode in our “Physiology at the Bedside” series, we discuss the causes and pathophysiology of acidosis.


Read more on this topic in Harrison's

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 171: A 19-Year-Old Woman with Lower Extremity Edema
#171
11/06/2025

The first episode in the series, “Physiology at the Bedside” discussing the mechanisms of lower extremity edema.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 170: A 35-Year-Old with Changes in Vision
#170
10/30/2025

This episode is a discussion with Harrison’s editor, Dr. Andrew Josephson, about multiple sclerosis.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 169: A 65-Year-Old with Right-Sided Weakness
#169
10/23/2025

This episode is a discussion with Harrison’s editor, Dr. Andrew Josephson, about the treatment of stroke.

Read more on this topic in Harrison's.


Harrison's Principles of Internal Medicine, 22nd Edition


Ep 168: A 52-Year-Old with Abdominal Pain and an Elevated Lipase
#168
10/16/2025

This episode discusses the causes and evaluation of pancreatitis.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 167: A 23-Year-Old with Abdominal Pain and Diarrhea
#167
10/09/2025

This episode reviews the differential diagnosis of abdominal pain in a young woman, along with the classification and treatment of the underlying condition.

Read more on this topic in Harrison.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 166: A 64-Year-Old with Fatigue, Difficulty Sleeping, and Dyspnea on Exertion
#166
10/02/2025

This episode reviews the diagnosis and acute management of tachycardia.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 165: A 63-Year-Old with an Elevated Hemoglobin
#165
09/25/2025

This episode reviews the workup and differential diagnosis of a patient with an elevated hemoglobin (polycythemia), discovered on routine labs during an evaluation for fever and diarrhea.

Read more on this topic in Harrison's chapters:

Anemia and Polycythemia

Polycythemia Vera and Other Myeloproliferative Neoplasms


Harrison's Principles of Internal Medicine, 22nd Edition


Ep 164: A 25-Year-Old Pregnant Woman Asking About Her Thyroid
#164
09/18/2025

Today’s episode discusses thyroid testing and function in pregnancy.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 163: A 39-Year-Old with a Snakebite
#163
09/11/2025

Today’s episode reviews different types of snakes and the clinical consequences of snakebites.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 162: A 73-Year-Old Woman with Fever and Altered Mental Status
#162
09/04/2025

This episode discusses a particular cause of sepsis and its treatment following a foodborne illness.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 161: A 28-Year-Old Pregnant Woman with an Abnormal Urinalysis
#161
08/28/2025

In this episode, we discuss asymptomatic bacteriuria in a pregnant woman.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 160: A 32-Year-Old Pregnant Woman Seeking Advice on Exposures
#160
08/21/2025

This episode reviews the epidemiology of lead exposure in the United States and its health implications.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 159: A 30-Year-Old at High Altitude
#159
08/14/2025

This episode discusses the diagnosis and treatment of acute mountain sickness.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 158: A 58-Year-Old with an Elevated PSA
#158
08/07/2025

This episode talks about prostate-specific antigen (PSA) screening.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 157: A 44-Year-Old with Cirrhosis and Shortness of Breath
#157
07/31/2025

This episode reviews pleural effusions and how to distinguish between their different causes.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 156: A 24-Year-Old Man with Noonan Syndrome and a Heart Murmur
#156
07/24/2025

Today’s episode discusses congenital heart disease and reviews murmurs associated with particular valvular disorders.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 155: An 18-Year-Old with Trauma to the Chest
#155
07/17/2025

In this episode, we review the differential diagnosis of cardiac injuries.

Read more on this topic in Harrison's.


Harrison's Principles of Internal Medicine, 22nd Edition


Ep 154: A 58-Year-Old Going for Surgery
#154
07/10/2025

Evaluation needed for a patient preparing for elective surgery.

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Harrison's Principles of Internal Medicine, 22nd Edition


Ep 153: A 55-Year-Old Here for an Annual Physical
#153
07/03/2025

This episode discusses prostate cancer screening and risk-reducing strategies.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 152: A 66-Year-Old with Inability to Speak
#152
06/26/2025

This episode reviews the diagnosis, etiology, and treatment of strokes and transient ischemic attacks.

22nd Edition of Harrison's – Now Available on AccessMedicine

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 151: A 55-Year-Old with Cardiac Amyloid
#151
06/19/2025

This episode reviews important concepts related to cardiac transplantation.

Read more on this topic in Harrison's.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 150: Gas Exposure
#150
06/12/2025

This episode examines toxic gas exposures—how they present, how to recognize them, and the antidotes that can save lives.

Read more on this topic on AccessMedicine.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 149: A 20-Year-Old with an Abnormal Chest X-Ray
#149
06/05/2025

Read more on this topic on AccessMedicine.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 148: A 55-Year-Old Man with Obesity
#148
05/29/2025

This episode discusses the diagnosis of obesity, associated conditions, and treatment considerations.

Read more on AccessMedicine.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 147: A 55-Year-Old with Hypertension
#147
05/22/2025

In this episode, we explore non-pharmacologic strategies for controlling blood pressure.

Read more on this topic on AccessMedicine.

Harrison's Principles of Internal Medicine, 22nd Edition


Ep 146: A 73-Year-Old Female with Lower Extremity Swelling
#146
05/15/2025

This episode covers a woman experiencing subacute edema and anasarca due to renal disease, and reviews the possible underlying causes.

Read more on this topic on AccessMedicine.

Harrison's Principles of Internal Medicine, 22nd Edition