APS Publications Podcast

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, Prof. S. Mehran Hosseini discusses the study, “Misconception about the application of Dalton’s Law in respiratory physiology.”

Dalton’s Law may provide a good example for students to highlight the existence of misconceptions and their effect on gaining new knowledge. The awareness of students about this misconception may improve their learning styles.

Misconception about the application of Dalton’s Law in respiratory physiology

S. Mehran Hosseini

Advances in Physiology Education 2025 49:3, 646-650

In this special episode of the APS Publications Podcast, the founding of Physiological Genomics is discussed in a series of interviews with Drs. Allen W. Cowley, Jr., Bina Joe, and Hilary Coller. These interviews were organized and conducted in September 2025 by Oluwatosin Mautin Akinola (PhD candidate in Molecular Medicine at the University of Toledo, Toledo, OH, United States; https://www.researchgate.net/profile/Oluwatosin-Akinola-2). Full videos of these interviews are available as Supplemental Material in the article.

Joe B, Cowley AW, Garrett MR, Kriegel AJ, Prokop JW, Lee EC, Akinola OM, Coller HA. Connecting Genes to Physiology: T...

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, Dr. Raju Suresh Kumar discusses a novel, hands-on simulation designed to teach auditory physiology. By experiencing unilateral conductive hearing loss, students gain deeper insight into auditory masking and sound lateralization. This simple, cost-effective method enhances conceptual understanding and clinical skills, offering strong potential for integration into medical education.

Enhancing auditory physiology: simulating unilateral conduction defects to improve understanding of Rinne’s and Weber’s tests

Raju Suresh Kumar, M. Ganesh Kamath, Rekha Prabhu, and Mohamed Eldigire Ahmed

Advances in Physiology Educati...

In this podcast, coauthors Liz Simon, Flavia Souza-Smith, Megan Donovan, Eden Gallegos, Kaitlin Couvillon, and Patricia Molina summarize their recently published review article, "Physiological Mechanisms Vulnerable to Alcohol-Induced Alterations: Role in Chronic Comorbidities." The article describes alcohol's multi-systemic physiological effects on the gastrointestinal, cardiovascular, and immune systems, as well as on energy metabolism that contribute to multiorgan injury and disease burden.

Physiological Mechanisms Vulnerable to Alcohol-Induced Alterations: Role in Chronic Comorbidities

Liz Simon, Kaitlin E. Couvillion, Meagan E. Donovan, Eden M. Gallegos, Flavia M. Souza-Smith, Patricia E. Molina

Comprehensive Physiology 2025 15:5, e70057 

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In this podcast, coauthors Simon D. Pouwels and Brady Rae discuss their recently published research article, "Interorgan Communication Between Lung and Colorectal Epithelial Cells Studied Using a Novel Multi-Organ-On-Chip System." The article describes development of a novel unidirectional millifluidic multi-organ-on-chip device to study the communication between human lung epithelial cells and colorectal cells following a toxic stimulus. Authors additionally discuss the versatility of the device to study communication across other cell types.  

Interorgan Communication Between Lung and Colorectal Epithelial Cells Studied Using a Novel Multi-Organ-On-Chip System

Brady Rae, Verena Bood, Hye-Jin Dijk, Gwenda F. Vas...

In this episode of the APS Publications Podcast, featuring an article from AJP–Regulatory, Integrative and Comparative Physiology, author Periklis Marnas discusses inhalation exposure of adult D. melanogaster to cigarette smoke and changes in physiological parameters and the expression of COPD-associated orthologous genes. The study found that transcriptomic responses were more profound in females, indicating sex-specific responses to inhaled toxicants. Furthermore, enrichment analyses of the differentially expressed genes in females pointed to biomolecules associated with response to nicotine and detoxification. D. melanogaster thus provides a powerful model system to test the efficacy of new potential drugs for COPD treatment.

...

In this episode of the APS Publications Podcast, featuring an article from AJP–Regulatory, Integrative and Comparative Physiology, authors Ziba Taherzadeh and Claire Kissell discuss the influence of race and sex and Cardiac autonomic function. Their study found that non-Hispanic Black adults living in the United States are more likely to develop cardiovascular disease compared with their non-Hispanic White adult counterparts. These results support that reduced cardiac autonomic function does not manifest early in life among young non-Hispanic Black adults, but rather non-Hispanic Black men had greater spontaneous cardiac baroreflex sensitivity and heart rate variability compared with non-Hispanic White me...

In this episode of the APS Publications Podcast, featuring an article from AJP–Regulatory, Integrative and Comparative Physiology, authors Andrea Zsombok, Lucie Desmoulins, and Adrien Molinas discuss the role of estradiol treatment in regulating metabolism and glucose homeostasis. In their study with middle-aged, high-fat diet-fed, ovariectomized female mice, the authors found that liver-related neurons in the hypothalamus became more excitable. Estradiol treatment reduced this excitability, suggesting that midlife estradiol therapy may support healthier brain-liver metabolic regulation.

Molinas AJR, Desmoulins LD, Dugas CM, Williams GL, Kamenetsky S, Felintro de Souza V, Maroteaux MJ, Davis RK, Daniel JM...

In this episode of The APS Publications Podcast, coauthors Matthew A. Hadiono, Alexis B. Kazen, Fatima A. Aboulalazm, and John R. Kirby discuss their recent study, "Reutericyclin mitigates risperidone-induced suppression of anaerobic energy expenditure," published in AJP–Regulatory, Integrative and Comparative Physiology.

The authors explore how the gut microbiome, a thermogenic biomass, plays a critical role in regulating energy expenditure. Their study shows that the composition of the microbial community, influenced by both xenobiotics and bacterial metabolites, can impact metabolic function. They found that treatment with reutericyclin counteracts the suppression of anaerobic energy expenditure caused by risperidone. Th...

In this episode of The APS Publications Podcast, coauthors John J. Durocher and Ezra Mutai discuss the Editorial Focus titled "Sleep tight with vitamin D’s might" published in AJP–Regulatory, Integrative and Comparative Physiology. The conversation centers on a recent study by Culver et al., which examines the relationship between vitamin D levels and reduced sleep variability.

Tune in to hear how these findings shed light on the potential link between vitamin D status and consistent sleep patterns.

American Journal of...

In this episode of The APS Publications Podcast, coauthors Alexander A. Buelow and J. Mikhail Kellawan discuss their recent study, "Inhibition of CYP450 pathways reduces functional sympatholysis in healthy young adults," published in AJP–Regulatory, Integrative and Comparative Physiology.

They explore how functional sympatholysis, which has traditionally been considered independent of nitric oxide and prostaglandins, may actually involve endothelial CYP450 pathways. Their findings show that inhibition of CYP450-2C9 reduces sympatholytic responses during dynamic handgrip exercise combined with lower body negative pressure. This suggests that CYP450 plays an important role in regulating blood flow during exercise in...

In this podcast, coauthors Emma Elizabeth Sabu Kattuman, Lakshminarayan Reddy Teegala, Somayeh Darzi, Charles K Thodeti, and Sailaja Paruchuri talk about their recently published review, "Leukotrienes: bridging the inflammatory gap in asthma and inflammatory bowel diseases (IBD)." The review highlights how altered leukotriene biosynthesis and signaling contribute to the pathogenesis of both asthma and IBD, and considers the therapeutic implications of targeting leukotriene pathways for patients with concurrent asthma and IBD.

Leukotrienes: Bridging the Inflammatory Gap in Asthma and Inflammatory Bowel Diseases (IBD)
Emma Elizabeth Sabu Kattuman, Lakshminarayan Reddy Teegala, Somayeh Darzi, Charles K T...

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, join coauthors Maurizio Costabile and Layla Mahdi as they discuss their study, “Leveraging computer-based simulations and immersive software technologies for enhanced student learning in laboratory medicine.” They share how these digital tools were integrated across a 4-year laboratory medicine degree and how they significantly improved student engagement and understanding. Tune in to hear how this innovative approach can be applied beyond laboratory medicine to benefit a wide range of disciplines.

Leveraging computer-based simulations and immersive software technologies for enhanced student learning in laboratory medicine

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, join coauthors Helena Carvalho and Patricia Halpin as they discuss DramaZoom is a teaching tool paired with a pretest to activate memory. It promotes learning for both medical students and undergraduate students with different majors in the study cohort. DramaZoom creates an opportunity for a fun learning experience that promotes knowledge gain in physiology regardless of whether the teaching setting is face to face or completely virtual. Future research will be done to investigate the long-term retention of content.

Introducing and validating D...

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, coauthor Katelyn Cooper highlights the meeting reports titled “Meeting report: an interdisciplinary approach to addressing anxiety in undergraduate active learning biology courses.” She explains that anxiety is a common emotional condition marked by feelings of tension, worry, and physical symptoms like restlessness and fatigue.  Among college students, anxiety is the most reported mental health concern and is linked to lower motivation, engagement, and academic performance. Biology students may be particularly affected due to the rigor and competitiveness of their courses, with high anxiety levels contributing to reduc...

In this episode of The APS Publications Podcast, corresponding author Han-Kyul Kim provides an overview of the study titled "Exercise pressor reflex function is augmented in rats with chronic kidney disease," recently published in AJP–Regulatory, Integrative and Comparative Physiology. Dr. Kim discusses how the research team uncovered exaggerated blood pressure responses triggered by the exercise pressor reflex (EPR) in a chronic kidney disease (CKD) animal model. The study highlights how both the muscle mechanoreflex, activated through passive stretch and the muscle metaboreflex, stimulated by intra-arterial capsaicin, contribute to this hypertensive effect. Tune in to learn more about how sympat...

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, coauthors Jynx Pigart, Tasneem Mohammed, and Katelyn Cooper discuss their study, “Premed pressure: examining whether premed students experience more academic stress compared to non-premeds.” Their research investigates the common perception that premedical students experience higher levels of academic stress than their non-premed peers. The findings revealed no statistically significant differences in reported academic stress between the two groups. However, the study did show that students with lower GPAs were significantly more likely to leave the premed track than those with higher GPAs.

Preme...

In this episode of The APS Publications Podcast, we hear from coauthor Casey G. Turner about the study, "Oral contraceptive pill phase alters mechanisms contributing to cutaneous microvascular function in response to local heating." Published in AJP–Regulatory, Integrative and Comparative Physiology, this study investigates the effect of OCP phase on in vivo microvascular endothelium-dependent vasodilation and explores underlying mechanisms. Present findings suggest OCP phase does not affect overall microvascular endothelium-dependent dilation but does affect the underlying mechanisms. In women using OCP, there is a robust reliance on EDHF pathways and the COX pathway moderates basal microvascular blood flow and dem...

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education. The authors present their study on the Indonesian Medical Physiology Olympiad (IMPhO). This article outlines key strategies for building a successful team in a physiology competition, including effective use of resources, mentorship, teamwork, and faculty guidance. These approaches not only enhance performance in competitive settings but can also be adapted to strengthen study techniques for medical students.

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, we hear from Dr. Himel Mondal about his recently published paper entitled “Evolving resource use for self-directed learning in physiology among first-year medical students in a classroom setting.” This study reports a shift in educational resource use for self-directed learning (SDL) among medical students after introduction of large language model (LLM) chatbots. Students use multiple sources, with digital tools like search engines and LLM chatbots nearly matching each other as the most preferred resources. Despite the accessibility and efficiency of digital tools, traditional resources like textbooks rema...

In this episode of the APS Publications Podcast, featuring Physiological Genomics, join coauthors Ibra Fancher and Malak Alradi as they discuss, “A long-term high-fat diet induces differential gene expression changes in spatially distinct adipose tissue of male mice.” This study explores how a long-term high fat diet affects gene expression in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) in male mice.

A long-term high fat diet induces differential gene expression changes in spatially distinct adipose tissue of male mice.
Malak Alradi, Hassan Askari, Mark Shaw, Jaysheel D. Bhavsar, Brewster F. Kingham, Shawn W. Po...

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education coauthor Patricia Halpin highlights the article titled "Students bypass the syllabus to utilize alternate LMS locations for assignment deadlines." Dr. Halpin highlights how the growing use of learning management systems (LMSs) has changed how students access course information—often leading them to overlook the syllabus entirely. This shift can result in confusion and missed deadlines due to reliance on inconsistent LMS postings. Tune in as she explores why it’s more important than ever for faculty to reintroduce the syllabus on day one and clearly communicate wher...

In this episode of The APS Publications podcast featuring Comprehensive Physiology, we hear from Dr. Lance Fortnow (Illinois Institute of Technology) about his recent Review exploring how artificial intelligence (AI) can play a role in digital twinning of interorgan communication. The human body is an extremely complex system with constant interorgan communication, and AI has been proven effective at modeling complex systems and understanding communication. A digital twin is a complete simulation of a physical process, providing a unique opportunity to simulate real-world physiology and pathophysiological conditions such as aging and various disease states. What role might digital twinning...

In this episode of the APS Publications Podcast, we’re joined by coauthors Chasity Corbin, Chowdhury Ibtida Tahmin, and Ida T. Fonkoue to discuss their research titled "Estradiol levels are differentially associated with pulse wave velocity in trauma-exposed premenopausal women with and without PTSD." The study investigates how serum estradiol (E2) levels influence pulse wave velocity (PWV) in premenopausal women exposed to trauma, with a particular focus on the impact of posttraumatic stress disorder (PTSD). The researchers discovered that E2 levels predicted PWV only in women without PTSD, even after accounting for factors like menstrual cycle phase, age, body ma...

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education coauthors  Baylee A. Edwards and Sara E. Brownell discuss their educational research titled "Students respond positively to an instructor collecting and sharing aggregated class demographic data from a survey in a high-enrollment physiology course." This study delves into undergraduate students' perceptions of a high-enrollment physiology course instructor gathering and sharing aggregated demographic data to foster inclusivity. Most students responded positively to this approach, with particular benefits noted by women, nonbinary students, and liberal-leaning students. Edwards and Brownell's findings suggest that collecting and sharing student demographic data i...

In this episode of The APS Publications Podcast, featuring AJP-Regulatory, Integrative and Comparative Physiology, coauthors Xiaoyu Su and Nanduri R. Prabhakar dive into their recently published research titled "Adrenal Epinephrine Facilitates Erythropoietin Gene Activation by Hypoxia Through β2 Adrenergic Receptor Interaction with Hif-2α." The study explores the role of sympathetic nervous system (SNS) activation in erythropoietin (EPO) gene expression during hypobaric hypoxia, shedding light on how adrenal epinephrine, via β2 adrenergic receptors, interacts with the transcription factor HIF-2α to enhance EPO gene activation. Tune in as they highlight the breakthrough findings that deepen our understanding of the physiological mechanisms underlying hypoxia-induced gene...

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education coauthors Nicholas Fimognari, Leaf R. Kardol, and Caitlin S. Wyrwoll discuss their published paper, “Inclusion of Genital, Sexual, and Gender Diversity in Human Reproductive Teaching: Impact on Student Experience and Recommendations for Tertiary Educators.”

The coauthors outline key teaching innovations aimed at improving inclusivity in reproductive biology and physiology education. By enhancing representation of genital, sexual, and gender diversity in the curriculum, these advancements play a crucial role in shaping the perspectives of future medical professionals and researchers. Tune in as the coauthors explore how...

Glucagon-like peptide-1 (GLP-1), a hormone released from enteroendocrine cells in the distal small and large intestines in response to nutrients and other stimuli, not only controls eating and insulin release, but is also involved in drinking control as well as renal and cardiovascular functions. This review from Comprehensive Physiology details GLP-1's roles in these interconnected systems, highlighting recent findings and unresolved issues, and integrating them to discuss the physiological and pathological relevance of endogenous GLP-1 in coordinating these functions. 

Glucagon-Like Peptide-1 Links Ingestion, Homeostasis, and the Heart.

Jean-Philippe Krieger, Derek Daniels, Shin Lee, Svetlana M...

In this episode of The APS Publications Podcast, featuring AJP-Regulatory, Integrative and Comparative Physiology, join coauthors Austin Robinson and Meral Culver as they delve into their recently published research titled "Do Not Sleep on Vitamin D: Vitamin D is Associated with Sleep Variability in Apparently Healthy Adults." The study explores the intriguing connection between vitamin D levels and sleep health, revealing that individuals with lower circulating vitamin D concentrations experience greater sleep variability compared to those with higher levels. Tune in to learn about the growing body of evidence suggesting an important link between vitamin D status and sleep...

In this episode of The APS Publications Podcast, join Tasneem F. Mohammed, Nolina Doud, Sara E. Brownell, and Katelyn M. Cooper as they discuss their recently published paper, "The Upside to Depression: Undergraduates Benefit from an Instructor Revealing Depression in a Large-Enrollment Physiology Course." In the study, an instructor of a large physiology course openly disclosed her depression to students on two separate occasions. The research explores how this revelation impacted students' perceptions of the instructor, the classroom environment, and their overall experience.

Through a survey of 289 undergraduates, the study found that most students remembered the disclosure...

In this episode, authors Dax Ovid, Ashley Rose Acosta-Parra, Arsema Alemayehu, Jacob Francisco Gomez, Dathan Tran, and Brie Tripp dive into their recently published research titled “All of us are capable, and all of us can be scientists.” They explore the profound impact of Scientist Spotlight assignments on undergraduate students in physiology courses at an emerging Hispanic-serving institution. These assignments, which highlight counterstereotypical scientists, have been shown to significantly enhance students’ feelings of inclusion and foster a deeper connection to the material. Through engaging conversations, the authors discuss how these initiatives not only change students' perceptions of scientists but also i...

In this episode, coauthors Daniela G. L. Terson de Paleville and Staci W. Saner explore their paper on incorporating Team-Based Learning (TBL) into physiology and biomedical sciences education. While TBL has become a popular method for teaching conceptual and procedural subjects, it remains underutilized in these fields. Daniela and Staci provide a step-by-step guide for integrating TBL into physiology courses and introduce their innovative Diamond Framework for TBL. Inspired by Bloom’s taxonomy, this visual taxonomy places "application" at the core, offering a new way to structure learning. Tune in to discover how TBL can transform physiology education and en...

In this episode, coauthors Eann Malabanan, Owen P. McGuinness, and Kendra H. Oliver dive into their recently published paper, "Leveraging Digital Assets: Lessons from a 14-Year-Old Isotope Tracer Course for Professional Scientists." They explore how the COVID-19 pandemic reshaped scientific training programs, forcing many to pivot to virtual formats due to social distancing and travel restrictions. With a focus on the Isotope Tracers in Metabolic Research course—a long-running training program for scientists—they discuss how the integration of digital assets not only helped maintain engagement during the pandemic but also enhanced post-pandemic in-person training. By reviewing survey data from b...

Join coauthors E.S. Louise Faber, Kay Colthorpe, Louise Ainscough, and Judit Kibedi in this APS Publications podcast as they delve into their recent paper, "Students’ Approaches to Developing Scientific Communication Skills." In this episode, they explore the strategies and resources that undergraduate science students employ to enhance their science communication abilities. Discover how different approaches can influence academic performance in written assessments and the critical role of explicit guidance and engagement with teaching staff in fostering these essential skills. Tune in for a deep dive into the intersection of education, communication, and scientific literacy, and learn how these fi...

In this episode of the APS Publications podcast, coauthor Ole J. Kemi dives into the recently published article "Graduate prospects explain undergraduate program standing in university league sports science tables." The discussion highlights how university rankings play a crucial role for applicants and stakeholders in evaluating undergraduate programs.

Kemi explains that these rankings assess various criteria affecting student life and future prospects, but the study reveals that graduate prospects—the professional benefits students gain post-graduation—are the most significant factor influencing ranking outcomes. This insight emphasizes the importance of career outcomes in shaping perceptions of program quality and...

In this episode of The APS Publications podcast, coauthor Emmanuel Bourdon highlights the illuminations article titled "Enhancing the understanding of abstract neurophysiology concepts by first-year students at the University of La Réunion." First-year physiology students can find the subject challenging, struggling to understand abstract concepts without any context. To address this, the authors introduced a pedagogical intervention for first-year medical and health physiology students that aimed to link abstract concepts and a pathological disorder, together with a discussion of a specific therapeutic intervention. This pedagogical intervention was well received by first-year physiology students who better understood how basic n...

In the latest APS Publications Podcast, coauthors Karyn Robichaud, and Brynne Duffy discuss their fascinating research on the altered mitochondrial microRNA profiles in thirteen-lined ground squirrels during hibernation. This study sheds light on the metabolic changes these squirrels undergo during torpor and IBE, revealing 38 liver mitomiRs that differ based on hibernation state.

Physiological Genomics 2024 56:8, 555-566

In this episode of The APS Publications podcast, coauthors Shea E. Carr, Thad E. Wilson, and Jennifer L. Osterhage highlight their education research titled "Assigned group work is associated with increased student motivation and perceptions of belonging in an asynchronous online physiology laboratory course." This study explores the effect of assigned group work in an asynchronous online physiology laboratory course on student motivation and belonging. Students’ perceptions of belonging and competence-related beliefs were higher, and effort and psychological costs were lower, when assigned to groups compared to students not assigned to groups. Students assigned to groups noted peer interactions as...

In this episode of The APS Publications Podcast, Brian D. Ott highlights the recently published paper titled "Hypothalamic transcriptome response to simulated diel earthen pond hypoxia cycles in channel catfish (Ictalurus punctatus)." Channel catfish are an economically important species that experience diel episodic periods of hypoxia that can reduce appetite. This is the first study to investigate their transcriptome from the hypothalamus in a simulated 24-h span in a commercial catfish pond, with 12 h of hypoxia and 12 h of normoxia. The research revealed functional groups of genes relating to hypoxia, angiogenesis, and glycolysis as well as individual target genes...

Listen to the latest APS Publications Podcast as Seán Roe, Mary K. McGahon, Sharon Parkinson, Etain Tansey, and Paul Murphy discuss an innovative approach to medical education encouraging drama students to take on the role of simulated patients. A cross-disciplinary learning experience not to be missed! This podcast and paper detail how physiology tutorials for early years medical students are transformed by taking the clinical case off the two-dimensional page and instead having the case scenario acted by drama students. This adds context and authenticity. The benefits are twofold: emphasizing the importance of physiology to the budding clinician a...