The NACE Clinical Highlights Show

Please visit http://naceonline.com to engage in more live and on demand CME/CE content.

The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:

1. Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function: The US POINTER Randomized Clinical Trial JAMA 2025.  Discussion by:
Guest:
Philip Lieberman, MD
Resident- Family Medicine Residency Program
Jefferson Health - Abington

2. Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity — A Phase 2 Trial.  New England Journal of Medicine 2025 Discussion by:

For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:

https://www.mycme.com/courses/targeting-cause-emerging-therapies-menopausal-vms-10267

Summary
This enduring podcast activity explores groundbreaking advancements in the treatment of menopausal vasomotor symptoms (VMS), emphasizing non-hormonal therapies. Dr. Andrea Singer and Dr. Genevieve Neal-Perry discuss the underlying biology of menopause, particularly the role of neurokinin (NK) receptors, and introduces the science behind new therapeutic agents, as well as their clinical trial data.

This podcast was recorded and is...

For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:

https://www.mycme.com/courses/personalizing-care-identifying-the-right-patients-for-new-treatments-10268

Summary
Dr. Genevieve Neal-Perry and Dr. Andrea Singer focus on practical strategies in the personalized management of menopausal vasomotor symptoms (VMS). The discussion covers the importance of routine and individualized screening for VMS, with attention to healthcare disparities and the diverse ways menopause is discussed and experienced across populations, before covering patient selection criteria for newer non-hormonal treatments.

This podcast...

Please visit http://naceonline.com to engage in more live and on demand CME/CE content.

The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:

1. Antihypertensive Medication Timing and Cardiovascular Events and Death The BedMed Randomized Clinical Trial JAMA 2025.  Discussion by:
Guest:
Susan Kuchera, MD
Director of the Family Medicine Residency Program
Jefferson Health - Abington

2. Weekly Fixed-Dose Insulin Efsitora in Type 2 Diabetes without Previous Insulin Therapy. 2025.  Discussion by:
Guest:
Eden Miller, MD...

For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:

http://mycme.com/courses/the-cognitive-side-of-major-depressive-disorder-10221

Summary
Despite significant improvements in mood symptoms, many patients with MDD continue to experience persistent residual symptoms—particularly cognitive impairments—that hinder full functional recovery. In this PsychTalk podcast/webcast episode, Drs. Gregory Mattingly and Roger McIntyre discuss the often-overlooked role of cognitive dysfunction in MDD recovery, highlighting how these impairments correlate strongly with reduced workplace productivity, social withdrawal, and elevated relapse risk, ulti...

For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:

https://www.mycme.com/courses/strategies-and-real-world-impact-of-the-stimulant-crisis-10220

Summary
The stimulant medication shortage has introduced new challenges in managing ADHD, affecting both patients’ access to essential treatments and clinicians’ ability to provide consistent care. In this PsychTalk podcast/webcast episode, Drs. Gregory Mattingly and Roger McIntyre explore the impact of these shortages, particularly on cognitive functioning, treatment continuity, and daily life for individuals with ADHD. Their discussion also examines stimulant misu...

For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/the-latest-data-in-ckd-progression-10197

Summary
Emerging evidence highlights the potential of GLP-1 receptor agonists (GLP-1 RAs) to slow CKD progression and reduce cardiovascular and kidney-related mortality in patients with type 2 diabetes (T2D) and chronic kidney disease (CKD). Yet, despite updated guidelines, these therapies remain underused. This program will explore the latest clinical data supporting the role of GLP-1 RAs in risk mitigation and provide practical strategies...

Please visit http://naceonline.com to engage in more live and on demand CME/CE content.

The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:

1. Effects of Combining Coronary Calcium Score With Treatment on Plaque
Progression in Familial Coronary Artery Disease A Randomized Clinical Trial JAMA 2025. Discussion by:
Guest:
Michael J. Blaha, MD, MPH
Professor of Cardiology and Epidemiology and presently serves as the
Director of Clinical Research for the Johns Hopkins Ciccarone Center for the
...

For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/answers-in-chronic-spontaneous-urticaria-10190

Summary
In this short CE/CME activity, moderator Dr. Brad Glick works with dermatology expert Dr. Gil Yosipovitch to answer your top questions regarding chronic spontaneous urticaria, as gathered from the 2025 NACE Conversations in Dermatology symposium. Questions cover diagnosis, treatment individualization, and more!

Learning Objectives
At the conclusion of this activity, participants should be better able to:

For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:
https://www.mycme.com/courses/copd-inflammation-exacerbations-your-questions-answered-10143

Summary
Rejoin the conversation on COPD, inflammation, and new and emerging agents as two of our expert faculty come together to answer your top questions. Questions submitted from the recent Conversations in Primary Care live virtual symposia guide the discussion as we dig a bit deeper on type 2 inflammation, changes in COPD management, and new and emerging agents – including recently approved biologic agents – for...

Please visit http://naceonline.com to engage in more live and on demand CME/CE content.

The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:

1. Lepodisiran — A Long-Duration Small Interfering RNA Targeting Lipoprotein(a) - New England Journal of Medicine 2025. Discussion by:
Guest:
Steven E. Nissen, M.D.,
 Chief Academic Officer of the Heart and Vascular Institute at the Cleveland Clinic
Professor of Medicine at the Lerner College of Medicine

2. Genitourinary Syndrome of Menopause: AUA/SUFU...