Sit. Stay. Learn. with Dr. Adrienne Wright
Regenerative medicine is one of the fastest growing fields with new papers published every single day. As a busy mom of two, I am guilty of not making the time to keep up with the research, and I think a lot of other veterinary professionals are in the same situation.My name is Dr. Adrienne Wright and I am the site leader and VP of science at Ardent Animal Health. Life can get busy and heavy, and after a long hard day, you probably aren’t choosing to unwind with 16 pages of dense, scientific data. Really, who is? That’s why...
5. UC-MSCs After Trochlear Groove Reconstruction in Dogs

This week on Sit. Stay. Learn., I reviewed a 2022 study by He et al. in Frontiers in Veterinary Science that tested whether umbilical cord-derived mesenchymal stem cells (UC-MSCs) could improve recovery after trochlear groove reconstruction (TGR) in dogs. Ten healthy poodles were divided into treatment and control groups, with UC-MSCs injected intra-articularly on days 0, 7, and 14. The treated dogs showed significantly lower white blood cell and neutrophil counts on days 7 and 21, indicating less inflammation, and recovered mobility about four days faster than controls. CT and histology revealed early cartilage regeneration and restored bone contour in the UC-MSC group, while controls...
4. Adipose-Derived MSCs for Chronic Kidney Disease

Today’s Paper: Adipose-Derived MSCs for Chronic Kidney Disease
This week, I’m switching gears. Most of the studies I cover are animal-focused, but this time we’re looking at a human pilot study that gives us insights we can bring right back into veterinary medicine.
Paper: “Adipose tissue-derived mesenchymal stromal cells for treating chronic kidney disease: A pilot study assessing safety and clinical feasibility.”
Authors: Villanueva, González, Lorca, Tapia, López G, Strodthoff, Fajre, Carreño, Valjalo, Vergara, Lecanda, Bartolucci, Figueroa, Khoury. Journal/Year: Kidney Research and Clinical Practice, 2019.
Why This Matt...
3. PRP for Prostatic Cysts

This week, I reviewed a case study sent to me by our own technical services veterinarian, Dr. Larry Snyder. If you’ve never had the chance to talk with Dr. Snyder, you should—he’s got over 20 years of regenerative medicine experience and a passion for helping vets think through tough cases.
The paper itself looked at platelet-rich plasma (PRP) for the treatment of prostatic cysts in dogs. It comes from researchers in Italy and was published in The Canadian Journal of Veterinary Research in 2018
2. MSC Therapy for Feline Asthma

For today's episode, I wanted to focus on Cats, who are often overlooked in veterinary research. MSCs offer a new approach to feline asthma. They’re immunomodulatory, capable of balancing immune responses and promoting regulatory pathways that could help manage chronic airway inflammation.
1. Does PRP have anti-microbial properties?

For our first episode, I wanted to look at platelet-rich plasma (PRP). Two veterinarians recently emailed me asking whether PRP has antimicrobial properties. Honestly, I’d never really considered it before—but if it does, that would be another big advantage on top of its known uses for joint injections. It might also explain why we rarely see complications after intra-articular PRP use.