The Rx Chronicles

5 Episodes
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By: Radin Alikhani

For years, we’ve heard the stories of famous artists, politicians, and scientists; even criminals—but what about the overlooked inventors whose discoveries saved lives and eased suffering? "The Rx Chronicles" takes you on a journey through the lives of the inventors behind marketed medicines, exploring who they were, what fueled their passion, and how their work has shaped the modern pharmaceutical market—all shared in a simple, relatable, and captivating language.Join me in honoring the unsung heroes of pharmacy and exploring the remarkable stories behind the medicines that shape our world.

Episode 03: Insulin's Birth - Banting & Best
#3
Today at 7:30 AM

From a bitter Nobel Prize dispute to the fragile partnerships that nearly unraveled it all, this is the untold human drama behind insulin. A story marked by clashing egos, secret experiments, and credit denied, the path to this life-saving breakthrough was anything but straightforward.

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References:

The Discovery and Early Development of Insulin - University of Toronto LibrariesThe discovery of insulin: a story of monstrous egos and toxic rivalries. By Kersten HallFrederick Banting, Charles Best, James Collip, and John Macleod - The archive of Science History Institute (Museum and Library)

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Episode 03: Insulin's Birth - Banting & Best
#3
Today at 2:10 AM

From a bitter Nobel Prize dispute to the fragile partnerships that nearly unraveled it all, this is the untold human drama behind insulin. A story marked by clashing egos, secret experiments, and credit denied, the path to this life-saving breakthrough was anything but straightforward.

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References:

The Discovery and Early Development of Insulin - University of Toronto LibrariesThe discovery of insulin: a story of monstrous egos and toxic rivalries. By Kersten HallFrederick Banting, Charles Best, James Collip, and John Macleod - The archive of Science History Institute (Museum and Library)

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Episode 02: The Water Pill Revolution - Karl Beyer Jr
#2
05/03/2025

Before the applause, there was resistance. Before the prize, uncertainty. Four names. One forgotten moment. A quiet revolution in medicine that changed the course of cardiovascular care—forever. This episode begins with a voice from 1975 and unfolds into something much bigger...

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References:

National Academy of Sciences. Biographical Memoirs: By Garabed Eknoyan. Washington, DC: The National Academies Press.Beyer KH Jr (1977). Discovery of the thiazides: where biology and chemistry meet. Perspectives in biology and medicine, 20(3), 410–420. https://doi.org/10.1353/pbm.1977.0048Drugs.com - Hydrochrolothiazide Patient Tips

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Music: Sourced from Pixabay and Udio...


Episode 01: The Mood Metal - John Cade
#1
03/21/2025

Lithium was once just a remedy for gout and bladder stones—until a psychiatrist’s bizarre experiment changed everything. After World War II, John Cade injected urine from mentally ill patients into guinea pigs, hoping to uncover the biological roots of mental illness...

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References:

Cade J. F. (1999). John Frederick Joseph Cade: family memories on the occasion of the 50th anniversary of his discovery of the use of lithium in mania. 1949. The Australian and New Zealand journal of psychiatry, 33(5), . https://doi.org/10.1080/j.1440-1614.1999.00624.xShorter E. (2009). The history of lithium therapy. Bipolar disorders, 11 Suppl 2(Supp...


Episode 0: The Backstory
03/15/2025

For years, we’ve heard the stories of famous artists, politicians, and scientists; even criminals—but what about the overlooked inventors whose discoveries saved lives and eased suffering?

In this introductory episode, I outline the vision, mission, and objectives that will guide the direction of this podcast.

Produced by: Radin Alikhani

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Instagram: @rxchronicles_

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Special thanks to the University of Michigan's Shapiro Library for providing the recording space for this episode.