Genetics Unzipped

40 Episodes
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By: The Genetics Society

From Mendel's peas to personal genome sequencing, Genetics Unzipped brings you stories from the world of genes, genomes and DNA. In association with The Genetics Society.

Next Generation Sequence
#27
01/25/2024

Please fill out our listener survey at geneticsunzipped.com/survey before January 31st

This episode is all about the next generation, as we meet three up-and-coming scientists who have been supported by the Genetics Society, and learn all about Bermuda skinks, the Black Death and life after a genetics PhD.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

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This episode of Genetics Unzipped was written, presented and produced by Sally Le Page with audio production by Emma Werner.


The battle for biology
#26
01/11/2024

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In this episode, we talk to Greg Radick from the University of Leeds to explore the impact that Gregor Mendel and his populariser William Bateson have had on the past century of genetics, and ask whether there could have been a more Weldonian view of the world.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

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This episode of G...


2023 Unzipped
#35
12/21/2023

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As 2023 draws to a close, we’re bringing you a smorgasbord of previously unaired clips from some of our favourite interviews this year.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

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This episode of Genetics Unzipped was written, presented and produced by Sally Le Page & Kat Arney with audio production by Emma Werner.

This podcast is cre...


Genes, junk and the ā€˜dark genome’
#24
12/14/2023

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We discover how 500,000 whole genome from UK Biobank will help medical research, plumb the depths of the ā€˜dark genome’ with Nucleome, and Larry Moran tells us how much of our DNA is just junk.

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Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

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This episode of Genetics Unzipped was written and prese...


40 years of HIV
#23
11/30/2023

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With 2023 marking 40 years since the discovery of HIV, we're looking back over four decades of AIDS, from the earliest whispers of a mysterious new disease to fighting back against this deadly virus.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

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This episode of Genetics Unzipped was written, presented and produced by Emma Werner in collaboration with Sally Le Page and w...


Dumb luck
#22
11/16/2023

Author and science journalist Rebecca Coffey chats with us about some amazing adaptations and Darwinian delights from her book, Beyond Primates. She tells us about wasp facial recognition genes, how yeast epigenetics explain the Dutch Hunger Winter and a dinner party tale of spider cannibalism.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written, presented and produced by Sally Le Page with audio production by Emma Werner.

This podcast is created by First Create the Media for the G...


Time of your life
11/02/2023

In this episode we’re clocking in to chat about the genetics of circadian rhythms. How can molecules tell the time, why don’t we have drugs for jet lag yet and could a midnight snack stop malaria in its tracks?

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written, presented and produced by Sally Le Page with audio production by Emma Werner.

This podcast is created by First Create the Media for the Genetics Society - one of th...


That's so extra
#20
10/19/2023

We explore the weird and wonderful world of extrachromosomal DNA - what it is, what it does, and why it breaks the normal rules of inheritance.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented and produced by Kat Arney with audio production by Emma Werner.

This podcast is produced by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, training, teaching and public engagement in a...


Food for the future
#19
10/05/2023

We’re finding out how plants adapt to a changing environment, and how we might be able to give them a helping hand so that we can keep feeding the world sustainably in the future.

Full show notes, transcript and references online at GeneticsUnzipped.com

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented and produced by Kat Arney with audio production by Emma Werner.

This podcast is produced by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to...


BONUS - Hormones: The Inside Story - Season 3
09/21/2023

In this bonus episode, we’re bringing you the third instalment of Hormones: The Inside Story, Season 3. This podcast is produced for the Society for Endocrinology by the same team behind Genetics Unzipped.

Find it on Podbean, Apple Podcasts, Spotify or wherever you get your podcasts.

In this episode, Dr Sally Le Page investigates the role of genetics, ethnicity and maternal environment on type 2 diabetes, with our guests Dr InĆŖs Cebola, Dr Shivani Misra and Dr Lorna Smith.

This week, we investigate the role of genetics, ethnicity and maternal environment on...


An Evolutionary Revolutionary
#18
09/07/2023

We’re exploring the epic life of Alfred Russel Wallace; adventurer, naturalist and co-discoverer of natural selection. Biologist and author, Jim Costa, recounts the life of this often forgotten founding father of evolution.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page.

This podcast is created by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, tra...


Vax to the future
#17
08/24/2023

We look at the science behind DNA and RNA vaccines - How do they work? What can they do? And how can they be made at scale so that more people around the world can benefit from them? With John Tregoning from Imperial College London, Christian Ottensmeier from the University of Liverpool, and Lisa Caproni from Touchlight.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le P...


Double helix double crossing
#16
08/10/2023

Kat Arney chats with Professor Matthew Cobb about what really happened between James Watson, Francis Crick and Rosalind Franklin during the discovery of the double helix structure of DNA.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page.

This podcast is produced by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, training, t...


Making Big Science Happen
#15
07/27/2023

We’re going behind the scenes at the Sanger Institute with Cordelia Langford, Director of Scientific Operations, to find out what it takes to make Big Science happen, and hear the stories behind the sequencing.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page.


This podcast is produced by First Create the Media for the Genetics Society - one of the oldest lea...


Tracking COVID and tackling obesity
#14
07/13/2023

We’re chatting with two of this year’s Genetics Society award winners - Cecilia Lindgren, who’s an expert on the genetics of obesity and metabolic disorders, and Lucy van Dorp, who has spent the past three years tracing the spread of SARS-CoV-2 around the world.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page.


This podcast is produced by First Create...


Kings, car parks and consent
#13
06/29/2023

We’re venturing into ancient territory and archaeological digs, excavating the complex ethics of extracting and sequencing DNA from human remains. We chat to Prof. Turi King about her role uncovering the body King Richard III and who decides which research gets done.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page.


This podcast is created by First Create the Media for the Genetics Society - one of...


Da Vinci’s DNA
#12
06/15/2023

We’re taking a journey into the world of art and artefacts, unearthing the genetic secrets of long-dead legends like Da Vinci, Van Gogh and Beethoven.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page.

This podcast is produced by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, training, teaching and public eng...


Meet the DNA Detectives hunting the causes of cancer
#611
06/01/2023

We’re chasing down the perpetrator of a scientific Whodunnit, joining the DNA detectives on the hunt for the causes of cancer.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page.

This podcast is produced by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, training, teaching and public engagement in all areas of...


Space invaders
#10
05/18/2023

In this episode we’re going microscopic, exploring what tiny tardigrades can teach us about desiccation, vaccine delivery … and even space travel!

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page.


This podcast is created by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, training, teaching and public engagement in all areas of genetics.


S609: Raiders of Noah’s Ark
#9
05/04/2023

In this episode we’re becoming chromosomal criminals and learning about how researchers are stealing genes from the animal kingdom and using them to improve human health. From 13-lined ground squirrels teaching us how to recover from heart attacks, to bowhead whales showing us how to avoid cancer, there’s a lot geneticists can learn from Mother Nature.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page.

This podca...


BONUS Re-release
#22
04/27/2023

To celebrate DNA Day, we are rereleasing an episode from series 3, called The Past, Present, and Future of the Human Genome Project, when Kat interviewed the director of the US National Human Genome Research Institute, Dr Eric Green about his work on the Human Genome Project from its very inception.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This podcast is created by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, training, teaching and public e...


Pop goes the genome!
#8
04/20/2023

We take a leftfield look at public communication of genetics, exploring how the science of DNA turns up in popular culture from comics and music to cakes, with Great British Bake Off winner Syabira Yusoff.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page.

This podcast is produced by First Create the Media for the Genetics Society - one o...


Chris Hemsworth took a genetic test for Alzheimer's.
#7
04/06/2023

We’re discussing Chris Hemsworth’s recent Alzheimer's risk findings and the pros and cons of direct-to-consumer DNA testing with genetic counsellor and host of the podcast DNA Today, Kira Dineen.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page.


This podcast is created by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, training, teach...


Bye-bye boys
#6
03/23/2023

We’re saying bye-bye to the boys, and exploring whether new gene technologies and climate change will make males extinct.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page.


This podcast is created by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, training, teaching and public engagement in all areas of genetics.


GMO or GM NO?
#5
03/09/2023

We're exploring the ethics and regulations of genome editing. What is allowed? What shouldn't be? And who should get to decide? Plus we explore a new exhibit on the topic that lets the public have their say.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page.


This podcast is created by First Create the Media for the Genetics Society - one of the oldest learned s...


The diagnosis odyssey
#4
02/23/2023

We’re off on a journey to the world of rare genetic disorders, exploring the diagnostic odyssey that patients go on in search of answers, research into variants of unknown significance and new approaches for treating the rare disease Aicardi-GoutiĆØres Syndrome (AGS)

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page.


This podcast is produced by First Create the Medi...


Confident, competent or confused
#3
02/09/2023

How much do you know about genetics? In this episode we’re sharing the results of a large survey asking the UK public what their opinions are, what they know, or more importantly, what they think they know about genetics and what that means for society.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented by Sally Le Page with audio production by Emma Werner and Sally Le Page.


This podcast is produced by First Cre...


S6.02: Would you Adam and Eve it?
#2
01/26/2023

We’re going back to the very genesis of our species in search of the genetic Adam and Eve. Who were they? When and where did they live? Were there really just two of them? And how should we really be referring to these ancient ancestors anyway?

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page.

This podcast is produced by Fir...


Baby brain, baby body
#1
01/12/2023

We’re going back to the womb to explore the genetics of how to make babies - from finding out how birthweight is linked to the risk of diabetes to investigating the multifaceted role of the hormone prolactin in pregnancy and the role of epigenetics in the placenta.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page.


This podcast is produced by Fir...


S525: 2022 Unzipped
#25
12/15/2022

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written, presented and produced by Sally Le Page.


This podcast is created by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, training, teaching and public engagement in all areas of genetics.


Bats, boats and buried bodies
#24
12/01/2022

In this episode we’re testing the air for tigers and digging up dead bodies as we explore the exciting new field of environmental DNA. Dr Sally Le Page chats with Prof. Elizabeth Clare about sampling the DNA of rare species from the air, and Dr Kirstin Meyer-Kaiser and Charles Konsitzke tells us about their project using eDNA to recover the missing bodies of fallen service personnel.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written, presented and produced by Emm...


Living with the Eugenic Past: Michele Goodwin
11/27/2022

This podcast is part of a miniseries of interviews with speakers from the 2022 annual conference of the Adelphi Genetics Forum - a learned society that aims to promote research and discussion concerning the scientific understanding of human heredity. Formerly known as the Galton Institute, and before that, the Eugenics Education Society, the society has changed its name to the Adelphi Genetics Forum to firmly reject and distance itself from the discredited and damaging ideas of its namesake, Francis Galton – widely viewed as the founder of eugenics.

The last lecture of the day was given by Michele Goodwin...


Living with the Eugenic Past: Joe Cain
11/26/2022

This podcast is part of a miniseries of interviews with speakers from the 2022 annual conference of the Adelphi Genetics Forum - a learned society that aims to promote research and discussion concerning the scientific understanding of human heredity. Formerly known as the Galton Institute, and before that, the Eugenics Education Society, the society has changed its name to the Adelphi Genetics Forum to firmly reject and distance itself from the discredited and damaging ideas of its namesake, Francis Galton – widely viewed as the founder of eugenics.

Much of Francis Galton’s academic life is associated with University Coll...


Living with the Eugenic Past: Anneke Lucassen
11/25/2022

This podcast is part of a miniseries of interviews with speakers from the 2022 annual conference of the Adelphi Genetics Forum - a learned society that aims to promote research and discussion concerning the scientific understanding of human heredity. Formerly known as the Galton Institute, and before that, the Eugenics Education Society, the society has changed its name to the Adelphi Genetics Forum to firmly reject and distance itself from the discredited and damaging ideas of its namesake, Francis Galton – widely viewed as the founder of eugenics.

Anneke Lucassen is Professor of Genomic Medicine & Director of the Centre fo...


Living with the Eugenic Past: Brian Donovan
11/24/2022

This podcast is part of a miniseries of interviews with speakers from the 2022 annual conference of the Adelphi Genetics Forum - a learned society that aims to promote research and discussion concerning the scientific understanding of human heredity. Formerly known as the Galton Institute, and before that, the Eugenics Education Society, the society has changed its name to the Adelphi Genetics Forum to firmly reject and distance itself from the discredited and damaging ideas of its namesake, Francis Galton – widely viewed as the founder of eugenics.

Dr Brian Donovan is a senior research scientist at BSCS Science le...


Living with the Eugenic Past: Adam Rutherford
11/23/2022

This podcast is part of a miniseries of interviews with speakers from the 2022 annual conference of the Adelphi Genetics Forum - a learned society that aims to promote research and discussion concerning the scientific understanding of human heredity. Formerly known as the Galton Institute, and before that, the Eugenics Education Society, the society has changed its name to the Adelphi Genetics Forum to firmly reject and distance itself from the discredited and damaging ideas of its namesake, Francis Galton – widely viewed as the founder of eugenics.

Dr Adam Rutherford is a writer and broadcaster, and is an ho...


Living with the Eugenic Past: Elaine Riddick
11/22/2022

CONTENT NOTE: This interview includes discussion of rape, forced sterilisation and first-hand experience of state-sanctioned eugenic policies.

This podcast is part of a miniseries of interviews with speakers from the 2022 annual conference of the Adelphi Genetics Forum - a learned society that aims to promote research and discussion concerning the scientific understanding of human heredity. Formerly known as the Galton Institute, and before that, the Eugenics Education Society, the society has changed its name to the Adelphi Genetics Forum to firmly reject and distance itself from the discredited and damaging ideas of its namesake, Francis Galton – widely vi...


Living with the Eugenic Past: Turi King
11/21/2022

This podcast is part of a miniseries of interviews with speakers from the 2022 annual conference of the Adelphi Genetics Forum - a learned society that aims to promote research and discussion concerning the scientific understanding of human heredity. Formerly known as the Galton Institute, and before that, the Eugenics Education Society, the society has changed its name to the Adelphi Genetics Forum to firmly reject and distance itself from the discredited and damaging ideas of its namesake, Francis Galton – widely viewed as the founder of eugenics.

In this first episode, I spoke to Turi King, the President of...


Birds and bees… and sardines
#23
11/17/2022

In this episode we’re taking a look at the birds and the bees - not like that! - from the unusual migratory habits of European blackcaps and the ā€˜greatest shoal on earth’ to the division of labour in a beehive, we’ll be exploring the role that genetics plays in shaping animal behaviours.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twitter @GeneticsUnzip

This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page.


This p...


Little Shop of Genetic Horrors
#22
11/03/2022

There’s something unnatural about carnivorous plants. We’re so used to plants being at the bottom of the food chain, that to see them trapping, killing and eating animals seems to go against the laws of nature. But of course, carnivory in plants is very real and has evolved multiple times in response to a lack of nutrients. In this episode we’re looking at how carnivorous plants work, what lives inside the digestive juices, and even a future with carnivorous crops.

Full show notes, transcript and references online at GeneticsUnzipped.comĀ 

Follow us on Twit...