Boundless Life

Full show notes: BenGreenfieldLife.com/507

In this episode, you’ll discover how much protein to eat in a calorie deficit to hold on to muscle, which bodybuilding myths you can drop, and what can help tighten loose skin after GLP-1 weight loss. I walk you through a new meta-analysis of 29 studies on dieting lifters, why I set my own target higher at 1 to 1.5 grams per pound, and whether switching up exercises builds bigger arms. You’ll also learn how close to failure you really need to train, why fasted cardio may not burn more fat, and why skin...

Full show notes: BenGreenfieldLife.com/spysecrets

In this episode, I’m re-airing my conversation with former covert CIA officer Andrew Bustamante, founder of EverydaySpy. My friend Adam Wenguer introduced us by saying Andrew was great at marriage, homeschooling, and biohacking, and that he used to be a spy. You’ll hear what a polygraph really measures, how the CIA rebuilds officers after an operation, and the recovery tools he leans on, including L-theanine, CBD oil (use code BEN15 for 15% off), and watered-down electrolyte drinks (get a free sample pack with any drink mix order).

Andrew walk...

Full show notes: BenGreenfieldLife.com/healthyheart

In this episode, I’m re-airing my conversation with biochemist and engineer Patrick Theut about how he cleared the plaque from his own heart. Patrick was 48, winning 5Ks and playing ice hockey when he passed every test in a Mayo Clinic physical, then asked for one more scan they said he didn’t need. It came back with his left main artery lit up, and a cardiologist gave him four years to live. I went through something very similar myself, which is why this one stuck with me.

You’ll hea...

Full show notes: BenGreenfieldLife.com/thymuspodcast

In this episode, I sit down with internal medicine physician Dr. Abud Bakri to talk about the thymus, the small gland on top of your heart that trains your immune system and starts shrinking as soon as you hit puberty. You’ll hear what speeds that shrinkage up, from birth control and testosterone therapy to chronic infections, stress and a leaky gut, why Korean eunuchs lived longer, and which blood markers, like the ratio of helper to killer T cells (CD4-to-CD8 ratio), give you a window into how your thymus is...

Full show notes: BenGreenfieldLife.com/lowcarbhighcarb

In this episode, I'm re-airing the first debate ever held on the Boundless Life podcast, with repeat guest Jay Feldman and Duke obesity medicine physician Dr. Eric Westman going head to head on whether your cells run better on carbohydrates or fat. The carbs-are-good, carbs-are-bad argument has only gotten louder, and this is still the best version of it I've heard.

You'll hear Jay's case that burning fat creates more oxidative stress and drives up stress hormones like glucagon and cortisol over time, and Eric's case from decades of...

Full show notes: BenGreenfieldLife.com/thyroidhealth

In this episode, I'm re-airing one of the most comprehensive thyroid conversations I've ever had, with repeat guest Dr. Amie Hornaman. Six doctors told her she was normal while she gained 25 pounds in contest prep, and the seventh finally found the goiter.

You'll hear why thyroid stimulating hormone (TSH) on its own misses most of the picture, how reverse T3 can block your active thyroid hormone at the cell door, and why only 2% of hypothyroid patients do well on T4 alone. We get into T2, the thyroid hormone almost...

Full show notes: BenGreenfieldLife.com/ultimatelongevity

In this episode, I'm pulling the best of three longevity conversations into a best-of compilation: blood oxygen as the root of nearly every disease pathway, the molecule that clears out your worn-out mitochondria, and a 61-year-old engineer who is out-aging tech billionaires on a normal budget. All three come at the same problem from completely different directions.

First, Gary Brecka on what two decades of predicting death for life insurance companies revealed, why he says the presence of oxygen is the absence of disease, and the magnetism, oxygen and...

Full show notes: BenGreenfieldLife.com/drtyna

I'm re-airing my conversation with Dr. Tyna Moore about GLP-1s because almost everything she said about them is still being misunderstood, and she was one of the earliest voices advocating for using these drugs at very low doses. When we recorded, the internet had largely decided GLP-1 agonists were terrible: muscle wasting, "Ozempic face," suicidality, and more. Tyna's take was very different, and much of what she discussed has held up surprisingly well. Not everything, though. The big Alzheimer's trials found that GLP-1 treatment did not significantly slow disease progression.<...

Full show notes: BenGreenfieldLife.com/AGIpodcast

In this episode, you'll hear how artificial intelligence is actually being pointed at aging right now, including an algorithm picking which Chinese herbs extend a fruit fly's life, plus whether the biological age test you just paid for means anything at all.

My guest is Dr. Ben Goertzel, who popularized the term artificial general intelligence, runs a decentralized AI network, and is chief scientist at Hanson Robotics. We get into the long-lived fruit flies his team works on at Genescient, the roughly five traditional Chinese herbs an AI selected...

Full show notes: BenGreenfieldLife.com/506

In this episode, you'll discover three things I've been asked about constantly: whether the melatonin heart failure headline is worth worrying about, how much sleep is actually too much or too little, and the shortest route to a higher VO2 max.

I break down what the melatonin study did and did not reveal, why a key prescription detail changes how the findings should be interpreted, and why I still use high-dose melatonin for jet lag. Then I move to VO2 max, including the Norwegian 4x4 explained the way I used...

Full show notes: BenGreenfieldLife.com/gutsolution

In this episode, you'll meet Josh Dech, a former paramedic turned Crohn's and colitis consultant who argues that all three things Western medicine says about inflammatory bowel disease are wrong: it's not genetic, not classically autoimmune, and not idiopathic. We walk the research trail from a 1988 Swedish twin study through the NOD2 gene to the genome-wide studies that mapped hundreds of risk loci and still explained only a sliver of the disease, and into the numbers that worry him most, where the West has 6% of the world's population but 60% of its...

Full show notes: BenGreenfieldLife.com/limitlessdaily

In this episode, you'll hear repeat guest Jim Kwik talk about cognitive offloading and where the line sits between using your phone as a second brain and letting your own memory go slack. We dig into the MIT study that scanned essay writers' brains and found the ChatGPT group remembered the least of what they wrote, what London cabbies' brains looked like before satellite navigation, why movement drives brain-derived neurotrophic factor (BDNF), and why racket sports and dance sit at the top of the longevity list. You'll also learn Jim's BUILD...

Full show notes: BenGreenfieldLife.com/jubilee

In this episode, John Jubilee makes the case that almost everything you have been told about hydration is beside the point. His argument is that the water is not the problem, the cell is: that a membrane gets progressively harder to penetrate as you age, that your water and your supplements simply bounce off it, and that until you change the membrane itself, nothing else you do gets in. He arrived at that after a decade of doing everything right, a gallon of water a day and a thousand dollars a...

Full show notes: bengreenfieldlife.com/bolt

In this episode, Chandler Bolt and I talk about how we've each landed on almost identical daily systems for running a company, and the one place we still disagree. Chandler makes the case that a book is a business asset rather than an income stream, explains what it actually costs to buy your way onto the New York Times list, and then walks through the routine underneath all of it: a nap he hasn't skipped in years, a morning he refuses to let anyone schedule over, and a phone that geofences...

Full show notes: bengreenfieldlife.com/pharma

In this special repeat episode, Dr. Sandra Kaufmann breaks down which pharmaceuticals mimic the effects of things you already do for your health: what replaces a sauna session, what replaces a fast, what replaces a cold plunge (use code BENFORGE for $500 off select products), and what she takes with meals to blunt the damage from glucose spikes. I'm re-airing it now because of a new Nature paper finding that lithium is a naturally occurring brain nutrient, and that losing it may be one of the earliest steps toward Alzheimer's, at a...

Full show notes: bengreenfieldlife.com/505

In this solosode, you'll get the latest on microplastics, spinal disc health, and what a heart scan sees that a cholesterol panel misses. A new seven-day trial pitted five plastic-avoidance strategies against each other, and the results tell you exactly where to spend your effort if you can't overhaul everything at once. You'll hear which plastic sources matter most and what I now take before bed with BrocElite® (use code BEN for 25% off your first month) to help clear microplastics from tissue. Then I get personal about my back. I'll walk you t...

Full show notes: https://bengreenfieldlife.com/holyhealth

In this episode with Justin Roethlingshoefer, you'll hear from a former NHL performance coach turned health entrepreneur whose new book, Holy Health, is the one I chose for my father-son book club this month. This is not another eat-honey-and-drink-milk Bible health book. Justin is a genuine biohacker who works with pro athletes worldwide, and he has woven deep spiritual and physiological science into the same framework.

You'll learn why the modern obsession with optimization can quietly become idolatry, how the drive to control your metrics keeps your nervous...

Full show notes: https://bengreenfieldlife.com/504

In this solosode, you'll get the latest research on three questions I keep getting asked. First, seed oils: a brand-new randomized controlled trial put 52 adults on either a low or a typical Western intake of linoleic acid for 12 weeks, and the results are important less for what they found than for what they didn't. You'll hear why arachidonic acid didn't move, why EPA dropped instead, what that does to your inflammatory balance, which seed oils I still think are worth avoiding, and the one dietary adjustment that matters most if seed...

Full show notes: https://bengreenfieldlife.com/juliepodcast

In this episode with Julie Gibson Clark, I'm highlighting a throwback conversation because the gap it exposed has only gotten wider. There's a leaderboard called the Rejuvenation Olympics where people submit a blood test that measures how fast they're aging. When we recorded, Julie was a 55-year-old single mom in Phoenix making under $100,000 a year, sitting at number two in the world, aging at roughly two-thirds the speed of the calendar, and ahead of people like Bryan Johnson, who was spending $2 million a year chasing the same number. Her budget...

Full show notes: https://bengreenfieldlife.com/dylan

In this episode with Dylan Gemelli, you'll hear one of the wildest origin stories in the health world. Dylan went from college athlete to Milan model to cocaine dealer to a 15-year prison sentence, and came out on the Fourth of July with two felonies, no job prospects, and a decision to start over. Within a year he had a million YouTube subscribers explaining compounds almost nobody was talking about yet, and today he hosts the number one health and fitness podcast in the country.

You'll also get...

Full show notes: https://bengreenfieldlife.com/blackseedoil

In this episode with Dr. Michael Murray, one of the most respected figures in natural medicine and the formulator of ThymoQuin®, you'll discover the science behind black seed oil: what thymoquinone actually is, why the full spectrum of the seed's compounds matters more than chasing a single active ingredient, and why it may be the most powerful adaptogen yet measured for lowering cortisol, dropping the stress hormone 22 to 44% in stressed people. You'll hear how it supports your gut by calming harmful bacteria without wiping out the good ones, the surprising d...

Full show notes: https://bengreenfieldlife.com/sunpodcast

In this episode, journalist Rowan Jacobsen, author of In Defense of Sunlight, challenges everything you thought you knew about sun exposure. Modeled after Michael Pollan's In Defense of Food, his book argues we've been gaslit into a "zero-sun policy" the science does not actually support. You'll hear why melanoma is tied to intermittent sunburns rather than steady sun, the surprising 2024 research suggesting UVB may be protective while UVA is the real concern, and how office culture, window glass, and car windows may all be hidden pieces of the skin cancer...

Full show notes: https://bengreenfieldlife.com/peptides2026

In this episode with Dr. Matt Cook, recorded days after he returned from Washington, D.C., you'll get a breakdown of what just happened to peptides in the United States. You'll hear what the FDA's Pharmacy Compounding Advisory Committee actually voted on, why seven popular peptides were pulled two years ago, which six of the seven were just recommended for the bulk list, which one was left off, and what all of it means for your ability to get peptides legally from a pharmacy instead of the gray market.

Full show notes: https://bengreenfieldlife.com/nickpodcast

In this episode, you'll get a practical, plain-language tour of breathwork with Nick Sweeney, a breathwork coach who rebuilt his body with breath after a college bike accident left him unable to walk. You'll learn his Vortex Breath and the Fibonacci counting behind it, why slow breathing is really cardiovascular training that may predict how long you live, how to pair breath with fascia and mobility work, his routines for better sleep and for combining sauna, breath, and cold safely, where he lands on the cold plunge debate, why the...

Full Show Notes: https://bengreenfieldlife.com/503

In this solosode, you'll get the latest research on the questions I hear most: whether the peptide BPC 157 can cause cancer, the body fat percentages people rate most attractive for men and women (and how low is too low), how a "dad bod" before conception can affect your future kids' health, how "myo-reps" deliver the same strength and size gains in a fraction of your gym time, and whether creatine is bad for your kidneys. You'll hear why BPC 157's blood-vessel growth is not the same as the way cancer feeds...

Full show notes: https://bengreenfieldlife.com/floridahunt

In this episode, recorded at Lightsey Family Ranch in Venus, Florida, I'm joined by my sons River and Terran and repeat guest Adam Wenguer, founder of Element Health, for the first stop in a father-and-sons adventure project inspired by former Boundless guest Sahil Bloom's The 5 Types of Wealth.

You'll hear the ethics and deeper meaning of hunting, why harvesting your own meat changes your relationship with food, and how to cook wild game so it actually tastes great. We also get into spearfishing and free diving, teaching kids...

Full show notes: https://bengreenfieldlife.com/saunapodcast

In this episode with Luke Chapman and Owen Buchanan, founders of Western Sol, you'll hear the story behind the custom sauna I recently had built in my backyard in Idaho, and the story behind the company itself, which started when a mold exposure in Hawaii sent Luke into daily sauna use. You'll gain insights into the actual science of heat shock proteins and dynorphins (the opioid peptides your body releases under heat stress), why most sauna wood is loaded with VOCs, and how thermally pressed aspen and spruce sourced from...

Full show notes: https://bengreenfieldlife.com/signalspodcast

In this episode with Tom Moss, founder and CEO of Vital Signals, you'll hear how a near-fatal hypertensive crisis during a family vacation became the founding moment for a device that may finally solve the problem of getting accurate blood pressure readings in real life without a cuff. Tom explains why blood pressure is the single most important indicator of long-term cardiovascular health and yet one of the least accurately measured, what the cuff gets wrong, and how Vital Signals achieved the scientific breakthrough that other companies failed to crack...

Full show notes: https://bengreenfieldlife.com/lotus

In this episode with KJ Dhaliwal of Lotus AI, you'll hear how translating his immigrant parents' doctor visits as a child and years spent bouncing through fragmented specialty care as a teenager after a disc herniation shaped his mission to give 100 million Americans free, world-class primary care using AI. KJ breaks down how Lotus AI pulls your entire medical history from every clinic and hospital you've ever visited in minutes, unifies it with your wearables and genetic data, and makes it available to both a conversational AI and a network...

Full show notes: https://bengreenfieldlife.com/tectonpodcast

In this episode with Dr. Mike Chesne, founder of Tecton Ketones™, you'll hear how a traumatic brain injury sustained in combat led him from Army Special Forces medic to ketone biochemist, and why he eventually built what he believes is a meaningfully better exogenous ketone molecule than anything else currently on the market. We get into the real biochemical differences between ketone salts, ketone esters, and bioidentical beta-hydroxybutyrate, why the liver matters so much in how these molecules get metabolized, and a full walkthrough of Tecton's plant-based liposomal delivery system. Yo...

Full show notes: https://bengreenfieldlife.com/502

In this solosode, you'll explore how to make peace with tinnitus after acoustic trauma, including the half dozen different root causes that can drive it and the specific supplements and technologies with research behind them, why cardiovascular fitness itself seems to protect your hearing as you age, and whether tattoos are actually as risky as people think, from the heavy metals hiding in colored ink to what a major 2024 study found about tattoos and lymphoma risk.

I also break down a new study showing you can get the same...

Full show notes: https://bengreenfieldlife.com/zenospodcast

In this episode with Mazen Karnaby, founder of Zenos Health, you'll hear how a pharmacist who spent 17 years filling prescriptions behind the counter ended up building one of the more rigorously formulated supplement lines on the market. You'll hear his full story, including a melanoma diagnosis that reframed his entire approach to health, get into the formulation details behind his most talked about products, from the creatine gummies people get genuinely addicted to, to UriZen for kidney and urinary tract support, VZen for the vaginal microbiome, and BeautyZen for skin...

Full show notes: https://bengreenfieldlife.com/mitrix

In this episode with Tom Benson, founder and CEO of Mitrix, you'll hear why mitochondrial decline may be the actual root cause of aging rather than just a downstream symptom of it, and why most of the drugs developed so far to address it don't touch the real problem: damaged mitochondrial DNA. We discuss how Tom's company grows new, healthy mitochondria inside a bioreactor using banked stem cells, what mitochondrial transplantation actually looks like in real human cases already happening today, and the mouse study that gives this episode its...

Full show notes: https://bengreenfieldlife.com/jimmypodcast 

In this episode with Jimmy St. Louis, you'll hear how a former NFL player, US Olympic rowing trials competitor, and four-time CrossFit regionals athlete built his career around defining the standard of care in longevity medicine. Jimmy shares the full arc of his path from a three-sport young athlete through three ACL tears, into a spine surgery business that performed 100,000 procedures, and then into Agentis Longevity, a company built around acquiring the best longevity clinics in the country and unifying them under one consistent set of protocols. You will also g...

Full show notes: https://bengreenfieldlife.com/bretthurt

In this episode with Brett Hurt, serial tech entrepreneur and author of Love Conquers Fear, you'll hear how he went from coding obsessively at seven to building one of the early internet's most popular games, surviving the dot-com bust, orchestrating two major exits, data.world to ServiceNow and Bazaarvoice's billion-dollar IPO, and experiencing a psychedelic awakening at 50 that redirected his entire life.

You will also hear his vision for what an Age of Abundance looks like in practice, from solar energy and robotics to brain-computer interfaces and the...

Full show notes: https://bengreenfieldlife.com/tim2026

In this episode with repeat guest Tim Gray, you'll hear why the smartest biohackers are now removing more than they are adding, what paying attention to microplastics and environmental toxins in your own home and blood actually reveals, and why sulforaphane is making a comeback as a potential microplastic clearance tool. You'll also get a breakdown of the most interesting technologies coming to the Health Optimisation Summit this September, now in its first-ever three-day format, from hydrogen inhalation and bio-energy stimulation to hands-free vagus nerve stimulation, PEMF, STEMREGEN, and a...

Full show notes: https://bengreenfieldlife.com/jaspr2026

In this replay episode, Mike Feldstein makes the case that clean air may be the single most overlooked variable in your health, sleep, and cognitive performance stack.

Mike draws on firsthand experience from the LA wildfires (testing air, soil, and water after thousands of homes burned), revealing why most standard air purifiers, water tests, and insurance claims completely miss the real threat. You'll also discover how clean air has eliminated snoring and resolved sleep apnea symptoms in real households, what cognitive research on chess grandmasters reveals about pollution...

Full show notes: https://bengreenfieldlife.com/marapodcast

In this episode, you will hear the origin story of Mara Labs, a company built around sulforaphane, the active compound found in broccoli that has been studied across thousands of papers covering almost every major chronic disease, and why most people are not actually getting it from their broccoli supplements. You will discover why the way your broccoli supplement is made determines whether any of it reaches your cells at all, what dose of the active compound moves the needle on inflammation, detox, and cellular defense, and how a single...

Full show notes: https://bengreenfieldlife.com/dralbert

In this episode, Dr. Pradeep Albert breaks down the science behind HarmonIQ, formerly Hapbee, a wearable wellness company using frequency-based technology to help you access specific physiological states on demand, from deeper sleep and sharper focus to stress reduction and addiction support, all without ingesting anything. This episode also marks the official launch of HarmonIQ and its new pet-focused line Hapbee Pets.

You'll discover why quality sleep without pills is the non-negotiable foundation on which every advanced longevity therapy sits, what Dezawa MuseCells are doing to cartilage and...

Full show notes: https://bengreenfieldlife.com/501

In this solosode, I walk you through five research topics I've been tracking so you can make smarter, more informed decisions about your health. You'll explore why varying your exercise routine may matter as much as total volume, how toe strength connects to everything from heel pain to sprint power, what plaque composition data reveals that lipid markers alone cannot tell you, how CBN stacks up against CBD and pharmaceutical sleep aids for insomnia, and what a new mouse study suggests GLP-1 drugs are actually doing to lean body mass. I...