Addiction-Rx

Join your co-hosts, Dr. Narasimha and Dr. Aishwariya, as they explore the essentials of uncomplicated alcohol withdrawal. Alcohol withdrawal is a common presentation across medical settings, and early recognition is key. In this episode, we outline the clinical features, assessment, and evidence-based management approaches that help prevent complications and support sustained abstinence. Whether you're a trainee or a practising clinician, this concise discussion offers practical guidance for everyday clinical care.

This episode is not a substitute for clinical judgement. Listeners are encouraged to refer to standard textbooks and guidelines for comprehensive clinical decision-making.

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Brief Intervention

Disulfiram is the first drug that was approved for alcohol use disorder by the FDA in 1948 .

Disulfiram is a white odorless and tasteless powder and is soluble in water and alcohol. This is the reason many times surreptitiously family members give it but usually end up causing more harm than good.

Mechanism of action of disulfiram-It irreversibly inhibits acetaldehyde dehydrogenase enzyme which is required for conversion of acetaldehyde to the acetate.

Acetaldehyde get accumulated into the body and is responsible for an unpleasant reaction and this is called as the disulfiram ethanol reaction...

Diagnosis and management alcohol related withdrawal seizure by Dr Gaurav Singh

Why, when, and how long to use a Nicotine patch

What is Thiamine? Why do we need to supplement patients with AUD and How much?.

Why do some get addicted and why others do not. Let us listen to Prof Vivek Benegal, Professor, Centre for Addiction Medicine, NIMAHNS

Investigation in a patient with Alcohol Dependence

Choosing of anti-craving agent for ADS

Choosing anti-craving in patients with alcoholic liver disease

In this episode, the discussion is focused on long-term pharmacological management of AUD in ALD. Here, we discuss all the available options for management of AUD and tease out as to which one would suit for patients for ALD discussing their metabolism

Physicians are likely to encounter alcohol withdrawal syndrome in their patients with Alcohol Use Disorders. Most patients with early stage of liver disease are likely to manifest milder withdrawal symptoms. But patients with significant liver disease are likely to present with moderate to severe withdrawal symptoms. The AWS can range from insomnia, tremor, autonomic hyperactivity to more severe seizures and delirium tremens. The symptoms usually start from 6 to 8 hrs of last drink and pick in 24-72 hours. Oxazepam and Lorazepam are preferable for AWS patients with ALD. For patient with severe ALD like cirrhosis or encephalopathy, benzodiazepine should be...