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In this episode of The Oncology Journal Club, the team weigh promising trial signals against the level of evidence needed to change clinical practice. From perioperative cholangiocarcinoma to molecular matching and chrono-oncology, the focus stays on a key question: what meaningfully improves outcomes for patients?

What’s covered

 NeoGOLP trial in high-risk resectable iCCA: improved event-free survival; overall survival still immature  MoST programme: molecular matching and survival associations when therapies align with biomarkers  Genomic therapy matching in clinical decision-making  Chrono-oncology: does treatment timing influence outcomes?  CHOPIN phase II uv...

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Proudly Produced by The Oncology Network

Professor Craig Underhill and Rachael Babin break down the key oncology changes from the April 2026 PBS update.

This month we run through six fresh PBS listings and policy changes that affect Australian oncology and haematology practice, from ROS1-positive non small cell lung cancer to perioperative immunotherapy and late-line blood cancer options. 

We focus on who benefits, what the key trial signals are and what clinicians need to monitor so access translates into safe, real-world o...

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Australia’s PBS has introduced it’s first pan-tumour reimbursement listing for the immunotherapy combination nivolumab plus ipilimumab. In this inaugural episode of PBS Update, Professor Craig Underhill and Rachael Babin break down the key oncology changes from the March 2026 PBS update, including new listings for toripalimab and cabozantinib.

Follow PBS Update for regular discussions on PBS listings and oncology policy changes affecting Australian healthcare professionals.

Visit the Show Notes for links to the PBS upda...

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The Oncology Journal Club Podcast hosted by Professor Craig Underhill, Dr Kate Clarke and Professor Chris Jackson | Proudly Produced by The Oncology Network

Visit oncologynetwork.com.au for Show Notes, to send us Voice Notes and more information. 

We explore practical wins and bold ideas across supportive care, colorectal cancer prevention, immunotherapy timing, digital triage and equity. From halving hot flushes with an NK1/NK3 blocker to biomarker-guided aspirin in colon cancer, we weigh value, risk and what truly improves lives.

• Elinzanetant cutting severe hot flu...

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Welcome back to The Oncology Journal Club podcast — our favourite episode of the year!

Hosted by Professor Craig Underhill, Dr Kate Clarke and Professor Christopher Jackson.

The team reflect on the achievements of 2025, highlighting key developments, initiatives and papers that have made — and will continue to make — a real impact on clinical practice. As CJ says, it’s a privilege to work in what is the “single most innovative and thoughtful field in all of medicine” — and we are indeed lucky to have our brains tic...

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Welcome to The Oncology Journal Club Podcast Series 3
Hosted by Professor Craig Underhill, Dr Kate Clarke & Professor Christopher Jackson | Proudly produced by The Oncology Network

Welcome back to The Oncology Journal Club podcast, your essential dose of the latest oncology research, expert analysis and our trademark blend of healthy scepticism and bad jokes.

Hosted by Professor Craig Underhill, Dr Kate Clarke and Professor Christopher Jackson.

This week’s episode really does contain multitudes, with an incredibly eclectic mix of papers.

Craig looks at th...

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Welcome to The Oncology Journal Club Podcast Series 3
Hosted by Professor Craig Underhill, Dr Kate Clarke & Professor Christopher Jackson | Proudly produced by The Oncology Network

Kate Clarke takes over hosting duties!

Join our expert trio — Professor Craig Underhill, Dr Kate Clarke and Professor Christopher Jackson — for the usual OJC antics in Part 2 of our ESMO Special.

Craig talks us through the GU and lung highlights, while the team each share their top ‘practice-changing’ abstracts. Plus, CJ chats with Susie Stanway about the upcoming...

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Welcome to The Oncology Journal Club Podcast Series 3
Hosted by Professor Craig Underhill, Dr Kate Clarke & Professor Christopher Jackson | Proudly produced by The Oncology Network

Are you ready for some ESMO Bingo? Yes—it’s that time of year again!

Join our expert hosts Professor Craig Underhill, Dr. Kate Clarke and Professor Christopher Jackson for the usual OJC antics. 

This is Part 1 of our ESMO Special, where the team cover ovarian, breast, melanoma and GI. Expect the usual nuanced analysis and a few n...

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Welcome to Episode 29 of The Oncology Podcast’s Experts On Point series, brought to you by The Oncology Network.

AGITG ASM 2025 Special | 24–27 November | Tarntanya (Adelaide), South Australia

The most exciting ideas in GI oncology rarely come from just one room—or even one country. In this episode, host Rachael Babin sits down with Associate Professor Sina Vatandoust, Convenor of the AGITG 2025 ASM, and Associate Professor Margaret Lee, one of this year’s local speakers. Together, they share a preview of the u...

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Welcome to The Oncology Journal Club Podcast Series 3
Hosted by Professor Craig Underhill, Dr Kate Clarke & Professor Christopher Jackson | Proudly produced by The Oncology Network

Welcome to Episode 7 of The Oncology Journal Club podcast. This is where we take a famously different approach to oncology research.

Join our expert hosts as they navigate the latest developments with their trademark blend of critical analysis, clinical wisdom and humour. With this in mind please note: Warning: This episode does contain some strong language.

This...

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Welcome to the latest Series of Supportive Care Matters, a podcast hosted by Medical Oncologist and International Cancer Survivorship Expert, Professor Bogda Koczwara AM.

"If it were a pill, we would all want it." This powerful opening statement captures the essence of ground-breaking research that's transforming our understanding of cancer survivorship care. The CHALLENGE Study has delivered what many considered impossible: definitive evidence that structured exercise significantly extends the lives of colorectal cancer survivors.

The results are nothing short of remarkable. Colorectal cancer patients who participated in...

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Proudly produced by The Oncology Network

When does aggressive cancer treatment shift from beneficial to harmful? This powerful conversation between Professor Nathan Cherny and Professor Christopher Jackson tackles one of oncology's most challenging ethical dilemmas – overtreatment at the end of life.

Drawing on his extensive experience and research, Professor Cherny illuminates the complex factors driving excessive treatment, from departmental culture to cognitive biases. 

"Oncologists need to learn not only when to treat, but when not to treat," he emphasises, highlighting how treatment decisions for poor-performance sta...

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Welcome to The Oncology Journal Club Podcast Series 3
Hosted by Professor Craig Underhill, Dr Kate Clarke & Professor Christopher Jackson | Proudly produced by The Oncology Network

Welcome to Episode 6 of The Oncology Journal Club podcast. This is where we take a famously different approach to oncology research.

Has non-operative management finally found its place in treating certain cancers? This episode unpacks compelling new data that might challenge the surgeon's traditional role for some patients with mismatch repair deficient tumours. While rectal cancer patients show remarkable complete response...

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Welcome to The Oncology Journal Club Podcast Series 3
Hosted by Professor Craig Underhill, Dr Kate Clarke & Professor Christopher Jackson | Proudly produced by The Oncology Network

Welcome to the Oncology Journal Club ASCO 2025 Special – Part 2! This is where we take a famously different approach to oncology research.

If you're after an enlightening and entertaining take on this year’s ASCO meeting, the OJC team has you covered – blending expert analysis with trademark humour.

Our hosts go beyond the standard presentations to explore what the research really...

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Welcome to The Oncology Journal Club Podcast Series 3
Hosted by Professor Craig Underhill, Dr Kate Clarke & Professor Christopher Jackson | Proudly produced by The Oncology Network

Welcome to the Oncology Journal Club ASCO 2025 Special – Part 1! This is where we take a famously different approach to oncology research.

If you're after an enlightening and entertaining take on this year’s ASCO meeting, the OJC team has you covered – blending expert analysis with trademark humour.

Our hosts go beyond the standard presentations to explore what the research really...

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Welcome to the latest Series of Supportive Care Matters, a podcast hosted by Medical Oncologist and International Cancer Survivorship Expert, Professor Bogda Koczwara AM.

The landscape of cancer survivorship is evolving before our eyes. As treatment advances allow people with metastatic cancer to live longer, we're witnessing the emergence of a population that exists in what medical oncologist Dr Lori Spoozak calls "the place in between" – not curable but not actively dying.

In this eye-opening conversation, researchers Associate Professor Nick Hart and Dr. Andrea Smith (who herself lives with me...

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Welcome to Episode 29 of The Oncology Podcast's Experts On Point series, brought to you by The Oncology Network. Hosted by Rachael Babin.

How do we tackle inequities in cancer care? What role do collaborative networks play in ensuring better outcomes for patients and their families? And how can molecular tumour boards bridge the gap for those outside metropolitan areas, giving them access to life-saving treatments and clinical trials?

To explore these critical q...

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Welcome to The Oncology Journal Club Podcast Series 3
Hosted by Professor Craig Underhill, Dr Kate Clarke & Professor Christopher Jackson | Proudly produced by The Oncology Network

The Oncology Journal Club team take a deep dive into three standout papers:

Craig kicks us off with a timely perspective on the long-term toxicity of immune checkpoint inhibitors—are we ready to widen the lens? He highlights the need for more comprehensive research on survivorship issues including quality of life, financial impact and psychological outcomes.Kate brings us the exciting results fr...

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Welcome to The Oncology Journal Club Podcast Series 3
Hosted by Professor Craig Underhill, Dr Kate Clarke & Professor Christopher Jackson | Proudly produced by The Oncology Network

The Oncology Journal Club hosts break from their usual format to discuss the impact of political shifts on diversity, equity and inclusion in cancer research and treatment worldwide.

Recent political developments threaten progress in cancer research, particularly through attacks on the NIH, CDC and other scientific institutionsEvidence shows that diversity in healthcare leadership leads to better patient outcomes and financial performanceCensorship of...

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Welcome to The Oncology Journal Club Podcast Series 3! Proudly produced by The Oncology Network

Three respected oncologists dive deep into the most significant research presented at ASCO GI 2025, bringing you practice-changing insights amidst a backdrop of political uncertainty affecting medical research.

Professor Chris Karapetis joins hosts Professor Craig Underhill and Professor Christopher Jackson to unpack ground-breaking colorectal cancer studies that are reshaping treatment paradigms. The conversation explores how targeted therapies are dramatically improving survival rates, with the DEEPER study demonstrating cetuximab's superiority over bevacizumab for left-sided RAS...

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Confronting the Fear of Cancer Recurrence

Welcome to the latest Series of Supportive Care Matters, a podcast hosted by Medical Oncologist and International Cancer Survivorship Expert, Professor Bogda Koczwara AM.

The fear of cancer returning is a silent struggle for many survivors, often overshadowing their recovery. In Episode 1 of this new Series, Bogda explores this deep-seated anxiety with experts Professor Sophie Lebel and Associate Professor Ben Smith.

They unpack the realities of recurrence fears — why they persist, who is most affected and how they impact da...

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G’day G’day G’day! Or should we say Ho! Ho! Ho!

Welcome to The Oncology Journal Club Podcast’s Christmas Special!

Where we take our fun and educational oncology learning resource for medical professionals to new festive heights.

Produced by Rachael Babin, from The Oncology Podcast. Joined by our esteemed hosts: Professor Craig Underhill, Dr. Kate Clarke, and Professor Christopher Jackson.

Join us as we reflect on the year's most impactful studies and developments of 2024. You'll discover the best papers of the year, th...

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What if we told you that cancer care could be kinder to both the planet and the patient? Join us for another enlightening and educational conversation with Professor Craig Underhill, Dr. Kate Clarke and Professor Christopher Jackson.

Laugh along with Craig who, despite battling 'man flu,' sheds light on reducing the climate toxicity of cancer care. Meanwhile, Kate reassures listeners by debunking myths about the safety of oestrogens in hormone replacement therapy and IVF in patients with breast cancer, shifting focus to the real culprit—progesterone. CJ guides you through th...

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As we head toward the end of the year, the Oncology Journal Club Podcast team reflect on learnings from the last big international conference of the year.

With 15 papers across various specialties, we've got you covered with an insightful exploration of all the pivotal studies. You can expect expert analysis alongside our unique blend of humour, banter and bad dad jokes.

With our incredible Hosts - Professor Craig Underhill, Dr Kate Clarke and Professor Christopher Jackson.

For papers, bios and other links visit the Show Notes on...

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Welcome to Episode 28 of The Oncology Podcast's Experts On Point series, brought to you by The Oncology Network. Hosted by Rachael Babin.

Are you talking to your patients about sex enough? Research suggests that most healthcare professionals aren’t having these conversations as often as patients would like. 

Sexual health should be a core component of holistic patient care.

To shed light on this critical topic, Rachael is joined by Asso...

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Unlock the secrets of the ever-evolving oncology landscape as Professor Craig Underhill, Dr Kate Clarke and Professor Christopher Jackson take us through another brilliant OJC update.

Craig reviews new sarcoma research and also looks at a mortality comparison study of six high-income Anglophone countries. Kate delves into the exciting advancements in precision oncology, particularly the impacts of on children, adolescents, and young adults. CJ looks at a groundbreaking cohort study from Christchurch, New Zealand, revealing how Faecal Immunochemical Tests (FIT) could revolutionise colonoscopy referrals and optimise healthcare resources.

Craig...

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Curious about the latest breakthroughs in oncology treatment? Prepare to have your perspective shifted and hopefully a few laughs too, as we dissect the most compelling research and clinical insights with our expert hosts, Professor Craig Underhill, Dr. Kate Clarke, and Professor Christopher 'CJ' Jackson.

Today’s episode covers an eclectic mix of papers. Craig tackles patient-reported outcomes. Kate looks at oral cannabis for nausea and vomiting. And CJ reviews the ASCO Guidelines for the management of locally advanced rectal cancer. 

Plus each Host presents their favourite Quick Bite pap...

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Curious about the latest breakthroughs in oncology treatment? Prepare to have your perspective shifted and hopefully a few laughs too, as we dissect the most compelling research and clinical insights with our expert hosts, Professor Craig Underhill, Dr. Kate Clarke, and Professor Christopher Jackson. 

Today’s episode covers an eclectic mix of papers from many different specialities. Craig tackles ASCO non-small cell lung cancer recommendations, sarcomas in Brazil and cardiovascular risks in cancer patients.

Kate dives into endometrial cancer, the HIMALAYA study and CAR-T.

CJ looks at col...

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Welcome to the latest episode of Supportive Care Matters. Join Medical Oncologist Professor Bogda Koczwara AM and Dr. David Mizrahi,  Exercise Physiologist and Research Fellow at the Daffodil Center, University of Sydney. 

Learn how precisely prescribed exercise can transform not just the physical health but also the clinical outcomes for cancer patients. We break down the distinctions between exercise and physical activity, showing how each contributes uniquely to improved mood, heart health, muscle strength and metabolic health. 

Dr. Mizrahi shares ground-breaking insights on how integrating exercise into cancer treatment reg...

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Discover the latest breakthroughs from ASCO 2024 with The Oncology Journal Club team!

Professor Chris Jackson, who, despite battling the infamous man flu, brings his A-game to dissect the NADINA study. Learn how neoadjuvant ipilimumab and nivolumab are transforming resectable stage 3 melanoma treatment with a remarkable 26 percentage point gain in 12-month event-free survival. Chris shines a spotlight on the innovative design of this trial and its promising implications for reducing treatment duration and financial strain.

But that's just the beginning. Dive into the long-term data from the COMBI-AD study, where...

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Imagine having the latest breakthroughs in oncology from the ASCO 2024 conference delivered with humour, expert insight and personal stories. That's exactly what you'll get in this special episode of the Oncology Journal Club, where Professor Craig Underhill, Dr. Kate Clark, and Professor Christopher Jackson dissect the most impactful research in a uniquely engaging way. 

Going beyond the usual presentations, with analysis of practice changing presentations aka 'The Bangers!'

From Professor Jackson's cultural adventures in Invercargill to Dr. Clark's firsthand experiences on the bustling floors of Chicago's conference halls, w...

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Welcome to the latest episode of Supportive Care Matters. Join Medical Oncologist Professor Bogda Koczwara AM and advocate Matthew Zachary, founder of Stupid Cancer and the creative force behind the documentary "Cancer Mavericks." 

Matthew shares the profound journeys of pioneers who transformed cancer survivorship from the 1960s to the present day. From exhaustive research to heartwarming interviews, discover the intricate process of honouring those who fought tirelessly to improve the lives of cancer patients and survivors.

This episode traces the evolution of cancer survivorship, from the early days of m...

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Join us on this episode of The Oncology Journal Club Podcast as we dissect the latest research that point to new standards of care.

Join our esteemed Hosts, Professor Craig Underhill, Dr. Kate Clarke and Professor Christopher Jackson for the low down on the latest oncology papers.

Craig looks at how three-agent regimens have revolutionised the treatment of metastatic hormone-sensitive prostate cancer.  Kate asks how alcohol affects lethal prostate cancer risk.  And CJ explores the promising results of adjuvant pembrolizumab in resected renal cell carcinoma with his typical in-depth, hi...

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Welcome to the latest episode of Supportive Care Matters. Join Medical Oncologist Professor Bogda Koczwara AM and Dr. Wanda Cui as they dive deep into the often overlooked complexities of ovarian toxicity in cancer care.

In this engaging conversation, Bogda and Wanda go beyond the surface discussions of fertility to explore the vital importance of a woman's overall ovarian health after cancer treatment. They discuss the far-reaching effects of early menopause triggered by cancer therapies on cardiovascular and bone health, shedding light on the significance of safeguarding reproductive potential through fertility...

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How do cancer outcomes in New Zealand compare to Australia? How can we optimise post-neoadjuvant treatment in patients with early breast cancer who achieve pathologic complete response? Does bevacizumab improve efficacy when administered with platinum combination therapy and atezolizumab in patients with advanced nonsquamous non small cell lung cancer? And how do AI chatbots perform when asked for cancer treatment recommendations?

Welcome to The Oncology Journal Club Podcast – your go-to source for in-depth discussions on the latest oncology research tailored for medical professionals.

Join our esteemed Hosts, Professor Craig Un...

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Welcome to the ninth episode of Supportive Care Matters, a podcast Hosted by Medical Oncologist Professor Bogda Koczwara AM from Adelaide, Australia.

Navigating the silent struggle that many cancer survivors face, this episode promises insights into the lesser-known yet impactful world of chemotherapy-induced peripheral neuropathy (CIPN).

With the expertise of Professor David Goldstein and Associate Professor Susanna Park, this episode sheds light on how CIPN disrupts daily life in ways that go unnoticed by the medical community.

From the nuanced challenges of assessing the severity of this...

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The Oncology Journal Club - Delivering Oncology News Differently

The Oncology Podcast, part of The Oncology Network, is proud to present Episode 3 in the second series of The Oncology Journal Club Podcast.

Dr Kate Clarke explores a clinical conundrum with the latest insights on neo-adjuvant immunotherapy for DMMR, MSI-high GI cancers, discussed with the clarity and depth you've come to expect from our team. For Professor Craig Underhill's main paper segment, Dr. Ashray Gunjur drops by to discuss the microbiome's predictive power in immunotherapy responses, Professor Christopher...