Dishing The Science with Dr. Sue

Can semaglutide (Wegovy), tirzepatide (Mounjaro/Zepbound), or liraglutide (Saxenda) benefit liver health - and what did we recommend in our new 2025 Obesity Canada Pharmacotherapy Clinical Practice Guidelines? Find out here!

Learn more: https://drsue.ca/2025/08/do-glp1-based-weight-management-medications-benefit-liver-health/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own...

Some people on weight management medication may want to stop treatment because of cost, or perhaps because they want to again try 'doing it on their own'. What do our new Obesity Canada 2025 Clinical Practice Guidelines recommend on this topic?

Learn more: https://drsue.ca/2025/08/what-happens-if-you-stop-weight-management-medication-and-what-do-our-new-obesity-canada-guidelines-advise/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult...

In our NEW 2025 Obesity Canada Pharmacotherapy Clinical Practice Guidelines, we identified many existing gaps where data is lacking. Where did our Guidelines leave us wanting for more? Where is more research needed? Find out here!

Learn more: https://drsue.ca/2025/08/obesity-canada-2025-pharmacotherapy-guidelines-what-couldnt-we-answer/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for...

As the lead author, I am thrilled to ANNOUNCE publication of our long-awaited 2025 Obesity Canada Clinical Practice Guidelines!  Includes 13 recommendations, a brand new Decision Tool&Table to guide in the choice of medication, Key Messages for Health Care Professionals and Key Messages for People With Obesity. ENJOY!! 

Learn more: https://drsue.ca/2025/08/obesity-canada-pharmacotherapy-clinical-practice-guidelines-2025-published/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If yo...

Erectile dysfunction (ED) is common in men with elevated weight. Can weight loss medications improve ED?

Learn more: https://drsue.ca/2025/08/can-weight-loss-medications-improve-erectile-dysfunction-ed/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation. Postings on this podcast represent the personal opinions of Dr. Sue Pedersen. They are...

In choosing the best GLP1-based medication for our patients with type 2 diabetes at high risk of cardiovascular disease, guidelines recommend choosing one that has proven reduction in risk of CV events in cardiovascular outcome trials (CVOTs). High level results just released on Mounjaro's SURPASS CVOT study tell us how mounjaro stacks up. Read on to find out!

Learn more: https://drsue.ca/2025/08/how-does-mounjaro-stack-up-for-cardiovascular-protection-the-surpass-cvot-results/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical...

Can creatine supplements preserve muscle during weight loss? 

Learn more: https://drsue.ca/2025/07/can-creatine-supplements-preserve-muscle-during-weight-loss/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation. Postings on this podcast represent the personal opinions of Dr. Sue Pedersen. They are not representative of, nor endorsed by, Alberta Health S...

We often talk about sleep as a luxury in our busy lives. But what if we redefined sleep entirely? What if we thought of sleep like an essential vitamin – non-negotiable, restorative, and vital? It’s time we start seeing sleep as a nutrient.

Learn more: https://drsue.ca/2025/07/sleep-is-a-nutrient/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you...

As we gain 20+ years of experience with GLP1-based treatment, I continue to be fascinated by the diversity of potential benefits that we are finding in clinical trials and in clinical practice.  A fascinating article was recently published reviewing the potential benefits of GLP1-based medication to skin conditions. Find out more here!

Learn more: https://drsue.ca/2025/07/could-glp1-weight-loss-diabetes-medications-benefit-skin-conditions-like-psoriasis-or-hidradenitis-suppurativa/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor t...

Could the next generation of weight management medications include treatments given just once a month? Find out more here!

Learn more: https://drsue.ca/2025/06/will-once-a-month-weight-loss-medication-be-the-next-big-step-forward/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation. Postings on this podcast represent the personal opinions of Dr. Sue...

I was honored to present results of CagriSema - Wegovy+Amylin (cagrilintide) - as an up-and-coming weight managment medication at the American Diabetes Association meeting yesterday, with simultaneous publication of our results in the New England Journal of Medicine.  Find out more here!

Learn more: https://drsue.ca/2025/06/wegovy-plus-amylin-cagrisema-weight-management-results-revealed/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem y...

Diabetes is a risk factor for cardiovascular (CV) disease.  But could the risk of heart attack and stroke be elevated, even DECADES before the diagnosis of type 2 diabetes is made? Find out more here!

Learn more: https://drsue.ca/2025/06/could-risk-of-heart-attack-and-stroke-risk-rise-decades-before-type-2-diabetes-diagnosis/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice s...

Could GLP1 and glucagon work together to provide weight loss benefits and improvement to metabolic and liver health? Find out about the results of the first phase 3 study of a dual GLP1/glucagon receptor agonist (mazdutide) here! 

Learn more: https://drsue.ca/2025/06/mazdutide-first-phase-3-glp1-glucagon-dual-agonist-weight-management-results/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your o...

When we as doctors think about risks of any medication, the first thing that comes to mind is the potential for side effects. But when I ask my patients what they perceive as potential risks of treatment, often the answer is something else entirely.  What does a recent publication tells us about what is on people's minds? 

Learn more: https://drsue.ca/2025/05/what-do-people-list-as-top-3-risks-of-weight-management-medication-and-none-of-them-are-side-effects/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical ad...

Tirzepatide, which has been approved in Canada as a diabetes medication (Mounjaro) since 2022, received Health Canada approval for weight management this week (called Zepbound).  What do you need to know?

Learn more: https://drsue.ca/2025/05/zepbound-mounjaro-tirzepatide-for-weight-management-approved-in-canada/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation. P...

Zepbound/Mounjaro and Wegovy face off in a head-to-head trial.  How did they compare? 

Learn more: https://drsue.ca/2025/05/zepbound-mounjaro-and-wegovy-face-off/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation. Postings on this podcast represent the personal opinions of Dr. Sue Pedersen. They are not representative of...

For a person living with obesity who has had already had a hip or knee replaced, can weight loss with obesity medication reduce the risk of needing a revisional surgery?

Learn more: https://drsue.ca/2025/04/can-weight-loss-with-obesity-medication-reduce-risk-for-revisional-surgery-after-hip-or-knee-replacement/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation...

With the significant reduction in food intake that highly efficacious weight management medications can induce, it's important to consider whether a person is getting adequate nutritional and nutrient intake with treatment.  Today I ask the question: Should we be routinely recommending vitamins with weight loss medication?

Learn more: https://drsue.ca/2025/04/should-vitamins-be-prescribed-with-weight-mangement-medication/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a...

While heart attack and stroke risk are top of mind for clinicians, peripheral artery disease is often overlooked. What are the symptoms, how is it diagnosed, and what can we do about it?

Learn more: https://drsue.ca/2025/04/the-hidden-disease-peripheral-artery-disease-and-what-we-can-do-about-it/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to...

We know that several INJECTABLE GLP1 receptor agonists reduce cardiovascular events in people with type 2 diabetes. Now published is the first study ever to show that a GLP1 in a PILL can reduce cardiovascular events as well. Read on to learn more!

Learn more: https://drsue.ca/2025/04/first-glp1-in-a-pill-to-reduce-cardiovascular-events-in-people-with-type-2-diabetes/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical...

Could (an often secret) feeling of shame and blame be a reason why some people say no to weight loss medication?

Learn more: https://drsue.ca/2025/04/could-shame-and-blame-be-a-reason-why-some-people-say-no-to-weight-loss-medication/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation. Postings on this podcast represent the personal opinions of...

While we know that hormones and genetics play a big role in the physiology of hunger, there are around a trillion other reasons that are getting more credit for their contributions - learn about these microcritters here!

Learn more: https://drsue.ca/2025/03/could-the-bacteria-in-your-gut-be-driving-weight-gain/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician...

When taking weight management medication, it's important not to overlook the impact this can have on other medications taken for other health concerns. What are some of the medications that we need to think about?

Learn more: https://drsue.ca/2025/03/when-you-take-weight-loss-medication-which-other-medications-may-need-adjusting/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice...

Some men with elevated weight struggle with infertility. Given the weight and metabolic benefits of GLP1 receptor agonists, could GLP1 based weight management medications like liraglutide (Saxenda), semaglutide (Wegovy), or tirzepatide (Mounjaro/Zepbound)  improve male reproductive health?

Learn more: https://drsue.ca/2025/03/could-glp1-based-weight-management-medications-help-sperm-quality/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own p...

Are there any special considerations for use of weight loss medications in older people? Find out here!

Learn more: https://drsue.ca/2025/03/can-older-people-take-weight-loss-medication/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation. Postings on this podcast represent the personal opinions of Dr. Sue Pedersen. They...

In a recent podcast, I dished on how the menopausal transition can lead to weight gain.  What can we do to manage weight successfully during this challenging time?  Listen on to find out!

Learn more: https://drsue.ca/2025/02/perimenopause-what-are-the-keys-to-successful-weight-management/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to yo...

Does ozempic curb alcohol consumption?  Find out about the results of the first trial to answer this question!

Learn more: https://drsue.ca/2025/02/does-ozempic-curb-drinking/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation. Postings on this podcast represent the personal opinions of Dr. Sue Pedersen. T...

A particularly challenging time for weight management for many women is the menopausal transition – which, by the way, can last up to 10 years. Why is it so hard to manage weight during this time? Find out here!

Learn more: https://drsue.ca/2025/02/how-does-the-menopausal-transition-impact-weight-management/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician fo...

Diabetic retinopathy (DR) is a common complication of diabetes, affecting the eyes and potentially leading to vision loss. But did you know it might also be linked to insomnia? Find out more here!

Learn more: https://drsue.ca/2025/02/can-diabetic-retinopathy-eye-complications-lead-to-sleepless-nights/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to...

Much controversy exists as to whether, when, in whom, or for how long GLP1 based medications should be held prior to receiving anesthesia or sedation for surgery or procedures like colonoscopy. Check out this new guidance just published - find out what is new and different from prior guidance in 2024.

Learn more: https://drsue.ca/2025/01/do-glp1-based-weight-management-diabetes-medications-need-to-be-held-before-anesthesia-or-sedation-updated-guidance/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health...

The Lancet commission suggests a new definition of obesity, clinical obesity and preclinical obesity.  Is this a step forward or step back?

Learn more: https://drsue.ca/2025/01/the-lancet-commission-on-the-diagnosis-of-obesity-a-step-forward-or-a-step-back/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation. Postings on this podcast represent the personal opinions o...

Weight gain is a known side effect of many antipsychotic medications. A new guideline published in Schizophrenia Bulletin provides important updates on this topic.

Learn more: https://drsue.ca/2025/01/new-guideline-on-metformin-for-prevention-of-antipsychotic-medication-induced-weight-gain/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation. Postings on this podcast represent the...

We know that we lose fat and muscle when we lose weight. What happens to bone when we lose weight? Does it matter what treatment strategy you use to lose weight? And, does any change in bone with weight loss translate to an increase in fracture risk?

Learn more: https://drsue.ca/2025/01/how-does-weight-loss-affect-bone-health/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you...

It is often assumed that people with obesity should have stronger bones as they are supporting a higher weight, and thus be at a lower risk of broken bones (fracture). Is this really true?

Learn more: https://drsue.ca/2024/12/how-does-obesity-affect-bone-health-and-fracture-risk/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific...

A high level press release of the SURMOUNT-5 study shows that more weight loss is seen with Mounjaro/Zepbound than Wegovy. But does this mean that Mounjaro/Zepbound is BETTER?

Learn more: https://drsue.ca/2024/12/mounjaro-zepbound-and-wegovy-face-off-is-one-better-than-the-other/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation...

Yesterday, Health Canada approved semaglutide 2.4mg (Wegovy) to reduce the risk of heart attacks in people with cardiovascular disease and overweight or obesity.  This is a landmark moment in Canada. What does it mean for people with overweight or obesity and cardiovascular disease? Find out Dr. Sue's thoughts here!

Learn more: https://drsue.ca/2024/11/health-canada-approves-wegovy-to-reduce-risk-of-heart-attacks/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to t...

What's new in the Diabetes Canada 2024 guideline on how to choose the best medication for diabetes?

Learn more: https://drsue.ca/2024/11/diabetes-canada-2024-pharmacotherapy-guidelines-update-whats-new/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation. Postings on this podcast represent the personal opinions of Dr. Sue Pedersen. They...

Can tirzepatide (Mounjaro/Zepbound) provide long term weight loss, prevent diabetes, and treat heart failure with preserved ejection fraction? It's been a busy week - find out here!

Learn more: https://drsue.ca/2024/11/3-year-sustained-weight-loss-powerful-prevention-of-diabetes-and-heart-failure-benefit-with-tirzepatide-mounjaro-zepbound/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you have a medical problem you should consult your own physician for advice specific to your own situation. Postings on...

Knowing what to do to prepare a person using GLP1 based medication for surgeries requiring anesthesia or sedation remains a clinical conundrum. New multisociety clinical practice guidance was just published in an attempt to harmonize recommendations. What does this updated guidance tell us we should do?

Learn more: https://drsue.ca/2024/11/new-guidance-on-what-to-do-with-glp1-medications-before-surgery-or-sedation-whats-clear-and-whats-not/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care providers. If you...

Obesity-related knee osteoarthritis is caused not only by increased weight stress on the joints, but also by the chronic inflammatory state that is seen in obesity. Can weight management medication reduce pain?  Find out about the results of a study of Wegovy in people with obesity and knee osteoarthritis here!

Learn more: https://drsue.ca/2024/11/knee-pain-from-osteoarthritis-can-weight-management-medication-help/

Any medical discussion on this podcast is intended to be of a general nature only, and is intended for a Canadian audience. This podcast is not designed to give specific medical advice to patients, nor to their health care p...