The NACE Clinical Highlights Show
Engage with expert NACE faculty for discussions about current clinical strategies for common and rare health conditions that you can use in clinical practice immediately, and that work for you and your patients.
NACE Journal Club #28
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:
1. Impact of a Smartwatch Hypertension Notification Feature for Population Screening.
JAMA 2026. Discussion by:Â
Guest:
Erin Russell, MDÂ
Resident - Abington Family Medicine Residency ProgramÂ
Jefferson Health - Abington
2. A guide to consumer-grade wearables in cardiovascular clinical care and population health for non-experts. Discussion by:Â
Guest:
...
NACE Journal Club #27
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:
1. USDA Dietary Guidelines 2025-2030. Discussion by:Â
Guest:
Phillip Leiberman, MD
Resident Family Medicine Residency ProgramÂ
Jefferson Health - Abington
2. The Effect of Substituting Wate for Artificially Sweetened Beverages on Glycemic and Weight Measures in People With Type 2 Diabetes: The Study of Drinks With Artificial Sweeteners (SODAS), a Randomized Trial – Diab...
NACE Journal Club #26
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:
1. Candesartan for Migraine Prophylaxies. The Lancet 2025 . Discussion by:
Guest:
Max Schidt, MD
Resident - Family Medicine Residency Program
Jefferson Health - Abington
2. One vs two dose HPV vaccination for prevention of HPV infection – The New England Journal of Medicine 2025. Discussion by:
Guest:
Neil Skolnik, MD
APAPP From Idea to Abstract
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APAPP Welcome to the ICU
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CME/CE Podcast: Responding to the Science – Biologics in Practice in COPD
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/responding-to-the-science-biologics-in-practice-in-copd-10511
Summary
This enduring podcast activity provides pulmonologists and clinicians managing COPD with timely updates on the evolving role of biologics management. Featuring expert discussions, the program explores recent GOLD guideline revisions, the integration of new and emerging biologic therapies, and evidence-based decision-making based on clinical trial data and real-world practice.
Covering guidelines, clinical trials, and clinical scenario, this activity emphasizes...
CME/CE Podcast: Personalized Antidepressant Choices for Better Outcomes
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/personalized-antidepressant-choices-for-better-outcomes-in-mdd-10266
Summary
Emphasizing a measurement-based, patient-centered model, this is an enduring podcast/webcast designed for psychiatrists who seek to refine their approach to managing major depressive disorder (MDD). Despite an expanding array of pharmacologic options, many patients continue to experience side effects and residual symptoms that undermine adherence and long-term recovery. Led by Drs. Gregory Mattingly and Gerald Maguire, this activity equips clinicians...
CME/CE Podcast: Harnessing the Night to Win the Day in ADHD
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/adhd-sleep-and-symptom-control-10355
Summary
Early-morning symptom control remains a critical gap in ADHD management, often contributing to family stress and impaired daily functioning. In this podcast/webcast activity, Dr. Joel Young and Jo Hughes, DMSc, PA-C, CAQ-PSY, explore the limitations of traditional ADHD medications in achieving full-day coverage and discuss available strategies to improve early-morning outcomes. Learners will gain practical insights into the clinical use...
NACE Journal Club #25
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:
1. FDA change in Boxed Warning Label for Hormone Replacement Therapy. Discussion by:
Guest:
Anupriya Grover Wenk, DO
Faculty - Family Medicine Residency Program
Jefferson Health - Abington
2. Evolocumab in Patients without a Previous Myocardial Infarction or Stroke – The New England Journal of Medicine 2025. Discussion by:
Guest:
APAPP When is an Oral Appliance Right for your OSA Patient
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CME/CE Podcast: Personalizing ADHD Management Using MPH
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/personalizing-adhd-management-using-methylphenidate-10448
Summary
Effective ADHD management demands more than symptom control—it requires personalized treatment strategies aligned with the patient’s unique daily functional needs. Through clinical case examples and pharmacologic comparisons, learners will explore how tailoring treatment using immediate-release (IR), extended-release (ER), and delayed-release/extended-release (DR/ER) methylphenidate (MPH) formulations can optimize symptom control aligned with patients’ daily routines and responsibilities. In this podcas...
APAPP AI in Lung Cancer Screening
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NACE Journal Club #24
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:
1. Step Accumulation Patterns and Risk for Cardiovascular Events and
Mortality Among Suboptimally Active Adults – Annals of Internal Medicine 2025. Discussion by:
Guest:
Kathryn Donnelly, DOÂ
Resident - Family Medicine Residency Program
Jefferson Health - Abington
2. Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Obesity – The New England Journal of Medicine 2025. Discus...
NACE Journal Club #23
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:
1. Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity – The New England Journal of Medicine 2025. Discussion by:
Guest:
Anupryia Grover-Wenk, DO
Resident - Family Medicine Residency Program
Jefferson Health - Abington
2. Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2
Diabetes. – The New England Jour...
APAPP ILD in Scleroderma
Please visit http://naceonline.com to engage in more live and on demand CME/CE content.
APAPP Know your Nodules: Personalize. Prioritize. Prevent.
Please visit http://naceonline.com to engage in more live and on demand CME/CE content.
NACE Journal Club #22
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:
1. Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function: The US POINTER Randomized Clinical Trial JAMA 2025. Discussion by:
Guest:
Philip Lieberman, MD
Resident- Family Medicine Residency Program
Jefferson Health - Abington
2. Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity — A Phase 2 Trial. New England Journal of Medicine 2025 Discussion by:
CME/CE Podcast: Targeting the Root Cause: New & Emerging Therapies for Menopausal VMS
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/targeting-cause-emerging-therapies-menopausal-vms-10267
Summary
This enduring podcast activity explores groundbreaking advancements in the treatment of menopausal vasomotor symptoms (VMS), emphasizing non-hormonal therapies. Dr. Andrea Singer and Dr. Genevieve Neal-Perry discuss the underlying biology of menopause, particularly the role of neurokinin (NK) receptors, and introduces the science behind new therapeutic agents, as well as their clinical trial data.
Content Update Disclaimer: Since...
CME/CE Podcast: Consider Personalizing Care: Identifying the Right Patients for New Menopause Treatments
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/personalizing-care-identifying-the-right-patients-for-new-treatments-10268
Summary
Dr. Genevieve Neal-Perry and Dr. Andrea Singer focus on practical strategies in the personalized management of menopausal vasomotor symptoms (VMS). The discussion covers the importance of routine and individualized screening for VMS, with attention to healthcare disparities and the diverse ways menopause is discussed and experienced across populations, before covering patient selection criteria for newer non-hormonal treatments.
Content...
APAPP Professional Development for APPs: Building skills beyond the bedside
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NACE Journal Club #21
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:
1. Antihypertensive Medication Timing and Cardiovascular Events and Death The BedMed Randomized Clinical Trial JAMA 2025. Discussion by:
Guest:
Susan Kuchera, MD
Director of the Family Medicine Residency Program
Jefferson Health - Abington
2. Weekly Fixed-Dose Insulin Efsitora in Type 2 Diabetes without Previous Insulin Therapy. 2025. Discussion by:
Guest:
Eden Miller, MD...
CME/CE Podcast: Cognition in MDD The Missing Piece to Full Recovery
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
http://mycme.com/courses/the-cognitive-side-of-major-depressive-disorder-10221
Summary
Despite significant improvements in mood symptoms, many patients with MDD continue to experience persistent residual symptoms—particularly cognitive impairments—that hinder full functional recovery. In this PsychTalk podcast/webcast episode, Drs. Gregory Mattingly and Roger McIntyre discuss the often-overlooked role of cognitive dysfunction in MDD recovery, highlighting how these impairments correlate strongly with reduced workplace productivity, social withdrawal, and elevated relapse risk, ulti...
CME/CE Podcast: Managing the Stimulant Crisis: Clinical Strategies and Real-World Impact
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/strategies-and-real-world-impact-of-the-stimulant-crisis-10220
Summary
The stimulant medication shortage has introduced new challenges in managing ADHD, affecting both patients’ access to essential treatments and clinicians’ ability to provide consistent care. In this PsychTalk podcast/webcast episode, Drs. Gregory Mattingly and Roger McIntyre explore the impact of these shortages, particularly on cognitive functioning, treatment continuity, and daily life for individuals with ADHD. Their discussion also examines stimulant misu...
CME/CE Podcast: Mitigating CKD Progression: What the Latest Data Reveals
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/the-latest-data-in-ckd-progression-10197
Summary
Emerging evidence highlights the potential of GLP-1 receptor agonists (GLP-1 RAs) to slow CKD progression and reduce cardiovascular and kidney-related mortality in patients with type 2 diabetes (T2D) and chronic kidney disease (CKD). Yet, despite updated guidelines, these therapies remain underused. This program will explore the latest clinical data supporting the role of GLP-1 RAs in risk mitigation and provide practical strategies...
APAPP Lung Transplant 101: Transplant committee edition
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NACE Journal Club #20
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:
1. Effects of Combining Coronary Calcium Score With Treatment on Plaque
Progression in Familial Coronary Artery Disease A Randomized Clinical Trial JAMA 2025. Discussion by:
Guest:
Michael J. Blaha, MD, MPH
Professor of Cardiology and Epidemiology and presently serves as the
Director of Clinical Research for the Johns Hopkins Ciccarone Center for the
...
CME/CE Podcast: Your Questions on Chronic Spontaneous Urticaria
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/answers-in-chronic-spontaneous-urticaria-10190
Summary
In this short CE/CME activity, moderator Dr. Brad Glick works with dermatology expert Dr. Gil Yosipovitch to answer your top questions regarding chronic spontaneous urticaria, as gathered from the 2025 NACE Conversations in Dermatology symposium. Questions cover diagnosis, treatment individualization, and more!
Learning Objectives
At the conclusion of this activity, participants should be better able to:
CME/CE Podcast: COPD Inflammation & Exacerbations: Your Questions Answered
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/copd-inflammation-exacerbations-your-questions-answered-10143
Summary
Rejoin the conversation on COPD, inflammation, and new and emerging agents as two of our expert faculty come together to answer your top questions. Questions submitted from the recent Conversations in Primary Care live virtual symposia guide the discussion as we dig a bit deeper on type 2 inflammation, changes in COPD management, and new and emerging agents – including recently approved biologic agents – for...
APAPP An Asthma Focus on SMART, AIR & PARTICS: Asthma Committee Edition
Please visit http://naceonline.com to engage in more live and on demand CME/CE content.
NACE Journal Club #19
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:
1. Lepodisiran — A Long-Duration Small Interfering RNA Targeting Lipoprotein(a) - New England Journal of Medicine 2025. Discussion by:
Guest:
Steven E. Nissen, M.D.,
 Chief Academic Officer of the Heart and Vascular Institute at the Cleveland Clinic
Professor of Medicine at the Lerner College of Medicine
2. Genitourinary Syndrome of Menopause: AUA/SUFU...
CME/CE Podcast: Let's Get Digital: Psychiatric Therapeutics in a Digital World
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/psychiatric-therapeutics-in-a-digital-world-10096
Summary
In this PsychTalk podcast/webcast episode, Drs. Gregory Mattingly and Lisa Harding delve into the digital world and breakdown its effects on mental health—both positive and negative. By the end of the episode, learners will have a better understanding of the relationship between screen time, social media, and attention, including clinical pearls for how to harness prescription technology to enhance patient ou...
CME/CE Podcast: Schizophrenia: The Classic, The Innovative, and The Enduring
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/clinical-updates-in-schizophrenia-10097
Summary
In this PsychTalk podcast/webcast episode, Drs. Gregory Mattingly and Lisa Harding go through the evolving landscape of schizophrenia treatments. Listen as they discuss the pros and cons of various second-generation antipsychotics, the science behind muscarinic modulation for psychosis, and recent updates in clozapine prescribing. At the end of the session, the doctors answer several audience questions to enhance your understanding of...
APAPP Biologic Breakdown
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NACE Journal Club #18
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:
1. Adverse Outcomes Associated With Inhaled Corticosteroid Use in Individuals With Chronic Obstructive Pulmonary Disease. Annals of Family Medicine 2025. Discussion by:
Guest:
Barbara Yawn, MD, MSc, MPH
Adjunct Professor, Department of Family and Community Health
University of MinnesotaÂ
Former Chief Scientific Officer at the COPD Foundation
2. Optimal dietary patterns for h...
APAPP COPD Committee: GOLD 2025 Review
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CME/CE Podcast: Case by Case: Practical Management for Complex Psychiatric Cases
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/practical-management-for-complex-psychiatric-cases-10046
Summary
In this PsychTalk podcast/webcast episode, Drs. Gregory Mattingly and Lisa Harding teach by case example. Listeners will hear an introduction to a complex patient presentation and then be taken through expert strategies to discern the correct diagnoses. The program will conclude with the same case example to tie together the education and demonstrate these strategies in practice.
This podcast...
CME/CE Podcast: Characterizing Connected Conditions in Psychiatry
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/characterizing-connected-conditions-in-psychiatry-10045
Summary
In this PsychTalk podcast/webcast episode, Drs. Gregory Mattingly and Lisa Harding discuss some of the complexities of mental health care: overlapping symptoms and differential diagnoses. Listeners will learn about the connections between certain psychiatric disorders and how symptom combinations may influence treatment and patient outcomes. The program will also review strategies to help with accurate diagnoses in complex patient presentations, teaching...
NACE Journal Club #17
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:
1. Filling the Evidence Gaps Toward a Coronary Artery Calcium-Guided Primary Prevention Strategy. JAMA Cardiology 2025. Discussion by:
Guest:
Michael J. Blaha, MD, MPH
Professor of Cardiology and Epidemiology and presently serves as theÂ
Director of Clinical Research for the
Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease
2. Male-Partner T...
APAPP Interventional Pulmonary Edition: Endobronchial Valves
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APAPP Asthma COPD Overlap
Please visit http://naceonline.com to engage in more live and on demand CME/CE content.