Well Beyond 40

Some of your organs could be aging faster than the rest of your body

Today I’m with functional medicine expert, bestselling author, and repeat guest Dr. Will Cole to explore why your cells may be aging faster than your chronological age suggests. We unpack the everyday factors that can create cellular confusion, from metabolic dysfunction and environmental toxins to disrupted light exposure, chronic stress, and the foods you eat, then explore practical ways to rebuild resilience through nutrition, fasting, nature, sleep, and targeted therapies. Most importantly, I want you to come away knowing that yo...

I’m breaking down why keeping weight off can be much harder than losing it in the first place and what happens to your metabolism, hunger hormones, and body composition after weight loss. I’ll walk you through the habits that successful weight-loss maintainers consistently use, from resistance training and daily movement to protein, fiber, self-monitoring, sleep, and stress management. Most importantly, I’ll show you why lasting results require more than maintaining a number on the scale: they require becoming the person who naturally lives the habits that support a healthy, lean body.

What you’ll learn...

The key to preventing Alzheimer’s begins DECADES before you notice memory problems. 

I’m joined by my longtime friend Dr. David Perlmutter, a board-certified neurologist and bestselling author who has spent decades challenging conventional thinking about brain health. We explore why Alzheimer’s may be less about removing beta amyloid and more about protecting the brain’s immune system through exercise, metabolic health, nutrition, muscle, social connection, and a healthier environment. Most importantly, I want you to walk away knowing that your brain’s future is not something you simply have to accept because your daily...

The first few minutes of your morning can shape your focus and mood for the entire day.

I sat down with brain coach and bestselling author Jim Kwik to explore what it really takes to keep your brain strong, focused, and adaptable as you age. We talk about why your brain needs regular challenges just like your muscles do, how your morning inputs can shape the rest of your day, and why outsourcing too much thinking to AI could work against your cognitive health. Most importantly, we break down simple daily choices you can use...

The scale is measuring the WRONG thing about how well you’re aging.

I want you to stop looking at the scale as the ultimate measure of how well you're aging and start paying attention to the performance markers that reveal what your body can actually do. In this episode, I break down why grip strength, VO2 max, muscle quality, and mitochondrial health can tell you so much about your future strength, energy, resilience, and independence. I'll also show you how resistance training, protein, recovery, and targeted muscle support can work together to help you bu...

FULL EPISODE HERE: https://youtu.be/x_hEHVpFy5k?si=tTZzlQg3F2IsBYdW 

I’m diving into vitamin C with Dan Pardi, who brings a research-focused perspective to what may be one of the most underestimated nutrients in healthy aging. We explore how absorption changes as you get older, why form and timing matter, and what vitamin C may have to do with exercise adaptation, cellular senescence, brain health, and biological aging. I also get into the practical questions you’re probably asking, including how much to take, when to take it, and how vitamin C mig...

Did you know you can misuse your GLP-1? 

I’m with health optimization pioneer and bestselling author Dr. Jay Campbell to unpack what people are getting right and wrong about GLP-1s and peptides. We explore why these therapies can be about much more than weight loss, including their potential roles in metabolic health, muscle preservation, mitochondrial function, energy, and longevity. Most importantly, we talk about why these powerful tools still need to sit on top of the fundamentals, including protein, resistance training, healthy hormones, quality sleep, and smart metabolic habits.

What...

Which healthy aging fundamentals matter more than the latest wellness hacks?

I’m busting some of the biggest health myths women hear in midlife, from fasting and dairy to hormone replacement, protein, keto, collagen, and muscle building. I’ll show you why your best strategy after 40 isn’t chasing every new wellness trend but getting the fundamentals of protein, resistance training, blood sugar, sleep, stress, gut health, and hormones dialed in. My goal is to help you cut through the conflicting advice, understand what the science actually says, and make choices that help you feel strong, energi...

FULL EPISODE: https://youtu.be/iG9M8DPyoOw?si=IDhlyMYrq4ECsszN 

Dr. Kiran Sachdev speaks the language of the gut, including the less glamorous details most people avoid discussing. Her approach helps patients improve digestion, rebuild their microbiomes, and understand how gut health can influence everything from brain fog to bone health.

In this episode, she uncovers how aging can change your stomach acid, digestion, motility, and microbiome. We explore why eating more protein is not enough if you cannot properly break it down, and why pairing protein with fiber and p...

What if your autoimmune symptoms are evidence that your body is responding intelligently rather than attacking itself?

Today, I’m sitting down with functional medicine practitioner and autoimmune expert Dr. Greg Mongeon to challenge the idea that autoimmune disease means your body has simply turned against itself. We explore how chronic infections, toxic exposure, stress, liver and gut function, thyroid conversion, and nervous-system dysregulation can influence both autoimmunity and the hormonal changes of perimenopause. You’ll learn why testing must be paired with a meaningful conversation and how simple foundational habits can help remove the inte...

"Doctors are humans, and we are patients, too. I decided to start sharing what I was doing in my own life, and it has transformed the way I practice medicine, the way I parent, and literally every aspect of my life." - Dr. Jamie Seeman

I had to track down Dr. Jamie Seeman (a.k.a. Dr. Fit and Fabulous) because her content is absolutely amazing! As a board-certified OBGYN with specialized training in nutrition, menopause, and exercise science, Jamie brings a unique perspective to women's health that's both scientifically sound and personally tested. After...

Watch the full episode: https://youtu.be/6Sb22mW_24s?si=nMQtTBID6kid2pUf

Could your low-carb diet be raising your blood sugar instead of lowering it?

I’m joined by Zane Griggs, health practitioner and fitness coach, to explore why strict low-carb routines can unexpectedly backfire on your metabolism. We break down the surprising role of glucagon, an overlooked stress hormone that elevates fasting blood sugar when you chronically over-exercise or under-fuel. Listen in as we share why stepping away from rigid diet dogma and embracing smart, whole-food carbohydrates can help you re...

Which foundational health habits should you address before trying another supplement?

Today I’m with nutritional therapist and self-described “Healing Cave Lady” Mary Darnall to explore the health crisis that transformed her into a determined researcher and practitioner. We discuss why true healing often begins with simple foundations like calming your nervous system, chewing your food, hydrating with minerals, improving lymphatic flow, and reducing toxic exposures. You’ll learn why symptoms are important messages from your body and how returning to the basics can help you build greater resilience at any age.

What y...

Do you know the critical difference between pinchable subcutaneous fat and dangerous visceral adipose tissue? 

I’m breaking down why belly fat becomes such a common frustration after 40 and why it is not simply a matter of willpower. I explain how menopause, insulin resistance, stress, sleep, thyroid function, muscle loss, and food choices can influence where your body stores fat. Most importantly, I share practical ways to reduce visceral fat, preserve muscle, and work strategically with your changing biology.

What you’ll learn:

(02:36) Discover the crucial difference between subcutaneous fat an...

Did you know that testosterone is actually the most abundant sex hormone in women's bodies prior to menopause? 

I’m sitting down with Dr. Kelly Casperson, a board-certified urologist and women’s sexual health expert, to tackle one of the most misunderstood hormones in women: testosterone. We explore why testosterone matters for everything from your cellular energy and gym gains to motivation, mood, and libido, plus why a “normal” lab result might not tell the whole story. I also ask the practical questions you need answered about testing, finding the right level for your body, recognizi...

Are you mistaking temporary pain relief for actual healing?

In this episode, I sit down with my own doctor, Dr. Ashu Goyle, a double board-certified anesthesiologist and interventional pain specialist who left the world of traditional pain management to practice regenerative medicine. We dig into why cortisone shots, ablations, and even spinal fusions often accelerate the very joint and spine damage they're meant to fix, and why pain itself is a signal your body wants you to listen to, not silence. Dr. Goyle breaks down PRP, prolotherapy, and stem cell therapies so you understand exactly...

Are you carrying around a grocery bag full of daily supplements without actually knowing if they’re working for your body?

In this episode, I break down exactly which supplements matter for women over 40, from the foundational must-haves like vitamin D, magnesium, omega-3s, and creatine to the amino acids, electrolytes, and collagen I layer on top to support muscle, energy, and recovery. I answer your biggest supplement questions live, covering everything from creatine safety around kidney stones and cancer survivorship to magnesium types, taurine, B12, and what to do about a bloated belly. My goal is...

What would change about your healthcare if an AI could model your exact biology instead of general population averages?
I sat down with Dr. Darshan Shah, a physician of 30 years and the founder of Next Health, to talk about where personalized medicine is headed — starting with the wild idea of a "digital twin" that can help predict how your body will respond to everything from sauna sessions to surgery. We got into why AI is only half the equation, and why the best care will always pair that technology with an empathetic human practitioner. Darshan also walked me th...

Are you taking the right form of vitamin C, or is most of it going to waste?

In this episode, I sit down again with Dr. Dan Pardi to unpack a brand-new study revealing "ferroaging" — a mechanism where iron builds up in our tissues and quietly accelerates how we age. Dan, a researcher and health-behavior expert who helps develop products at Qualia, walks me through why vitamin C turned out to be the single most powerful compound for slowing and even reversing this process. We get into the forms, doses, and timing that actually make vi...

Did you know that women naturally have 70% to 80% lower tissue stores of creatine than men?

Creatine has evolved from a “bodybuilding” supplement into a practical tool for energy, recovery, strength, and even brain support, with especially compelling benefits for women who may have lower creatine stores and notice more fatigue, brain fog, or slower recovery. It works by helping replenish ATP, the body’s quick-access energy supply, which can translate into harder workouts, better performance, stronger muscles, and longer-term support for bone and metabolic health; while creatine monohydrate is the most studied form, many people also look a...

Why do some people look amazing after procedures while others look strange, swollen and are frankly regretful? 

In this episode, I’m sitting down again with Dr. Rady Rahban, a Beverly Hills board-certified plastic and reconstructive surgeon, to get brutally honest about what women need to know before plastic surgery. We talk about the procedures that can look beautiful when done well, the ones that are overdone or misunderstood, and the red flags that should make you walk away from a surgeon. My goal is to help you feel informed, empowered, and clear-eyed so you can...

Could your bloating, burping, or reflux actually be a sign of low stomach acid?

In this empowering episode, I sit down with Dr. Kiran Sachdev, a prominent integrative gastroenterologist and microbiome longevity specialist, to uncover how your digestive system serves as ground zero for overall wellness and powerful aging. We dive deep into the specific biological shifts that occur during menopause, including the common loss of stomach acid and the development of a leaky gut barrier, while outlining tactical solutions to slow down and reverse this decline. From customizing your individual protein-to-fiber ratio to exploiting the...

Are you tired of letting minor daily inconveniences trigger an oversized, reactive emotional response that drains your daily energy?

In this episode, I catch up with my long-time friend Dave Asprey to dive deep into the science behind his groundbreaking book, Heavily Meditated. We break down why traditional meditation practices can fall short for modern brains and introduce a highly efficient "Reset Process" designed to erase emotional triggers and past trauma forever. By learning how to optimize your physical energy and master your biological operating system, you can stop reacting from a place of fear and...

How can you distinguish between a plastic surgeon's actual skill and a clever marketing campaign?

I’m joined by Dr. Rady Rahban for a very real conversation about celebrity plastic surgery, facelifts, fillers, and the beauty expectations women are navigating after 40. We talk about why even famous people with unlimited resources can end up with disappointing results, and why edited photos and dramatic “reveals” can create unrealistic expectations for the rest of us. Dr. Rahban also explains what actually starts changing in the face around midlife, how fillers became so overused, and what you need t...

Are you unknowingly masking chronic physical burnout under the guise of disciplined biohacking?

I invited Zane Griggs on the show to talk about the sneaky ways high performers can turn discipline into burnout, especially after 40. Zane brings such a grounded perspective on carbs, fasting, testosterone, recovery, and the lab markers that can reveal when your body is stressed instead of thriving. In this episode, we’re cutting through the noise so you can build a strong, sustainable health plan that still leaves room for joy, connection, and real life.

What yo...

What if your insomnia, migraines, or digestive issues are signs of deeper imbalance?

In this fascinating episode, I sit down with award-winning retired neurologist and Ayurvedic coach Dr. Trupti Gokani to explore how blending ancient wisdom with conventional medicine can revolutionize your well-being. We break down her unique Three Brain Optimization Program, focusing on how aligning your central nervous system, enteric nervous system, and gut microbiome addresses the true root causes of stress, insomnia, and chronic pain. By discovering your specific energetic type—whether it's vata, pitta, or kapha—you will walk away with prac...

I’m talking with Suzanne Gilberg Lenz about how women can use botanicals, hormones, and smarter lifestyle strategies to navigate perimenopause and menopause with more support. Suzanne brings her experience as a physician and menopause expert to explain which herbs may help with sleep, mood, blood sugar, hot flashes, and nervous system regulation. We also dig into why symptoms like severe hot flashes should not be brushed off, and why the right support can make a real difference for your health now and in the years ahead.

(00:11) Why combining conventional medicine like hormone replacement th...

Why are so many women still being told testosterone is only a male hormone?

I’m bringing back board-certified urologic surgeon and sex educator Dr. Kelly Casperson to unpack what women really need to know about testosterone, DHEA, vaginal estrogen, and sexual health after 40. We talk about why testosterone is not just a male hormone, how it can affect energy, motivation, libido, mood, muscle, and brain health, and why “normal” labs are not always the same as feeling your best. This conversation is about helping you understand your body, advocate for better care, and stop a...

I’m answering your biggest nutrition questions live, from how to hit your protein goals without overcomplicating your life to what you need to know about creatine, fiber, carbs, GLP-1s, and gut health. I’ll show you how to build meals that support your metabolism, protect your muscle, stabilize blood sugar, and help you age powerfully without obsessing over perfection. My goal is to help you make consistent B-plus choices that give your body the right inputs so you can look, feel, and perform your best.

What you’ll learn:

01:37 How to submit...

I’m joined by Will Harlow to talk about one of the biggest myths in aging: that getting older automatically means getting weaker, stiffer, and less capable. In this episode, we unpack why so many “age-related” issues are really signs of deconditioning, and how simple, specific strength work can help you stay mobile, independent, and strong after 50. I also loved digging into the practical tests that matter, like grip strength, chair stands, and walking speed, because muscle really does change everything.

(00:00) The biggest myth about aging after 50 is that decline is inevitable and outside of you...

How can you use AI to better understand your labs without replacing your doctor?

I’m talking with Dr. Darshan Shah about one of the most exciting shifts happening in health: the intersection of AI, personalized medicine, and longevity. Dr. Shah is a physician, founder of Next Health, and the author of the upcoming book Your New Health OS, and he breaks down how women can start using labs, wearables, and AI in a smarter, safer way. We also dig into why muscle, hormones, HRV, morning routines, and the basics of lifestyle medicine still ma...

Could GLP-1 weight loss be costing you muscle instead of just fat?

GLP-1 medications can be powerful tools, but they are not a free pass to simply eat less and hope for the best. In this episode, I’m showing you why protein, resistance training, recovery, and targeted muscle support are essential if you want to lose fat while protecting your metabolism. My goal is to help you use these tools the right way, so the weight you lose is actually the weight you want to lose.

What you’ll lear...

I’m joined by Doug Lucas for a rapid-fire myth-busting conversation about what women need to know about bone health, osteoporosis, fracture risk, and aging powerfully. Doug explains why calcium alone is not the answer, why walking is not enough to rebuild bone, and why a normal DEXA scan does not always mean you are safe. Most importantly, we talk about why bone loss is not something you simply have to accept and how the right lifestyle strategy can help you protect your strength, independence, and longevity.

(00:00) Why calcium alone may not prevent fractures an...

Why do some people look amazing after procedures while others look strange, swollen and are frankly regretful?

In this episode, I’m sitting down again with Dr. Rady Rahban, a Beverly Hills board-certified plastic and reconstructive surgeon, to get brutally honest about what women need to know before plastic surgery. We talk about the procedures that can look beautiful when done well, the ones that are overdone or misunderstood, and the red flags that should make you walk away from a surgeon. My goal is to help you feel informed, empowered, and clear-eyed so yo...

I'm exposing the truth about how high-protein foods can mimic the appetite-suppressing effects of weight loss drugs but with benefits instead of side effects. When you use Ozempic or similar medications, up to 40% of your weight loss can come from muscle, devastating your metabolism and setting you up for rebound fat gain. Protein, however, works naturally with your body's hunger hormones—slashing ghrelin for 3+ hours, maintaining healthy leptin levels, and boosting PYY—all while providing essential amino acids for mood-regulating neurotransmitters.

I'm sharing my complete Ozempic-mimicking protein protocol, including the magic combination with fiber that...

Could your “normal” labs be missing the real reason you feel exhausted, foggy, or stuck?

I’m joined by Dr. Amie Hornaman, known as The Thyroid Fixer, to talk about why so many women over 40 are told their labs are normal while still feeling tired, foggy, inflamed, and unable to lose weight. We dig into thyropause, Hashimoto’s, reverse T3, thyroid medication, and the exact labs women should ask for if they want real answers. My hope is that this episode helps you stop blaming yourself and start testing, advocating, and getting the support your bod...

What makes someone a good candidate for a facelift after 40?

On this episode of Well Beyond 40, I sit down with renowned board-certified plastic surgeon Dr. Rady Rahban to pull back the curtain on the real truths, myths, and marketing traps surrounding aesthetic procedures. We dive deep into my personal journey with my recent facelift, explore why filler over-use can backfire, and examine why younger, healthier individuals are often the best candidates for natural surgical outcomes. Whether you are trying to navigate the confusing differences between a cosmetic and plastic surgeon or determining the right...

This week, we’re revisiting one of my favorite episodes: Strong Arms After 40: Science-Backed Muscle Building.

In this behind-the-scenes episode, I'm pulling back the curtain on exactly how I've maintained strong, defined arms well into my 50s, and more importantly, why this matters so much more than just appearance. After decades in the fitness industry, I've learned that most women are approaching arm training completely wrong – focusing on light weights and endless cardio instead of the proven strategies that actually work.

I'm sharing the exact training principles I use and...

What if walking is one of the most powerful prescriptions your doctor is not writing?

I’m joined by foot and gait expert Dr. Courtney Conley to talk about why walking may be one of the most underrated tools for healthy aging. We break down the step count sweet spot, why post-meal walks matter, when to add intensity with speed or weighted vests, and why gait speed can reveal more than you might think. We also get into the overlooked connection between aging, menopause, foot strength, balance, and fall prevention so you can stay st...

Could optimizing your testosterone levels as a woman be the missing piece to improving your sleep, mood, and libido?

In this episode, I’m joined by OB-GYN, integrative women’s health expert, and author Dr. Suzanne Gilberg Lenz for a powerful conversation about botanicals, hormones, and the menopause symptoms women should stop ignoring. We talk about how herbs like ashwagandha, rhodiola, black cohosh, Siberian rhubarb, saffron, and passion flower may support sleep, mood, hot flashes, blood sugar, and nervous system regulation. Most importantly, we dig into why symptoms like severe hot flashes, night sweats, and...